Lél Eöry

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. doi request reprint Distributions of selectively constrained sites and deleterious mutation rates in the hominid and murid genomes
    Lél Eöry
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
    Mol Biol Evol 27:177-92. 2010
  2. pmc Contributions of protein-coding and regulatory change to adaptive molecular evolution in murid rodents
    Daniel L Halligan
    Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Genet 9:e1003995. 2013
  3. pmc Inference of mutation parameters and selective constraint in mammalian coding sequences by approximate Bayesian computation
    Peter D Keightley
    Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, EH9 3JT, United Kingdom
    Genetics 187:1153-61. 2011

Detail Information

Publications3

  1. doi request reprint Distributions of selectively constrained sites and deleterious mutation rates in the hominid and murid genomes
    Lél Eöry
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
    Mol Biol Evol 27:177-92. 2010
    ..Including coding and noncoding sites, we estimate that the genomic deleterious mutation rate U = 4.2. The mutational load predicted under a multiplicative model is therefore about 99% in hominids...
  2. pmc Contributions of protein-coding and regulatory change to adaptive molecular evolution in murid rodents
    Daniel L Halligan
    Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Genet 9:e1003995. 2013
    ..We conclude that although there appear to be many more adaptive noncoding changes, substitutions in proteins may dominate phenotypic evolution...
  3. pmc Inference of mutation parameters and selective constraint in mammalian coding sequences by approximate Bayesian computation
    Peter D Keightley
    Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, EH9 3JT, United Kingdom
    Genetics 187:1153-61. 2011
    ..Synonymous site selective constraint is weakest in murids, a surprising result, considering that murid effective population sizes are likely to be considerably higher than the other two taxa...