- Evolution of lamivudine resistance in human immunodeficiency virus type 1-infected individuals: the relative roles of drift and selectionS D Frost
Centre for HIV Research, Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh, Scotland
J Virol 74:6262-8. 2000..These results show that stochastic effects can be significant in HIV evolution, even when there is large fitness difference between mutant and wild-type variants...
- Evidence for positive selection driving the evolution of HIV-1 env under potent antiviral therapyS D Frost
Centre for HIV Research, University of Edinburgh, Scotland
Virology 284:250-8. 2001....