U Ekelund

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Infancy and childhood growth and physical activity in adolescence: prospective birth cohort study from Brazil
    Pedro C Hallal
    Federal University of Pelotas, Rua Marechal Deodoro 1160, 96020 220, Pelotas, Brazil
    Int J Behav Nutr Phys Act 9:82. 2012
  2. pmc Randomised controlled trial of a complex intervention by primary care nurses to increase walking in patients aged 60-74 years: protocol of the PACE-Lift (Pedometer Accelerometer Consultation Evaluation - Lift) trial
    Tess Harris
    Population Health Research Centre, St George s University of London, UK
    BMC Public Health 13:5. 2013
  3. pmc Criterion validity of a 10-category scale for ranking physical activity in Norwegian women
    Kristin B Borch
    Department of Community Medicine, University of Tromsø, Norway
    Int J Behav Nutr Phys Act 9:2. 2012
  4. pmc Evaluation of the Indian Migration Study Physical Activity Questionnaire (IMS-PAQ): a cross-sectional study
    Ruth Sullivan
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    Int J Behav Nutr Phys Act 9:13. 2012
  5. pmc Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk
    Amy Luke
    Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA
    BMC Public Health 11:927. 2011
  6. pmc Moderate to vigorous physical activity and sedentary time and cardiometabolic risk factors in children and adolescents
    Ulf Ekelund
    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrookes Hospital, PO Box 285, Cambridge, CB2 0QQ, Cambridge, United Kingdom
    JAMA 307:704-12. 2012
  7. pmc An investigation of patterns of children's sedentary and vigorous physical activity throughout the week
    Rebekah M Steele
    Medical Research Council Epidemiology Unit, Cambridge, UK
    Int J Behav Nutr Phys Act 7:88. 2010
  8. pmc Validation of the historical adulthood physical activity questionnaire (HAPAQ) against objective measurements of physical activity
    Herve Besson
    Medical Research Council Epidemiology Unit, IMS, Cambridge, UK
    Int J Behav Nutr Phys Act 7:54. 2010
  9. pmc International children's accelerometry database (ICAD): design and methods
    Lauren B Sherar
    College of Kinesiology, University of Saskatchewan, Saskatoon, SK, Canada
    BMC Public Health 11:485. 2011
  10. pmc Physical activity and dietary behaviour in a population-based sample of British 10-year old children: the SPEEDY study (Sport, Physical activity and Eating behaviour: environmental Determinants in Young people)
    Esther M F van Sluijs
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrookes Hospital, Hills Road, Cambridge, CB2 0QQ, UK
    BMC Public Health 8:388. 2008

Detail Information

Publications115 found, 100 shown here

  1. pmc Infancy and childhood growth and physical activity in adolescence: prospective birth cohort study from Brazil
    Pedro C Hallal
    Federal University of Pelotas, Rua Marechal Deodoro 1160, 96020 220, Pelotas, Brazil
    Int J Behav Nutr Phys Act 9:82. 2012
    ..The aim of the present study was to evaluate the effects of prenatal, infancy and childhood weight and length/height gains on objectively-measured physical activity (PA) in adolescence...
  2. pmc Randomised controlled trial of a complex intervention by primary care nurses to increase walking in patients aged 60-74 years: protocol of the PACE-Lift (Pedometer Accelerometer Consultation Evaluation - Lift) trial
    Tess Harris
    Population Health Research Centre, St George s University of London, UK
    BMC Public Health 13:5. 2013
    ..This protocol describes an innovative intervention to increase walking in older people, incorporating pedometer and accelerometer feedback within a primary care nurse physical activity consultation, using behaviour change techniques...
  3. pmc Criterion validity of a 10-category scale for ranking physical activity in Norwegian women
    Kristin B Borch
    Department of Community Medicine, University of Tromsø, Norway
    Int J Behav Nutr Phys Act 9:2. 2012
    ..We compared the self-administered PA questionnaire from the Norwegian Women and Cancer Study (NOWAC) with a criterion method in middle-aged Norwegian women...
  4. pmc Evaluation of the Indian Migration Study Physical Activity Questionnaire (IMS-PAQ): a cross-sectional study
    Ruth Sullivan
    Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
    Int J Behav Nutr Phys Act 9:13. 2012
    ..We examined the reliability and validity of the Indian Migration Study Physical Activity Questionnaire (IMS-PAQ) in urban and rural groups in India...
  5. pmc Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk
    Amy Luke
    Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA
    BMC Public Health 11:927. 2011
    ..However there are few empirical data to support the assertion that low levels of energy expenditure in activity is a causal factor in the current obesity epidemic are very limited...
  6. pmc Moderate to vigorous physical activity and sedentary time and cardiometabolic risk factors in children and adolescents
    Ulf Ekelund
    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrookes Hospital, PO Box 285, Cambridge, CB2 0QQ, Cambridge, United Kingdom
    JAMA 307:704-12. 2012
    ..Sparse data exist on the combined associations between physical activity and sedentary time with cardiometabolic risk factors in healthy children...
  7. pmc An investigation of patterns of children's sedentary and vigorous physical activity throughout the week
    Rebekah M Steele
    Medical Research Council Epidemiology Unit, Cambridge, UK
    Int J Behav Nutr Phys Act 7:88. 2010
    ..abstract:..
  8. pmc Validation of the historical adulthood physical activity questionnaire (HAPAQ) against objective measurements of physical activity
    Herve Besson
    Medical Research Council Epidemiology Unit, IMS, Cambridge, UK
    Int J Behav Nutr Phys Act 7:54. 2010
    ..abstract:..
  9. pmc International children's accelerometry database (ICAD): design and methods
    Lauren B Sherar
    College of Kinesiology, University of Saskatchewan, Saskatoon, SK, Canada
    BMC Public Health 11:485. 2011
    ..This manuscript describes the contributing studies, outlines the standardized methods used to process the accelerometer data and provides the initial questions which will be addressed using this novel data repository...
  10. pmc Physical activity and dietary behaviour in a population-based sample of British 10-year old children: the SPEEDY study (Sport, Physical activity and Eating behaviour: environmental Determinants in Young people)
    Esther M F van Sluijs
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrookes Hospital, Hills Road, Cambridge, CB2 0QQ, UK
    BMC Public Health 8:388. 2008
    ..We present here the analyses of the PA, dietary and anthropometry data...
  11. pmc Intensity and timing of physical activity in relation to postmenopausal breast cancer risk: the prospective NIH-AARP diet and health study
    Tricia M Peters
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, Bethesda, MD, USA
    BMC Cancer 9:349. 2009
    ..Despite strong evidence of an inverse association of physical activity with postmenopausal breast cancer risk, whether a certain intensity or time of life of physical activity is most effective for lowering breast cancer risk is not known...
  12. pmc Objectively measured moderate- and vigorous-intensity physical activity but not sedentary time predicts insulin resistance in high-risk individuals
    Ulf Ekelund
    Medical Research Council, Epidemiology Unit, Cambridge, UK
    Diabetes Care 32:1081-6. 2009
    ....
  13. ncbi request reprint The criterion validity of a last 7-day physical activity questionnaire (SAPAQ) for use in adolescents with a wide variation in body fat: the Stockholm Weight Development Study
    U Ekelund
    Medical Research Council Epidemiology Unit, Elsie Widdowson Laboratory, Cambridge, UK
    Int J Obes (Lond) 30:1019-21. 2006
    ..The aim of the present study was to assess the criterion validity of a newly developed self-reported last 7-day physical activity questionnaire (SAPAQ) for use in Swedish adolescents with a wide variation in body fatness...
  14. ncbi request reprint Does physical activity equally predict gain in fat mass among obese and nonobese young adults?
    U Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, UK
    Int J Obes (Lond) 31:65-71. 2007
    ..Differences in energy metabolism and physical activity (PA) may contribute to the long-term regulation of body weight (BW)...
  15. ncbi request reprint Criterion-related validity of the last 7-day, short form of the International Physical Activity Questionnaire in Swedish adults
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK
    Public Health Nutr 9:258-65. 2006
    ..To examine the validity of the short, last 7-day, self-administered form of the International Physical Activity Questionnaire (IPAQ)...
  16. pmc TV viewing and physical activity are independently associated with metabolic risk in children: the European Youth Heart Study
    Ulf Ekelund
    Epidemiology Unit, Medical Research Council, Cambridge, United Kingdom
    PLoS Med 3:e488. 2006
    ..TV viewing has been linked to metabolic-risk factors in youth. However, it is unclear whether this association is independent of physical activity (PA) and obesity...
  17. doi request reprint What proportion of youth are physically active? Measurement issues, levels and recent time trends
    Ulf Ekelund
    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrookes Hospital, Box 285, Cambridge CB2 0QQ, UK
    Br J Sports Med 45:859-65. 2011
    ..Current levels and temporal trends in PA and sport participation and the effect of assessment method on data interpretation will be summarised...
  18. ncbi request reprint Physical activity and metabolic risk in individuals with a family history of type 2 diabetes
    Ulf Ekelund
    MRC Epidemiology Unit, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, U K
    Diabetes Care 30:337-42. 2007
    ....
  19. ncbi request reprint Time spent being sedentary and weight gain in healthy adults: reverse or bidirectional causality?
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 88:612-7. 2008
    ..Whether obesity is a cause or a consequence of a sedentary lifestyle has not yet been fully elucidated, which leaves uncertainty about the direction of causality...
  20. ncbi request reprint Independent associations of physical activity and cardiorespiratory fitness with metabolic risk factors in children: the European youth heart study
    U Ekelund
    MRC Epidemiology Unit, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge, CB1 9NL, UK
    Diabetologia 50:1832-40. 2007
    ....
  21. doi request reprint Physical activity and gain in abdominal adiposity and body weight: prospective cohort study in 288,498 men and women
    Ulf Ekelund
    Medical Research Council, Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 93:826-35. 2011
    ..The protective effect of physical activity (PA) on abdominal adiposity is unclear...
  22. ncbi request reprint Cardiorespiratory fitness, exercise capacity and physical activity in children: are we measuring the right thing?
    Ulf Ekelund
    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Hills Road, CB2 0QQ, Cambridge, UK
    Arch Dis Child 93:455-6. 2008
  23. ncbi request reprint Increase in physical activity energy expenditure is associated with reduced metabolic risk independent of change in fatness and fitness
    Ulf Ekelund
    MRC Epidemiology Unit, Elsie Widdowson Laboratory, Fulbourne Road, CB1 9NL, Cambridge, U K
    Diabetes Care 30:2101-6. 2007
    ..We sought to examine whether change in physical activity energy expenditure (PAEE) is associated with change in metabolic risk factors and whether this association is independent of change in fat mass and aerobic fitness...
  24. pmc Increasing overall physical activity and aerobic fitness is associated with improvements in metabolic risk: cohort analysis of the ProActive trial
    R K Simmons
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, P O Box 285, Hills Road, Cambridge, CB2 0QQ, UK
    Diabetologia 51:787-94. 2008
    ....
  25. ncbi request reprint Physical activity energy expenditure may mediate the relationship between plasma leptin levels and worsening insulin resistance independently of adiposity
    P W Franks
    Medical Research Council Epidemiology Unit, Cambridge, UK
    J Appl Physiol 102:1921-6. 2007
    ..Hyperleptinemia predicts a relative decline in PAEE and worsening insulin resistance, possibly via shared molecular pathways...
  26. ncbi request reprint Does the association of habitual physical activity with the metabolic syndrome differ by level of cardiorespiratory fitness?
    Paul W Franks
    MRC Epidemiology Unit, Cambridge, UK
    Diabetes Care 27:1187-93. 2004
    ..The purpose of this study was, therefore, to describe the association between physical activity and the metabolic syndrome and to test whether fitness level modifies this relationship...
  27. pmc The association of intensity and overall level of physical activity energy expenditure with a marker of insulin resistance
    F K Assah
    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Box 285, Hills Road, Cambridge, CB2 0QQ, UK
    Diabetologia 51:1399-407. 2008
    ..We examined the association of overall level and intensity of physical activity with fasting insulin level, a marker of insulin resistance...
  28. pmc Fat-free mass mediates the association between birth weight and aerobic fitness in youth
    C L Ridgway
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Int J Pediatr Obes 6:e590-6. 2011
    ..To investigate whether birth weight acts as a biological determinant of later aerobic fitness, and whether fat-free mass may mediate this association...
  29. pmc Objectively measured sedentary time may predict insulin resistance independent of moderate- and vigorous-intensity physical activity
    Hendrik J F Helmerhorst
    Medical Research Council Epidemiology Unit, Cambridge, UK
    Diabetes 58:1776-9. 2009
    ....
  30. doi request reprint The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial
    F M Finucane
    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Box 285, Hills Road, Cambridge CB2 0QQ, UK
    Diabetologia 53:624-31. 2010
    ..We sought to determine the effect of an aerobic exercise intervention on clustered metabolic risk and related outcomes in healthy older adults in a single-centre, explanatory randomised controlled trial...
  31. doi request reprint Targeting sedentary time or moderate- and vigorous-intensity activity: independent relations with adiposity in a population-based sample of 10-y-old British children
    Rebekah M Steele
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Am J Clin Nutr 90:1185-92. 2009
    ..It is unclear whether subcomponents of physical activity (PA) are associated with adiposity independent of time spent while sedentary...
  32. doi request reprint Obesity is associated with altered lung function independently of physical activity and fitness
    Rebekah M Steele
    Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Obesity (Silver Spring) 17:578-84. 2009
    ..These associations were independent of the degree of physical activity and aerobic fitness in this cohort...
  33. pmc Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study
    Clara Kelliny
    Medical Research Council Epidemiology Unit, Addenbrooke s Hospital, Institute of Metabolic Science, Cambridge, U K
    Diabetes 58:2939-45. 2009
    ..The goal of this study was to investigate whether the effects of common genetic variants associated with fasting glucose in adults are detectable in healthy children...
  34. ncbi request reprint Physical activity and mammographic breast density in the EPIC-Norfolk cohort study
    Tricia M Peters
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Epidemiol 167:579-85. 2008
    ..The lack of an association between physical activity and percentage breast density suggests that an association between physical activity and breast cancer risk is unlikely to be mediated through an effect on mammographic breast density...
  35. ncbi request reprint Comparison of PAEE from combined and separate heart rate and movement models in children
    Kirsten Corder
    Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom
    Med Sci Sports Exerc 37:1761-7. 2005
    ....
  36. ncbi request reprint Reliability and validity of the combined heart rate and movement sensor Actiheart
    S Brage
    MRC Epidemiology Unit, Institute of Public Health, University of Cambridge, CB1 9NL, UK
    Eur J Clin Nutr 59:561-70. 2005
    ..The Actiheart, a combined heart rate (HR) and movement sensor, is designed to assess physical activity in populations...
  37. doi request reprint Altered respiratory function is associated with increased metabolic risk, independently of adiposity, fitness and physical activity
    R M Steele
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Diabet Med 26:362-9. 2009
    ....
  38. doi request reprint Objectively measured physical activity and obesity prevention in children, adolescents and adults: a systematic review of prospective studies
    D C Wilks
    Medical Research Council Human Nutrition Research, Medical Research Council Epidemiology Unit, Cambridge, UK
    Obes Rev 12:e119-29. 2011
    ..Intervention studies show generally no effect on either PA or adiposity. In conclusion, despite the well-established health benefits of PA, it may not be a key determinant of excessive gain in adiposity...
  39. doi request reprint A cross-sectional analysis of physical activity and obesity indicators in European participants of the EPIC-PANACEA study
    H Besson
    Medical Research Council, Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Int J Obes (Lond) 33:497-506. 2009
    ....
  40. pmc Predicting physical activity energy expenditure using accelerometry in adults from sub-Sahara Africa
    Felix K Assah
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Obesity (Silver Spring) 17:1588-95. 2009
    ..Accelerometry could be used to predict PAEE in this population and, therefore, has important applications for monitoring population levels of total physical activity patterns...
  41. ncbi request reprint Accelerometers and pedometers: methodology and clinical application
    Kirsten Corder
    Medical Research Council Epidemiology Unit, Cambridge, UK
    Curr Opin Clin Nutr Metab Care 10:597-603. 2007
    ..Recommendations are given for the use of movement sensors during free-living conditions and methods of data analysis and interpretation are discussed...
  42. doi request reprint Birth size, infant weight gain, and motor development influence adult physical performance
    Charlotte L Ridgway
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Med Sci Sports Exerc 41:1212-21. 2009
    ....
  43. doi request reprint Absence of association between the INSIG2 gene polymorphism (rs7566605) and obesity in the European Youth Heart Study (EYHS)
    Karani S Vimaleswaran
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Obesity (Silver Spring) 17:1453-7. 2009
    ..There was also no evidence of interaction between genotype and physical activity (P = 0.95). Despite an adequately powered study, our findings suggest that rs7566605 is not associated with obesity-related traits and lipids in the EYHS...
  44. doi request reprint Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study
    C Langenberg
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Box 285, Cambridge CB2 0QQ, UK E mail
    Diabetologia 54:2272-82. 2011
    ..This case-cohort study aims to investigate how genetic and potentially modifiable lifestyle and behavioural factors, particularly diet and physical activity, interact in their influence on the risk of developing type 2 diabetes...
  45. doi request reprint Physical activity attenuates the body mass index-increasing influence of genetic variation in the FTO gene
    Karani S Vimaleswaran
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge CB2 0QQ, United Kingdom
    Am J Clin Nutr 90:425-8. 2009
    ..Intronic variation in the FTO (fat mass and obesity-associated) gene has been unequivocally associated with increased body mass index (BMI; in kg/m(2)) and the risk of obesity in populations of different ethnicity...
  46. doi request reprint Assessment of physical activity in youth
    Kirsten Corder
    Institute of Metabolic Science, Addenbrooke s Hospital CB2 0QQ Cambridge, UK
    J Appl Physiol 105:977-87. 2008
    ..Although multisensor systems may be more accurate, this must be balanced against feasibility, a balance that shifts with technological and scientific advances and should be considered at the beginning of every new study...
  47. pmc Breakfast consumption and physical activity in British adolescents
    K Corder
    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Box 285, Hills Road, Cambridge CB2 0QQ, UK
    Br J Nutr 105:316-21. 2011
    ....
  48. ncbi request reprint Objectively measured physical activity correlates with indices of insulin resistance in Danish children. The European Youth Heart Study (EYHS)
    S Brage
    Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Main Campus, Odense University, Odense, Denmark
    Int J Obes Relat Metab Disord 28:1503-8. 2004
    ..To explore the association between measures of insulin resistance with objectively assessed physical activity...
  49. pmc Physical activity, cardiorespiratory fitness, and the metabolic syndrome in youth
    Rebekah M Steele
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke s Hospital, Hills Rd, Cambridge CB2 0QQ, UK
    J Appl Physiol 105:342-51. 2008
    ..Public health approaches that encourage increased physical activity and reduce sedentary behaviors may prove useful in reducing the population burden associated with metabolic risk...
  50. pmc Randomized controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial
    Francis M Finucane
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    BMC Endocr Disord 9:15. 2009
    ..TRIAL REGISTRATION: Current Controlled Trials: ISRCTN60986572...
  51. pmc Genetic variation in LIN28B is associated with the timing of puberty
    Ken K Ong
    Medical Research Council MRC Epidemiology Unit, Addenbrooke s Hospital, Cambridge, UK
    Nat Genet 41:729-33. 2009
    ..These studies identify variation in LIN28B, a potent and specific regulator of microRNA processing, as the first genetic determinant regulating the timing of human pubertal growth and development...
  52. pmc Perception versus reality awareness of physical activity levels of British children
    Kirsten Corder
    Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, United Kingdom
    Am J Prev Med 38:1-8. 2010
    ..Interventions to increase children's physical activity have had limited success. One reason may be that children and their parents overestimate children's levels of physical activity, although there is a small amount of data on this topic...
  53. doi request reprint Physical activity energy expenditure of adolescents in India
    Kirsten Corder
    MRC Epidemiology Unit, Institute of Metabolic Science, Box 285 Addenbrooke s Hospital, Cambridge, UK
    Obesity (Silver Spring) 18:2212-9. 2010
    ..Further research is necessary to investigate the association between PA and health outcomes in Indian adolescents...
  54. doi request reprint Association between birth weight and visceral fat in adults
    Emanuella De Lucia Rolfe
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 92:347-52. 2010
    ..Several studies reported inverse associations between birth weight and central adiposity in adults. However, few studies investigated the contributions of different abdominal fat compartments...
  55. doi request reprint Changes in children's physical activity over 12 months: longitudinal results from the SPEEDY study
    Kirsten Corder
    MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke s Hospital, Hills Road, Cambridge, CB2 0QQ, United Kingdom
    Pediatrics 126:e926-35. 2010
    ..We measured physical activity changes among 10-year-old British children over 12 months and assessed biological and demographic determinants...
  56. doi request reprint Relationship between subdomains of total physical activity and mortality
    Herve Besson
    Epidemiology Unit, Medical Research Council, Cambridge, United Kingdom
    Med Sci Sports Exerc 40:1909-15. 2008
    ..However, it is unclear how this association varies according to the domain of life in which the activity takes place...
  57. doi request reprint Prevalence and correlates of the metabolic syndrome in a population-based sample of European youth
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, UK
    Am J Clin Nutr 89:90-6. 2009
    ..Until recently, there has been no unified definition of the metabolic syndrome (MetS) in the youth. Therefore, the prevalence of MetS and its association with potential correlates are largely unknown...
  58. doi request reprint Estimating physical activity energy expenditure, sedentary time, and physical activity intensity by self-report in adults
    Herve Besson
    Medical Research Council, Epidemiology Unit, Cambridge, UK
    Am J Clin Nutr 91:106-14. 2010
    ..Few questionnaires that assess usual physical activity have been reported to be valid for all different subdimensions of physical activity...
  59. pmc Habitual energy expenditure modifies the association between NOS3 gene polymorphisms and blood pressure
    Karani S Vimaleswaran
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Am J Hypertens 21:297-302. 2008
    ..Thus, energy expenditure may modify the association between the genetic variation at NOS3 and blood pressure...
  60. doi request reprint Efficacy of a theory-based behavioural intervention to increase physical activity in an at-risk group in primary care (ProActive UK): a randomised trial
    Ann Louise Kinmonth
    General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, University of Cambridge, UK
    Lancet 371:41-8. 2008
    ..Efforts to reverse this trend have not been successful. We aimed to assess the efficacy of a facilitated behavioural intervention to increase the physical activity of sedentary individuals at familial risk of diabetes...
  61. ncbi request reprint Association between physical activity and blood pressure is modified by variants in the G-protein coupled receptor 10
    Paul W Franks
    University of Cambridge, Department of Public Health and Primary Care, Cambridge, UK
    Hypertension 43:224-8. 2004
    ..Knowledge of GPR10 genotype may define those who are least likely to benefit from physical activity. These findings may have relevance in the targeted treatment of hypertensive disease...
  62. ncbi request reprint Upward weight percentile crossing in infancy and early childhood independently predicts fat mass in young adults: the Stockholm Weight Development Study (SWEDES)
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Am J Clin Nutr 83:324-30. 2006
    ..Rapid early postnatal weight gain predicts increased subsequent obesity and related disease risks. However, the exact timing of adverse rapid postnatal weight gain is unclear...
  63. ncbi request reprint Effect of combined movement and heart rate monitor placement on physical activity estimates during treadmill locomotion and free-living
    Søren Brage
    MRC Epidemiology Unit, Institute of Public Health, University of Cambridge, Elsie Widdowson Laboratory, Fulbourn Road, CB1 9NL, Cambridge, United Kingdom
    Eur J Appl Physiol 96:517-24. 2006
    ..Regardless of which position is used, this has little or no effect on movement counts and energy expenditure estimates, which is encouraging for studies where research participants may have to position the monitors themselves...
  64. ncbi request reprint Body movement and physical activity energy expenditure in children and adolescents: how to adjust for differences in body size and age
    Ulf Ekelund
    MRC Epidemiology Unit, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, United Kingdom
    Am J Clin Nutr 79:851-6. 2004
    ..Physical activity data in children and adolescents who differ in body size and age are influenced by whether physical activity is expressed in terms of body movement or energy expenditure...
  65. ncbi request reprint Physical activity and obesity prevention: a review of the current evidence
    Nicholas J Wareham
    Medical Research Council Epidemiology Unit, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK
    Proc Nutr Soc 64:229-47. 2005
    ..Whilst efforts should continue to enhance the evidence base it is wise, in the meantime, to stick to the consensus public health advice of advocating 45-60 min moderate intensity activity daily to prevent obesity...
  66. ncbi request reprint Physical activity energy expenditure predicts changes in body composition in middle-aged healthy whites: effect modification by age
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Am J Clin Nutr 81:964-9. 2005
    ..It is unclear whether physical activity energy expenditure (PAEE) predicts changes in body composition...
  67. ncbi request reprint Physical activity energy expenditure predicts progression toward the metabolic syndrome independently of aerobic fitness in middle-aged healthy Caucasians: the Medical Research Council Ely Study
    Ulf Ekelund
    Epidemiology Unit, Medical Research Council, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, U K
    Diabetes Care 28:1195-200. 2005
    ....
  68. ncbi request reprint Oxygen uptakes adjusted for body composition in normal-weight and obese adolescents
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Obes Res 12:513-20. 2004
    ....
  69. ncbi request reprint Associations between physical activity and fat mass in adolescents: the Stockholm Weight Development Study
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Am J Clin Nutr 81:355-60. 2005
    ..Obesity is multifactorial. However, the accumulation of fat mass (FM) is proposed to be due to a positive energy balance, which may be caused by reduced physical activity (PA)...
  70. pmc The ProActive trial protocol - a randomised controlled trial of the efficacy of a family-based, domiciliary intervention programme to increase physical activity among individuals at high risk of diabetes [ISRCTN61323766]
    Kate Williams
    General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, Institute of Public Health, Forvie Site, Robinson Way, Cambridge CB2 2SR, UK
    BMC Public Health 4:48. 2004
    ..While previous evaluations of interventions to increase physical activity have involved communities or individuals with established disease, less attention has been given to interventions for individuals at risk of disease...
  71. ncbi request reprint Features of the metabolic syndrome are associated with objectively measured physical activity and fitness in Danish children: the European Youth Heart Study (EYHS)
    Søren Brage
    Institute of Sport and Health Biomechanics, University of Southern Denmark, Odense
    Diabetes Care 27:2141-8. 2004
    ..The purpose of this study was to examine the relationship between the metabolic syndrome and objectively measured physical activity and whether fitness modified this relationship...
  72. ncbi request reprint Associations between objectively assessed physical activity and indicators of body fatness in 9- to 10-y-old European children: a population-based study from 4 distinct regions in Europe (the European Youth Heart Study)
    Ulf Ekelund
    MRC Epidemiology Unit, Strangeways Research Laboratories, Wort s Causeway, Cambridge CB1 8RN, United Kingdom
    Am J Clin Nutr 80:584-90. 2004
    ..The rising prevalence of obesity in children may be due to a reduction in physical activity (PA)...
  73. ncbi request reprint Branched equation modeling of simultaneous accelerometry and heart rate monitoring improves estimate of directly measured physical activity energy expenditure
    Søren Brage
    Institute of Sport Science and Clinical Biomechanics, University of Southern Denmark, Odense University, DK 5230 Odense, Denmark
    J Appl Physiol 96:343-51. 2004
    ..7%). In conclusion, combining HR and CSA by branched modeling improves estimates of PAEE. IC may be less crucial with this modeling technique...
  74. ncbi request reprint Hierarchy of individual calibration levels for heart rate and accelerometry to measure physical activity
    Søren Brage
    MRC Epidemiology Unit, Cambridge CB1 9NL, UK
    J Appl Physiol 103:682-92. 2007
    ..In conclusion, a substantial proportion of the between-individual variance in relationships between PAI, accelerometry, and HR is captured with simple calibration procedures, feasible for use in epidemiological studies...
  75. ncbi request reprint Is the ArteACC index a valid indicator of free-living physical activity in adolescents?
    Ulf Ekelund
    Diabetes Research Group, Institute of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
    Obes Res 11:793-801. 2003
    ..A secondary aim was to develop regression equations for prediction of total energy expenditure (TEE) and activity energy expenditure [AEE = 0.9 x TEE - resting metabolic rate (RMR)]...
  76. ncbi request reprint Comparison of two methods to assess PAEE during six activities in children
    Kirsten Corder
    1MRC Epidemiology Unit, Cambridge, United Kingdom
    Med Sci Sports Exerc 39:2180-8. 2007
    ..Three PAEE-prediction models derived using the current data, and five previously published prediction models were cross-validated to estimate PAEE in this sample...
  77. ncbi request reprint Association of weight gain in infancy and early childhood with metabolic risk in young adults
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Cambridge CB1 9NL, United Kingdom
    J Clin Endocrinol Metab 92:98-103. 2007
    ..Early postnatal life has been suggested as an important window during which risks for long-term health may be influenced...
  78. ncbi request reprint Comparison of two Actigraph models for assessing free-living physical activity in Indian adolescents
    Kirsten Corder
    MRC Epidemiology Unit, Institute of Metabolic Science, Box 285 Addenbrooke s Hospital, Cambridge CB2 0QQ, UK
    J Sports Sci 25:1607-11. 2007
    ....
  79. pmc The contribution of prenatal environment and genetic factors to the association between birth weight and adult grip strength
    Charlotte L Ridgway
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    PLoS ONE 6:e17955. 2011
    ....
  80. pmc Free-living physical activity energy expenditure is strongly related to glucose intolerance in Cameroonian adults independently of obesity
    Felix K Assah
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Diabetes Care 32:367-9. 2009
    ..We examined the cross-sectional association between objectively measured free-living physical activity energy expenditure (PAEE) and glucose tolerance in adult Cameroonians without known diabetes...
  81. doi request reprint Assessment of physical activity - a review of methodologies with reference to epidemiological research: a report of the exercise physiology section of the European Association of Cardiovascular Prevention and Rehabilitation
    Janet M Warren
    MRC Human Nutrition Research, Elsie Widdowson Laboratory, Cambridge, UK
    Eur J Cardiovasc Prev Rehabil 17:127-39. 2010
    ..A framework is presented to guide researchers on the selection of the most suitable tool for use in a specific study...
  82. pmc Rate of weight gain predicts change in physical activity levels: a longitudinal analysis of the EPIC-Norfolk cohort
    R Golubic
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Int J Obes (Lond) 37:404-9. 2013
    ..To investigate the relationship of body weight and its changes over time with physical activity (PA)...
  83. pmc Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies
    Marcel den Hoed
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Diabetes 59:2980-8. 2010
    ..We examined associations of variants in these loci with anthropometric traits in children and adolescents...
  84. pmc Infant motor development predicts sports participation at age 14 years: northern Finland birth cohort of 1966
    Charlotte L Ridgway
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    PLoS ONE 4:e6837. 2009
    ..Motor proficiency is positively associated with physical activity levels. The aim of this study is to investigate associations between the timing of infant motor development and subsequent sports participation during adolescence...
  85. doi request reprint Is it possible to assess free-living physical activity and energy expenditure in young people by self-report?
    Kirsten Corder
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 89:862-70. 2009
    ..It is unclear whether it is possible to accurately estimate physical activity energy expenditure (PAEE) by self-report in youth...
  86. pmc Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples
    M den Hoed
    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Int J Obes (Lond) 37:191-6. 2013
    ..Meta-analysis of case-control genome-wide association studies (GWAS) for early onset and morbid obesity identified four variants in/near the PRL, PTER, MAF and NPC1 genes...
  87. pmc Do physical activity and aerobic fitness moderate the association between birth weight and metabolic risk in youth?: the European Youth Heart Study
    Charlotte L Ridgway
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Diabetes Care 34:187-92. 2011
    ..Lower birth weight has been associated with a greater risk of metabolic diseases. The aim of this study was examine whether physical activity and aerobic fitness may modify associations between birth weigh and metabolic risk...
  88. pmc Urbanization, physical activity, and metabolic health in sub-Saharan Africa
    Felix K Assah
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Diabetes Care 34:491-6. 2011
    ..We examined the independent associations between objectively measured free-living physical activity energy expenditure (PAEE) and the metabolic syndrome in adults in rural and urban Cameroon...
  89. ncbi request reprint Physical activity in young children
    Ulf Ekelund
    Lancet 363:1163; author reply 1163-4. 2004
  90. ncbi request reprint Physical activity but not energy expenditure is reduced in obese adolescents: a case-control study
    Ulf Ekelund
    Unit for Preventive Nutrition, Department of Medical Nutrition Biosciences, Karolinska Institutet, Stockholm, Sweden
    Am J Clin Nutr 76:935-41. 2002
    ..The influence of physical activity on body weight in children and adolescents is controversial...
  91. ncbi request reprint The validity of the Computer Science and Applications activity monitor for use in coronary artery disease patients during level walking
    Ulf Ekelund
    Unit of Preventive Nutrition, Department of Medical Nutrition Biosciences, Karolinska Institutet, Stockholm, Sweden
    Clin Physiol Funct Imaging 22:248-53. 2002
    ..In conclusion, the CSA activity monitor is a valid instrument for assessing the intensity of physical activity during treadmill walking in CAD patients. Energy expenditure can be predicted from body weight and activity counts...
  92. ncbi request reprint PGC-1alpha genotype modifies the association of volitional energy expenditure with [OV0312]O2max
    Paul W Franks
    Institute of Public Health, University of Cambridge, United Kingdom
    Med Sci Sports Exerc 35:1998-2004. 2003
    ..Other murine studies demonstrate that exercise increases PGC-1alpha mRNA expression...
  93. ncbi request reprint Effect of monitor placement and of activity setting on the MTI accelerometer output
    Agneta Yngve
    Unit for Preventive Nutrition, Department of Medical Nutrition, Karolinska Institutet, Stockholm, Sweden
    Med Sci Sports Exerc 35:320-6. 2003
    ..To examine the effect of monitor placement (hip vs back) and of activity setting (treadmill vs track) on the output from the Manufacturing Technology Inc. (MTI), activity monitor (model WAM 7164)...
  94. ncbi request reprint Energy expenditure assessed by heart rate and doubly labeled water in young athletes
    Ulf Ekelund
    Unit for Preventive Nutrition at Novum, Department of Medical Nutrition Biosciences, Karolinska Institutet, Stockholm, Sweden
    Med Sci Sports Exerc 34:1360-6. 2002
    ..We hypothesized that the accuracy of FLEX HR-estimated TEE would be affected by a) the definition of the FLEX HR and b) the type of training regimen...
  95. ncbi request reprint Physical activity levels and patterns of 9- and 15-yr-old European children
    Chris J Riddoch
    Department of Exercise and Health Sciences, University of Bristol, Bristol, UK
    Med Sci Sports Exerc 36:86-92. 2004
    ..Very limited physical activity data exist that have been collected from representative samples of children and even fewer data collected where physical activity has been measured using objective methods...
  96. ncbi request reprint International physical activity questionnaire: 12-country reliability and validity
    Cora L Craig
    Canadian Fitness and Lifestyle Research Institute, Ottawa, Canada
    Med Sci Sports Exerc 35:1381-95. 2003
    ..The International Physical Activity Questionnaire (IPAQ) was developed as an instrument for cross-national monitoring of physical activity and inactivity...
  97. ncbi request reprint Variation in the eNOS gene modifies the association between total energy expenditure and glucose intolerance
    Paul W Franks
    National Institute of DiabetesDigestiveKidney Diseases, 1550 E Indian School Rd, Phoenix, AZ 85014, USA
    Diabetes 54:2795-801. 2005
    ..Gene-environment interactions such as this may help explain why replication of genetic association frequently fails...
  98. ncbi request reprint Physical activity and sedentary behaviors among Finnish youth
    Tuija Tammelin
    Finnish Institute of Occupational Health, Oulu, Finland
    Med Sci Sports Exerc 39:1067-74. 2007
    ..d(-1)) and to examine associations between physical activity and different sedentary behaviors...
  99. doi request reprint Objectively measured physical activity and bone strength in 9-year-old boys and girls
    Luis B Sardinha
    Exercise and Health Laboratory, Faculty of Human Movement, Technical University of Lisbon Estrada da Costa, 1495 688 Cruz Quebrada, Portugal
    Pediatrics 122:e728-36. 2008
    ..The purpose of this work was to analyze the relationship between intensity and duration of physical activity and composite indices of femoral neck strength and bone-mineral content of the femoral neck, lumbar spine, and total body...
  100. ncbi request reprint Temporal trends in physical activity in England: the Health Survey for England 1991 to 2004
    Emmanuel Stamatakis
    Department of Epidemiology and Public Health, 1 19 Torrington Place, WC1E 6BT, London, UK
    Prev Med 45:416-23. 2007
    ..Physical activity is an established risk factor for chronic disease but very little is known about its temporal trends in England. Such information is crucial for planning public health interventions...
  101. ncbi request reprint Physical activity and clustered cardiovascular risk in children: a cross-sectional study (The European Youth Heart Study)
    Lars Bo Andersen
    Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway
    Lancet 368:299-304. 2006
    ..This study's aim was to assess the associations of objectively measured physical activity with clustering of cardiovascular disease risk factors in children and derive guidelines on the basis of this analysis...