Laura Else

Summary

Affiliation: University of Liverpool
Country: UK

Publications

  1. doi request reprint Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid)
    Laura J Else
    Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK
    Antivir Ther 16:1139-47. 2011
  2. pmc Pharmacokinetics of lamivudine and lamivudine-triphosphate after administration of 300 milligrams and 150 milligrams once daily to healthy volunteers: results of the ENCORE 2 study
    Laura J Else
    Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom
    Antimicrob Agents Chemother 56:1427-33. 2012
  3. doi request reprint Validation of a rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay for the simultaneous determination of existing and new antiretroviral compounds
    Laura Else
    Department of Pharmacology and Therapeutics, University of Liverpool, Pharmacology Research Laboratories, Liverpool, UK
    J Chromatogr B Analyt Technol Biomed Life Sci 878:1455-65. 2010
  4. pmc Improved oral bioavailability of lopinavir in melt-extruded tablet formulation reduces impact of third trimester on lopinavir plasma concentrations
    L J Else
    Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom
    Antimicrob Agents Chemother 56:816-24. 2012
  5. doi request reprint Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the male and female genital tract
    Laura J Else
    Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK
    Antivir Ther 16:1149-67. 2011
  6. pmc Sequential population pharmacokinetic modeling of lopinavir and ritonavir in healthy volunteers and assessment of different dosing strategies
    Laura Dickinson
    Department of Pharmacology, University of Liverpool, Pharmacology Research Laboratories, Block H, First Floor, 70 Pembroke Place, Liverpool L693GF, United Kingdom
    Antimicrob Agents Chemother 55:2775-82. 2011

Detail Information

Publications6

  1. doi request reprint Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid)
    Laura J Else
    Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK
    Antivir Ther 16:1139-47. 2011
    ..More comprehensive in vivo pharmacokinetic data are required to justify the potential use of these agents as safe and effective options during pregnancy...
  2. pmc Pharmacokinetics of lamivudine and lamivudine-triphosphate after administration of 300 milligrams and 150 milligrams once daily to healthy volunteers: results of the ENCORE 2 study
    Laura J Else
    Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom
    Antimicrob Agents Chemother 56:1427-33. 2012
    ..68 to 0.99), and 0.70 (0.61 to 0.82), respectively. We found that 3TC at 150 mg is not bioequivalent to the standard regimen of 300 mg, indicating that saturation of cytosine phosphorylation pathways is not achieved at a dose of 150 mg...
  3. doi request reprint Validation of a rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay for the simultaneous determination of existing and new antiretroviral compounds
    Laura Else
    Department of Pharmacology and Therapeutics, University of Liverpool, Pharmacology Research Laboratories, Liverpool, UK
    J Chromatogr B Analyt Technol Biomed Life Sci 878:1455-65. 2010
    ..The method described is being successfully applied to measure plasma antiretroviral concentrations from samples obtained from clinical pharmacokinetic studies...
  4. pmc Improved oral bioavailability of lopinavir in melt-extruded tablet formulation reduces impact of third trimester on lopinavir plasma concentrations
    L J Else
    Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom
    Antimicrob Agents Chemother 56:816-24. 2012
    ....
  5. doi request reprint Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the male and female genital tract
    Laura J Else
    Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK
    Antivir Ther 16:1149-67. 2011
    ....
  6. pmc Sequential population pharmacokinetic modeling of lopinavir and ritonavir in healthy volunteers and assessment of different dosing strategies
    Laura Dickinson
    Department of Pharmacology, University of Liverpool, Pharmacology Research Laboratories, Block H, First Floor, 70 Pembroke Place, Liverpool L693GF, United Kingdom
    Antimicrob Agents Chemother 55:2775-82. 2011
    ..The model allows a better understanding of the interaction between lopinavir and ritonavir and may allow a better prediction of lopinavir concentrations and assessments of different dosing strategies...