Rebecca Elliott

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. ncbi request reprint Differential response patterns in the striatum and orbitofrontal cortex to financial reward in humans: a parametric functional magnetic resonance imaging study
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester M13 9PT, United Kingdom
    J Neurosci 23:303-7. 2003
  2. doi request reprint Hedonic and informational functions of the human orbitofrontal cortex
    R Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Oxford Road, Manchester, UK
    Cereb Cortex 20:198-204. 2010
  3. ncbi request reprint Dissociable neural responses in human reward systems
    R Elliott
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London WC1N 3BG, United Kingdom
    J Neurosci 20:6159-65. 2000
  4. ncbi request reprint The neural basis of mood-congruent processing biases in depression
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, England
    Arch Gen Psychiatry 59:597-604. 2002
  5. ncbi request reprint Instrumental responding for rewards is associated with enhanced neuronal response in subcortical reward systems
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester M13 9PT, UK
    Neuroimage 21:984-90. 2004
  6. doi request reprint Medial orbitofrontal cortex codes relative rather than absolute value of financial rewards in humans
    R Elliott
    Neuroscience and Psychiatry Unit, Room G907, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Eur J Neurosci 27:2213-8. 2008
  7. doi request reprint The HTR1A and HTR1B receptor genes influence stress-related information processing
    Krisztina Mekli
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Faculty of Medical and Human Sciences, The University of Manchester, UK
    Eur Neuropsychopharmacol 21:129-39. 2011
  8. ncbi request reprint Neuronal correlates of reward and loss in Cluster B personality disorders: a functional magnetic resonance imaging study
    Birgit Völlm
    Neuroscience and Psychiatry Unit, University of Manchester, Stopford Building, Oxford Rd, Manchester M13 9PT, UK
    Psychiatry Res 156:151-67. 2007
  9. pmc Reversed frontotemporal connectivity during emotional face processing in remitted depression
    Nia Goulden
    Neuroscience and Psychiatry Unit, University of Manchester and Manchester Academic Health Sciences Centre, Manchester, United Kingdom
    Biol Psychiatry 72:604-11. 2012
  10. doi request reprint The CREB1-BDNF-NTRK2 pathway in depression: multiple gene-cognition-environment interactions
    Gabriella Juhasz
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, United Kingdom
    Biol Psychiatry 69:762-71. 2011

Collaborators

Detail Information

Publications51

  1. ncbi request reprint Differential response patterns in the striatum and orbitofrontal cortex to financial reward in humans: a parametric functional magnetic resonance imaging study
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester M13 9PT, United Kingdom
    J Neurosci 23:303-7. 2003
    ..These results suggest functional distinction in response patterns within a distributed reward system...
  2. doi request reprint Hedonic and informational functions of the human orbitofrontal cortex
    R Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Oxford Road, Manchester, UK
    Cereb Cortex 20:198-204. 2010
    ..Punishments and shift cues are associated with the same right lateral OFC focus, suggesting a fundamental connection between emotive response to negative reinforcement and use of negative information to cue behavioral change...
  3. ncbi request reprint Dissociable neural responses in human reward systems
    R Elliott
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London WC1N 3BG, United Kingdom
    J Neurosci 20:6159-65. 2000
    ..These results demonstrate dissociable neural responses to rewards and penalties that are dependent on the psychological context in which they are experienced...
  4. ncbi request reprint The neural basis of mood-congruent processing biases in depression
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, England
    Arch Gen Psychiatry 59:597-604. 2002
    ..Depressed patients show preferential processing of negatively toned stimuli across a range of cognitive tasks. The present study aimed to determine whether these behavioral abnormalities are associated with specific neural substrates...
  5. ncbi request reprint Instrumental responding for rewards is associated with enhanced neuronal response in subcortical reward systems
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester M13 9PT, UK
    Neuroimage 21:984-90. 2004
    ..The striatum and amygdala may mediate the function of rewards in eliciting goal-directed behaviour, while the orbitofrontal cortex mediates incentive value...
  6. doi request reprint Medial orbitofrontal cortex codes relative rather than absolute value of financial rewards in humans
    R Elliott
    Neuroscience and Psychiatry Unit, Room G907, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Eur J Neurosci 27:2213-8. 2008
    ....
  7. doi request reprint The HTR1A and HTR1B receptor genes influence stress-related information processing
    Krisztina Mekli
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Faculty of Medical and Human Sciences, The University of Manchester, UK
    Eur Neuropsychopharmacol 21:129-39. 2011
    ....
  8. ncbi request reprint Neuronal correlates of reward and loss in Cluster B personality disorders: a functional magnetic resonance imaging study
    Birgit Völlm
    Neuroscience and Psychiatry Unit, University of Manchester, Stopford Building, Oxford Rd, Manchester M13 9PT, UK
    Psychiatry Res 156:151-67. 2007
    ..Our results suggest dysfunctional responses to rewarding and aversive stimuli in Cluster B personality disordered individuals but do not support the notion of hypersensitivity to reward and hyposensitivity to loss...
  9. pmc Reversed frontotemporal connectivity during emotional face processing in remitted depression
    Nia Goulden
    Neuroscience and Psychiatry Unit, University of Manchester and Manchester Academic Health Sciences Centre, Manchester, United Kingdom
    Biol Psychiatry 72:604-11. 2012
    ..This suggests the problem might lie in the integrated functioning of emotion processing circuits...
  10. doi request reprint The CREB1-BDNF-NTRK2 pathway in depression: multiple gene-cognition-environment interactions
    Gabriella Juhasz
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, United Kingdom
    Biol Psychiatry 69:762-71. 2011
    ....
  11. doi request reprint The effect of acute citalopram on face emotion processing in remitted depression: a pharmacoMRI study
    Ian M Anderson
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Faculty of Medical and Human Sciences, University of Manchester, Manchester, M13 9PT, UK
    Eur Neuropsychopharmacol 21:140-8. 2011
    ....
  12. doi request reprint State-dependent alteration in face emotion recognition in depression
    Ian M Anderson
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Br J Psychiatry 198:302-8. 2011
    ..Negative biases in emotional processing are well recognised in people who are currently depressed but are less well described in those with a history of depression, where such biases may contribute to vulnerability to relapse...
  13. doi request reprint Increased amygdala responses to sad but not fearful faces in major depression: relation to mood state and pharmacological treatment
    Danilo Arnone
    Neuroscience and Psychiatry Unit and Department of Imaging Science and Biomedical Engineering, University of Manchester, Manchester, United Kingdom
    Am J Psychiatry 169:841-50. 2012
    ....
  14. pmc Risk-taking behavior in a gambling task associated with variations in the tryptophan hydroxylase 2 gene: relevance to psychiatric disorders
    Gabriella Juhasz
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, UK
    Neuropsychopharmacology 35:1109-19. 2010
    ..In conclusion, our study demonstrates the role of the TPH2 gene and the serotonin system in risk taking and suggests that TPH2 gene may contribute to the expression of psychiatric phenotypes through altered decision making...
  15. doi request reprint Reduced medial prefrontal responses to social interaction images in remitted depression
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, England
    Arch Gen Psychiatry 69:37-45. 2012
    ..Stimuli with social context represent a distinct class of emotional stimuli, which in healthy volunteers are associated with specific neural substrates but have not previously been studied relative to vulnerability to depression...
  16. ncbi request reprint Neuronal correlates of theory of mind and empathy: a functional magnetic resonance imaging study in a nonverbal task
    Birgit A Vollm
    Neuroscience and Psychiatry Unit, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Neuroimage 29:90-8. 2006
    ..These results have implications for our understanding of disorders characterized by impairments of social cognition, such as autism and psychopathy...
  17. pmc Affective cognition and its disruption in mood disorders
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, University of Manchester, Manchester, UK
    Neuropsychopharmacology 36:153-82. 2011
    ..The final section presents an overview of this literature and considers implications for understanding the pathophysiology of mood disorder as well as developing and evaluating new treatment strategies...
  18. ncbi request reprint Citalopram modulation of neuronal responses to aversive face emotions: a functional MRI study
    Ian M Anderson
    Neuroscience and Psychiatry Unit, The University of Manchester, Stopford Building, Oxford Road, Manchester, UK
    Neuroreport 18:1351-5. 2007
    ..No citalopram modulation of BOLD responses to angry faces were found. These results suggest that serotonin modulates low-level amygdala activation to aversive stimuli...
  19. ncbi request reprint Abnormal ventral frontal response during performance of an affective go/no go task in patients with mania
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, United Kingdom
    Biol Psychiatry 55:1163-70. 2004
    ..The aim of this study was to investigate the neuronal basis of the bias toward positive information in manic patients...
  20. doi request reprint Mirtazapine antagonises the subjective, hormonal and neuronal effects of m-chlorophenylpiperazine (mCPP) infusion: a pharmacological-challenge fMRI (phMRI) study
    Shane McKie
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, UK
    Neuroimage 58:497-507. 2011
    ..The results suggest that mCPP-challenge phMRI produces reliable patterns of response that are mediated by 5-HT(2C) receptors; these responses may therefore be useful in-vivo measures of 5-HT(2C) function in psychiatric disorders...
  21. ncbi request reprint Serotonergic modulation of neuronal responses to behavioural inhibition and reinforcing stimuli: an fMRI study in healthy volunteers
    Birgit Völlm
    Neuroscience and Psychiatry Unit, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Eur J Neurosci 23:552-60. 2006
    ..Combining drug challenge with fMRI (pharmacoMRI; pMRI) is a promising tool for investigating these processes in healthy as well as patient groups...
  22. doi request reprint Sample size estimation for comparing parameters using dynamic causal modeling
    Nia Goulden
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, United Kingdom
    Brain Connect 2:80-90. 2012
    ..Due to variability between task, volunteers, scanner, and acquisition parameters, this would need to be evaluated on individual datasets. This approach will be a useful guide for Dynamic Causal Modeling studies...
  23. doi request reprint Co-operation with another player in a financially rewarded guessing game activates regions implicated in theory of mind
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, UK
    Soc Neurosci 1:385-95. 2006
    ..Critically the response to reward in medial orbitofrontal cortex was significantly enhanced when subjects were co-operating. This suggests that rewards achieved through co-operation are more valuable than rewards achieved alone...
  24. doi request reprint A comparison of permutation and parametric testing for between group effective connectivity differences using DCM
    Nia Goulden
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, UK
    Neuroimage 50:509-15. 2010
    ..Permutation testing was found to provide superior power compared with the nonparametric equivalent...
  25. doi request reprint Detection of the acute effects of hydrocortisone in the hippocampus using pharmacological fMRI
    Catherine S Symonds
    Neuroscience and Psychiatry Unit, The University of Manchester and Manchester Academic Health Sciences Centre, Manchester, United Kingdom
    Eur Neuropsychopharmacol 22:867-74. 2012
    ..Hydrocortisone infusion phMRI may be a useful tool to investigate hippocampal corticosteroid receptor function in depression...
  26. doi request reprint Increased amygdala response to shame in remitted major depressive disorder
    Erdem Pulcu
    The University of Manchester and Manchester Academic Health Sciences Centre, School of Medicine, Neuroscience and Psychiatry Unit, Manchester, United Kingdom
    PLoS ONE 9:e86900. 2014
    ..Shame-induction may be a more sensitive probe of residual amygdala hypersensitivity in MDD compared with facial emotion-evoked responses previously found to normalize on remission. ..
  27. doi request reprint Dopaminergic influences on executive function and impulsive behaviour in impulse control disorders in Parkinson's disease
    Iracema Leroi
    Institute of Brain, Behaviour and Mental Health, University of Manchester, UK Manchester Mental Health and Social Care Trust, Manchester, UK
    J Neuropsychol 7:306-25. 2013
    ..Both pharmacologic and genotypic influences on dopaminergic state may be important in ICD. ..
  28. doi request reprint A functional magnetic resonance imaging paradigm of expressed emotion in schizophrenia
    Angela J Rylands
    Department of Clinical Psychology, School of Psychological Sciences, University of Manchester, Manchester, United Kingdom
    J Nerv Ment Dis 199:25-9. 2011
    ..Such a pattern of neural response may represent a putative neural network responsible for mediating High EE in schizophrenia...
  29. doi request reprint Diminished neural and cognitive responses to facial expressions of disgust in patients with psoriasis: a functional magnetic resonance imaging study
    C Elise Kleyn
    Dermatological Sciences, The University of Manchester, Manchester, UK
    J Invest Dermatol 129:2613-9. 2009
    ..We hypothesize that patients with psoriasis, in this case male patients, develop a coping mechanism to protect them from stressful emotional responses by blocking the processing of disgusted facial expressions...
  30. ncbi request reprint Attention to pain localization and unpleasantness discriminates the functions of the medial and lateral pain systems
    B Kulkarni
    Human Pain Research Group, Clinical Sciences Building, Hope Hospital, Salford, M6 8HD, UK
    Eur J Neurosci 21:3133-42. 2005
    ..They also provide the first clear demonstration, within a single experiment, of a major division of function within the neural pain matrix...
  31. pmc Long term clinical outcome of home and hospital intravenous antibiotic treatment in adults with cystic fibrosis
    J Thornton
    School of Pharmacy and Pharmaceutical Sciences, University of Manchester M13 9PL, UK
    Thorax 59:242-6. 2004
    ....
  32. ncbi request reprint Role of the orbitofrontal cortex in reinforcement processing and inhibitory control: evidence from functional magnetic resonance imaging studies in healthy human subjects
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, United Kingdom
    Int Rev Neurobiol 65:89-116. 2005
  33. doi request reprint The neural basis of maternal bonding
    Ming Wai Wan
    Centre for Women s Mental Health, Institute of Brain, Behaviour and Mental Health, University of Manchester, Manchester, United Kingdom
    PLoS ONE 9:e88436. 2014
    ..We examined the brain regions activated when mothers viewed videos of their own infant contrasted with an unknown infant, and whether these are associated with behavioural and self-reported measures of mother-infant relations...
  34. doi request reprint Empathy, ToM, and self-other differentiation: an fMRI study of internal states
    Renate L E P Reniers
    a Neuroscience and Psychiatry Unit, University of Manchester, Manchester, UK
    Soc Neurosci 9:50-62. 2014
    ....
  35. ncbi request reprint Neurobiological substrates of antisocial and borderline personality disorder: preliminary results of a functional fMRI study
    Birgit Völlm
    Neuroscience and Psychiatry Unit, University of Manchester
    Crim Behav Ment Health 14:39-54. 2004
    ..In normal subjects functional brain imaging has been used to investigate the neuroanatomy of impulse control. There are no such imaging studies in personality-disordered populations...
  36. ncbi request reprint Response inhibition and impulsivity: an fMRI study
    N R Horn
    Neuroscience and Psychiatry Unit, University of Manchester, Stopford Building, Oxford Road, M13 9PT, Manchester, UK
    Neuropsychologia 41:1959-66. 2003
    ..It may also allow study of the effects of physical and psychological interventions on response inhibition in clinical conditions such as antisocial personality disorder...
  37. pmc The role of self-blaming moral emotions in major depression and their impact on social-economical decision making
    Erdem Pulcu
    Neuroscience and Psychiatry Unit, Manchester Academic Health Sciences Centre, School of Medicine, The University of Manchester, Manchester, UK
    Front Psychol 4:310. 2013
    ....
  38. doi request reprint Apathy and impulse control disorders in Parkinson's disease: a direct comparison
    Iracema Leroi
    University of Manchester, UK
    Parkinsonism Relat Disord 18:198-203. 2012
    ..Apathy and impulse control disorders (ICDs) in Parkinson's disease (PD) are clinically important complications and may exist on a common behavioral spectrum of disorders of reward and motivation...
  39. ncbi request reprint Executive functions and their disorders
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, UK
    Br Med Bull 65:49-59. 2003
    ....
  40. doi request reprint CNR1 gene is associated with high neuroticism and low agreeableness and interacts with recent negative life events to predict current depressive symptoms
    Gabriella Juhasz
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK
    Neuropsychopharmacology 34:2019-27. 2009
    ..This study also suggests that the CNR1 gene influences vulnerability to recent psychosocial adversity to produce current symptoms of depression...
  41. ncbi request reprint Prediction error for free monetary reward in the human prefrontal cortex
    N Ramnani
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, London, UK
    Neuroimage 23:777-86. 2004
    ..Activity time-locked to prediction errors in frontotemporal circuits suggests that they are involved in encoding the associations between visual cues and monetary rewards in the human brain...
  42. ncbi request reprint Lack of behavioural effects after acute tyrosine depletion in healthy volunteers
    K E Lythe
    Neuroscience and Psychiatry Unit, School of Psychiatry and Behavioural Sciences, Manchester, UK
    J Psychopharmacol 19:5-11. 2005
    ..Our results are consistent with acute dietary tyrosine depletion causing a reduction in brain dopamine neurotransmission but raise questions about how robust or consistent the effects are on psychological function...
  43. ncbi request reprint Ventromedial prefrontal cortex mediates guessing
    R Elliott
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
    Neuropsychologia 37:403-11. 1999
    ..This region is not typically activated in working memory tasks and its activation may reflect additional requirements of dealing with uncertainty...
  44. ncbi request reprint Differential neural response to positive and negative feedback in planning and guessing tasks
    R Elliott
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London, U K
    Neuropsychologia 35:1395-404. 1997
    ....
  45. ncbi request reprint Neuronal effects of acute citalopram detected by pharmacoMRI
    S McKie
    Neuroscience and Psychiatry Unit, The University of Manchester, Manchester, UK
    Psychopharmacology (Berl) 180:680-6. 2005
    ..Serotonin (5-hydroxytryptamine, 5-HT) is implicated in the aetiology and treatment of a variety of psychiatric disorders. A limitation of research has been the necessity to use indirect measures of 5-HT function...
  46. ncbi request reprint Neural activity relating to generation and representation of galvanic skin conductance responses: a functional magnetic resonance imaging study
    H D Critchley
    Wellcome Department of Cognitive Neurology, London WC1N 3BG, United Kingdom
    J Neurosci 20:3033-40. 2000
    ..We propose that this functional arrangement enables integration of adaptive bodily responses with ongoing emotional and attentional states of the organism...
  47. ncbi request reprint 5-HT(2C) receptor activation by m-chlorophenylpiperazine detected in humans with fMRI
    I M Anderson
    Neuroscience and Psychiatry Unit, The University of Manchester, UK
    Neuroreport 13:1547-51. 2002
    ..05 small volume corrected). These findings suggest that pharmacoMRI is a potentially powerful tool for investigating neurotransmitter function in humans...
  48. doi request reprint Assessing human 5-HT function in vivo with pharmacoMRI
    I M Anderson
    Neuroscience and Psychiatry Unit, The University of Manchester, Room G907, Stopford Building, Oxford Road, Manchester M13 9PT, United Kingdom
    Neuropharmacology 55:1029-37. 2008
    ..If this is successful then phMRI will provide a genuinely exciting opportunity for the rapid development of better treatments for psychiatric conditions...
  49. ncbi request reprint The effect of citalopram pretreatment on neuronal responses to neuropsychological tasks in normal volunteers: an FMRI study
    Cristina M Del-Ben
    Faculty of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil
    Neuropsychopharmacology 30:1724-34. 2005
    ..The technique of combining drug challenge with fMRI (pharmacoMRI) has promise for investigating human psychiatric disorders...
  50. ncbi request reprint The neural response to emotional prosody, as revealed by functional magnetic resonance imaging
    Rachel L C Mitchell
    Whiteknights Road, School of Psychology, University of Reading, Reading, RG6 6AL, Berkshire, UK
    Neuropsychologia 41:1410-21. 2003
    ..In confirming the results of lesion and neuropsychological studies, the current study emphasises the importance of the right hemisphere in the processing of emotional prosody, specifically the lateral temporal lobes...
  51. ncbi request reprint Neural response to emotional prosody in schizophrenia and in bipolar affective disorder
    Rachel L C Mitchell
    School of Psychology, University of Reading, and Neuroscience and Emotion Section, Institute of Psychiatry, London
    Br J Psychiatry 184:223-30. 2004
    ..Evidence suggests a reversal of the normal left-lateralised response to speech in schizophrenia...