Ian M Evans

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells
    Ian M Evans
    Department of Medicine, Centre for Cardiovascular Biology and Medicine, The Rayne Institute, University College London, UK
    Biochem J 429:565-72. 2010
  2. ncbi Protein kinase D in vascular biology and angiogenesis
    Ian M Evans
    Centre for Cardiovascular Biology and Medicine, Division of Medicine, University College London, London, UK
    IUBMB Life 63:spcone. 2011
  3. ncbi Protein kinase D in vascular biology and angiogenesis
    Ian M Evans
    Centre for Cardiovascular Biology and Medicine, Division of Medicine, University College London, London, UK
    IUBMB Life 63:258-63. 2011
  4. ncbi Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase
    Ian M Evans
    Centre for Cardiovascular Biology and Medicine, Department of Medicine, The Rayne Institute, University College London, 5 University Street, London WC1E 6JJ, United Kingdom
    Cell Signal 20:1375-84. 2008
  5. ncbi Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas
    Caroline Pellet-Many
    Centre for Cardiovascular Science and Medicine, Department of Medicine, The Rayne Institute, University College London, 5 University Street, London WC1E 6JJ, UK
    Biochem J 435:609-18. 2011
  6. ncbi Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells
    Ian M Evans
    UCL Division of Medicine, 5 University Street, London WC1E 6JJ, United Kingdom
    Mol Cell Biol 31:1174-85. 2011
  7. ncbi p130Cas: a key signalling node in health and disease
    Angela Barrett
    Centre for Cardiovascular Biology and Medicine, Division of Medicine, University College London, London WC1E 6JJ, United Kingdom
    Cell Signal 25:766-77. 2013
  8. ncbi The role of neuropilins in cell signalling
    Ian C Zachary
    Centre for Cardiovascular Science and Medicine, University College London, 5 University Street, London WC1E 6JJ, UK
    Biochem Soc Trans 37:1171-8. 2009
  9. ncbi Vascular endothelial growth factor synergistically enhances induction of E-selectin by tumor necrosis factor-alpha
    Anita K Stannard
    BHF Laboratories, Department of Medicine, The Rayne Building, University College London, 5 University Street, London WC1E 6JJ, United Kingdom
    Arterioscler Thromb Vasc Biol 27:494-502. 2007

Collaborators

Detail Information

Publications9

  1. ncbi Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells
    Ian M Evans
    Department of Medicine, Centre for Cardiovascular Biology and Medicine, The Rayne Institute, University College London, UK
    Biochem J 429:565-72. 2010
    ..CRT5, a novel specific PKD inhibitor, will greatly facilitate the study of the role of PKD signalling mechanisms in angiogenesis...
  2. ncbi Protein kinase D in vascular biology and angiogenesis
    Ian M Evans
    Centre for Cardiovascular Biology and Medicine, Division of Medicine, University College London, London, UK
    IUBMB Life 63:spcone. 2011
    ..Protein kinase D1/2 signaling in endothelial cells by Ian M. Evans and Ian C. Zachary, pp. 258-263...
  3. ncbi Protein kinase D in vascular biology and angiogenesis
    Ian M Evans
    Centre for Cardiovascular Biology and Medicine, Division of Medicine, University College London, London, UK
    IUBMB Life 63:258-63. 2011
    ..PKD is also emerging as a potentially important mediator of tumor growth and tumor angiogenesis and there is growing interest in PKD as a novel therapeutic target in cancer...
  4. ncbi Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase
    Ian M Evans
    Centre for Cardiovascular Biology and Medicine, Department of Medicine, The Rayne Institute, University College London, 5 University Street, London WC1E 6JJ, United Kingdom
    Cell Signal 20:1375-84. 2008
    ....
  5. ncbi Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas
    Caroline Pellet-Many
    Centre for Cardiovascular Science and Medicine, Department of Medicine, The Rayne Institute, University College London, 5 University Street, London WC1E 6JJ, UK
    Biochem J 435:609-18. 2011
    ..These results indicate a role for NRP1 and NRP1 glycosylation in mediating PDGF-induced VSMC migration, possibly by acting as a co-receptor for PDGFRα and via selective mobilization of a novel p130Cas tyrosine phosphorylation pathway...
  6. ncbi Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells
    Ian M Evans
    UCL Division of Medicine, 5 University Street, London WC1E 6JJ, United Kingdom
    Mol Cell Biol 31:1174-85. 2011
    ....
  7. ncbi p130Cas: a key signalling node in health and disease
    Angela Barrett
    Centre for Cardiovascular Biology and Medicine, Division of Medicine, University College London, London WC1E 6JJ, United Kingdom
    Cell Signal 25:766-77. 2013
    ....
  8. ncbi The role of neuropilins in cell signalling
    Ian C Zachary
    Centre for Cardiovascular Science and Medicine, University College London, 5 University Street, London WC1E 6JJ, UK
    Biochem Soc Trans 37:1171-8. 2009
    ..Growing evidence indicates, however, that NRP1 plays a selective role in signalling at least in part via its C-terminal domain and interaction with intracellular binding partners...
  9. ncbi Vascular endothelial growth factor synergistically enhances induction of E-selectin by tumor necrosis factor-alpha
    Anita K Stannard
    BHF Laboratories, Department of Medicine, The Rayne Building, University College London, 5 University Street, London WC1E 6JJ, United Kingdom
    Arterioscler Thromb Vasc Biol 27:494-502. 2007
    ..The regulation of endothelial cell adhesion molecules (CAMs) by vascular endothelial growth factor (VEGF) was investigated in cell cultures and in a rabbit model of atherogenic neointima formation...