R G Feltbower

..We specifically tested the aetiological hypothesis that a factor influencing geographical or temporal heterogeneity of childhood central nervous system (CNS) tumour incidence was related to exposure to a transient environmental agent...

..There is a paucity of recent epidemiological data on bone cancers. The aim of this study was to describe incidence and survival patterns for bone cancers diagnosed during 1981 - 2002...

..However, between disciplines protocols define different assessment and management in GCT. We aimed to document changes in incidence, treatment, and survival since 1990, to record the baseline to which future trends can be compared...

..We aimed to describe and contrast the epidemiology of haematological malignancies among 0-14 and 15-24-year-olds in northern England from 1990 to 2002 and compare clinical trial entry by age group...

..To examine mortality rates and causes of death among subjects diagnosed with type 1 diabetes aged <or=29 years...

..This provides a baseline for future comparisons and demonstrates that relapsed childhood cancer need not imply a poor outcome...

..Whether reintegration had occurred was assessed using geographic mobility as an objective proxy. Age, sex, and socioeconomic status were identified as being independently associated with mobility whereas diagnosis and relapse were not...

..04). Our timely study shows patterns of occurrence of childhood cancer that differ with respect to ethnic group. Differences are particularly apparent in the excess of AML and incidence peak in 5-9 year olds in south Asian children...

..This study examines incidence rate trends of childhood Type 1 diabetes in Yorkshire 1978-2007, focusing on differences between south Asians and non-south Asians...

..It is unclear whether these differences exist exclusively in the older adult population or whether they begin to emerge in children and young adults...

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..The guidance places the responsibility for implementation and funding of this scheme onto the PCTs...

..Each PCT will expect three to five newly diagnosed children per year. A single GP is likely to see an incident case once every 20 years...

..This overall pattern is consistent with the influence of an environmental agent that is gradually affecting children at younger and younger ages...

..CONCLUSIONS: Following cancer treatment in childhood and adolescence, attendance at long term follow up programmes is determined by social factors including education, employment, and deprivation...

..To provide a population-based clinical audit of children and young people with diabetes, reporting outcomes, including glycaemic control, for named individual units...

..Few studies have examined epidemiological differences between ethnic groups for children and young adults with cancer...

..Improved survival from all cancers in young adults over the last decade is clearly seen. Reasons for differential survival by geographical area are unclear and warrant further investigation...

..Overall, type 2 diabetes is seen more commonly in south Asians, and an association with deprivation is suggested...

..There was a significant positive correlation between diseases. Markers of wealth and affluence were significantly associated with high incidence...

..The absence of any increase in incidence over the last decade contrasts with other paediatric immune mediated conditions such as asthma and diabetes...

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..The overall burden of CNS tumors appears to be relatively constant, but the significantly poorer survival for young people needs further rapid investigation...

..Genetic factors are unlikely to explain such a rapid change, implying an influence of environmental factors in disease aetiology. The similarity in rates by age group in the south Asian population is notable...

..Taking all children with malignant disease together, neither ethnicity nor socio-economic status appear to influence survival after taking other factors into consideration...

..Areas that exhibit high levels of population mixing do not necessarily possess raised rates of hospital admissions for infectious disease...

..To investigate incidence trends of all diabetes types in all children and young people and in the south Asian subpopulation...

..Variation in levels of ascertainment may partially explain this, although childhood environmental exposures related to infections will also be affected by levels of affluence...

..The links between diabetes and acute lymphoblastic leukemia observed for large regions are weaker for small areas. More powerful replications are needed for confirmation of these findings...

..There is potential to increase the proportion of children and young people with cancer who are referred to specialist palliative care services...

..Maternal exposure to solvents should further be investigated. These findings must invoke caution in the interpretation of risks reliant on self-reported occupational data...

..The English Department of Health has now issued guidelines to primary care trusts for the annual weighing and measuring of all children on entry to primary school and in year 6...

..To be certain that this is owing to cause rather than effect, and also as this is an important public health issue, further studies are warranted...

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..Clinical experience suggested the two conditions were seen in individuals more frequently than might be expected by chance...

..Resources could then be targeted towards those schools in greatest need...