Ruth Bridget Ferns
Affiliation: University College London
- Quantitation of hepatitis delta virus using a single-step internally controlled real-time RT-qPCR and a full-length genomic RNA calibration standardR B Ferns
Research Department of Infection, Division of Infection and Immunity, University College London, London, UK
J Virol Methods 179:189-94. 2012..4×10(4) to 4.4×10(8) copies/ml. The assay described provides a reliable and sensitive quantitative system for therapeutic monitoring and for studying the dynamic interplay between hepatitis B virus replication and HDV viral load...
- The prospective evaluation of a nested polymerase chain reaction assay for the early detection of Aspergillus infection in patients with leukaemia or undergoing allograft treatmentR Bridget Ferns
Department of Virology, Royal Free and University College Medical School, Windeyer Institute of Medical Sciences, London, UK
Br J Haematol 119:720-5. 2002..In summary, six of seven patients thought to have clinical evidence of infection were PCR positive on at least one occasion and treatment with antifungals may have reduced infection below detectable levels...
- Evaluation of the role of real-time PCR in the diagnosis of invasive aspergillosisR B Ferns
Royal Free and University College Medical School, University College London, Division of Infection and Immunity, Department of Infection, Centre of Virology, London, UK
Leuk Lymphoma 47:15-20. 2006..The effect of anti-fungal treatment is noted. The requirement for both international standards and a consensus protocol that is sensitive enough for IA diagnosis, particularly in blood, is discussed...
- Presence of hepatitis B virus core promoter mutations pre-seroconversion predict persistent viral replication after HBeAg lossR Bridget Ferns
Centre for Virology, Department of Infection, University College, Windeyer Building, 46 Cleveland Street, London W1T 4JF, United Kingdom
J Clin Virol 39:199-204. 2007..In patients with chronic hepatitis B virus (HBV) infection DNA levels do not always fall after anti-hepatitis B e (anti-HBe) seroconversion...
- The dynamics of appearance and disappearance of HIV-1 integrase mutations during and after withdrawal of raltegravir therapyRuth Bridget Ferns
Division of Infection and Immunity, University College London, London, UK
AIDS 23:2159-64. 2009..To monitor HIV-1 integrase resistance mutations during raltegravir (RAL) therapy, including the impact of RAL interruption...
- A 'first loop' linear epitope accessible on native hepatitis B surface antigen that persists in the face of 'second loop' immune escapeSamreen Ijaz
Department of Virology, Royal Free and University College Medical School, Windeyer Building, 46 Cleveland Street, London W1T 4JF, UK
J Gen Virol 84:269-75. 2003..The mAb and its binding region in the first loop are important diagnostically and may represent an importance immunological target, one that is stable in the face of immunologically driven escape...
- A low rate of hepatitis B virus vaccine breakthrough infections in MongoliaSamreen Ijaz
Department of Virology, Royal Free and University College Medical School, London, United Kingdom
J Med Virol 78:1554-9. 2006..However, continued surveillance of breakthrough infections and close monitoring of "vaccine escape" mutants is required...