Ulf Ekelund

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi Accelerometers and pedometers: methodology and clinical application
    Kirsten Corder
    Medical Research Council Epidemiology Unit, Cambridge, UK
    Curr Opin Clin Nutr Metab Care 10:597-603. 2007
  2. pmc Correlates of objectively assessed physical activity and sedentary time in children: a cross-sectional study (The European Youth Heart Study)
    Andreas Nilsson
    School of Health and Medical Sciences, Orebro University, Orebro, Sweden
    BMC Public Health 9:322. 2009
  3. pmc The ProActive trial protocol - a randomised controlled trial of the efficacy of a family-based, domiciliary intervention programme to increase physical activity among individuals at high risk of diabetes [ISRCTN61323766]
    Kate Williams
    General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, Institute of Public Health, Forvie Site, Robinson Way, Cambridge CB2 2SR, UK
    BMC Public Health 4:48. 2004
  4. pmc Randomized controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial
    Francis M Finucane
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    BMC Endocr Disord 9:15. 2009
  5. ncbi Body movement and physical activity energy expenditure in children and adolescents: how to adjust for differences in body size and age
    Ulf Ekelund
    MRC Epidemiology Unit, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, United Kingdom
    Am J Clin Nutr 79:851-6. 2004
  6. ncbi Associations between objectively assessed physical activity and indicators of body fatness in 9- to 10-y-old European children: a population-based study from 4 distinct regions in Europe (the European Youth Heart Study)
    Ulf Ekelund
    MRC Epidemiology Unit, Strangeways Research Laboratories, Wort s Causeway, Cambridge CB1 8RN, United Kingdom
    Am J Clin Nutr 80:584-90. 2004
  7. ncbi Associations between physical activity and fat mass in adolescents: the Stockholm Weight Development Study
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Am J Clin Nutr 81:355-60. 2005
  8. doi Prevalence and correlates of the metabolic syndrome in a population-based sample of European youth
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, UK
    Am J Clin Nutr 89:90-6. 2009
  9. ncbi Physical activity energy expenditure predicts progression toward the metabolic syndrome independently of aerobic fitness in middle-aged healthy Caucasians: the Medical Research Council Ely Study
    Ulf Ekelund
    Epidemiology Unit, Medical Research Council, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, U K
    Diabetes Care 28:1195-200. 2005
  10. ncbi Physical activity energy expenditure predicts changes in body composition in middle-aged healthy whites: effect modification by age
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Am J Clin Nutr 81:964-9. 2005

Detail Information

Publications120 found, 100 shown here

  1. ncbi Accelerometers and pedometers: methodology and clinical application
    Kirsten Corder
    Medical Research Council Epidemiology Unit, Cambridge, UK
    Curr Opin Clin Nutr Metab Care 10:597-603. 2007
    ..Recommendations are given for the use of movement sensors during free-living conditions and methods of data analysis and interpretation are discussed...
  2. pmc Correlates of objectively assessed physical activity and sedentary time in children: a cross-sectional study (The European Youth Heart Study)
    Andreas Nilsson
    School of Health and Medical Sciences, Orebro University, Orebro, Sweden
    BMC Public Health 9:322. 2009
    ....
  3. pmc The ProActive trial protocol - a randomised controlled trial of the efficacy of a family-based, domiciliary intervention programme to increase physical activity among individuals at high risk of diabetes [ISRCTN61323766]
    Kate Williams
    General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, Institute of Public Health, Forvie Site, Robinson Way, Cambridge CB2 2SR, UK
    BMC Public Health 4:48. 2004
    ..While previous evaluations of interventions to increase physical activity have involved communities or individuals with established disease, less attention has been given to interventions for individuals at risk of disease...
  4. pmc Randomized controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial
    Francis M Finucane
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    BMC Endocr Disord 9:15. 2009
    ..TRIAL REGISTRATION: Current Controlled Trials: ISRCTN60986572...
  5. ncbi Body movement and physical activity energy expenditure in children and adolescents: how to adjust for differences in body size and age
    Ulf Ekelund
    MRC Epidemiology Unit, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, United Kingdom
    Am J Clin Nutr 79:851-6. 2004
    ..Physical activity data in children and adolescents who differ in body size and age are influenced by whether physical activity is expressed in terms of body movement or energy expenditure...
  6. ncbi Associations between objectively assessed physical activity and indicators of body fatness in 9- to 10-y-old European children: a population-based study from 4 distinct regions in Europe (the European Youth Heart Study)
    Ulf Ekelund
    MRC Epidemiology Unit, Strangeways Research Laboratories, Wort s Causeway, Cambridge CB1 8RN, United Kingdom
    Am J Clin Nutr 80:584-90. 2004
    ..The rising prevalence of obesity in children may be due to a reduction in physical activity (PA)...
  7. ncbi Associations between physical activity and fat mass in adolescents: the Stockholm Weight Development Study
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Am J Clin Nutr 81:355-60. 2005
    ..Obesity is multifactorial. However, the accumulation of fat mass (FM) is proposed to be due to a positive energy balance, which may be caused by reduced physical activity (PA)...
  8. doi Prevalence and correlates of the metabolic syndrome in a population-based sample of European youth
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, UK
    Am J Clin Nutr 89:90-6. 2009
    ..Until recently, there has been no unified definition of the metabolic syndrome (MetS) in the youth. Therefore, the prevalence of MetS and its association with potential correlates are largely unknown...
  9. ncbi Physical activity energy expenditure predicts progression toward the metabolic syndrome independently of aerobic fitness in middle-aged healthy Caucasians: the Medical Research Council Ely Study
    Ulf Ekelund
    Epidemiology Unit, Medical Research Council, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, U K
    Diabetes Care 28:1195-200. 2005
    ....
  10. ncbi Physical activity energy expenditure predicts changes in body composition in middle-aged healthy whites: effect modification by age
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Am J Clin Nutr 81:964-9. 2005
    ..It is unclear whether physical activity energy expenditure (PAEE) predicts changes in body composition...
  11. ncbi Association of weight gain in infancy and early childhood with metabolic risk in young adults
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge CB1 9NL, United Kingdom
    J Clin Endocrinol Metab 92:98-103. 2007
    ..Early postnatal life has been suggested as an important window during which risks for long-term health may be influenced...
  12. ncbi Oxygen uptakes adjusted for body composition in normal-weight and obese adolescents
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Obes Res 12:513-20. 2004
    ....
  13. ncbi Upward weight percentile crossing in infancy and early childhood independently predicts fat mass in young adults: the Stockholm Weight Development Study (SWEDES)
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Am J Clin Nutr 83:324-30. 2006
    ..Rapid early postnatal weight gain predicts increased subsequent obesity and related disease risks. However, the exact timing of adverse rapid postnatal weight gain is unclear...
  14. ncbi Is the ArteACC index a valid indicator of free-living physical activity in adolescents?
    Ulf Ekelund
    Diabetes Research Group, Institute of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
    Obes Res 11:793-801. 2003
    ..A secondary aim was to develop regression equations for prediction of total energy expenditure (TEE) and activity energy expenditure [AEE = 0.9 x TEE - resting metabolic rate (RMR)]...
  15. pmc Objectively measured moderate- and vigorous-intensity physical activity but not sedentary time predicts insulin resistance in high-risk individuals
    Ulf Ekelund
    Medical Research Council, Epidemiology Unit, Cambridge, UK
    Diabetes Care 32:1081-6. 2009
    ....
  16. doi Targeting sedentary time or moderate- and vigorous-intensity activity: independent relations with adiposity in a population-based sample of 10-y-old British children
    Rebekah M Steele
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Am J Clin Nutr 90:1185-92. 2009
    ..It is unclear whether subcomponents of physical activity (PA) are associated with adiposity independent of time spent while sedentary...
  17. ncbi Prediction of childhood obesity by infancy weight gain: an individual-level meta-analysis
    Celine Druet
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Paediatr Perinat Epidemiol 26:19-26. 2012
    ..A risk score combining birthweight and infant weight gain (or simply infant weight), together with mother's body mass index and sex may allow early stratification of infants at risk of childhood obesity...
  18. ncbi Does the association of habitual physical activity with the metabolic syndrome differ by level of cardiorespiratory fitness?
    Paul W Franks
    MRC Epidemiology Unit, Cambridge, UK
    Diabetes Care 27:1187-93. 2004
    ..The purpose of this study was, therefore, to describe the association between physical activity and the metabolic syndrome and to test whether fitness level modifies this relationship...
  19. doi Television viewing time independently predicts all-cause and cardiovascular mortality: the EPIC Norfolk study
    Katrien Wijndaele
    MRC Epidemiology Unit, Cambridge, UK
    Int J Epidemiol 40:150-9. 2011
    ..Television viewing (TV), a highly prevalent behaviour, is associated with higher cardiovascular risk independently of physical activity. The relationship with mortality, however, is relatively unknown...
  20. doi Breakfast consumption and physical activity in adolescents: daily associations and hourly patterns
    Kirsten Corder
    UK Clinical Research Collaboration Centre for Diet and Activity Research KC and EMFvS, Medical Research Council MRC Epidemiology Unit KC, CLR, RMS, EMFvS, and UE, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, United Kingdom the MRC Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, United Kingdom CJP and AMS the Developmental Psychiatry Section, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom DJB, VJD, and IMG and the Department of Sports Medicine, Norwegian School of Sports Sciences, Oslo, Norway UE
    Am J Clin Nutr 99:361-8. 2014
    ..The association between breakfast consumption and physical activity (PA) is inconclusive...
  21. pmc Determinants of change in children's sedentary time
    Andrew J Atkin
    UKCRC Centre for Diet and Activity Research, Institute of Public Health, Cambridge, United Kingdom
    PLoS ONE 8:e67627. 2013
    ..Understanding the determinants of sedentary time during childhood contributes to the development of effective intervention programmes...
  22. pmc Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study
    Clara Kelliny
    Medical Research Council Epidemiology Unit, Addenbrooke s Hospital, Institute of Metabolic Science, Cambridge, U K
    Diabetes 58:2939-45. 2009
    ..The goal of this study was to investigate whether the effects of common genetic variants associated with fasting glucose in adults are detectable in healthy children...
  23. doi Absence of association between the INSIG2 gene polymorphism (rs7566605) and obesity in the European Youth Heart Study (EYHS)
    Karani S Vimaleswaran
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Obesity (Silver Spring) 17:1453-7. 2009
    ..There was also no evidence of interaction between genotype and physical activity (P = 0.95). Despite an adequately powered study, our findings suggest that rs7566605 is not associated with obesity-related traits and lipids in the EYHS...
  24. ncbi Time spent being sedentary and weight gain in healthy adults: reverse or bidirectional causality?
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 88:612-7. 2008
    ..Whether obesity is a cause or a consequence of a sedentary lifestyle has not yet been fully elucidated, which leaves uncertainty about the direction of causality...
  25. pmc Habitual energy expenditure modifies the association between NOS3 gene polymorphisms and blood pressure
    Karani S Vimaleswaran
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Am J Hypertens 21:297-302. 2008
    ..Thus, energy expenditure may modify the association between the genetic variation at NOS3 and blood pressure...
  26. pmc Television viewing and incident cardiovascular disease: prospective associations and mediation analysis in the EPIC Norfolk Study
    Katrien Wijndaele
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    PLoS ONE 6:e20058. 2011
    ..This study examined whether television viewing time is associated with these three outcomes, independently of physical activity energy expenditure and other confounding variables...
  27. doi Estimating physical activity energy expenditure, sedentary time, and physical activity intensity by self-report in adults
    Herve Besson
    Medical Research Council, Epidemiology Unit, Cambridge, UK
    Am J Clin Nutr 91:106-14. 2010
    ..Few questionnaires that assess usual physical activity have been reported to be valid for all different subdimensions of physical activity...
  28. pmc Genetic variation in LIN28B is associated with the timing of puberty
    Ken K Ong
    Medical Research Council MRC Epidemiology Unit, Addenbrooke s Hospital, Cambridge, UK
    Nat Genet 41:729-33. 2009
    ..These studies identify variation in LIN28B, a potent and specific regulator of microRNA processing, as the first genetic determinant regulating the timing of human pubertal growth and development...
  29. pmc Objectively measured sedentary time may predict insulin resistance independent of moderate- and vigorous-intensity physical activity
    Hendrik J F Helmerhorst
    Medical Research Council Epidemiology Unit, Cambridge, UK
    Diabetes 58:1776-9. 2009
    ....
  30. pmc TV viewing and physical activity are independently associated with metabolic risk in children: the European Youth Heart Study
    Ulf Ekelund
    Epidemiology Unit, Medical Research Council, Cambridge, United Kingdom
    PLoS Med 3:e488. 2006
    ..TV viewing has been linked to metabolic-risk factors in youth. However, it is unclear whether this association is independent of physical activity (PA) and obesity...
  31. doi Physical activity attenuates the body mass index-increasing influence of genetic variation in the FTO gene
    Karani S Vimaleswaran
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom
    Am J Clin Nutr 90:425-8. 2009
    ..Intronic variation in the FTO (fat mass and obesity-associated) gene has been unequivocally associated with increased body mass index (BMI; in kg/m(2)) and the risk of obesity in populations of different ethnicity...
  32. pmc Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies
    Marcel den Hoed
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Diabetes 59:2980-8. 2010
    ..We examined associations of variants in these loci with anthropometric traits in children and adolescents...
  33. doi Relationship between subdomains of total physical activity and mortality
    Herve Besson
    Epidemiology Unit, Medical Research Council, Cambridge, United Kingdom
    Med Sci Sports Exerc 40:1909-15. 2008
    ..However, it is unclear how this association varies according to the domain of life in which the activity takes place...
  34. ncbi Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals
    Tuomas O Kilpeläinen
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 93:851-60. 2011
    ..High birth weight is associated with adult body mass index (BMI). We hypothesized that birth weight and BMI may partly share a common genetic background...
  35. ncbi Hierarchy of individual calibration levels for heart rate and accelerometry to measure physical activity
    Søren Brage
    MRC Epidemiology Unit, Cambridge CB1 9NL, UK
    J Appl Physiol (1985) 103:682-92. 2007
    ..In conclusion, a substantial proportion of the between-individual variance in relationships between PAI, accelerometry, and HR is captured with simple calibration procedures, feasible for use in epidemiological studies...
  36. pmc Urbanization, physical activity, and metabolic health in sub-Saharan Africa
    Felix K Assah
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Diabetes Care 34:491-6. 2011
    ..We examined the independent associations between objectively measured free-living physical activity energy expenditure (PAEE) and the metabolic syndrome in adults in rural and urban Cameroon...
  37. ncbi Increase in physical activity energy expenditure is associated with reduced metabolic risk independent of change in fatness and fitness
    Ulf Ekelund
    MRC Epidemiology Unit, Elsie Widdowson Laboratory, Fulbourne Road, CB1 9NL, Cambridge, U K
    Diabetes Care 30:2101-6. 2007
    ..We sought to examine whether change in physical activity energy expenditure (PAEE) is associated with change in metabolic risk factors and whether this association is independent of change in fat mass and aerobic fitness...
  38. ncbi Comparison of two methods to assess PAEE during six activities in children
    Kirsten Corder
    1MRC Epidemiology Unit, Cambridge, United Kingdom
    Med Sci Sports Exerc 39:2180-8. 2007
    ..Three PAEE-prediction models derived using the current data, and five previously published prediction models were cross-validated to estimate PAEE in this sample...
  39. ncbi Obesity is associated with altered lung function independently of physical activity and fitness
    Rebekah M Steele
    Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Obesity (Silver Spring) 17:578-84. 2009
    ..These associations were independent of the degree of physical activity and aerobic fitness in this cohort...
  40. doi Physical activity energy expenditure of adolescents in India
    Kirsten Corder
    MRC Epidemiology Unit, Institute of Metabolic Science, Box 285 Addenbrooke s Hospital, Cambridge, UK
    Obesity (Silver Spring) 18:2212-9. 2010
    ..Further research is necessary to investigate the association between PA and health outcomes in Indian adolescents...
  41. pmc Separating movement and gravity components in an acceleration signal and implications for the assessment of human daily physical activity
    Vincent T van Hees
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    PLoS ONE 8:e61691. 2013
    ....
  42. pmc Is wearing a pedometer associated with higher physical activity among adolescents?
    Vanda Ho
    Murray Edwards College, Huntingdon Road, Cambridge, United Kingdom
    Prev Med 56:273-7. 2013
    ..To examine whether wearing a pedometer was associated with higher objectively-measured physical activity (PA) among adolescents independent of other behavior change strategies, and whether this association differed by sex or day of wear...
  43. pmc Physical activity intensity, sedentary time, and body composition in preschoolers
    Paul J Collings
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 97:1020-8. 2013
    ..Detailed associations between physical activity (PA) subcomponents, sedentary time, and body composition in preschoolers remain unclear...
  44. pmc Predicting physical activity energy expenditure using accelerometry in adults from sub-Sahara Africa
    Felix K Assah
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Obesity (Silver Spring) 17:1588-95. 2009
    ..Accelerometry could be used to predict PAEE in this population and, therefore, has important applications for monitoring population levels of total physical activity patterns...
  45. doi Birth size, infant weight gain, and motor development influence adult physical performance
    Charlotte L Ridgway
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Med Sci Sports Exerc 41:1212-21. 2009
    ....
  46. ncbi Effect of combined movement and heart rate monitor placement on physical activity estimates during treadmill locomotion and free-living
    Søren Brage
    MRC Epidemiology Unit, Institute of Public Health, University of Cambridge, Elsie Widdowson Laboratory, Fulbourn Road, CB1 9NL, Cambridge, United Kingdom
    Eur J Appl Physiol 96:517-24. 2006
    ..Regardless of which position is used, this has little or no effect on movement counts and energy expenditure estimates, which is encouraging for studies where research participants may have to position the monitors themselves...
  47. doi Lack of association between PCK1 polymorphisms and obesity, physical activity, and fitness in European Youth Heart Study (EYHS)
    Karani S Vimaleswaran
    Institute of Metabolic Science, MRC Epidemiology Unit, Cambridge, UK
    Obesity (Silver Spring) 18:1975-80. 2010
    ..Despite strong evidence from animal studies, our study in the EYHS cohort failed to identify an association of PCK1 polymorphisms with obesity, PA, and fitness...
  48. doi Accuracy and validity of a combined heart rate and motion sensor for the measurement of free-living physical activity energy expenditure in adults in Cameroon
    Felix K Assah
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Int J Epidemiol 40:112-20. 2011
    ..We examined the validity of a combined HR and motion sensor in estimating physical activity energy expenditure (PAEE) in free-living adults in rural and urban Cameroon compared with doubly-labelled water (DLW) as criterion...
  49. ncbi Activity levels in mothers and their preschool children
    Kathryn R Hesketh
    UK Clinical Research Collaboration Centre of Excellence for Diet and Activity Research, Institute of Public Health, University of Cambridge, Cambridge, United Kingdom
    Pediatrics 133:e973-80. 2014
    ....
  50. doi Sedentary time in children: influence of accelerometer processing on health relations
    Andrew J Atkin
    UKCRC Centre for Diet and Activity Research CEDAR, Cambridge, United Kingdom
    Med Sci Sports Exerc 45:1097-104. 2013
    ..This cross-sectional study examined the influence of selected accelerometer cut points and nonwear criteria on associations of sedentary time with adiposity and clustered metabolic risk...
  51. pmc Heritability of objectively assessed daily physical activity and sedentary behavior
    Marcel den Hoed
    Medical Research Council Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, United Kingdom MdH, SB, JHZ, KW, UE, NJW, and RJFL the Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden MdH the Department of Twin Research and Genetic Epidemiology Unit, St Thomas Campus, King s College London, St Thomas Hospital, London, United Kingdom AN and TDS the Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway UE and The Charles Bronfman Institute for Personalized Medicine RJFL, The Mindich Child Health and Development Institute RJFL, and The Genetics of Obesity and Related Metabolic Traits Program RJFL, The Icahn School of Medicine at Sinai School, New York, NY
    Am J Clin Nutr 98:1317-25. 2013
    ..Twin and family studies that estimated the heritability of daily physical activity have been limited by poor measurement quality and a small sample size...
  52. pmc Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children
    Tuomas O Kilpeläinen
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    PLoS Med 8:e1001116. 2011
    ..To confirm or refute unambiguously whether PA attenuates the association of FTO with obesity risk, we meta-analyzed data from 45 studies of adults (n = 218,166) and nine studies of children and adolescents (n = 19,268)...
  53. pmc Free-living physical activity energy expenditure is strongly related to glucose intolerance in Cameroonian adults independently of obesity
    Felix K Assah
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Diabetes Care 32:367-9. 2009
    ..We examined the cross-sectional association between objectively measured free-living physical activity energy expenditure (PAEE) and glucose tolerance in adult Cameroonians without known diabetes...
  54. pmc Do physical activity and aerobic fitness moderate the association between birth weight and metabolic risk in youth?: the European Youth Heart Study
    Charlotte L Ridgway
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Diabetes Care 34:187-92. 2011
    ..Lower birth weight has been associated with a greater risk of metabolic diseases. The aim of this study was examine whether physical activity and aerobic fitness may modify associations between birth weigh and metabolic risk...
  55. ncbi Multiple behaviour change intervention and outcomes in recently diagnosed type 2 diabetes: the ADDITION-Plus randomised controlled trial
    Simon J Griffin
    MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK
    Diabetologia 57:1308-19. 2014
    ....
  56. doi Objectively measured physical activity in four-year-old British children: a cross-sectional analysis of activity patterns segmented across the day
    Kathryn R Hesketh
    UKCRC Centre of Excellence for Diet and Activity Research CEDAR, Box 296, Institute of Public Health, University of Cambridge, Cambridge, UK
    Int J Behav Nutr Phys Act 11:1. 2014
    ..Little is known about preschool-aged children's levels of physical activity (PA) over the course of the day. Using time-stamped data, we describe the levels and patterns of PA in a population-based sample of four-year-old British children...
  57. pmc A systematic review of reliability and objective criterion-related validity of physical activity questionnaires
    Hendrik J F Helmerhorst
    Medical Research Council Epidemiology Unit, Cambridge, UK
    Int J Behav Nutr Phys Act 9:103. 2012
    ..Newly developed PAQs do not appear to perform substantially better than existing PAQs in terms of reliability and validity. Future PAQ studies should include measures of absolute validity and the error structure of the instrument...
  58. ncbi Physical activity and metabolic risk in individuals with a family history of type 2 diabetes
    Ulf Ekelund
    MRC Epidemiology Unit, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, U K
    Diabetes Care 30:337-42. 2007
    ....
  59. ncbi Association between birth weight and visceral fat in adults
    Emanuella De Lucia Rolfe
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 92:347-52. 2010
    ..Several studies reported inverse associations between birth weight and central adiposity in adults. However, few studies investigated the contributions of different abdominal fat compartments...
  60. pmc Protocol for the ADDITION-Plus study: a randomised controlled trial of an individually-tailored behaviour change intervention among people with recently diagnosed type 2 diabetes under intensive UK general practice care
    Simon J Griffin
    MRC Epidemiology Unit, Box 285, Addenbrooke s Hospital, Hills Road, Cambridge, CB2 0QQ, UK
    BMC Public Health 11:211. 2011
    ..The ADDITION-Plus trial was designed to address these issues among recently diagnosed patients in primary care over one year...
  61. pmc Does birth weight influence physical activity in youth? A combined analysis of four studies using objectively measured physical activity
    Charlotte L Ridgway
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    PLoS ONE 6:e16125. 2011
    ..Overall this combined analysis suggests that birth weight may not be an important biological determinant of habitual physical activity or sedentary behaviour in children and adolescents...
  62. pmc Physical activity, cardiorespiratory fitness, and the metabolic syndrome in youth
    Rebekah M Steele
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke s Hospital, Hills Rd, Cambridge CB2 0QQ, UK
    J Appl Physiol (1985) 105:342-51. 2008
    ..Public health approaches that encourage increased physical activity and reduce sedentary behaviors may prove useful in reducing the population burden associated with metabolic risk...
  63. doi Changes in children's physical activity over 12 months: longitudinal results from the SPEEDY study
    Kirsten Corder
    MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke s Hospital, Hills Road, Cambridge, CB2 0QQ, United Kingdom
    Pediatrics 126:e926-35. 2010
    ..We measured physical activity changes among 10-year-old British children over 12 months and assessed biological and demographic determinants...
  64. ncbi Comparison of two Actigraph models for assessing free-living physical activity in Indian adolescents
    Kirsten Corder
    MRC Epidemiology Unit, Institute of Metabolic Science, Box 285 Addenbrooke s Hospital, Cambridge CB2 0QQ, UK
    J Sports Sci 25:1607-11. 2007
    ....
  65. pmc Impact of study design on development and evaluation of an activity-type classifier
    Vincent T van Hees
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    J Appl Physiol (1985) 114:1042-51. 2013
    ..Future studies that aim to evaluate activity classification methods are warranted to pay special attention to the representativeness of experimental conditions for real-life conditions...
  66. ncbi Comparison of PAEE from combined and separate heart rate and movement models in children
    Kirsten Corder
    Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom
    Med Sci Sports Exerc 37:1761-7. 2005
    ....
  67. doi Do increases in physical activity encourage positive beliefs about further change in the ProActive cohort?
    Wendy Hardeman
    Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge CB2 0SR, UK
    Psychol Health 26:899-914. 2011
    ..Future studies could test the effect of such techniques on physical activity and a wider range of cognitive, affective and physiological consequences, using more frequent measurement intervals...
  68. ncbi Criterion-related validity of the last 7-day, short form of the International Physical Activity Questionnaire in Swedish adults
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK
    Public Health Nutr 9:258-65. 2006
    ..To examine the validity of the short, last 7-day, self-administered form of the International Physical Activity Questionnaire (IPAQ)...
  69. doi Physical activity and gain in abdominal adiposity and body weight: prospective cohort study in 288,498 men and women
    Ulf Ekelund
    Medical Research Council, Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 93:826-35. 2011
    ..The protective effect of physical activity (PA) on abdominal adiposity is unclear...
  70. ncbi Cardiorespiratory fitness, exercise capacity and physical activity in children: are we measuring the right thing?
    Ulf Ekelund
    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Hills Road, CB2 0QQ, Cambridge, UK
    Arch Dis Child 93:455-6. 2008
  71. pmc Perception versus reality awareness of physical activity levels of British children
    Kirsten Corder
    Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, United Kingdom
    Am J Prev Med 38:1-8. 2010
    ..Interventions to increase children's physical activity have had limited success. One reason may be that children and their parents overestimate children's levels of physical activity, although there is a small amount of data on this topic...
  72. doi Is it possible to assess free-living physical activity and energy expenditure in young people by self-report?
    Kirsten Corder
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 89:862-70. 2009
    ..It is unclear whether it is possible to accurately estimate physical activity energy expenditure (PAEE) by self-report in youth...
  73. ncbi Association between physical activity and blood pressure is modified by variants in the G-protein coupled receptor 10
    Paul W Franks
    University of Cambridge, Department of Public Health and Primary Care, Cambridge, UK
    Hypertension 43:224-8. 2004
    ..Knowledge of GPR10 genotype may define those who are least likely to benefit from physical activity. These findings may have relevance in the targeted treatment of hypertensive disease...
  74. ncbi Physical activity and mammographic breast density in the EPIC-Norfolk cohort study
    Tricia M Peters
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Epidemiol 167:579-85. 2008
    ..The lack of an association between physical activity and percentage breast density suggests that an association between physical activity and breast cancer risk is unlikely to be mediated through an effect on mammographic breast density...
  75. pmc Correlates of light and moderate-to-vigorous objectively measured physical activity in four-year-old children
    Esther M F van Sluijs
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom UKCRC Centre for Diet and Activity Research CEDAR, Cambridge, United Kingdom
    PLoS ONE 8:e74934. 2013
    ..The aim of the current study is to investigate associations between personal, social and environmental factors and objectively measured light and moderate-to-vigorous PA (LPA and MVPA, respectively) in four-year-old children...
  76. pmc Moderate to vigorous physical activity and sedentary time and cardiometabolic risk factors in children and adolescents
    Ulf Ekelund
    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrookes Hospital, PO Box 285, Cambridge, CB2 0QQ, Cambridge, United Kingdom
    JAMA 307:704-12. 2012
    ..Sparse data exist on the combined associations between physical activity and sedentary time with cardiometabolic risk factors in healthy children...
  77. pmc Objectively measured physical activity and fat mass in children: a bias-adjusted meta-analysis of prospective studies
    Desiree C Wilks
    Medical Research Council Collaborative Centre for Human Nutrition Research, Cambridge, United Kingdom
    PLoS ONE 6:e17205. 2011
    ....
  78. ncbi PGC-1alpha genotype modifies the association of volitional energy expenditure with [OV0312]O2max
    Paul W Franks
    Institute of Public Health, University of Cambridge, United Kingdom
    Med Sci Sports Exerc 35:1998-2004. 2003
    ..Other murine studies demonstrate that exercise increases PGC-1alpha mRNA expression...
  79. pmc Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children
    Adam Barker
    Medical Research Council Epidemiology Unit, Addenbrooke s Hospital, Institute of Metabolic Science, Cambridge, U K
    Diabetes 60:1805-12. 2011
    ..To investigate whether associations of common genetic variants recently identified for fasting glucose or insulin levels in nondiabetic adults are detectable in healthy children and adolescents...
  80. pmc Estimation of daily energy expenditure in pregnant and non-pregnant women using a wrist-worn tri-axial accelerometer
    Vincent T van Hees
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    PLoS ONE 6:e22922. 2011
    ....
  81. pmc Physical activity and dietary behaviour in a population-based sample of British 10-year old children: the SPEEDY study (Sport, Physical activity and Eating behaviour: environmental Determinants in Young people)
    Esther M F van Sluijs
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrookes Hospital, Hills Road, Cambridge, CB2 0QQ, UK
    BMC Public Health 8:388. 2008
    ..We present here the analyses of the PA, dietary and anthropometry data...
  82. pmc The contribution of prenatal environment and genetic factors to the association between birth weight and adult grip strength
    Charlotte L Ridgway
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    PLoS ONE 6:e17955. 2011
    ....
  83. doi Assessment of physical activity - a review of methodologies with reference to epidemiological research: a report of the exercise physiology section of the European Association of Cardiovascular Prevention and Rehabilitation
    Janet M Warren
    MRC Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, UK
    Eur J Cardiovasc Prev Rehabil 17:127-39. 2010
    ..A framework is presented to guide researchers on the selection of the most suitable tool for use in a specific study...
  84. ncbi Physical activity and obesity prevention: a review of the current evidence
    Nicholas J Wareham
    Medical Research Council Epidemiology Unit, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK
    Proc Nutr Soc 64:229-47. 2005
    ..Whilst efforts should continue to enhance the evidence base it is wise, in the meantime, to stick to the consensus public health advice of advocating 45-60 min moderate intensity activity daily to prevent obesity...
  85. ncbi Features of the metabolic syndrome are associated with objectively measured physical activity and fitness in Danish children: the European Youth Heart Study (EYHS)
    Søren Brage
    Institute of Sport and Health Biomechanics, University of Southern Denmark, Odense
    Diabetes Care 27:2141-8. 2004
    ..The purpose of this study was to examine the relationship between the metabolic syndrome and objectively measured physical activity and whether fitness modified this relationship...
  86. doi Efficacy of a theory-based behavioural intervention to increase physical activity in an at-risk group in primary care (ProActive UK): a randomised trial
    Ann Louise Kinmonth
    General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, University of Cambridge, UK
    Lancet 371:41-8. 2008
    ..Efforts to reverse this trend have not been successful. We aimed to assess the efficacy of a facilitated behavioural intervention to increase the physical activity of sedentary individuals at familial risk of diabetes...
  87. pmc Intensity and timing of physical activity in relation to postmenopausal breast cancer risk: the prospective NIH-AARP diet and health study
    Tricia M Peters
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, Bethesda, MD, USA
    BMC Cancer 9:349. 2009
    ..Despite strong evidence of an inverse association of physical activity with postmenopausal breast cancer risk, whether a certain intensity or time of life of physical activity is most effective for lowering breast cancer risk is not known...
  88. pmc Validation of the historical adulthood physical activity questionnaire (HAPAQ) against objective measurements of physical activity
    Herve Besson
    Medical Research Council Epidemiology Unit, IMS, Cambridge, UK
    Int J Behav Nutr Phys Act 7:54. 2010
    ..abstract:..
  89. ncbi Branched equation modeling of simultaneous accelerometry and heart rate monitoring improves estimate of directly measured physical activity energy expenditure
    Søren Brage
    Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense University, DK 5230 Odense, Denmark
    J Appl Physiol (1985) 96:343-51. 2004
    ..7%). In conclusion, combining HR and CSA by branched modeling improves estimates of PAEE. IC may be less crucial with this modeling technique...
  90. pmc Infant motor development predicts sports participation at age 14 years: northern Finland birth cohort of 1966
    Charlotte L Ridgway
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    PLoS ONE 4:e6837. 2009
    ..Motor proficiency is positively associated with physical activity levels. The aim of this study is to investigate associations between the timing of infant motor development and subsequent sports participation during adolescence...
  91. ncbi Energy expenditure assessed by heart rate and doubly labeled water in young athletes
    Ulf Ekelund
    Unit for Preventive Nutrition at Novum, Department of Medical Nutrition Biosciences, Karolinska Institutet, Stockholm, Sweden
    Med Sci Sports Exerc 34:1360-6. 2002
    ..We hypothesized that the accuracy of FLEX HR-estimated TEE would be affected by a) the definition of the FLEX HR and b) the type of training regimen...
  92. ncbi Temporal trends in physical activity in England: the Health Survey for England 1991 to 2004
    Emmanuel Stamatakis
    Department of Epidemiology and Public Health, 1 19 Torrington Place, WC1E 6BT, London, UK
    Prev Med 45:416-23. 2007
    ..Physical activity is an established risk factor for chronic disease but very little is known about its temporal trends in England. Such information is crucial for planning public health interventions...
  93. ncbi Leptin predicts a worsening of the features of the metabolic syndrome independently of obesity
    Paul W Franks
    Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Phoenix, AZ 85014, USA
    Obes Res 13:1476-84. 2005
    ..Our goal was to test the hypothesis that leptin predicts the development of the features of MS independently of obesity...
  94. ncbi Variation in the eNOS gene modifies the association between total energy expenditure and glucose intolerance
    Paul W Franks
    National Institute of DiabetesDigestiveKidney Diseases, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
    Diabetes 54:2795-801. 2005
    ..Gene-environment interactions such as this may help explain why replication of genetic association frequently fails...
  95. ncbi The European Youth Heart Survey (EYHS): an international study that addresses the multi-dimensional issues of CVD risk factors
    Eric Poortvliet
    Department of Bioscience, Karolinska Institutet, Huddinge, Sweden
    Forum Nutr 56:254-6. 2003
  96. ncbi PPARGC1A genotype (Gly482Ser) predicts exceptional endurance capacity in European men
    Alejandro Lucia
    European University of Madrid, Spain
    J Appl Physiol (1985) 99:344-8. 2005
    ..This finding has relevance from the perspective of physical performance, but it may also be informative for the targeted prevention of diseases associated with low fitness such as Type 2 diabetes...
  97. ncbi Physical activity in young children
    Ulf Ekelund
    Lancet 363:1163; author reply 1163-4. 2004
  98. ncbi Physical activity levels and patterns of 9- and 15-yr-old European children
    Chris J Riddoch
    Department of Exercise and Health Sciences, University of Bristol, Bristol, UK
    Med Sci Sports Exerc 36:86-92. 2004
    ..Very limited physical activity data exist that have been collected from representative samples of children and even fewer data collected where physical activity has been measured using objective methods...
  99. ncbi International physical activity questionnaire: 12-country reliability and validity
    Cora L Craig
    Canadian Fitness and Lifestyle Research Institute, Ottawa, Canada
    Med Sci Sports Exerc 35:1381-95. 2003
    ..The International Physical Activity Questionnaire (IPAQ) was developed as an instrument for cross-national monitoring of physical activity and inactivity...
  100. ncbi Effect of monitor placement and of activity setting on the MTI accelerometer output
    Agneta Yngve
    Unit for Preventive Nutrition, Department of Medical Nutrition, Karolinska Institutet, Stockholm, Sweden
    Med Sci Sports Exerc 35:320-6. 2003
    ..To examine the effect of monitor placement (hip vs back) and of activity setting (treadmill vs track) on the output from the Manufacturing Technology Inc. (MTI), activity monitor (model WAM 7164)...
  101. ncbi The validity of the Computer Science and Applications activity monitor for use in coronary artery disease patients during level walking
    Ulf Ekelund
    Unit of Preventive Nutrition, Department of Medical Nutrition Biosciences, Karolinska Institutet, Stockholm, Sweden
    Clin Physiol Funct Imaging 22:248-53. 2002
    ..In conclusion, the CSA activity monitor is a valid instrument for assessing the intensity of physical activity during treadmill walking in CAD patients. Energy expenditure can be predicted from body weight and activity counts...