Clett Erridge

Summary

Affiliation: University of Leicester
Country: UK

Publications

  1. doi request reprint Saturated fatty acids do not directly stimulate Toll-like receptor signaling
    Clett Erridge
    Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK
    Arterioscler Thromb Vasc Biol 29:1944-9. 2009
  2. doi request reprint Endogenous ligands of TLR2 and TLR4: agonists or assistants?
    Clett Erridge
    Department of Cardiovascular Sciences, Glenfield General Hospital, University of Leicester, Leicester, UK, LE3 9QP
    J Leukoc Biol 87:989-99. 2010
  3. doi request reprint Stimulants of Toll-like receptor (TLR)-2 and TLR-4 are abundant in certain minimally-processed vegetables
    Clett Erridge
    Department of Cardiovascular Sciences, Glenfield General Hospital, University of Leicester, Leicester LE3 9QP, UK
    Food Chem Toxicol 49:1464-7. 2011
  4. pmc The induction of colitis and ileitis in mice is associated with marked increases in intestinal concentrations of stimulants of TLRs 2, 4, and 5
    Clett Erridge
    Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom
    PLoS ONE 5:e9125. 2010
  5. doi request reprint The capacity of foodstuffs to induce innate immune activation of human monocytes in vitro is dependent on food content of stimulants of Toll-like receptors 2 and 4
    Clett Erridge
    Department of Cardiovascular Sciences, University of Leicester, Glenfield General Hospital, Groby Road, Leicester LE3 9QP, UK
    Br J Nutr 105:15-23. 2011
  6. doi request reprint Diet, commensals and the intestine as sources of pathogen-associated molecular patterns in atherosclerosis, type 2 diabetes and non-alcoholic fatty liver disease
    Clett Erridge
    Department of Cardiovascular Sciences, Glenfield General Hospital, University of Leicester, Leicester LE3 9QP, UK
    Atherosclerosis 216:1-6. 2011
  7. doi request reprint Accumulation of stimulants of Toll-like receptor (TLR)-2 and TLR4 in meat products stored at 5 °C
    Clett Erridge
    Dept of Cardiovascular Sciences, Glenfield General Hospital, Univ of Leicester, Groby Road, Leicester LE3 9QP, UK
    J Food Sci 76:H72-9. 2011
  8. ncbi request reprint Diverse bacteria promote macrophage foam cell formation via Toll-like receptor-dependent lipid body biosynthesis
    Giovanna Nicolaou
    Department of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK
    J Atheroscler Thromb 19:137-48. 2012

Collaborators

Detail Information

Publications8

  1. doi request reprint Saturated fatty acids do not directly stimulate Toll-like receptor signaling
    Clett Erridge
    Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK
    Arterioscler Thromb Vasc Biol 29:1944-9. 2009
    ....
  2. doi request reprint Endogenous ligands of TLR2 and TLR4: agonists or assistants?
    Clett Erridge
    Department of Cardiovascular Sciences, Glenfield General Hospital, University of Leicester, Leicester, UK, LE3 9QP
    J Leukoc Biol 87:989-99. 2010
    ..The relevance of this possibility to the pathogenesis of chronic inflammatory diseases, tumor surveillance, and autoimmunity is discussed...
  3. doi request reprint Stimulants of Toll-like receptor (TLR)-2 and TLR-4 are abundant in certain minimally-processed vegetables
    Clett Erridge
    Department of Cardiovascular Sciences, Glenfield General Hospital, University of Leicester, Leicester LE3 9QP, UK
    Food Chem Toxicol 49:1464-7. 2011
    ..In conclusion, the modern trend towards eating minimally processed vegetables rather than whole foods is likely to be associated with increased oral exposure to stimulants of TLR2 and TLR4...
  4. pmc The induction of colitis and ileitis in mice is associated with marked increases in intestinal concentrations of stimulants of TLRs 2, 4, and 5
    Clett Erridge
    Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom
    PLoS ONE 5:e9125. 2010
    ..We aimed to establish if intestinal concentrations of proinflammatory bacterial ligands of TLR2, TLR4, or TLR5 may be altered in murine IBD models, and to characterize which of the major bacterial groups may contribute to each signal...
  5. doi request reprint The capacity of foodstuffs to induce innate immune activation of human monocytes in vitro is dependent on food content of stimulants of Toll-like receptors 2 and 4
    Clett Erridge
    Department of Cardiovascular Sciences, University of Leicester, Glenfield General Hospital, Groby Road, Leicester LE3 9QP, UK
    Br J Nutr 105:15-23. 2011
    ..In conclusion, apparently unspoiled foodstuffs can contain large quantities of stimulants of TLR2 and TLR4, both of which may regulate their capacity to stimulate inflammatory signalling...
  6. doi request reprint Diet, commensals and the intestine as sources of pathogen-associated molecular patterns in atherosclerosis, type 2 diabetes and non-alcoholic fatty liver disease
    Clett Erridge
    Department of Cardiovascular Sciences, Glenfield General Hospital, University of Leicester, Leicester LE3 9QP, UK
    Atherosclerosis 216:1-6. 2011
    ..Finally, the major mechanisms by which TLR-stimulants may gain access to the circulation to promote systemic low-grade inflammation are considered...
  7. doi request reprint Accumulation of stimulants of Toll-like receptor (TLR)-2 and TLR4 in meat products stored at 5 °C
    Clett Erridge
    Dept of Cardiovascular Sciences, Glenfield General Hospital, Univ of Leicester, Groby Road, Leicester LE3 9QP, UK
    J Food Sci 76:H72-9. 2011
    ..In summary, storage conditions and microbial flora critically regulate the kinetics of TLR2- and TLR4-stimulant accumulation in meat products and these may retain biological activity after cooking...
  8. ncbi request reprint Diverse bacteria promote macrophage foam cell formation via Toll-like receptor-dependent lipid body biosynthesis
    Giovanna Nicolaou
    Department of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK
    J Atheroscler Thromb 19:137-48. 2012
    ..Atherosclerotic lesions contain DNA signatures from a wide variety of bacteria, although little is known of how exposure to these organisms may modulate the accumulation of lipids in macrophages...