K Friston

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Striatal prediction error modulates cortical coupling
    Hanneke E M den Ouden
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, United Kingdom
    J Neurosci 30:3210-9. 2010
  2. pmc The history of the future of the Bayesian brain
    Karl Friston
    The Wellcome Trust Centre for Neuroimaging, UCL, 12 Queen Square, London WC1N 3BG, UK
    Neuroimage 62:1230-3. 2012
  3. pmc Waking and dreaming consciousness: neurobiological and functional considerations
    J A Hobson
    Division of Sleep Medicine, Harvard Medical School, Boston, MA 02215, USA
    Prog Neurobiol 98:82-98. 2012
  4. doi request reprint Functional and effective connectivity: a review
    Karl J Friston
    The Wellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom
    Brain Connect 1:13-36. 2011
  5. pmc Dopamine, affordance and active inference
    Karl J Friston
    The Wellcome Trust Centre for Neuroimaging, University College London, Queen Square, London, United Kingdom
    PLoS Comput Biol 8:e1002327. 2012
  6. pmc Free energy, value, and attractors
    Karl Friston
    The Wellcome Trust Centre for Neuroimaging, UCL, Institute of Neurology, 12 Queen Square, London WC1N 3BG, UK
    Comput Math Methods Med 2012:937860. 2012
  7. doi request reprint DEM: a variational treatment of dynamic systems
    K J Friston
    The Wellcome Department of Imaging Neuroscience, University College London, United Kingdom
    Neuroimage 41:849-85. 2008
  8. ncbi request reprint Multiple sparse priors for the M/EEG inverse problem
    Karl Friston
    The Wellcome Trust Centre for Neuroimaging, Institute of Neurology, UCL, 12 Queen Square, London, WC1N 3BG, UK
    Neuroimage 39:1104-20. 2008
  9. ncbi request reprint A free energy principle for the brain
    Karl Friston
    The Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3B, United Kingdom
    J Physiol Paris 100:70-87. 2006
  10. ncbi request reprint Variational free energy and the Laplace approximation
    Karl Friston
    The Wellcome Department of Imaging Neuroscience, Institute of Neurology, UCL, 12 Queen Square, London, WC1N 3BG, UK
    Neuroimage 34:220-34. 2007

Collaborators

Detail Information

Publications137 found, 100 shown here

  1. pmc Striatal prediction error modulates cortical coupling
    Hanneke E M den Ouden
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, United Kingdom
    J Neurosci 30:3210-9. 2010
    ..This finding substantially advances our understanding of striatal function and provides direct empirical evidence for formal learning theories that posit a central role for prediction error-dependent plasticity...
  2. pmc The history of the future of the Bayesian brain
    Karl Friston
    The Wellcome Trust Centre for Neuroimaging, UCL, 12 Queen Square, London WC1N 3BG, UK
    Neuroimage 62:1230-3. 2012
    ..I cannot imagine an alternative future that has the same beautiful self consistency as mine. Having dispensed with the future, we can now focus on the past, which is much more interesting:..
  3. pmc Waking and dreaming consciousness: neurobiological and functional considerations
    J A Hobson
    Division of Sleep Medicine, Harvard Medical School, Boston, MA 02215, USA
    Prog Neurobiol 98:82-98. 2012
    ....
  4. doi request reprint Functional and effective connectivity: a review
    Karl J Friston
    The Wellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom
    Brain Connect 1:13-36. 2011
    ..I accepted the invitation to write this review with great pleasure and hope to celebrate and critique the achievements to date, while addressing the challenges ahead...
  5. pmc Dopamine, affordance and active inference
    Karl J Friston
    The Wellcome Trust Centre for Neuroimaging, University College London, Queen Square, London, United Kingdom
    PLoS Comput Biol 8:e1002327. 2012
    ..We use these simulations to demonstrate how a single functional role for dopamine at the synaptic level can manifest in different ways at the behavioural level...
  6. pmc Free energy, value, and attractors
    Karl Friston
    The Wellcome Trust Centre for Neuroimaging, UCL, Institute of Neurology, 12 Queen Square, London WC1N 3BG, UK
    Comput Math Methods Med 2012:937860. 2012
    ....
  7. doi request reprint DEM: a variational treatment of dynamic systems
    K J Friston
    The Wellcome Department of Imaging Neuroscience, University College London, United Kingdom
    Neuroimage 41:849-85. 2008
    ..Furthermore, it provides for dual and triple inferences on a system's states, parameters and hyperparameters using exactly the same principles. We refer to this approach as dynamic expectation maximisation (DEM)...
  8. ncbi request reprint Multiple sparse priors for the M/EEG inverse problem
    Karl Friston
    The Wellcome Trust Centre for Neuroimaging, Institute of Neurology, UCL, 12 Queen Square, London, WC1N 3BG, UK
    Neuroimage 39:1104-20. 2008
    ..This means the approach automatically selects either a sparse or a distributed model, depending on the data. The scheme is compared with conventional applications of Bayesian solutions to quantify the improvement in performance...
  9. ncbi request reprint A free energy principle for the brain
    Karl Friston
    The Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3B, United Kingdom
    J Physiol Paris 100:70-87. 2006
    ..We will look at the models entailed by the brain and how minimisation of its free energy can explain its dynamics and structure...
  10. ncbi request reprint Variational free energy and the Laplace approximation
    Karl Friston
    The Wellcome Department of Imaging Neuroscience, Institute of Neurology, UCL, 12 Queen Square, London, WC1N 3BG, UK
    Neuroimage 34:220-34. 2007
    ..Finally, we also consider, briefly, dynamic models and how these inform the regularisation of free energy ascent schemes, like EM and ReML...
  11. ncbi request reprint A critique of functional localisers
    K J Friston
    The Wellcome Department of Imaging Neuroscience, Institute of Neurology, UCL, 12 Queen Square, London WC1N 3BG, UK
    Neuroimage 30:1077-87. 2006
    ..We conclude that localiser scans can be unnecessary and, in some instances, lead to a biased and inappropriately constrained characterisation of functional anatomy...
  12. doi request reprint The free-energy principle: a unified brain theory?
    Karl Friston
    The Wellcome Trust Centre for Neuroimaging, University College London, Queen Square, London, WC1N 3BG, UK
    Nat Rev Neurosci 11:127-38. 2010
    ..This is the quantity that is optimized under the free-energy principle, which suggests that several global brain theories might be unified within a free-energy framework...
  13. pmc A theory of cortical responses
    Karl Friston
    The Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
    Philos Trans R Soc Lond B Biol Sci 360:815-36. 2005
    ..The final focus of this article is on perceptual learning as measured with the MMN and the implications for empirical studies of coupling among cortical areas using evoked sensory responses...
  14. ncbi request reprint Bayesian decoding of brain images
    Karl Friston
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, UCL, 12 Queen Square, London WC1N 3BG, UK
    Neuroimage 39:181-205. 2008
    ..We illustrate MVB using simulated and real data, with a special focus on model comparison; where models can differ in the form of the mapping (i.e., neuronal representation) within one region, or in the (combination of) regions per se...
  15. ncbi request reprint Models of brain function in neuroimaging
    Karl J Friston
    Wellcome Department of Cognitive Neurology, University College London, London WC1N 3BG, UK
    Annu Rev Psychol 56:57-87. 2005
    ..By incorporating biophysical constraints, these basic models can be finessed and, in a dynamic setting, rendered causal. This allows us to infer how interactions among brain regions are mediated...
  16. ncbi request reprint Generative and recognition models for neuroanatomy
    K J Friston
    The Wellcome Department of Imaging Neuroscience, University of London, Institute of Neurology, London, UK WC1N 3BG
    Neuroimage 23:21-4. 2004
  17. ncbi request reprint Dynamic causal modelling
    K J Friston
    The Wellcome Department of Imaging Neuroscience, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    Neuroimage 19:1273-302. 2003
    ..psychophysiologic interactions). However, unlike previous approaches in neuroimaging, the causal model ascribes responses to designed deterministic inputs, as opposed to treating inputs as unknown and stochastic...
  18. doi request reprint Variational filtering
    K J Friston
    The Wellcome Deptartment of Imaging Neuroscience, University College London, United Kingdom
    Neuroimage 41:747-66. 2008
    ....
  19. doi request reprint Neurophysiology: the brain at work
    Karl Friston
    Wellcome Trust for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London, UK
    Curr Biol 18:R418-20. 2008
    ....
  20. pmc Post hoc Bayesian model selection
    Karl Friston
    The Wellcome Trust Centre for Neuroimaging, University College London, Queen Square, London, UK
    Neuroimage 56:2089-99. 2011
    ..We illustrate the approach using general linear models and a more complicated nonlinear state-space model...
  21. pmc Modules and brain mapping
    Karl J Friston
    The Wellcome Trust Centre for Neuroimaging, University College London, London, UK
    Cogn Neuropsychol 28:241-50. 2011
    ....
  22. pmc Action understanding and active inference
    Karl Friston
    The Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, Queen Square, UK
    Biol Cybern 104:137-60. 2011
    ..Our results affirm that a Bayes-optimal approach provides a principled framework, which accommodates current thinking about the mirror-neuron system. Furthermore, it endorses the general formulation of action as active inference...
  23. pdf Action and behavior: a free-energy formulation
    Karl J Friston
    The Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London, WC1N 3BG, UK
    Biol Cybern 102:227-60. 2010
    ..In short, the free-energy formulation may provide an alternative perspective on the motor control that places it in an intimate relationship with perception...
  24. pmc Computational and dynamic models in neuroimaging
    Karl J Friston
    The Wellcome Trust Centre for Neuroimaging, University College London, UK
    Neuroimage 52:752-65. 2010
    ..e., hypothesis testing). We will refer to this theme, when trying to contextualise recent trends in relation to each other...
  25. doi request reprint Modalities, modes, and models in functional neuroimaging
    Karl J Friston
    Wellcome Trust Centre for Neuroimaging, University College London, Queen Square, London WC1N 3BG, UK
    Science 326:399-403. 2009
    ....
  26. pmc Reinforcement learning or active inference?
    Karl J Friston
    The Wellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom
    PLoS ONE 4:e6421. 2009
    ..The ensuing proof-of-concept may be important because the free-energy formulation furnishes a unified account of both action and perception and may speak to a reappraisal of the role of dopamine in the brain...
  27. pmc Cortical circuits for perceptual inference
    Karl Friston
    The Wellcome Trust Centre of Neuroimaging, University College London, Queen Square, London, United Kingdom
    Neural Netw 22:1093-104. 2009
    ..We then show that the brain has the necessary infrastructure to implement this inversion and present stimulations using synthetic birds that generate and recognise birdsongs...
  28. doi request reprint The free-energy principle: a rough guide to the brain?
    Karl Friston
    The Wellcome Trust Centre for Neuroimaging, University College London, Queen Square, London WC1N 3BG, UK
    Trends Cogn Sci 13:293-301. 2009
    ..Furthermore, one can see easily how constructs like memory, attention, value, reinforcement and salience might disclose their simple relationships within this framework...
  29. pmc Predictive coding under the free-energy principle
    Karl Friston
    The Wellcome Trust Centre of Neuroimaging, Institute of Neurology, University College LondonQueen Square, London, UK
    Philos Trans R Soc Lond B Biol Sci 364:1211-21. 2009
    ..We then show that the brain has the necessary infrastructure to implement this inversion and illustrate this point using synthetic birds that can recognize and categorize birdsongs...
  30. pmc Hierarchical models in the brain
    Karl Friston
    The Wellcome Trust Centre of Neuroimaging, University College London, London, United Kingdom
    PLoS Comput Biol 4:e1000211. 2008
    ..We then show that this inversion can be formulated as a simple neural network and may provide a useful metaphor for inference and learning in the brain...
  31. ncbi request reprint Posterior probability maps and SPMs
    K J Friston
    The Wellcome Department of Imaging Neuroscience, London, Queen Square, London WC1N 3BG, UK
    Neuroimage 19:1240-9. 2003
    ..We then compare Bayesian and classical inference through the equivalent PPMs and SPMs testing for the same effect in the same data...
  32. ncbi request reprint Brain function, nonlinear coupling, and neuronal transients
    K J Friston
    The Wellcome Department of Cognitive Neurology, The National Hospital, UK
    Neuroscientist 7:406-18. 2001
    ..The nonlinear nature of asynchronous coupling enables the rich, context-sensitive interactions that characterize real brain dynamics, suggesting that it plays an important role in functional integration...
  33. pmc Nonlinear PCA: characterizing interactions between modes of brain activity
    K Friston
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
    Philos Trans R Soc Lond B Biol Sci 355:135-46. 2000
    ..The examples considered include interactions between cognitive states and time (i.e. adaptation or plasticity in PET data) and among functionally specialized brain systems (using a fMRI study of colour and motion processing)...
  34. pmc The labile brain. II. Transients, complexity and selection
    K J Friston
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
    Philos Trans R Soc Lond B Biol Sci 355:237-52. 2000
    ..In short, the emergence of order, through selection, depends almost paradoxically on the instabilities that characterize the diversity of brain dynamics. The second perspective is provided by information theory...
  35. ncbi request reprint Revealing interactions among brain systems with nonlinear PCA
    K Friston
    The Wellcome Department of Cognitive Neurology, Institute of Neurology, Queen Square, London, UK
    Hum Brain Mapp 8:92-7. 1999
    ..The example considers interactions among functionally specialized brain systems (using a fMRI study of colour and motion processing)...
  36. ncbi request reprint Functional integration and inference in the brain
    Karl Friston
    The Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London, UK
    Prog Neurobiol 68:113-43. 2002
    ..The conclusion of these studies points toward the prevalence of top-down influences and the plausibility of generative models of sensory brain function...
  37. pmc The labile brain. III. Transients and spatio-temporal receptive fields
    K J Friston
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
    Philos Trans R Soc Lond B Biol Sci 355:253-65. 2000
    ....
  38. pmc Attentional modulation of effective connectivity from V2 to V5/MT in humans
    K J Friston
    The Wellcome Department of Cognitive Neurology, 12 Queen Square, London WC1N 3BG, United Kingdom
    Proc Natl Acad Sci U S A 97:7591-6. 2000
    ..These results speak to the context-sensitive nature of functional integration in the brain and provide empirical evidence that attentional effects may be mediated by backwards connections, of a modulatory sort, in humans...
  39. pmc The labile brain. I. Neuronal transients and nonlinear coupling
    K J Friston
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
    Philos Trans R Soc Lond B Biol Sci 355:215-36. 2000
    ..g. cross-correlograms and coherence). Using neuromagnetic data it is shown that nonlinear (asynchronous) coupling is, in fact, more abundant and can be more significant than synchronous coupling...
  40. ncbi request reprint Testing for anatomically specified regional effects
    K J Friston
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London, United Kingdom
    Hum Brain Mapp 5:133-6. 1997
    ..The advantage of the current test is that it eschews a correction for multiple comparisons even though the exact location of the expected activation may not be known...
  41. ncbi request reprint Beyond phrenology: what can neuroimaging tell us about distributed circuitry?
    Karl Friston
    The Wellcome Department of Cognitive Neurology, University College London, Queen Square, United Kingdom
    Annu Rev Neurosci 25:221-50. 2002
    ..The conclusion, from these sorts of neuroimaging studies, points to the prevalence of top-down influences and the plausibility of generative models of sensory brain function...
  42. ncbi request reprint Psychophysiological and modulatory interactions in neuroimaging
    K J Friston
    Wellcome Department of Cognitive Neurology, London, United Kingdom
    Neuroimage 6:218-29. 1997
    ..We focus on interactions among extrastriate, inferotemporal, and posterior parietal regions during visual processing, under different attentional and perceptual conditions...
  43. pmc Imaging neuroscience: principles or maps?
    K J Friston
    The Wellcome Department of Cognitive Neurology, Institute of Neurology, London WC1N 3BG, United Kingdom
    Proc Natl Acad Sci U S A 95:796-802. 1998
    ....
  44. ncbi request reprint The disconnection hypothesis
    K J Friston
    Wellcome Department of Cognitive Neurology, Institute of Neurology, Queen Square, London, UK
    Schizophr Res 30:115-25. 1998
    ..The proposed pathophysiology would translate, in functional terms, into a disruption of the reinforcement of adaptive behaviour that is consistent with the disintegrative aspects of schizophrenic neuropsychology...
  45. ncbi request reprint Generative models, brain function and neuroimaging
    K J Friston
    The Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
    Scand J Psychol 42:167-77. 2001
    ..Here we focus on the implications for cognitive neuroscience in the context of neuroimaging...
  46. ncbi request reprint Multivariate autoregressive modeling of fMRI time series
    L Harrison
    Wellcome Department of Imaging Neuroscience, University College London, 12 Queen Square, London WC1N 3BG, UK
    Neuroimage 19:1477-91. 2003
    ..A further benefit of the MAR approach is that connectivity maps may contain loops, yet exact inference can proceed within a linear framework. Model order selection and parameter estimation are implemented by using Bayesian methods...
  47. ncbi request reprint Dynamic causal modeling of evoked responses in EEG and MEG
    Olivier David
    Wellcome Department of Imaging Neuroscience, Functional Imaging Laboratory, Institute of Neurology, UCL, 12 Queen Square, London WC1N 3BG, UK
    Neuroimage 30:1255-72. 2006
    ..These examples show that category- or context-specific coupling among cortical regions can be assessed explicitly, within a mechanistic, biologically motivated inference framework...
  48. ncbi request reprint Modelling event-related responses in the brain
    Olivier David
    Wellcome Department of Imaging Neuroscience, Functional Imaging Laboratory, 12 Queen Square, London WC1N 3BG, UK
    Neuroimage 25:756-70. 2005
    ..This interaction is expressed as a phase-resetting and represents a qualitatively different explanation for the ERP/ERF...
  49. pmc Repetition suppression and plasticity in the human brain
    Marta I Garrido
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, UK
    Neuroimage 48:269-79. 2009
    ..It is remarkable that distinct changes in intrinsic and extrinsic connections could be quantified so reliably and non-invasively using EEG...
  50. pmc Integrated Bayesian models of learning and decision making for saccadic eye movements
    Kay H Brodersen
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
    Neural Netw 21:1247-60. 2008
    ....
  51. pmc Nonlinear coupling in the human motor system
    Chun Chuan Chen
    Wellcome Trust Centre for Neuroimaging, University College London, London, UK ucl ac uk
    J Neurosci 30:8393-9. 2010
    ..Our results provide empirical evidence for nonlinear coupling among distributed neuronal sources in the motor system and that these play an important role in modulating spectral responses under normal conditions...
  52. ncbi request reprint Modeling geometric deformations in EPI time series
    J L Andersson
    The Wellcome Department of Cognitive Neurology, London, United Kingdom
    Neuroimage 13:903-19. 2001
    ..An experiment on a subject performing voluntary movements in the scanner yielded plausible estimates of the deformation fields and their application to "unwarp" the time series significantly reduced movement-related variance...
  53. ncbi request reprint Cholinergic modulation of experience-dependent plasticity in human auditory cortex
    Christiane M Thiel
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, 12 Queen Square, London WC1 3BG, United Kingdom
    Neuron 35:567-74. 2002
    ..This study provides in vivo evidence that experience-dependent plasticity, evident in hemodynamic changes in human auditory cortex, is modulated by acetylcholine...
  54. ncbi request reprint Estimating efficiency a priori: a comparison of blocked and randomized designs
    Andrea Mechelli
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, 12 Queen Square, London, WC1N 3BG, UK
    Neuroimage 18:798-805. 2003
    ..Furthermore, we show that the error variance can change with the experimental design. This highlights a problem with a priori comparison of efficiency for two or more experimental designs, which usually assumes identical error variance...
  55. pmc Bilinear dynamical systems
    W Penny
    Wellcome Department of Imaging Neuroscience, University College, London WC1N 3BG, UK
    Philos Trans R Soc Lond B Biol Sci 360:983-93. 2005
    ..We report preliminary results that focus on the assumed stochastic nature of the neurodynamic model and compare the method to Wiener deconvolution...
  56. ncbi request reprint Mechanisms of evoked and induced responses in MEG/EEG
    Olivier David
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, 12 Queen Square, London WC1N 3BG, UK
    Neuroimage 31:1580-91. 2006
    ..We introduce adjusted power to complement induced power. Adjusted power is unaffected by trial-to-trial variations in input and can be attributed to structural perturbations without ambiguity...
  57. pmc The mismatch negativity: a review of underlying mechanisms
    Marta I Garrido
    Wellcome Trust Centre for Neuroimaging, University College London, UK
    Clin Neurophysiol 120:453-63. 2009
    ..This paper presents a review of studies that focus on neuronal mechanisms underlying the MMN generation, discusses the two major explanatory hypotheses, and proposes predictive coding as a general framework that attempts to unify both...
  58. ncbi request reprint A multimodal language region in the ventral visual pathway
    C Buchel
    The Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
    Nature 394:274-7. 1998
    ..Our study confirms a prediction of theories of brain function that depend on convergence zones; the absence of one input (that is, visual) does not alter the response properties of such a convergence region...
  59. ncbi request reprint A global estimator unbiased by local changes
    J L Andersson
    The Wellcome Department of Cognitive Neurology, London, United Kingdom
    Neuroimage 13:1193-206. 2001
    ..The advantage of the new estimator is that it is not informed of experimental design and relies only on general assumptions regarding the nature of the signal...
  60. pmc Dynamic Causal Models for phase coupling
    W D Penny
    Wellcome Trust Centre for Neuroimaging, University College, 12 Queen Square, London WC1N 3BG, UK
    J Neurosci Methods 183:19-30. 2009
    ..For example, whether activity is driven by master-slave versus mutual entrainment mechanisms. Results are presented on synthetic data from physiological models and on MEG data from a study of visual working memory...
  61. pmc Topological FDR for neuroimaging
    J Chumbley
    Wellcome Trust Centre for Neuroimaging, London, UK
    Neuroimage 49:3057-64. 2010
    ..Finally, we present an illustrative application using an fMRI study of visual attention...
  62. ncbi request reprint Identification of degenerate neuronal systems based on intersubject variability
    Uta Noppeney
    Wellcome Department of Imaging Neuroscience, University College London, 12 Queen Square, WC1 N3BG London, UK
    Neuroimage 30:885-90. 2006
    ..These results suggest that semantic decisions on auditory-visual compound stimuli might be accomplished by two overlapping degenerate neuronal systems...
  63. pmc Post-hoc selection of dynamic causal models
    M J Rosa
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, WC1N 3BG, UK
    J Neurosci Methods 208:66-78. 2012
    ....
  64. ncbi request reprint Identifying global anatomical differences: deformation-based morphometry
    J Ashburner
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
    Hum Brain Mapp 6:348-57. 1998
    ..To illustrate the method, we compared the gross morphometry of male and female subjects. We also assessed brain asymmetry, the effect of handedness, and interactions among these effects...
  65. ncbi request reprint Conjunction revisited
    Karl J Friston
    The Wellcome Department of Imaging Neuroscience and Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London, WC1N 3AR, UK
    Neuroimage 25:661-7. 2005
    ..This more general conjunction test is described...
  66. ncbi request reprint Activation in posterior superior temporal sulcus parallels parameter inducing the percept of animacy
    Johannes Schultz
    Wellcome Department of Imaging Neuroscience, 12 Queen Square, London WC1N 3BG, United Kingdom
    Neuron 45:625-35. 2005
    ....
  67. pmc The functional anatomy of the MMN: a DCM study of the roving paradigm
    Marta I Garrido
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, UK
    Neuroimage 42:936-44. 2008
    ..Ilmoniemi, R.J., Levänen, S., Lin, F.H., May, P., Melcher, J., Stufflebeam, S., Tiitinen, H., Belliveau, J.W., 2004. Human posterior auditory cortex gates novel sounds to consciousness. Proc. Natl. Acad. Sci. U. S. A. 101, 6809-6814]...
  68. ncbi request reprint Signal-, set- and movement-related activity in the human brain: an event-related fMRI study
    I Toni
    Wellcome Department of Cognitive Neurology, Institute of Neurology, University of Oxford, UK
    Cereb Cortex 9:35-49. 1999
    ..Rather, these processes seem to rely on the ventral visual stream, the ventral prefrontal cortex and the anterior part of the dorsal premotor cortex...
  69. ncbi request reprint Learning-related neuronal responses in prefrontal cortex studied with functional neuroimaging
    P Fletcher
    The Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
    Cereb Cortex 9:168-78. 1999
    ..We interpret our findings in terms of a left frontal system mediating the semantic analysis of study items and directly influencing a right fronto-parietal system associated with episodic memory retrieval...
  70. doi request reprint Short-term adaptation to a simple motor task: a physiological process preserved in multiple sclerosis
    L Mancini
    Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK
    Neuroimage 45:500-11. 2009
    ..These findings confirm that the short-term adaptation to a simple motor task is a physiological process which is preserved in MS...
  71. pmc A dual role for prediction error in associative learning
    Hanneke E M den Ouden
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
    Cereb Cortex 19:1175-85. 2009
    ..These results posit a dual role for prediction-error in encoding surprise and driving associative plasticity...
  72. pmc Bayesian model selection for group studies
    Klaas Enno Stephan
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, UK
    Neuroimage 46:1004-17. 2009
    ..g. comparing different source reconstruction methods for EEG/MEG or selecting among competing computational models of learning and decision-making...
  73. ncbi request reprint Design and analysis of fMRI studies with neurologically impaired patients
    Cathy J Price
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, London, United Kingdom
    J Magn Reson Imaging 23:816-26. 2006
    ..In contrast, deficits in functional integration are implied when the influence of one brain region on another is stronger or weaker in patients relative to control subjects...
  74. pmc A hierarchy of time-scales and the brain
    Stefan J Kiebel
    Wellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom
    PLoS Comput Biol 4:e1000209. 2008
    ..The framework provides predictions about, and principled constraints on, cortical structure-function relationships, which can be tested by manipulating the time-scales of sensory input...
  75. pmc The cortical dynamics of intelligible speech
    Alexander P Leff
    Wellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom
    J Neurosci 28:13209-15. 2008
    ..Task-related, directional effects can now be incorporated into models of speech comprehension...
  76. pmc Influence of uncertainty and surprise on human corticospinal excitability during preparation for action
    Sven Bestmann
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, UK
    Curr Biol 18:775-80. 2008
    ..Commensurate effects were observed in reaction times. We suggest that motor output is biased according to contextual probabilities that are represented dynamically in the brain...
  77. pmc Evidence of mirror neurons in human inferior frontal gyrus
    James M Kilner
    The Wellcome Trust Centre for Neuroimaging, Institute of Neurology, UCL, London, United Kingdom
    J Neurosci 29:10153-9. 2009
    ..This pattern of responses is consistent with that predicted by mirror neurons and is evidence of mirror neurons in the human IFG...
  78. doi request reprint Computing average shaped tissue probability templates
    John Ashburner
    Wellcome Trust Centre for Neuroimaging, 12 Queen Square, London, WC1N 3BG, UK
    Neuroimage 45:333-41. 2009
    ..g. grey and white matter) are registered simultaneously with the current template estimate. In order to generalise the resulting template to a broader range of subjects, a template blurriness prior is included within the model...
  79. pmc Recognizing sequences of sequences
    Stefan J Kiebel
    Wellcome Trust Centre for Neuroimaging, London, UK
    PLoS Comput Biol 5:e1000464. 2009
    ..By presenting anomalous stimuli, we find that the resulting recognition dynamics disclose inference at multiple time scales and are reminiscent of neuronal dynamics seen in the real brain...
  80. pmc Time-series analysis for rapid event-related skin conductance responses
    Dominik R Bach
    Wellcome Trust Centre for Neuroimaging, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom
    J Neurosci Methods 184:224-34. 2009
    ..We suggest our approach provides greater flexibility in analysing SCRs than existing methods...
  81. pmc Optimized beamforming for simultaneous MEG and intracranial local field potential recordings in deep brain stimulation patients
    Vladimir Litvak
    UCL Institute of Neurology, Queen Square, WC1N 3BG, London, UK
    Neuroimage 50:1578-88. 2010
    ..Our findings demonstrate that physiologically meaningful information can be extracted from heavily contaminated MEG signals and pave the way for further analysis of combined MEG-LFP recordings in DBS patients...
  82. pmc Modelling event-related skin conductance responses
    Dominik R Bach
    Wellcome Trust Centre for Neuroimaging, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom
    Int J Psychophysiol 75:349-56. 2010
    ..We develop a canonical response function and show that it can be used for signals from different recording sites. We discuss the implications of these observations for model-based analysis of SCRs...
  83. pmc Dynamic causal modelling of distributed electromagnetic responses
    Jean Daunizeau
    The Wellcome Trust Centre for Neuroimaging, Institute of Neurology, UCL 12 Queen Square, London, WC1N 3BG UK
    Neuroimage 47:590-601. 2009
    ..Here, we describe the distributed spatial model and present a comparative evaluation with conventional equivalent current dipole (ECD) models of auditory processing, as measured with EEG...
  84. pmc A dynamic causal model study of neuronal population dynamics
    André C Marreiros
    The Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, UCL, 12 Queen Square, London, UK WC1N 3BG, UK
    Neuroimage 51:91-101. 2010
    ....
  85. doi request reprint Dynamic causal modeling for EEG and MEG
    Stefan J Kiebel
    The Wellcome Trust Centre for Neuroimaging, University College London, 12 Queen Square, London, United Kingdom
    Hum Brain Mapp 30:1866-76. 2009
    ..We suggest that DCM and Bayesian model comparison provides a useful way to test hypotheses about distributed processing in the brain, using electromagnetic data...
  86. pmc Analytic measures for quantification of arousal from spontaneous skin conductance fluctuations
    Dominik R Bach
    Wellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom
    Int J Psychophysiol 76:52-5. 2010
    ..We demonstrate the validity of this measure in relation to finite impulse response models, and show that it is a better predictor of autonomic arousal, relative to conventional measures...
  87. pmc Observing the observer (I): meta-bayesian models of learning and decision-making
    Jean Daunizeau
    Wellcome Trust Centre for Neuroimaging, University College of London, London, United Kingdom
    PLoS ONE 5:e15554. 2010
    ....
  88. ncbi request reprint Anatomically informed basis functions in multisubject studies
    Stefan Kiebel
    The Wellcome Department of Imaging Neuroscience, The Institute of Neurology, 12 Queen Square, WC1N 3BG London, United Kingdom
    Hum Brain Mapp 16:36-46. 2002
    ..It is shown that this procedure offers various advantages compared to existing conventional methods for the analysis of multisubject studies, in particular it is more sensitive to underlying activations...
  89. pmc Evoked brain responses are generated by feedback loops
    Marta I Garrido
    Wellcome Trust Centre for Neuroimaging, University College London, London WC1N 3BG, United Kingdom
    Proc Natl Acad Sci U S A 104:20961-6. 2007
    ..This is the theoretical cornerstone of most modern theories of perceptual inference and learning...
  90. ncbi request reprint Functional magnetic resonance imaging of human absence seizures
    Afraim Salek-Haddadi
    Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London
    Ann Neurol 53:663-7. 2003
    ..We demonstrate the reciprocal participation of focal thalamic and widespread cortical networks during human absence seizures and suggest reductions in cortical blood flow, in response to synchronized electroencephalogram activity...
  91. ncbi request reprint Dissociating reading processes on the basis of neuronal interactions
    Andrea Mechelli
    Functional Imaging Laboratory, Wellcome Department of Imaging Neuroscience, Institute of Neurology, London, UK
    J Cogn Neurosci 17:1753-65. 2005
    ..The present investigation is the first to identify distinct neuronal mechanisms for semantic and phonological contributions to reading...
  92. ncbi request reprint Structural covariance in the human cortex
    Andrea Mechelli
    Wellcome Department of Imaging Neuroscience, London WC1N 3BG, United Kingdom
    J Neurosci 25:8303-10. 2005
    ..The coordinated variations we report are likely to be determined by both genetic and environmental factors and may be the basis for differences in individual behavior...
  93. ncbi request reprint Unified segmentation
    John Ashburner
    Wellcome Department of Imaging Neuroscience, 12 Queen Square, London, WC1N 3BG, UK
    Neuroimage 26:839-51. 2005
    ..A strategy for optimising the model parameters is described, along with the requisite partial derivatives of the objective function...
  94. ncbi request reprint Functional imaging studies of neuropsychological patients: applications and limitations
    Cathy J Price
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    Neurocase 8:345-54. 2002
    ..This, in turn, has important implications for understanding the mechanisms that mediate recovery and the organizational principles that underlie functional architectures in the human brain...
  95. ncbi request reprint Effective connectivity and intersubject variability: using a multisubject network to test differences and commonalities
    Andrea Mechelli
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, 12 Queen Square, London, WCIN 3BG, United Kingdom
    Neuroimage 17:1459-69. 2002
    ..The discussion focuses on the implications of our findings and on further applications of the multisubject network analysis...
  96. ncbi request reprint Parametric analysis of oscillatory activity as measured with EEG/MEG
    Stefan J Kiebel
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, London, United Kingdom
    Hum Brain Mapp 26:170-7. 2005
    ..We establish the validity of parametric tests using synthetic and real data and compare its performance to established nonparametric procedures...
  97. ncbi request reprint Information theory, novelty and hippocampal responses: unpredicted or unpredictable?
    Bryan A Strange
    Wellcome Department of Imaging Neuroscience, Functional Imaging Laboratory, Institute of Neurology, 12 Queen Square, London WC1N 3BG, UK
    Neural Netw 18:225-30. 2005
    ..In short, we show that the probabilistic structure or context in which events occur is an important predictor of hippocampal activity...
  98. ncbi request reprint Frequency specific changes in regional cerebral blood flow and motor system connectivity following rTMS to the primary motor cortex
    Elisabeth Rounis
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, UK
    Neuroimage 26:164-76. 2005
    ..J. Neurosci. 23, 5308-5318.) by providing evidence that the pattern of acute reorganization in the motor network following rTMS depends on the direction of conditioning...
  99. ncbi request reprint Applications of random field theory to electrophysiology
    James M Kilner
    The Wellcome Department of Imaging Neuroscience, Institute of Neurology, 12 Queen Square, London WC1N 3BG, UK
    Neurosci Lett 374:174-8. 2005
    ..Here, by analysing the time-frequency decompositions of single channel EEG data we show that RFT adjustments can be used in the analysis of electrophysiological data and illustrate the advantages of this method over existing approaches...
  100. ncbi request reprint Bayesian fMRI time series analysis with spatial priors
    William D Penny
    Wellcome Department of Imaging Neuroscience, UCL, London, UK
    Neuroimage 24:350-62. 2005
    ..Our model generalizes earlier work on voxel-wise estimation of GLM-AR models and inference in GLMs using Posterior Probability Maps (PPMs). Results are shown on simulated data and on data from an event-related fMRI experiment...
  101. pmc Encoding of marginal utility across time in the human brain
    Alex Pine
    Wellcome Trust Centre for Neuroimaging, London, United Kingdom
    J Neurosci 29:9575-81. 2009
    ..Our data support an integrative architecture for decision making, revealing the neural representation of distinct subcomponents of value that may contribute to impulsivity and decisiveness...