Stephen D Fuller

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi request reprint Depositing electron microscopy maps
    Stephen D Fuller
    Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom
    Structure 11:11-2. 2003
  2. ncbi request reprint Cryo-electron microscopy reveals conserved and divergent features of gag packing in immature particles of Rous sarcoma virus and human immunodeficiency virus
    John A G Briggs
    Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, UK
    J Mol Biol 355:157-68. 2006
  3. pmc Post-imaging fiducial markers aid in the orientation determination of complexes with mixed or unknown symmetry
    Doryen Bubeck
    Division of Structural Biology, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, University of Oxford, Oxford OX3 7BN, UK
    J Struct Biol 162:480-90. 2008
  4. pmc Human T-lymphotropic virus-1 visualized at the virological synapse by electron tomography
    Endre Majorovits
    Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
    PLoS ONE 3:e2251. 2008
  5. ncbi request reprint The mechanism of HIV-1 core assembly: insights from three-dimensional reconstructions of authentic virions
    John A G Briggs
    Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, Oxford OX3 7BN, UK
    Structure 14:15-20. 2006
  6. ncbi request reprint Determination of astigmatism in TEM images
    K Vince Fernando
    Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, UK
    J Struct Biol 157:189-200. 2007
  7. pmc Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situ
    Giulia Zanetti
    University of Oxford, Division of Structural Biology, Wellcome Trust Centre for Human Genetics, Henry Wellcome Building for Genomic Medicine, Headington, United Kingdom
    PLoS Pathog 2:e83. 2006
  8. ncbi request reprint Classification and three-dimensional reconstruction of unevenly distributed or symmetry mismatched features of icosahedral particles
    John A G Briggs
    Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, UK
    J Struct Biol 150:332-9. 2005
  9. ncbi request reprint Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues
    Rene Assenberg
    Oxford Protein Production Facility, The Henry Wellcome Building for Genomic Medicine, Oxford University, Roosevelt Drive, Oxford OX3 7BN, UK
    J Gen Virol 88:2228-36. 2007
  10. pmc Structural organization of authentic, mature HIV-1 virions and cores
    John A G Briggs
    The Wellcome Trust Centre for Human Genetics, Division of Structural Biology, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, UK
    EMBO J 22:1707-15. 2003

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Depositing electron microscopy maps
    Stephen D Fuller
    Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom
    Structure 11:11-2. 2003
    ..The meeting concluded with a strong endorsement of map deposition in electron microscopy and its linkage with the family of archival databases in biomedical research...
  2. ncbi request reprint Cryo-electron microscopy reveals conserved and divergent features of gag packing in immature particles of Rous sarcoma virus and human immunodeficiency virus
    John A G Briggs
    Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, UK
    J Mol Biol 355:157-68. 2006
    ....
  3. pmc Post-imaging fiducial markers aid in the orientation determination of complexes with mixed or unknown symmetry
    Doryen Bubeck
    Division of Structural Biology, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, University of Oxford, Oxford OX3 7BN, UK
    J Struct Biol 162:480-90. 2008
    ..The analysis reported here, and its subsequent application to enveloped virus fusion, indicate that this is a robust tool for solving the structures of mixed-symmetry complexes...
  4. pmc Human T-lymphotropic virus-1 visualized at the virological synapse by electron tomography
    Endre Majorovits
    Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
    PLoS ONE 3:e2251. 2008
    ....
  5. ncbi request reprint The mechanism of HIV-1 core assembly: insights from three-dimensional reconstructions of authentic virions
    John A G Briggs
    Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, Oxford OX3 7BN, UK
    Structure 14:15-20. 2006
    ..This mechanism accommodates significant flexibility in lattice growth while ensuring the closure of cores of variable size and shape...
  6. ncbi request reprint Determination of astigmatism in TEM images
    K Vince Fernando
    Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, UK
    J Struct Biol 157:189-200. 2007
    ..Our algorithm is tested on astigmatic images of carbon film, 2D crystals of bacteriorhodopsin and cryo-images of HIV cores...
  7. pmc Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situ
    Giulia Zanetti
    University of Oxford, Division of Structural Biology, Wellcome Trust Centre for Human Genetics, Henry Wellcome Building for Genomic Medicine, Headington, United Kingdom
    PLoS Pathog 2:e83. 2006
    ..A cavity exists at the gp41-gp120 trimer interface. Our model for the spike structure agrees with previously predicted interactions between gp41 monomers, and furthers our understanding of gp120 interactions within an intact spike...
  8. ncbi request reprint Classification and three-dimensional reconstruction of unevenly distributed or symmetry mismatched features of icosahedral particles
    John A G Briggs
    Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, UK
    J Struct Biol 150:332-9. 2005
    ..In this case, each virion may have two different types of fivefold vertex. We use our approach to produce independent reconstructions of the two types of vertex...
  9. ncbi request reprint Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues
    Rene Assenberg
    Oxford Protein Production Facility, The Henry Wellcome Building for Genomic Medicine, Oxford University, Roosevelt Drive, Oxford OX3 7BN, UK
    J Gen Virol 88:2228-36. 2007
    ....
  10. pmc Structural organization of authentic, mature HIV-1 virions and cores
    John A G Briggs
    The Wellcome Trust Centre for Human Genetics, Division of Structural Biology, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, UK
    EMBO J 22:1707-15. 2003
    ..The extraordinary flexibility observed in the assembly of the mature core appears to be well suited to accommodating variation and hence there may be no single structure for the infectious virion...