Lynda Erskine

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Integrated interactions between chondroitin sulphate proteoglycans and weak dc electric fields regulate nerve growth cone guidance in vitro
    L Erskine
    Department of Biomedical Sciences, Institute of Medical Sciences, University of Aberdeen, Foresterhill, UK
    J Cell Sci 110:1957-65. 1997
  2. ncbi request reprint The retinal ganglion cell axon's journey: insights into molecular mechanisms of axon guidance
    Lynda Erskine
    Division of Visual Science, Institute of Ophthalmology, University College London, 11 43 Bath Street, London, EC1V 9EL, UK
    Dev Biol 308:1-14. 2007
  3. pmc Robo2 is required for Slit-mediated intraretinal axon guidance
    Hannah Thompson
    Institute of Ophthalmology, University College London, England, UK
    Dev Biol 335:418-26. 2009
  4. ncbi request reprint Slit proteins regulate distinct aspects of retinal ganglion cell axon guidance within dorsal and ventral retina
    Hannah Thompson
    Division of Visual Science, Institute of Ophthalmology, University College London, London EC1V 9EL, United Kingdom
    J Neurosci 26:8082-91. 2006
  5. pmc VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm
    Lynda Erskine
    School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, UK
    Neuron 70:951-65. 2011
  6. ncbi request reprint The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons
    William Andrews
    Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK
    Dev Biol 313:648-58. 2008
  7. ncbi request reprint Slits contribute to the guidance of retinal ganglion cell axons in the mammalian optic tract
    Hannah Thompson
    Divisions of Visual Science and Molecular Genetics, Institute of Ophthalmology, University College London, 11 43 Bath Street, London, EC1V 9EL, UK
    Dev Biol 296:476-84. 2006
  8. ncbi request reprint Differential progenitor dispersal and the spatial origin of early neurons can explain the predominance of single-phenotype clones in the chick hindbrain
    J D Clarke
    Department of Anatomy and Developmental Biology, University College London, United Kingdom
    Dev Dyn 212:14-26. 1998
  9. ncbi request reprint Variations in the architecture and development of the vertebrate optic chiasm
    Glen Jeffery
    Institute of Ophthalmology, University College London, Bath Street, London EC1V 9EL, UK
    Prog Retin Eye Res 24:721-53. 2005
  10. ncbi request reprint Developmental expression profile of the optic atrophy gene product: OPA1 is not localized exclusively in the mammalian retinal ganglion cell layer
    Saima Aijaz
    Department of Molecular Genetics, Institute of Ophthalmology, London, United Kingdom
    Invest Ophthalmol Vis Sci 45:1667-73. 2004

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Integrated interactions between chondroitin sulphate proteoglycans and weak dc electric fields regulate nerve growth cone guidance in vitro
    L Erskine
    Department of Biomedical Sciences, Institute of Medical Sciences, University of Aberdeen, Foresterhill, UK
    J Cell Sci 110:1957-65. 1997
    ....
  2. ncbi request reprint The retinal ganglion cell axon's journey: insights into molecular mechanisms of axon guidance
    Lynda Erskine
    Division of Visual Science, Institute of Ophthalmology, University College London, 11 43 Bath Street, London, EC1V 9EL, UK
    Dev Biol 308:1-14. 2007
    ....
  3. pmc Robo2 is required for Slit-mediated intraretinal axon guidance
    Hannah Thompson
    Institute of Ophthalmology, University College London, England, UK
    Dev Biol 335:418-26. 2009
    ....
  4. ncbi request reprint Slit proteins regulate distinct aspects of retinal ganglion cell axon guidance within dorsal and ventral retina
    Hannah Thompson
    Division of Visual Science, Institute of Ophthalmology, University College London, London EC1V 9EL, United Kingdom
    J Neurosci 26:8082-91. 2006
    ..These data demonstrate clearly that multiple mechanisms exist in the retina for axon guidance of which Slits are an important component...
  5. pmc VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm
    Lynda Erskine
    School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, UK
    Neuron 70:951-65. 2011
    ..These findings have identified a permissive midline signal for axons at the chiasm midline and provide in vivo evidence that VEGF-A is an essential axon guidance cue...
  6. ncbi request reprint The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons
    William Andrews
    Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK
    Dev Biol 313:648-58. 2008
    ....
  7. ncbi request reprint Slits contribute to the guidance of retinal ganglion cell axons in the mammalian optic tract
    Hannah Thompson
    Divisions of Visual Science and Molecular Genetics, Institute of Ophthalmology, University College London, 11 43 Bath Street, London, EC1V 9EL, UK
    Dev Biol 296:476-84. 2006
    ..This demonstrates that Slits play an important role in directing the guidance of post-crossing RGC axons within the optic tracts but are not required for target innervation...
  8. ncbi request reprint Differential progenitor dispersal and the spatial origin of early neurons can explain the predominance of single-phenotype clones in the chick hindbrain
    J D Clarke
    Department of Anatomy and Developmental Biology, University College London, United Kingdom
    Dev Dyn 212:14-26. 1998
    ..e., motor neurons...
  9. ncbi request reprint Variations in the architecture and development of the vertebrate optic chiasm
    Glen Jeffery
    Institute of Ophthalmology, University College London, Bath Street, London EC1V 9EL, UK
    Prog Retin Eye Res 24:721-53. 2005
    ..This review aims to highlight key issues in the organisation and development of the vertebrate optic chiasm with a focus on comparing and contrasting the data that has been gleaned to date from different vertebrate groups...
  10. ncbi request reprint Developmental expression profile of the optic atrophy gene product: OPA1 is not localized exclusively in the mammalian retinal ganglion cell layer
    Saima Aijaz
    Department of Molecular Genetics, Institute of Ophthalmology, London, United Kingdom
    Invest Ophthalmol Vis Sci 45:1667-73. 2004
    ..Because the Bst/+ mouse has been postulated as a model of ADOA, the mOPA1 expression in the Bst/+ retina was also examined...
  11. ncbi request reprint Focus on molecules: nyctalopin
    Subathra Poopalasundaram
    Institute of Ophthalmology, University College London, 11 43 Bath Street, London EC1V 9EL, UK
    Exp Eye Res 81:627-8. 2005
  12. ncbi request reprint Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system
    Andrew S Plump
    Department of Anatomy, Howard Hughes Medical Institute, CA, USA
    Neuron 33:219-32. 2002
    ..Our results indicate that Slit proteins repel retinal axons in vivo and cooperate to establish a corridor through which the axons are channeled, thereby helping define the site in the ventral diencephalon where the optic chiasm forms...
  13. ncbi request reprint Spatiotemporal features of early neuronogenesis differ in wild-type and albino mouse retina
    Rivka A Rachel
    Center for Neurobiology and Behavior, Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Neurosci 22:4249-63. 2002
    ..These results point to spatiotemporal defects in neuronal production in the albino retina, which could perturb expression of genes that specify cell fate, number, and/or projection phenotype...
  14. pmc Permissive corridor and diffusible gradients direct medial ganglionic eminence cell migration to the neocortex
    Hynek Wichterle
    The Rockefeller University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 100:727-32. 2003
    ..In addition, we propose that chemotactic guidance cues superimposed over the permissive corridor facilitate efficient dorsal migration of MGE cells...
  15. ncbi request reprint Foxd1 is required for proper formation of the optic chiasm
    Eloisa Herrera
    Departments of Pathology, Anatomy and Cell Biology and Center for Neurobiology and Behavior, Columbia University, College of Physicians and Surgeons, 630 West 168th Street, New York, NY 10032, USA
    Development 131:5727-39. 2004
    ....
  16. pmc Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm
    Scott E Williams
    Departments of Pathology, Anatomy and Cell Biology, Center for Neurobiology and Behavior, Columbia University, College of Physicians and Surgeons, 630 West 168th Street, New York, NY 10032, USA
    Neuron 39:919-35. 2003
    ..EphB1 null mice exhibit a dramatically reduced ipsilateral projection, suggesting that this receptor contributes to the formation of the ipsilateral retinal projection, most likely through its repulsive interaction with ephrin-B2...
  17. pmc Back to basics - ephrins, axonal guidance, neuroprotection and glaucoma
    M Francesca Cordeiro
    Br J Ophthalmol 91:1106. 2007