Andy Fenton

Summary

Affiliation: University of Liverpool
Country: UK

Publications

  1. ncbi request reprint Host availability and the evolution of parasite life-history strategies
    Jenny Crossan
    School of Biological Sciences, University of Liverpool, Biosciences Building, Crown Street, Liverpool, L69 7ZB, United Kingdom
    Evolution 61:675-84. 2007
  2. pmc Dances with worms: the ecological and evolutionary impacts of deworming on coinfecting pathogens
    Andy Fenton
    Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK
    Parasitology 140:1119-32. 2013
  3. doi request reprint Two-step infection processes can lead to coevolution between functionally independent infection and resistance pathways
    Andy Fenton
    Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom
    Evolution 66:2030-41. 2012
  4. pmc The impact of phages on interspecific competition in experimental populations of bacteria
    Michael A Brockhurst
    Department of Plant Sciences, University of Oxford, Oxford, OX1 3RB, UK
    BMC Ecol 6:19. 2006
  5. ncbi request reprint Plasma level of platelet-derived microparticles is associated with coronary heart disease risk score in healthy men
    Tetsuya Ueba
    Department of Neurosurgery, Kishiwada City Hospital, Osaka, Japan
    J Atheroscler Thromb 17:342-9. 2010
  6. doi request reprint Optimality analysis of Th1/Th2 immune responses during microparasite-macroparasite co-infection, with epidemiological feedbacks
    Andy Fenton
    School of Biological Sciences, University of Liverpool, Biosciences Building, Crown Street, Liverpool, L69 7ZB, UK
    Parasitology 135:841-53. 2008
  7. doi request reprint Detecting interspecific macroparasite interactions from ecological data: patterns and process
    Andy Fenton
    School of Biological Sciences, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK
    Ecol Lett 13:606-15. 2010
  8. ncbi request reprint A SNP of NPC1L1 affects cholesterol absorption in Japanese
    Tomomi Maeda
    Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan
    J Atheroscler Thromb 17:356-60. 2010
  9. ncbi request reprint Adipose tissue, inflammation and atherosclerosis
    Birgit Gustafson
    The Lundberg Laboratory for Diabetes Research, Center of Excellence for Metabolic and Cardiovascular Research, Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden
    J Atheroscler Thromb 17:332-41. 2010
  10. doi request reprint Applying predator-prey theory to modelling immune-mediated, within-host interspecific parasite interactions
    Andy Fenton
    School of Biological Sciences, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK
    Parasitology 137:1027-38. 2010

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Host availability and the evolution of parasite life-history strategies
    Jenny Crossan
    School of Biological Sciences, University of Liverpool, Biosciences Building, Crown Street, Liverpool, L69 7ZB, United Kingdom
    Evolution 61:675-84. 2007
    ..Incorporating parasite evolution in response to host availability would therefore enhance the predictive ability of current epidemiological models of infectious disease...
  2. pmc Dances with worms: the ecological and evolutionary impacts of deworming on coinfecting pathogens
    Andy Fenton
    Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK
    Parasitology 140:1119-32. 2013
    ..However, despite this complexity, this framework reveals predictable patterns in the effects of helminths that may aid the development of more effective, integrated management strategies to combat pathogens in this coinfected world...
  3. doi request reprint Two-step infection processes can lead to coevolution between functionally independent infection and resistance pathways
    Andy Fenton
    Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom
    Evolution 66:2030-41. 2012
    ..Such multistep infection processes are a fundamental, but overlooked feature of many host-pathogen interactions, and have important consequences for our understanding of host-pathogen coevolution...
  4. pmc The impact of phages on interspecific competition in experimental populations of bacteria
    Michael A Brockhurst
    Department of Plant Sciences, University of Oxford, Oxford, OX1 3RB, UK
    BMC Ecol 6:19. 2006
    ..Communities were propagated at two environmental temperatures that reversed the outcome of competition in the absence of phage...
  5. ncbi request reprint Plasma level of platelet-derived microparticles is associated with coronary heart disease risk score in healthy men
    Tetsuya Ueba
    Department of Neurosurgery, Kishiwada City Hospital, Osaka, Japan
    J Atheroscler Thromb 17:342-9. 2010
    ..The aim of this study was to clarify the relationship between platelet-derived microparticles (PDMPs) and the Framingham 10-yr coronary heart disease (CHD) risk score...
  6. doi request reprint Optimality analysis of Th1/Th2 immune responses during microparasite-macroparasite co-infection, with epidemiological feedbacks
    Andy Fenton
    School of Biological Sciences, University of Liverpool, Biosciences Building, Crown Street, Liverpool, L69 7ZB, UK
    Parasitology 135:841-53. 2008
    ....
  7. doi request reprint Detecting interspecific macroparasite interactions from ecological data: patterns and process
    Andy Fenton
    School of Biological Sciences, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK
    Ecol Lett 13:606-15. 2010
    ..However, application of the GLMM approach may provide a more robust method of detection for these potentially important interspecific interactions from ecological data...
  8. ncbi request reprint A SNP of NPC1L1 affects cholesterol absorption in Japanese
    Tomomi Maeda
    Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan
    J Atheroscler Thromb 17:356-60. 2010
    ..The response of serum LDL-C levels to ezetimibe was reported to differe among NPC1L1 haplotypes.We analyzed NPC1L1 genotypes in Japanese and investigated differences in markers of cholesterol synthesis/absorption among the genotypes...
  9. ncbi request reprint Adipose tissue, inflammation and atherosclerosis
    Birgit Gustafson
    The Lundberg Laboratory for Diabetes Research, Center of Excellence for Metabolic and Cardiovascular Research, Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden
    J Atheroscler Thromb 17:332-41. 2010
    ..The underlying mechanisms of ectopic fat accumulation in various tissues and the impact on metabolic syndrome and its association with insulin resistance are discussed...
  10. doi request reprint Applying predator-prey theory to modelling immune-mediated, within-host interspecific parasite interactions
    Andy Fenton
    School of Biological Sciences, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK
    Parasitology 137:1027-38. 2010
    ..We urge for more detailed empirical information relating immune activity to parasite load to enable better predictions of the dynamic consequences of immune-mediated interspecific interactions within parasite communities...
  11. ncbi request reprint What psychosocial characteristics are associated with smoking cessation behavior and readiness to quit smoking among Japanese male ever-smokers with type 2 diabetes mellitus?
    Akiko Morimoto
    Department of Clinical Nursing, Shiga University of Medical Science, Shiga, Japan
    J Atheroscler Thromb 17:361-8. 2010
    ..The relationship between psychosocial characteristics and smoking cessation behavior was examined among Japanese male eversmokers with type 2 diabetes mellitus...
  12. ncbi request reprint Worms and germs: the population dynamic consequences of microparasite-macroparasite co-infection
    Andy Fenton
    School of Biological Sciences, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK
    Parasitology 135:1545-60. 2008
    ....
  13. doi request reprint Solving the Wolbachia paradox: modeling the tripartite interaction between host, Wolbachia, and a natural enemy
    Andrew Fenton
    Institute of Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 7ZB, United Kingdom
    Am Nat 178:333-42. 2011
    ..They also support the intriguing possibility that Wolbachia strains that encode both CI and natural-enemy resistance could potentially rid insects, including human disease vectors, of important pathogens...
  14. pmc Community epidemiology framework for classifying disease threats
    Andy Fenton
    Institute of Zoology, London, United Kingdom
    Emerg Infect Dis 11:1815-21. 2005
    ....
  15. ncbi request reprint The impact of parasite manipulation and predator foraging behavior on predator-prey communities
    A Fenton
    School of Biological Sciences, Crown Street, University of Liverpool, Liverpool L69 7ZB, UK
    Ecology 87:2832-41. 2006
    ....
  16. pmc Pathogen responses to host immunity: the impact of time delays and memory on the evolution of virulence
    A Fenton
    Institute of Zoology, Zoological Society of London, Regents Park, London NW1 4RY, UK
    Proc Biol Sci 273:2083-90. 2006
    ..Furthermore, we use this model to show how distributed primary immune responses combine with immune memory to greatly affect the optimal virulence of the pathogen, potentially resulting in the evolution of highly virulent pathogens...
  17. doi request reprint Dispersal and natural enemies interact to drive spatial synchrony and decrease stability in patchy populations
    Tom Vogwill
    School of Biological Sciences, University of Liverpool, Liverpool, UK
    Ecol Lett 12:1194-200. 2009
    ..Taken together, our findings suggest that dispersal and natural enemies can interact to drive spatially synchronous population fluctuations that decrease stability at both the patch and population level...
  18. pmc Coevolving parasites enhance the diversity-decreasing effect of dispersal
    Tom Vogwill
    Institute of Integrative Biology, University of Liverpool, Biosciences Building, Liverpool L69 7ZB, UK
    Biol Lett 7:578-80. 2011
    ..Thus, our results suggest that, while parasites can drive host diversification, host populations coevolving with parasites are more prone to homogenization through dispersal...
  19. pmc Stability of within-host-parasite communities in a wild mammal system
    Sarah C L Knowles
    Institute of Evolutionary Biology, and Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK
    Proc Biol Sci 280:20130598. 2013
    ....
  20. pmc Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population
    Sarah C L Knowles
    Centre for Immunity, Infection and Evolution CIIE, Institute of Evolutionary Biology, School of Biological Sciences, The University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK
    J Gen Virol 93:2447-56. 2012
    ..They also suggest that gammaherpesvirus infection may have significant detrimental effects in wild hosts, questioning the view that these viruses have limited impacts in natural, co-evolved host species...
  21. doi request reprint How does spatial dispersal network affect the evolution of parasite local adaptation?
    Tom Vogwill
    School of Biological Sciences, University of Liverpool, Biosciences Building, Crown Street, Liverpool, L69 7ZB, United Kingdom
    Evolution 64:1795-801. 2010
    ....
  22. doi request reprint Source populations act as coevolutionary pacemakers in experimental selection mosaics containing hotspots and coldspots
    Tom Vogwill
    School of Biological Sciences, University of Liverpool, Crown Street, Liverpool L69 7ZB, United Kingdom
    Am Nat 173:E171-6. 2009
    ..These results confirm theoretical predictions and suggest that source populations can act as coevolutionary "pacemakers" for recipient populations, overriding local conditions...
  23. doi request reprint Prey-dependent mortality rate: a critical parameter in microbial models
    Ewan J A Minter
    Institute of Integrative Biology, Biosciences Building, University of Liverpool, Liverpool, L69 7ZB, UK
    Microb Ecol 62:155-61. 2011
    ..The differences between incorporating variable and constant mortality rate indicate that including a variable rate could substantially improve microbial-based ecological models...
  24. doi request reprint Limiting damage during infection: lessons from infection tolerance for novel therapeutics
    Pedro F Vale
    Centre for Immunity, Infection, and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Biol 12:e1001769. 2014
    ....
  25. pmc Reconsidering the importance of the past in predator-prey models: both numerical and functional responses depend on delayed prey densities
    Jiqiu Li
    Laboratory of Protozoology, KLB07006, College of Life Science, South China Normal University, Guangzhou 510631, People s Republic of China
    Proc Biol Sci 280:20131389. 2013
    ..We therefore present a new approach to explore time-series data and a revised framework for further theoretical studies. ..
  26. doi request reprint Life in cells, hosts, and vectors: parasite evolution across scales
    Nicole Mideo
    Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom
    Infect Genet Evol 13:344-7. 2013
    ..We demonstrate that such interdisciplinary approaches are possible and identify key areas for future progress...
  27. pmc Strain-specific functional and numerical responses are required to evaluate impacts on predator-prey dynamics
    Zhou Yang
    Jiangsu Province Key Laboratory for Biodiversity and Biotechnology, School of Biological Sciences, Nanjing Normal University, Nanjing, Jiangsu, China
    ISME J 7:405-16. 2013
    ....
  28. pmc Epistatic interactions alter dynamics of multilocus gene-for-gene coevolution
    Andy Fenton
    School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom
    PLoS ONE 2:e1156. 2007
    ..Our results demonstrate that the specific forms of interaction between multiple resistance or virulence genes are a crucial determinant of host-parasite coevolutionary dynamics...
  29. doi request reprint Inflamed adipose tissue, insulin resistance and vascular injury
    Christian X Andersson
    The Lundberg Laboratory for Diabetes Research, Center of Excellence for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine Diabetes, The Sahlgrenska Academy at Goteborg University, Sweden
    Diabetes Metab Res Rev 24:595-603. 2008
    ....
  30. ncbi request reprint Inflamed adipose tissue: a culprit underlying the metabolic syndrome and atherosclerosis
    Birgit Gustafson
    The Lundberg Laboratory for Diabetes Research, Center of Excellence for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Sahlgrenska University Hospital, SE 413 45 Goteborg, Sweden
    Arterioscler Thromb Vasc Biol 27:2276-83. 2007
    ..The insulin resistance further supports the proinflammatory state because insulin, by itself, is both antilipolytic and antiinflammatory by antagonizing cytokine-induced activation of STAT signaling...
  31. ncbi request reprint Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes
    Birgit Gustafson
    Lundberg Laboratory for Diabetes Research, Department of Internal Medicine, The Sahlgrenska Academy at Goteborg University, Sahlgrenska University Hospital, Goteborg SE 413 45, Sweden
    J Biol Chem 281:9507-16. 2006
    ..These results provide an explanation as to why obesity and diabetes are associated with both local and systemic inflammation, insulin resistance, and ectopic lipid accumulation...
  32. ncbi request reprint High local concentrations and effects on differentiation implicate interleukin-6 as a paracrine regulator
    Victoria Rotter Sopasakis
    The Lundberg Laboratory for Diabetes Research, Department of Internal Medicine, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Obes Res 12:454-60. 2004
    ..To examine the possibility that interleukin-6 (IL-6) can act as a paracrine regulator in adipose tissue by examining effects on adipogenic genes and measuring interstitial IL-6 concentrations in situ...
  33. pmc Impaired preadipocyte differentiation in human abdominal obesity: role of Wnt, tumor necrosis factor-alpha, and inflammation
    Petter Isakson
    Lundberg Laboratory for Diabetes Research, Center of Excellence for Metabolic and Cardiovascular Research, Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
    Diabetes 58:1550-7. 2009
    ....
  34. ncbi request reprint Emphasizing the ecology in parasite community ecology
    Amy B Pedersen
    Institute of Ecology, University of Georgia, Athens, GA 30605, USA
    Trends Ecol Evol 22:133-9. 2007
    ..We discuss insights offered by this mechanistic approach that will be crucial for predicting the impact on wildlife and human health of disease control measures, climate change or novel parasite species introductions...
  35. ncbi request reprint Helminths as vectors of pathogens in vertebrate hosts: a theoretical approach
    Sarah E Perkins
    Center for Infectious Disease Dynamics, Penn State University, 208 Mueller Laboratory, University Park, PA 16802, USA
    Int J Parasitol 36:887-94. 2006
    ....