Clett Erridge

Summary

Affiliation: University of Leicester
Country: UK

Publications

  1. ncbi Saturated fatty acids do not directly stimulate Toll-like receptor signaling
    Clett Erridge
    Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK
    Arterioscler Thromb Vasc Biol 29:1944-9. 2009
  2. ncbi The induction of colitis and ileitis in mice is associated with marked increases in intestinal concentrations of stimulants of TLRs 2, 4, and 5
    Clett Erridge
    Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom
    PLoS ONE 5:e9125. 2010
  3. ncbi Endogenous ligands of TLR2 and TLR4: agonists or assistants?
    Clett Erridge
    Department of Cardiovascular Sciences, Glenfield General Hospital, University of Leicester, Leicester, UK, LE3 9QP
    J Leukoc Biol 87:989-99. 2010
  4. ncbi The capacity of foodstuffs to induce innate immune activation of human monocytes in vitro is dependent on food content of stimulants of Toll-like receptors 2 and 4
    Clett Erridge
    Department of Cardiovascular Sciences, University of Leicester, Glenfield General Hospital, Groby Road, Leicester LE3 9QP, UK
    Br J Nutr 105:15-23. 2011
  5. ncbi Stimulants of Toll-like receptor (TLR)-2 and TLR-4 are abundant in certain minimally-processed vegetables
    Clett Erridge
    Department of Cardiovascular Sciences, Glenfield General Hospital, University of Leicester, Leicester LE3 9QP, UK
    Food Chem Toxicol 49:1464-7. 2011
  6. ncbi Diet, commensals and the intestine as sources of pathogen-associated molecular patterns in atherosclerosis, type 2 diabetes and non-alcoholic fatty liver disease
    Clett Erridge
    Department of Cardiovascular Sciences, Glenfield General Hospital, University of Leicester, Leicester LE3 9QP, UK
    Atherosclerosis 216:1-6. 2011
  7. ncbi Accumulation of stimulants of Toll-like receptor (TLR)-2 and TLR4 in meat products stored at 5 °C
    Clett Erridge
    Dept of Cardiovascular Sciences, Glenfield General Hospital, Univ of Leicester, Groby Road, Leicester LE3 9QP, UK
    J Food Sci 76:H72-9. 2011
  8. ncbi Diverse bacteria promote macrophage foam cell formation via Toll-like receptor-dependent lipid body biosynthesis
    Giovanna Nicolaou
    Department of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK
    J Atheroscler Thromb 19:137-48. 2012

Collaborators

Detail Information

Publications8

  1. ncbi Saturated fatty acids do not directly stimulate Toll-like receptor signaling
    Clett Erridge
    Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK
    Arterioscler Thromb Vasc Biol 29:1944-9. 2009
    ....
  2. ncbi The induction of colitis and ileitis in mice is associated with marked increases in intestinal concentrations of stimulants of TLRs 2, 4, and 5
    Clett Erridge
    Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom
    PLoS ONE 5:e9125. 2010
    ..We aimed to establish if intestinal concentrations of proinflammatory bacterial ligands of TLR2, TLR4, or TLR5 may be altered in murine IBD models, and to characterize which of the major bacterial groups may contribute to each signal...
  3. ncbi Endogenous ligands of TLR2 and TLR4: agonists or assistants?
    Clett Erridge
    Department of Cardiovascular Sciences, Glenfield General Hospital, University of Leicester, Leicester, UK, LE3 9QP
    J Leukoc Biol 87:989-99. 2010
    ..The relevance of this possibility to the pathogenesis of chronic inflammatory diseases, tumor surveillance, and autoimmunity is discussed...
  4. ncbi The capacity of foodstuffs to induce innate immune activation of human monocytes in vitro is dependent on food content of stimulants of Toll-like receptors 2 and 4
    Clett Erridge
    Department of Cardiovascular Sciences, University of Leicester, Glenfield General Hospital, Groby Road, Leicester LE3 9QP, UK
    Br J Nutr 105:15-23. 2011
    ..In conclusion, apparently unspoiled foodstuffs can contain large quantities of stimulants of TLR2 and TLR4, both of which may regulate their capacity to stimulate inflammatory signalling...
  5. ncbi Stimulants of Toll-like receptor (TLR)-2 and TLR-4 are abundant in certain minimally-processed vegetables
    Clett Erridge
    Department of Cardiovascular Sciences, Glenfield General Hospital, University of Leicester, Leicester LE3 9QP, UK
    Food Chem Toxicol 49:1464-7. 2011
    ..In conclusion, the modern trend towards eating minimally processed vegetables rather than whole foods is likely to be associated with increased oral exposure to stimulants of TLR2 and TLR4...
  6. ncbi Diet, commensals and the intestine as sources of pathogen-associated molecular patterns in atherosclerosis, type 2 diabetes and non-alcoholic fatty liver disease
    Clett Erridge
    Department of Cardiovascular Sciences, Glenfield General Hospital, University of Leicester, Leicester LE3 9QP, UK
    Atherosclerosis 216:1-6. 2011
    ..Finally, the major mechanisms by which TLR-stimulants may gain access to the circulation to promote systemic low-grade inflammation are considered...
  7. ncbi Accumulation of stimulants of Toll-like receptor (TLR)-2 and TLR4 in meat products stored at 5 °C
    Clett Erridge
    Dept of Cardiovascular Sciences, Glenfield General Hospital, Univ of Leicester, Groby Road, Leicester LE3 9QP, UK
    J Food Sci 76:H72-9. 2011
    ..These assays may also be used to monitor the historical microbial flora in food products after cooking or other forms of food processing may have rendered the original microflora nonviable...
  8. ncbi Diverse bacteria promote macrophage foam cell formation via Toll-like receptor-dependent lipid body biosynthesis
    Giovanna Nicolaou
    Department of Cardiovascular Sciences, Glenfield Hospital, Leicester, UK
    J Atheroscler Thromb 19:137-48. 2012
    ..Atherosclerotic lesions contain DNA signatures from a wide variety of bacteria, although little is known of how exposure to these organisms may modulate the accumulation of lipids in macrophages...