Clett Erridge

Summary

Affiliation: University of Strathclyde
Country: UK

Publications

  1. pmc Oxidized phospholipid inhibition of toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4: roles for CD14, LPS-binding protein, and MD2 as targets for specificity of inhibition
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Sciences, Univesity of Strathclyde, 204 George St, Glasgow G1 1XW, United Kingdom
    J Biol Chem 283:24748-59. 2008
  2. doi The roles of pathogen-associated molecular patterns in atherosclerosis
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 204 George Street, Glasgow G1 1XW, UK
    Trends Cardiovasc Med 18:52-6. 2008
  3. ncbi A high-fat meal induces low-grade endotoxemia: evidence of a novel mechanism of postprandial inflammation
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow, United Kingdom
    Am J Clin Nutr 86:1286-92. 2007
  4. ncbi 25-Hydroxycholesterol, 7beta-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK
    Free Radic Res 41:260-6. 2007
  5. ncbi Toll-like receptor 4 signalling is neither sufficient nor required for oxidised phospholipid mediated induction of interleukin-8 expression
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 204 George Street, Glasgow G1 1XW, UK
    Atherosclerosis 193:77-85. 2007
  6. ncbi Acinetobacter baumannii lipopolysaccharides are potent stimulators of human monocyte activation via Toll-like receptor 4 signalling
    Clett Erridge
    Department of Bioscience, 204 George Street, University of Strathclyde, Glasgow G1 1XW, UK
    J Med Microbiol 56:165-71. 2007
  7. ncbi Non-enterobacterial endotoxins stimulate human coronary artery but not venous endothelial cell activation via Toll-like receptor 2
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 204 George Street, Glasgow, G1 1XW, UK
    Cardiovasc Res 73:181-9. 2007
  8. ncbi Oxidised phospholipid regulation of Toll-like receptor signalling
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK
    Redox Rep 12:76-80. 2007
  9. ncbi Lipopolysaccharides of Bacteroides fragilis, Chlamydia trachomatis and Pseudomonas aeruginosa signal via toll-like receptor 2
    Clett Erridge
    Medical Microbiology, Centre for Infectious Diseases, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK
    J Med Microbiol 53:735-40. 2004
  10. pmc Monocytes heterozygous for the Asp299Gly and Thr399Ile mutations in the Toll-like receptor 4 gene show no deficit in lipopolysaccharide signalling
    Clett Erridge
    Department of Medical Microbiology, University of Edinburgh Medical School, Edinburgh, EH8 9AG Scotland, UK
    J Exp Med 197:1787-91. 2003

Detail Information

Publications12

  1. pmc Oxidized phospholipid inhibition of toll-like receptor (TLR) signaling is restricted to TLR2 and TLR4: roles for CD14, LPS-binding protein, and MD2 as targets for specificity of inhibition
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Sciences, Univesity of Strathclyde, 204 George St, Glasgow G1 1XW, United Kingdom
    J Biol Chem 283:24748-59. 2008
    ....
  2. doi The roles of pathogen-associated molecular patterns in atherosclerosis
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 204 George Street, Glasgow G1 1XW, UK
    Trends Cardiovasc Med 18:52-6. 2008
    ....
  3. ncbi A high-fat meal induces low-grade endotoxemia: evidence of a novel mechanism of postprandial inflammation
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow, United Kingdom
    Am J Clin Nutr 86:1286-92. 2007
    ..Endotoxin circulates at low concentrations in the blood of all healthy individuals, although elevated concentrations are associated with an increased risk of atherosclerosis...
  4. ncbi 25-Hydroxycholesterol, 7beta-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK
    Free Radic Res 41:260-6. 2007
    ..We conclude that although the oxysterols examined in this study may contribute to increased expression of certain inflammatory genes, this occurs by mechanisms independent of TLR signalling...
  5. ncbi Toll-like receptor 4 signalling is neither sufficient nor required for oxidised phospholipid mediated induction of interleukin-8 expression
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 204 George Street, Glasgow G1 1XW, UK
    Atherosclerosis 193:77-85. 2007
    ....
  6. ncbi Acinetobacter baumannii lipopolysaccharides are potent stimulators of human monocyte activation via Toll-like receptor 4 signalling
    Clett Erridge
    Department of Bioscience, 204 George Street, University of Strathclyde, Glasgow G1 1XW, UK
    J Med Microbiol 56:165-71. 2007
    ..Whole UV-killed cells of A. baumannii and Acinetobacter 'genomospecies 9' stimulated both TLR2- and TLR4-dependent signalling, whereas pure endotoxins of all investigated strains induced signalling via TLR4, but not TLR2...
  7. ncbi Non-enterobacterial endotoxins stimulate human coronary artery but not venous endothelial cell activation via Toll-like receptor 2
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 204 George Street, Glasgow, G1 1XW, UK
    Cardiovasc Res 73:181-9. 2007
    ..To determine whether non-enterobacterial endotoxins, which are likely to constitute the majority of the circulating endotoxin pool, may stimulate coronary artery endothelial cell activation...
  8. ncbi Oxidised phospholipid regulation of Toll-like receptor signalling
    Clett Erridge
    Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK
    Redox Rep 12:76-80. 2007
    ..As the interaction between OxPLs and TLRs may play a significant role in chronic inflammatory disease processes, consideration is given in this review to the potential role of OxPLs in the regulation of TLR-signalling...
  9. ncbi Lipopolysaccharides of Bacteroides fragilis, Chlamydia trachomatis and Pseudomonas aeruginosa signal via toll-like receptor 2
    Clett Erridge
    Medical Microbiology, Centre for Infectious Diseases, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK
    J Med Microbiol 53:735-40. 2004
    ....
  10. pmc Monocytes heterozygous for the Asp299Gly and Thr399Ile mutations in the Toll-like receptor 4 gene show no deficit in lipopolysaccharide signalling
    Clett Erridge
    Department of Medical Microbiology, University of Edinburgh Medical School, Edinburgh, EH8 9AG Scotland, UK
    J Exp Med 197:1787-91. 2003
    ..We propose that the relatively high frequency of these mutations in the Caucasian population may reflect modified responses of carriers to alternative TLR4 agonists...
  11. ncbi Structure and function of lipopolysaccharides
    Clett Erridge
    Medical Microbiology, University of Edinburgh Medical School, Edinburgh, Scotland, EH8 9AG, UK
    Microbes Infect 4:837-51. 2002
    ..Consideration is given in this review to the relationship between structure and function of these lipopolysaccharides...
  12. ncbi The biological activity of a liposomal complete core lipopolysaccharide vaccine
    Clett Erridge
    Medical Microbiology, University of Edinburgh Medical School, Teviot Place, Edinburgh EH8 9AG, UK
    J Endotoxin Res 8:39-46. 2002
    ..Therefore, as well as inducing specific antibody responses, liposomal LPS demonstrates characteristics suitable for use as a vaccine to be used in human beings...