Alex A Freitas

Summary

Affiliation: University of Kent
Country: UK

Publications

  1. pmc GPCRTree: online hierarchical classification of GPCR function
    Matthew N Davies
    The Jenner Institute, University of Oxford, Compton, Newbury, Berkshire, RG20 7NN, UK
    BMC Res Notes 1:67. 2008
  2. doi request reprint On the importance of comprehensible classification models for protein function prediction
    Alex A Freitas
    Computing Laboratory, University of Kent, Canterbury, UK
    IEEE/ACM Trans Comput Biol Bioinform 7:172-82. 2010
  3. doi request reprint A review and appraisal of the DNA damage theory of ageing
    Alex A Freitas
    University of Liverpool, Liverpool, UK
    Mutat Res 728:12-22. 2011
  4. pmc A data mining approach for classifying DNA repair genes into ageing-related or non-ageing-related
    Alex A Freitas
    Integrative Genomics of Ageing Group, Institute of Integrative Biology, University of Liverpool, Biosciences Building, Crown Street, Liverpool, L69 7ZB, UK
    BMC Genomics 12:27. 2011
  5. doi request reprint Message-passing algorithms for the prediction of protein domain interactions from protein-protein interaction data
    Mudassar Iqbal
    Computing Laboratory and Centre for BioMedical Informatics, University of Kent, Canterbury, UK
    Bioinformatics 24:2064-70. 2008
  6. ncbi request reprint Predicting post-synaptic activity in proteins with data mining
    Gisele L Pappa
    Computing Laboratory, University of Kent, Canterbury, UK
    Bioinformatics 21:ii19-25. 2005

Collaborators

Detail Information

Publications6

  1. pmc GPCRTree: online hierarchical classification of GPCR function
    Matthew N Davies
    The Jenner Institute, University of Oxford, Compton, Newbury, Berkshire, RG20 7NN, UK
    BMC Res Notes 1:67. 2008
    ..Approximately 50% of all marketed drugs target a GPCR. There remains considerable interest in effectively predicting the function of a GPCR from its primary sequence...
  2. doi request reprint On the importance of comprehensible classification models for protein function prediction
    Alex A Freitas
    Computing Laboratory, University of Kent, Canterbury, UK
    IEEE/ACM Trans Comput Biol Bioinform 7:172-82. 2010
    ..Second, it presents a critical review of the pros and cons of several different knowledge representations that can be used in order to support the discovery of comprehensible protein function prediction models...
  3. doi request reprint A review and appraisal of the DNA damage theory of ageing
    Alex A Freitas
    University of Liverpool, Liverpool, UK
    Mutat Res 728:12-22. 2011
    ....
  4. pmc A data mining approach for classifying DNA repair genes into ageing-related or non-ageing-related
    Alex A Freitas
    Integrative Genomics of Ageing Group, Institute of Integrative Biology, University of Liverpool, Biosciences Building, Crown Street, Liverpool, L69 7ZB, UK
    BMC Genomics 12:27. 2011
    ..The goal is to build classification models that allow us to discriminate between ageing-related and non-ageing-related DNA repair genes, in order to better understand their different properties...
  5. doi request reprint Message-passing algorithms for the prediction of protein domain interactions from protein-protein interaction data
    Mudassar Iqbal
    Computing Laboratory and Centre for BioMedical Informatics, University of Kent, Canterbury, UK
    Bioinformatics 24:2064-70. 2008
    ..This noise leads to contradictions, i.e. the impossibility of having a pattern of domain interactions compatible with the protein-protein interaction map...
  6. ncbi request reprint Predicting post-synaptic activity in proteins with data mining
    Gisele L Pappa
    Computing Laboratory, University of Kent, Canterbury, UK
    Bioinformatics 21:ii19-25. 2005
    ..The discovered rules were analysed with respect to their predictive accuracy (generalization ability) and with respect to their interestingness to biologists (in the sense of representing novel, unexpected knowledge)...