Jennifer M Frost

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc The effects of culture on genomic imprinting profiles in human embryonic and fetal mesenchymal stem cells
    Jennifer Frost
    Institute of Reproductive and Developmental Biology, Imperial Colleg, London, UK
    Epigenetics 6:52-62. 2011
  2. pmc The importance of imprinting in the human placenta
    Jennifer M Frost
    Clinical and Molecular Genetics Unit, Institute of Child Health, University College London, London, United Kingdom
    PLoS Genet 6:e1001015. 2010
  3. pmc Telomeric NAP1L4 and OSBPL5 of the KCNQ1 cluster, and the DECORIN gene are not imprinted in human trophoblast stem cells
    Jennifer M Frost
    Clinical and Molecular Genetics Unit, Institute of Child Health, University College London, London, UK
    PLoS ONE 5:e11595. 2010
  4. pmc Evaluation of allelic expression of imprinted genes in adult human blood
    Jennifer M Frost
    Clinical and Molecular Genetics Unit, Institute of Child Health, University College London, London, United Kingdom
    PLoS ONE 5:e13556. 2010

Detail Information

Publications4

  1. pmc The effects of culture on genomic imprinting profiles in human embryonic and fetal mesenchymal stem cells
    Jennifer Frost
    Institute of Reproductive and Developmental Biology, Imperial Colleg, London, UK
    Epigenetics 6:52-62. 2011
    ..Since DMR integrity was maintained in fMSC but not hES cells, we postulate that specific hES cell derivation and culturing practices result in changes in methylation at DMRs...
  2. pmc The importance of imprinting in the human placenta
    Jennifer M Frost
    Clinical and Molecular Genetics Unit, Institute of Child Health, University College London, London, United Kingdom
    PLoS Genet 6:e1001015. 2010
    ..Finally, we illustrate the importance of imprinting in the postnatal human in terms of several human imprinting disorders, with consideration of the brain as a key organ for imprinted gene expression after birth...
  3. pmc Telomeric NAP1L4 and OSBPL5 of the KCNQ1 cluster, and the DECORIN gene are not imprinted in human trophoblast stem cells
    Jennifer M Frost
    Clinical and Molecular Genetics Unit, Institute of Child Health, University College London, London, UK
    PLoS ONE 5:e11595. 2010
    ..However, as early development is less divergent between species, placental specific imprinting may be present in very early gestation in both mice and humans...
  4. pmc Evaluation of allelic expression of imprinted genes in adult human blood
    Jennifer M Frost
    Clinical and Molecular Genetics Unit, Institute of Child Health, University College London, London, United Kingdom
    PLoS ONE 5:e13556. 2010
    ..In general, the expression profiles of imprinted genes are well characterised during human and mouse fetal development, but not in human adults...