R John Ellis

Summary

Affiliation: University of Warwick
Country: UK

Publications

  1. ncbi request reprint Molecular chaperones: assisting assembly in addition to folding
    R John Ellis
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Trends Biochem Sci 31:395-401. 2006
  2. ncbi request reprint Protein aggregation in crowded environments
    R John Ellis
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Biol Chem 387:485-97. 2006
  3. ncbi request reprint Protein misassembly: macromolecular crowding and molecular chaperones
    R John Ellis
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Adv Exp Med Biol 594:1-13. 2007
  4. ncbi request reprint Macromolecular crowding: an important but neglected aspect of the intracellular environment
    R J Ellis
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Curr Opin Struct Biol 11:114-9. 2001
  5. ncbi request reprint Chaperomics: in vivo GroEL function defined
    R John Ellis
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Curr Biol 15:R661-3. 2005
  6. ncbi request reprint Protein folding: importance of the Anfinsen cage
    R John Ellis
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Curr Biol 13:R881-3. 2003
  7. ncbi request reprint Molecular chaperones: inside and outside the Anfinsen cage
    R J Ellis
    Department of Biological Sciences, University of Warwick, CV4 7AL, Coventry, UK
    Curr Biol 11:R1038-40. 2001
  8. ncbi request reprint Macromolecular crowding: obvious but underappreciated
    R J Ellis
    Dept of Biological Sciences, University of Warwick, Coventry, CV4 7AL, UK
    Trends Biochem Sci 26:597-604. 2001
  9. pmc Assembly chaperones: a perspective
    R John Ellis
    School of Life Sciences, University of Warwick, Coventry CV4 7AL, UK
    Philos Trans R Soc Lond B Biol Sci 368:20110398. 2013
  10. ncbi request reprint The attention of researchers on the biological process of protein folding has turned to the formation and properties of aggregates
    R John Ellis
    Semin Cell Dev Biol 15:1-2. 2004

Detail Information

Publications14

  1. ncbi request reprint Molecular chaperones: assisting assembly in addition to folding
    R John Ellis
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Trends Biochem Sci 31:395-401. 2006
    ....
  2. ncbi request reprint Protein aggregation in crowded environments
    R John Ellis
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Biol Chem 387:485-97. 2006
    ..This review discusses the quantitative effects of crowding on protein aggregation and the role of molecular chaperones in combating this problem...
  3. ncbi request reprint Protein misassembly: macromolecular crowding and molecular chaperones
    R John Ellis
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Adv Exp Med Biol 594:1-13. 2007
    ..This review discusses some of the basic evidence and key concepts relating to this conclusion...
  4. ncbi request reprint Macromolecular crowding: an important but neglected aspect of the intracellular environment
    R J Ellis
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Curr Opin Struct Biol 11:114-9. 2001
    ..It is proposed that the addition of crowding agents should become as routine as controlling pH and ionic strength if we are to meet the objective of studying biological molecules under more physiologically relevant conditions...
  5. ncbi request reprint Chaperomics: in vivo GroEL function defined
    R John Ellis
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Curr Biol 15:R661-3. 2005
    ..These proteins are enriched in alpha/beta domains and 13 are essential for growth...
  6. ncbi request reprint Protein folding: importance of the Anfinsen cage
    R John Ellis
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Curr Biol 13:R881-3. 2003
  7. ncbi request reprint Molecular chaperones: inside and outside the Anfinsen cage
    R J Ellis
    Department of Biological Sciences, University of Warwick, CV4 7AL, Coventry, UK
    Curr Biol 11:R1038-40. 2001
    ..Refolding aconitase is too large to enter the cage but reversible binding to GroEL reduces its aggregration. Unexpectedly, confinement in the cage increases the rate of refolding of rubisco, but not rhodanese...
  8. ncbi request reprint Macromolecular crowding: obvious but underappreciated
    R J Ellis
    Dept of Biological Sciences, University of Warwick, Coventry, CV4 7AL, UK
    Trends Biochem Sci 26:597-604. 2001
    ..Positive results of crowding include enhancing the collapse of polypeptide chains into functional proteins, the assembly of oligomeric structures and the efficiency of action of some molecular chaperones and metabolic pathways...
  9. pmc Assembly chaperones: a perspective
    R John Ellis
    School of Life Sciences, University of Warwick, Coventry CV4 7AL, UK
    Philos Trans R Soc Lond B Biol Sci 368:20110398. 2013
    ....
  10. ncbi request reprint The attention of researchers on the biological process of protein folding has turned to the formation and properties of aggregates
    R John Ellis
    Semin Cell Dev Biol 15:1-2. 2004
  11. ncbi request reprint Protein folding: inside the cage
    R John Ellis
    Nature 442:360-2. 2006
  12. ncbi request reprint Cell biology: join the crowd
    R John Ellis
    Nature 425:27-8. 2003
  13. ncbi request reprint Medicine: danger--misfolding proteins
    R John Ellis
    Nature 416:483-4. 2002
  14. ncbi request reprint The chaperone function: meanings and myths
    Peter A Lund
    School of Biological Sciences, University of Birmingham, Birmingham B15 2TT, UK
    Novartis Found Symp 291:23-36; discussion 36-44, 137-40. 2008
    ..The aim of this article is to provide a brief summary of the origin and concepts used in the intracellular chaperone field, to provide a backdrop for discussion of their possible roles outside the cell...