Research Topics
| Andrew J FarrallSummaryAffiliation: University of Edinburgh Country: UK Publications
| Collaborators
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Detail Information
Publications
Blood-brain barrier: ageing and microvascular disease--systematic review and meta-analysisAndrew J Farrall
Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
Neurobiol Aging 30:337-52. 2009..30, 0.89, p<0.01). BBB permeability increases with normal ageing and may be an important mechanism in the initiation or worsening of cerebral microvascular disease. Further studies on the role of BBB permeability are urgently needed...
Factors influencing the detection of early CT signs of cerebral ischemia: an internet-based, international multiobserver studyJoanna M Wardlaw
Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
Stroke 38:1250-6. 2007..Early CT signs of cerebral ischemia are subtle. Little is known of which factors influence the detection of infarct signs. We compared neuroradiologists' scan readings with those of other specialists involved in the care of stroke patients...
Blood-brain barrier permeability in Alzheimer's disease: a case-control MRI studyJohn M Starr
Geriatric Medicine Unit, University of Edinburgh, Scotland, UK
Psychiatry Res 171:232-41. 2009..Though the extent of leakage was no greater than that of non-demented people of a similar age in this small sample, the temporal pattern differed, indicating different blood-brain-CSF compartmental kinetics...
Use of dynamic contrast-enhanced MRI to measure subtle blood-brain barrier abnormalitiesPaul A Armitage
Clinical Neurosciences, School of Molecular and Clinical Medicine, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, Scotland, UK
Magn Reson Imaging 29:305-14. 2011..Meanwhile, it is essential that future studies use an appropriate control group to minimize these influences...
A large web-based observer reliability study of early ischaemic signs on computed tomography. The Acute Cerebral CT Evaluation of Stroke Study (ACCESS)Joanna M Wardlaw
SINAPSE Collaboration, Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, United Kingdom
PLoS ONE 5:e15757. 2010..Scoring methods that code for the extent of brain ischaemia may improve stroke diagnosis and quantification of the impact of ischaemia...
Associations between diffusion and perfusion parameters, N-acetyl aspartate, and lactate in acute ischemic strokeVera Cvoro
Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, UK
Stroke 40:767-72. 2009..We used spectroscopic imaging to measure N-acetyl aspartate (NAA, a marker of normal neurons) and lactate (a marker of ischemia) to compare with diffusion and perfusion values in the diffusion lesion in acute ischemic stroke...
