Stephen Eyre

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. pmc ASSIMILATOR: a new tool to inform selection of associated genetic variants for functional studies
    Paul Martin
    Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK
    Bioinformatics 27:144-6. 2011
  2. pmc Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis
    Anne Hinks
    Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, The University of Manchester, Manchester M139PT, UK
    Arthritis Res Ther 13:R12. 2011
  3. pmc Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease
    Stephen Eyre
    Arthritis Research UK, Epidemiology Unit, Stopford Building, Oxford Road, The University of Manchester, Manchester M13 9PT, UK
    Arthritis Res Ther 12:R175. 2010
  4. pmc Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis
    Anne Hinks
    Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK
    Nat Genet 45:664-9. 2013
  5. pmc Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients
    Sebastien Viatte
    Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK
    Ann Rheum Dis 71:1984-90. 2012
  6. pmc Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis
    A Hinks
    Arthritis Research Campaign Epidemiology Unit ARC EU, University of Manchester, Manchester, UK
    Genes Immun 11:194-8. 2010
  7. pmc Association of the CCR5 gene with juvenile idiopathic arthritis
    A Hinks
    Manchester Academy of Health Sciences, The University of Manchester, UK
    Genes Immun 11:584-9. 2010
  8. ncbi request reprint Investigation of the MHC2TA gene, associated with rheumatoid arthritis in a Swedish population, in a UK rheumatoid arthritis cohort
    Stephen Eyre
    University of Manchester, Manchester, UK
    Arthritis Rheum 54:3417-22. 2006
  9. pmc Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity?
    Stephen Eyre
    ARC EU, University of Manchester, UK
    Arthritis Res Ther 8:R117. 2006
  10. pmc Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis
    John Bowes
    Arthritis Research UK, Epidemiology Unit, University of Manchester, Manchester, UK
    Hum Genet 128:627-33. 2010

Detail Information

Publications12

  1. pmc ASSIMILATOR: a new tool to inform selection of associated genetic variants for functional studies
    Paul Martin
    Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK
    Bioinformatics 27:144-6. 2011
    ..Here, we describe a program designed to quickly assimilate this data called ASSIMILATOR and validate the method by interrogating two regions to show its effectiveness...
  2. pmc Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis
    Anne Hinks
    Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, The University of Manchester, Manchester M139PT, UK
    Arthritis Res Ther 13:R12. 2011
    ..We, therefore, hypothesized that two well-established susceptibility loci for AS and Ps, ERAP1 and IL23R, could also confer susceptibility to these JIA subtypes...
  3. pmc Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease
    Stephen Eyre
    Arthritis Research UK, Epidemiology Unit, Stopford Building, Oxford Road, The University of Manchester, Manchester M13 9PT, UK
    Arthritis Res Ther 12:R175. 2010
    ..Here we have attempted to define overlapping genetic variants between rheumatoid arthritis (RA), type 1 diabetes (T1D) and coeliac disease (CeD)...
  4. pmc Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis
    Anne Hinks
    Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK
    Nat Genet 45:664-9. 2013
    ..In summary, this is the largest collection of JIA cases investigated so far and provides new insight into the genetic basis of this childhood autoimmune disease...
  5. pmc Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients
    Sebastien Viatte
    Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK
    Ann Rheum Dis 71:1984-90. 2012
    ..The authors therefore investigated confirmed RA susceptibility loci in a large cohort of anti-CCP negative RA subjects...
  6. pmc Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis
    A Hinks
    Arthritis Research Campaign Epidemiology Unit ARC EU, University of Manchester, Manchester, UK
    Genes Immun 11:194-8. 2010
    ..All results require validation in independent JIA data sets. Further characterisation of the specific causal variants will be required before functional studies can be performed...
  7. pmc Association of the CCR5 gene with juvenile idiopathic arthritis
    A Hinks
    Manchester Academy of Health Sciences, The University of Manchester, UK
    Genes Immun 11:584-9. 2010
    ....
  8. ncbi request reprint Investigation of the MHC2TA gene, associated with rheumatoid arthritis in a Swedish population, in a UK rheumatoid arthritis cohort
    Stephen Eyre
    University of Manchester, Manchester, UK
    Arthritis Rheum 54:3417-22. 2006
    ..Therefore, we undertook this study to investigate the association of the MHC2TA gene promoter with RA in a UK Caucasian population...
  9. pmc Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity?
    Stephen Eyre
    ARC EU, University of Manchester, UK
    Arthritis Res Ther 8:R117. 2006
    ....
  10. pmc Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis
    John Bowes
    Arthritis Research UK, Epidemiology Unit, University of Manchester, Manchester, UK
    Hum Genet 128:627-33. 2010
    ....
  11. doi request reprint A systematic investigation of confirmed autoimmune loci in early-onset psoriasis reveals an association with IL2/IL21
    R B Warren
    Dermatological Sciences, Salford Royal NHS Foundation Trust, The University of Manchester, Manchester Academic Health Science Centre, UK
    Br J Dermatol 164:660-4. 2011
    ..Many autoimmune diseases share common susceptibility loci suggesting similar underlying cellular mechanisms involved in disease expression...
  12. pmc Investigation of association between the TRAF family genes and RA susceptibility
    Catherine Potter
    Arthritis Research Campaign Epidemiology Unit, Stopford Building, University of Manchester, Manchester M13 9PT, UK
    Ann Rheum Dis 66:1322-6. 2007
    ..A study was undertaken to investigate the association between single nucleotide polymorphisms (SNPs) spanning six TRAF genes and RA in a British population...