Research Topics
Genomes and GenesSpecies | Stephen EyreSummaryAffiliation: University of Manchester Country: UK Publications
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Detail Information
Publications
ASSIMILATOR: a new tool to inform selection of associated genetic variants for functional studiesPaul Martin
Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK
Bioinformatics 27:144-6. 2011..AVAILABILITY: http://www.medicine.manchester.ac.uk/musculoskeletal/research/arc/genetics/bioinformatics/assimilator/...
Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritisAnne Hinks
Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, The University of Manchester, Manchester M139PT, UK
Arthritis Res Ther 13:R12. 2011..We, therefore, hypothesized that two well-established susceptibility loci for AS and Ps, ERAP1 and IL23R, could also confer susceptibility to these JIA subtypes...
Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac diseaseStephen Eyre
Arthritis Research UK, Epidemiology Unit, Stopford Building, Oxford Road, The University of Manchester, Manchester M13 9PT, UK
Arthritis Res Ther 12:R175. 2010..Here we have attempted to define overlapping genetic variants between rheumatoid arthritis (RA), type 1 diabetes (T1D) and coeliac disease (CeD)...
Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patientsSebastien Viatte
Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK
Ann Rheum Dis 71:1984-90. 2012..The authors therefore investigated confirmed RA susceptibility loci in a large cohort of anti-CCP negative RA subjects...
Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity?Stephen Eyre
ARC EU, University of Manchester, UK
Arthritis Res Ther 8:R117. 2006....
Association of the CCR5 gene with juvenile idiopathic arthritisA Hinks
Manchester Academy of Health Sciences, The University of Manchester, UK
Genes Immun 11:584-9. 2010....
Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritisA Hinks
Arthritis Research Campaign Epidemiology Unit ARC EU, University of Manchester, Manchester, UK
Genes Immun 11:194-8. 2010..All results require validation in independent JIA data sets. Further characterisation of the specific causal variants will be required before functional studies can be performed...
Investigation of the MHC2TA gene, associated with rheumatoid arthritis in a Swedish population, in a UK rheumatoid arthritis cohortStephen Eyre
University of Manchester, Manchester, UK
Arthritis Rheum 54:3417-22. 2006..Therefore, we undertook this study to investigate the association of the MHC2TA gene promoter with RA in a UK Caucasian population...
A systematic investigation of confirmed autoimmune loci in early-onset psoriasis reveals an association with IL2/IL21R B Warren
Dermatological Sciences, Salford Royal NHS Foundation Trust, The University of Manchester, Manchester Academic Health Science Centre, UK
Br J Dermatol 164:660-4. 2011..Many autoimmune diseases share common susceptibility loci suggesting similar underlying cellular mechanisms involved in disease expression...
Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritisJohn Bowes
Arthritis Research UK, Epidemiology Unit, University of Manchester, Manchester, UK
Hum Genet 128:627-33. 2010....
Investigation of association between the TRAF family genes and RA susceptibilityCatherine Potter
Arthritis Research Campaign Epidemiology Unit, Stopford Building, University of Manchester, Manchester M13 9PT, UK
Ann Rheum Dis 66:1322-6. 2007..A study was undertaken to investigate the association between single nucleotide polymorphisms (SNPs) spanning six TRAF genes and RA in a British population...
