Research Topics
Genomes and GenesSpecies | S EbrahimSummaryAffiliation: University of Bristol Country: UK Publications
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Publications
Improving stroke patients' care: a patient held record is not enoughM Ayana
Department of Primary Care and Population Sciences, Royal Free Hospital School of Medicine, Rowland Hill Street, London NW3 2PF
BMC Health Serv Res 1:1. 2001..The purpose of this study was to evaluate whether a patient-held record (PHR) would result in greater patient satisfaction and better care planning for stroke patients...
The association of the PON1 Q192R polymorphism with coronary heart disease: findings from the British Women's Heart and Health cohort study and a meta-analysisDebbie A Lawlor
Department of Social Medicine, University of Bristol, UK
BMC Genet 5:17. 2004..We have examined the association of the PON1 Q192R polymorphism with CHD in a large cohort of British women and combined the results from our cohort study with those from all other published studies...
Demographic shifts and medical trainingS Ebrahim
Department of Social Medicine, University of Bristol, Bristol BS8 2PR
BMJ 319:1358-60. 1999..Undergraduate medical education reforms are also forcing specific training in geriatric medicine out of the curriculums...
Social inequalities and disability in older men: prospective findings from the British regional heart studyShah Ebrahim
MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Soc Sci Med 59:2109-20. 2004..The likelihood of reporting disability between and within social class groups is influenced by material wealth...
Sexual intercourse and risk of ischaemic stroke and coronary heart disease: the Caerphilly studyS Ebrahim
Department of Social Medicine, University of Bristol, UK
J Epidemiol Community Health 56:99-102. 2002..To examine the relation between frequency of sexual intercourse and risk of ischaemic stroke and coronary heart disease...
Long-standing and limiting long-standing illness in older people: associations with chronic diseases, psychosocial and environmental factorsSalma Ayis
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Age Ageing 32:265-72. 2003..to examine the associations between domains of chronic diseases, social, psychological and environmental factors and long-standing and limiting long-standing illness among older people...
Locomotor disability in a cohort of British men: the impact of lifestyle and diseaseS Ebrahim
Department of Social Medicine, University of Bristol, UK
Int J Epidemiol 29:478-86. 2000....
Clustering of risk factors and social class in childhood and adulthood in British women's heart and health study: cross sectional analysisShah Ebrahim
Department of Social Medicine, University of Bristol, Canynge Hall, Bristol BS8 2PR
BMJ 328:861. 2004..To examine co-occurrence and clustering of risk factors used in the Framingham equation by social class in childhood and adult life...
The incidence and aetiology of stroke in the Caerphilly and Speedwell Collaborative Studies II: risk factors for ischaemic strokeP McCarron
Department of Social Medicine, University of Bristol, Bristol, UK
Public Health 115:12-20. 2001..Multivariate analyses revealed that, while there was some attenuation of the effect of social class, angina and elevated BP, the risks from atrial fibrillation and diabetes were increased...
Associations of measures of lung function with insulin resistance and Type 2 diabetes: findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Diabetologia 47:195-203. 2004..The aim of this study was to assess the associations of lung function with insulin resistance and Type 2 diabetes...
The detection, treatment and control of high blood pressure in older British adults: cross-sectional findings from the British Women's Heart and Health Study and the British Regional Heart StudyR Patel
Department of Social Medicine, University of Bristol, Bristol, UK
J Hum Hypertens 20:733-41. 2006..We conclude that targets of good control are rarely met in older individuals, who would benefit from the associated reduction in cardiovascular disease risk...
Associations of components of adult height with coronary heart disease in postmenopausal women: the British women's heart and health studyD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Heart 90:745-9. 2004..To assess the associations between components of adult height and coronary heart disease (CHD) in postmenopausal women...
Association between measures of morbidity and locomotor disability: diagnosis alone is not enoughJoy Adamson
Department of Social Medicine, University of Bristol, Canynge Hall, BS8 2PR Bristol, UK
Soc Sci Med 57:1355-60. 2003....
Association of birth weight with adult lung function: findings from the British Women's Heart and Health Study and a meta-analysisD A Lawlor
Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
Thorax 60:851-8. 2005....
Shaving, coronary heart disease, and stroke: the Caerphilly StudyShah Ebrahim
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, United Kingdom
Am J Epidemiol 157:234-8. 2003..The relation with stroke events remains unexplained by smoking or social factors...
Comparison of the associations of body mass index and measures of central adiposity and fat mass with coronary heart disease, diabetes, and all-cause mortality: a study using data from 4 UK cohortsAmy E Taylor
Department of Social Medicine, University of Bristol, Bristol, UK
Am J Clin Nutr 91:547-56. 2010..Measures of regional adiposity have been proposed as alternatives to the measurement of body mass index (BMI) for identifying persons at risk of future disease...
Aspirin use for the prevention of cardiovascular disease: the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR
Br J Gen Pract 51:743-5. 2001..Improvements in this area of medical practice are both necessary and feasible...
Geographical variation in cardiovascular disease, risk factors, and their control in older women: British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, UK
J Epidemiol Community Health 57:134-40. 2003..To measure the geographical variation in prevalence of cardiovascular disease, risk factors, and their control in a nationally representative sample of older British women...
Does the new International Diabetes Federation definition of the metabolic syndrome predict CHD any more strongly than older definitions? Findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Diabetologia 49:41-8. 2006..Our aim was to determine whether the magnitudes of the associations for any of the syndrome definitions are greater than for the individual components...
Associations of adult measures of childhood growth with breast cancer: findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Br J Cancer 89:81-7. 2003..93, 1.80). These associations were all independent of each other and other potential confounding factors and are likely to reflect different mechanisms by which factors operating prenatally and prepubertally influence breast cancer risk...
The metabolic syndrome and coronary heart disease in older women: findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Diabet Med 21:906-13. 2004..To compare two proposed definitions of the metabolic syndrome and to determine the clinical importance of the syndrome with respect to its association with coronary heart disease (CHD)...
The causes and effects of socio-demographic exclusions from clinical trialsC Bartlett
Medical Research Council Health Services Research Collaboration, Department of Social Medicine, University of Bristol, UK
Health Technol Assess 9:iii-iv, ix-x, 1-152. 2005....
Avoiding milk is associated with a reduced risk of insulin resistance and the metabolic syndrome: findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
Diabet Med 22:808-11. 2005..To examine the association of milk consumption with insulin resistance and the metabolic syndrome...
Temperature at birth, coronary heart disease, and insulin resistance: cross sectional analyses of the British women's heart and health studyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Heart 90:381-8. 2004..To assess the association of mean outdoor temperature around the time of birth with insulin resistance and coronary heart disease in later life...
The incidence and aetiology of stroke in the Caerphilly and Speedwell Collaborative Studies I: methods and incidence of eventsR Greenwood
Department of Social Medicine, University of Bristol, Bristol, UK
Public Health 115:4-11. 2001....
The associations between height components (leg and trunk length) and adult levels of liver enzymesA Fraser
Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
J Epidemiol Community Health 62:48-53. 2008....
Primary prevention of cardiovascular disease: a web-based risk score for seven British black and minority ethnic groupsP Brindle
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Heart 92:1595-602. 2006..To recalibrate an existing Framingham risk score to produce a web-based tool for estimating the 10-year risk of coronary heart disease (CHD) and cardiovascular disease (CVD) in seven British black and minority ethnic groups...
Self-reported smoking cessation interventions were not associated with quitting in older womenKnut Schroeder
Academic Unit of Primary Health Care, Department of Community Based Medicine, University of Bristol, Bristol, UK
J Clin Epidemiol 59:622-8. 2006....
Homogeneous assay of rs4343, an ACE I/D proxy, and an analysis in the British Women's Heart and Health Study (BWHHS)Mohammad Reza Abdollahi
Bristol Genetic Epidemiology Laboratory, University of Bristol, No 24 Tyndall Avenue, Bristol, BS8 1TQ, UK
Dis Markers 24:11-7. 2008..Liquid phase genotyping of SNP rs4343 may be preferable to gel based ACE I/D genotyping both for technical and functional reasons...
Association of C-reactive protein with blood pressure and hypertension: life course confounding and mendelian randomization tests of causalityGeorge Davey Smith
Department of Social Medicine, University of Bristol, Bristol, UK
Arterioscler Thromb Vasc Biol 25:1051-6. 2005....
Predicting catastrophic decline in mobility among older peopleS Ayis
MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
Age Ageing 35:382-7. 2006..to investigate the associations between chronic health conditions, psychosocial and environmental factors and catastrophic decline in mobility among older people...
The association of life course socio-economic position with diagnosis, treatment, control and survival of women with diabetes: findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Diabet Med 24:892-900. 2007..To examine the association of socio-economic position (SEP) with the diagnosis, treatment and control of diabetes, and with survival in women with and without Type 2 diabetes...
Birth weight is inversely associated with coronary heart disease in post-menopausal women: findings from the British women's heart and health studyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
J Epidemiol Community Health 58:120-5. 2004....
Serum cholesterol, haemorrhagic stroke, ischaemic stroke, and myocardial infarction: Korean national health system prospective cohort studyShah Ebrahim
Department of Social Medicine, University of Bristol, Bristol BS8 2PR
BMJ 333:22. 2006....
The association of smoking and cardiovascular disease in a population with low cholesterol levels: a study of 648,346 men from the Korean national health system prospective cohort studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Stroke 39:760-7. 2008..The effect of smoking on stroke subtypes is particularly unclear...
Associations of circulating C-reactive protein and interleukin-6 with cancer risk: findings from two prospective cohorts and a meta-analysisKatriina Heikkilä
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
Cancer Causes Control 20:15-26. 2009..We investigated the associations of circulating C-reactive protein (CRP) and interleukin-6 (IL-6) with cancer risk...
Cardiovascular disease risk assessment in older women: can we improve on Framingham? British Women's Heart and Health prospective cohort studyM May
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Heart 92:1396-401. 2006..To develop a cardiovascular risk assessment tool that is feasible and easy to use in primary care (general practice (GP) model)...
Smoking before the birth of a first child is not associated with increased risk of breast cancer: findings from the British Women's Heart and Health Cohort Study and a meta-analysisD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol BS7 8QA, UK
Br J Cancer 91:512-8. 2004..07 (0.94, 1.22). We conclude that smoking prior to the birth of a first child is not associated with increased risk of breast cancer...
Trends in hip and knee joint replacement: socioeconomic inequalities and projections of needT Dixon
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol BS8 2PR, UK
Ann Rheum Dis 63:825-30. 2004..There is a significant deprivation based gradient in rates. If current trends continue there would be almost 47 000 primary hip and 54 000 primary knee operations annually by 2010...
The thermolabile variant of MTHFR is associated with depression in the British Women's Heart and Health Study and a meta-analysisS J Lewis
Department of Social Medicine, University of Bristol, Whiteladies Road, Bristol, UK
Mol Psychiatry 11:352-60. 2006..36 (95% CI: 1.11, 1.67, P=0.003). Since this genotype influences the functioning of the folate metabolic pathway, these findings suggest that folate or its derivatives may be causally related to risk of depression...
The association between components of adult height and Type II diabetes and insulin resistance: British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, UK
Diabetologia 45:1097-106. 2002..The aim of this study was to investigate the associations between components of adult height (leg length, trunk length, ratio of leg to trunk length) and Type II (non-insulin-dependent) diabetes mellitus and insulin resistance...
Association between self-reported childhood socioeconomic position and adult lung function: findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Thorax 59:199-203. 2004..A study was undertaken to assess the associations between indicators of early life socioeconomic position and lung function in older adulthood...
Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participantsNicholas J Timpson
Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Department of Social Medicine, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, United Kingdom
Am J Clin Nutr 92:375-82. 2010..To date, there are no confirmed genetic correlates of circulating concentrations of L-ascorbic acid...
The association of socio-economic position across the life course and age at menopause: the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
BJOG 110:1078-87. 2003..The association between childhood deprivation and early menopause may at least in part be mediated via exposures, such as childhood diet, which affect both linear growth and age at menopause...
Performance of the WHO Rose angina questionnaire in post-menopausal women: are all of the questions necessary?D A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
J Epidemiol Community Health 57:538-41. 2003..To assess the performance of a shortened version of the Rose angina questionnaire focusing on exertional chest pain...
Is housework good for health? Levels of physical activity and factors associated with activity in elderly women. Results from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
J Epidemiol Community Health 56:473-8. 2002..To determine the prevalence of achieving new recommended levels of physical activity, the types of activity involved, and their determinants among elderly British women...
Association between offspring birth weight and atherosclerosis in middle aged men and women: British Regional Heart StudyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
J Epidemiol Community Health 57:462-3. 2003
Physical activity in older women: associations with area deprivation and with socioeconomic position over the life course: observations in the British Women's Heart and Health StudyM Hillsdon
Department of Exercise and Health Sciences, University of Bristol, Tyndall Avenue, Bristol BS8 1TP, UK
J Epidemiol Community Health 62:344-50. 2008..To assess the association between residential area-level deprivation, individual life-course socioeconomic position and adult levels of physical activity in older British women...
Sex matters: secular and geographical trends in sex differences in coronary heart disease mortalityD A Lawlor
Department of Social Medicine, University of Bristol, Bristol BS8 2PR
BMJ 323:541-5. 2001..To examine secular trends and geographical variations in sex differences in mortality from coronary heart disease and investigate how these relate to distributions in risk factors...
Systematic review of long term anticoagulation or antiplatelet treatment in patients with non-rheumatic atrial fibrillationF C Taylor
Bristol Heart Institute, University of Bristol, Bristol Royal Infirmary, Bristol BS2 8HW
BMJ 322:321-6. 2001..To examine the benefits and risks of long term anticoagulation (warfarin) compared with antiplatelet treatment (aspirin/indobufen) [corrected] in patients with non-rheumatic atrial fibrillation...
The association of oestrogen receptor alpha-haplotypes with cardiovascular risk factors in the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, UK
Eur Heart J 27:1597-604. 2006..We aimed to replicate these findings in a general population sample...
The association between graded physical activity in postmenopausal British women, and the prevalence and incidence of hip and wrist fracturesCelia L Gregson
Department of Social Medicine, University of Bristol, Bristol, UK
Age Ageing 39:565-74. 2010..The association between level of physical activity and prevalent and incident hip and wrist fractures was examined in a large representative sample of postmenopausal British women...
The association of the paraoxonase (PON1) Q192R polymorphism with depression in older women: findings from the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, UK
J Epidemiol Community Health 61:85-7. 2007..In the absence of such studies in non-occupational populations, these conclusions may not be valid...
Socio-economic position and the use of preventive health care in older British women: a cross-sectional study using data from the British Women's Heart and Health Study cohortRita Patel
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Fam Pract 24:7-10. 2007..Socio-economic inequalities in health may be due to differential uptake of preventive and therapeutic medical services...
Socioeconomic position in childhood and adulthood and insulin resistance: cross sectional survey using data from British women's heart and health studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol BS8 2PR
BMJ 325:805. 2002..To assess the associations between childhood and adulthood social class and insulin resistance...
C-reactive protein and its role in metabolic syndrome: mendelian randomisation studyNicholas J Timpson
Department of Social Medicine, University of Bristol, Canynge Hall, Bristol BS8 2PR, UK
Lancet 366:1954-9. 2005..Our aim was to generate estimates of the association between plasma CRP and metabolic syndrome phenotypes that were free from confounding and reverse causation, to assess the causal role of this protein...
Understanding long-standing illness among older peopleRachael Gooberman-Hill
MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, BS8 2PR, Bristol, UK
Soc Sci Med 56:2555-64. 2003..As such, both represent many facets of social and cultural life, and are best assessed as "trustworthy" rather than "truthful"...
Life course influences on insulin resistance: findings from the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, U K
Diabetes Care 26:97-103. 2003..To assess the independent associations of a broad range of early life risk factors and adult obesity with adult insulin resistance...
Is the association between parity and coronary heart disease due to biological effects of pregnancy or adverse lifestyle risk factors associated with child-rearing? Findings from the British Women's Heart and Health Study and the British Regional Heart StDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Circulation 107:1260-4. 2003..Parity is associated with coronary heart disease (CHD) risk. In the present study, we assessed the associations between number of children and CHD in both women and men...
Association between leg length and offspring birthweight: partial explanation for the trans-generational association between birthweight and cardiovascular disease: findings from the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Paediatr Perinat Epidemiol 17:148-55. 2003....
Association of body mass index measured in childhood, adolescence, and young adulthood with risk of ischemic heart disease and stroke: findings from 3 historical cohort studiesDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, United Kingdom
Am J Clin Nutr 83:767-73. 2006..It is unclear whether early life body mass index (BMI; in kg/m(2)) is associated with adult cardiovascular disease...
Associations of circulating C-reactive protein and interleukin-6 with survival in women with and without cancer: findings from the British Women's Heart and Health StudyKatriina Heikkilä
Department of Social Medicine, University of Bristol, University of Bristol, Bristol BS8 2PR, United Kingdom
Cancer Epidemiol Biomarkers Prev 16:1155-9. 2007....
Interleukin-18 polymorphism and physical functioning in older people: a replication study and meta-analysisKate Thomas
Department of Social Medicine, University of Bristol, Bristol BS8 2PS, UK
J Gerontol A Biol Sci Med Sci 64:1177-82. 2009..This variant has previously been associated with improved locomotor performance in old age, but the finding requires independent replication...
Association of the DRD2 gene Taq1A polymorphism and smoking behavior: a meta-analysis and new dataMarcus R Munafo
Department of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK
Nicotine Tob Res 11:64-76. 2009..There is a biological basis for considering that this association differs by sex, and differences in subpopulations might explain some of the contradictory evidence...
Lactase persistence-related genetic variant: population substructure and health outcomesGeorge Davey Smith
MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Bristol, UK
Eur J Hum Genet 17:357-67. 2009..19 (0.87, 1.64). The lactase persistence variant could contribute to the examination of data for the existence of, and then statistical control for, population substructure in genetic association studies...
The methylenetetrahydrofolate reductase C677T genotype and the risk of obesity in three large population-based cohortsSarah J Lewis
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS82PR, UK
Eur J Endocrinol 159:35-40. 2008..We sought to determine whether MTHFR C677T genotype was associated with obesity...
The association of insulin-like-growth factor 1 (IGF-1) with incident coronary heart disease in women: findings from the prospective British Women's Heart and Health StudyDebbie A Lawlor
MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, ul, UK
Atherosclerosis 201:198-204. 2008..To examine the association of insulin-like-growth factor 1 (IGF-1) with coronary heart disease (CHD) in women...
Does psychological distress predict the risk of ischemic stroke and transient ischemic attack? The Caerphilly StudyMargaret May
Department of Social Medicine, University of Bristol, UK
Stroke 33:7-12. 2002..Therefore, we examined whether psychological distress leads to an increased risk of ischemic stroke and transient ischemic attack (TIA)...
Associations of insulin-like growth factor (IGF)-I, IGF-II, IGF binding protein (IGFBP)-2 and IGFBP-3 with ultrasound measures of atherosclerosis and plaque stability in an older adult populationRichard M Martin
Department of Social Medicine, North Bristol, University of Bristol, Bristol BS8 2PR, United Kingdom
J Clin Endocrinol Metab 93:1331-8. 2008..Whether this association relates to alterations in plaque growth or stability, and the role of IGF-II and the major binding proteins [IGF binding protein (IGFBP)-2 and -3], is unclear...
The associations between birthweight and adult markers of liver damage and functionAbigail Fraser
Department of Social Medicine, University of Bristol, Bristol, UK
Paediatr Perinat Epidemiol 22:12-21. 2008....
Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiologyGeorge Davey Smith
Department of Social Medicine, University of Bristol, Bristol, United Kingdom
PLoS Med 4:e352. 2007....
Agreement between measured and self-reported weight in older women. Results from the British Women's Heart and Health StudyDebbie Anne Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Age Ageing 31:169-74. 2002..The cultural pressures that may cause the tendency among younger women to underestimate their weight, particularly when they are overweight, may operate differently in older women...
Gamma-glutamyltransferase is associated with incident vascular events independently of alcohol intake: analysis of the British Women's Heart and Health Study and Meta-AnalysisAbigail Fraser
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol BS8 2PR, UK
Arterioscler Thromb Vasc Biol 27:2729-35. 2007..Alanine aminotransferase (ALT) is the enzyme most closely associated with liver fat content...
Associations of von Willebrand factor, fibrin D-dimer and tissue plasminogen activator with incident coronary heart disease: British Women's Heart and Health cohort studyMargaret May
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, UK
Eur J Cardiovasc Prev Rehabil 14:638-45. 2007..It is not known, however, whether findings are generalizable to older women...
A systematic review of the association between circulating concentrations of C reactive protein and cancerKatriina Heikkilä
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, UK
J Epidemiol Community Health 61:824-33. 2007..Instead of further prevalent studies, more large prospective studies and CRP gene-cancer association studies would be valuable in investigating the role of CRP in cancer...
Determinants of reduced walking speed in people with musculoskeletal painSalma Ayis
Department of Social Medicine, University of Bristol, Bristol, UK
J Rheumatol 34:1905-12. 2007..People with musculoskeletal disease often have reduced walking speed. We investigated determinants of slower walking, other than musculoskeletal disease, that might provide valuable additional targets for therapy...
Folate supplementation and cardiovascular diseaseGeorge Davey Smith
Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
Lancet 366:1679-81. 2005
TAS2R38 (phenylthiocarbamide) haplotypes, coronary heart disease traits, and eating behavior in the British Women's Heart and Health StudyNic J Timpson
Department of Social Medicine, University of Bristol, United Kingdom
Am J Clin Nutr 81:1005-11. 2005..Recent observations have implicated 2 common haplotypes of TAS2R38 in the determination of bitter compound-tasting ability...
Commentary: the hormone replacement-coronary heart disease conundrum: is this the death of observational epidemiology?Debbie A Lawlor
Department of Social Medicine, University of Bristol, UK
Int J Epidemiol 33:464-7. 2004
What can mendelian randomisation tell us about modifiable behavioural and environmental exposures?George Davey Smith
Department of Social Medicine, University of Bristol, Bristol BS8 2PR
BMJ 330:1076-9. 2005
Association between childhood socioeconomic status and coronary heart disease risk among postmenopausal women: findings from the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, England
Am J Public Health 94:1386-92. 2004..We assessed the association between childhood socioeconomic status (SES) and coronary heart disease among postmenopausal women...
Is there a sex difference in the association between birth weight and systolic blood pressure in later life? Findings from a meta-regression analysisDebbie A Lawlor
Department of Social Medicine, University of Bristol, United Kingdom
Am J Epidemiol 156:1100-4. 2002..These findings suggest that reports of sex differences in the association between birth weight and blood pressure are chance findings...
Improving uptake and adherence in cardiac rehabilitation: literature reviewAndrew D Beswick
Department of Social Medicine, University of Bristol, Bristol, UK
J Adv Nurs 49:538-55. 2005..This paper presents a comprehensive systematic review of literature carried out to identify studies of interventions to improve uptake, adherence and professional compliance in cardiac rehabilitation...
Insulin resistance and depressive symptoms in middle aged men: findings from the Caerphilly prospective cohort studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol BS8 2PR
BMJ 330:705-6. 2005
Life-course socioeconomic position, area deprivation, and coronary heart disease: findings from the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, England
Am J Public Health 95:91-7. 2005..We sought to determine whether residential area deprivation, over and above the effect of life-course socioeconomic status or position (SEP), is associated with coronary heart disease...
Associations of parental, birth, and early life characteristics with systolic blood pressure at 5 years of age: findings from the Mater-University study of pregnancy and its outcomesDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, UK
Circulation 110:2417-23. 2004..We examined the associations of a range of parental and early life characteristics with systolic blood pressure at 5 years of age...
Gender and age inequity in the provision of coronary revascularisation in England in the 1990s: is it getting better?Mary Shaw
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Soc Sci Med 59:2499-507. 2004..Moreover, these inequities have remained constant through the study period. Possible explanations for this shortfall of provision are proposed...
Balancing benefits and harms: the example of non-steroidal anti-inflammatory drugsPaul Dieppe
Medical Research Council Health Services Research Collaboration, Department of Social Medicine, University of Bristol, Bristol BS8 2PR
BMJ 329:31-4. 2004
The challenge of secondary prevention for coronary heart disease in older patients: findings from the British Women's Heart and Health Study and the British Regional Heart StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR
Fam Pract 21:582-6. 2004..Secondary prevention of coronary heart disease (CHD) among older individuals is associated with considerable benefit...
Those confounded vitamins: what can we learn from the differences between observational versus randomised trial evidence?Debbie A Lawlor
Department of Social Medicine, University of Bristol, UK
Lancet 363:1724-7. 2004
Breastfeeding and atherosclerosis: intima-media thickness and plaques at 65-year follow-up of the Boyd Orr cohortRichard M Martin
Department of Social Medicine, University of Bristol, Bristol, UK
Arterioscler Thromb Vasc Biol 25:1482-8. 2005..The impact of breastfeeding in infancy on cardiovascular disease risk is uncertain. We related breastfeeding in infancy to atherosclerosis in adulthood...
The effect of definitions of activities of daily living on estimates of changing ability among older peopleSalma A Ayis
Department of Social Medicine, Bristol University, Bristol, UK
Int J Rehabil Res 30:39-46. 2007....
Does elevated plasma fibrinogen increase the risk of coronary heart disease? Evidence from a meta-analysis of genetic association studiesGeorge Davey Smith
Department of Social Medicine, Canynge Hall, Bristol BS8 2PR, United Kingdom
Arterioscler Thromb Vasc Biol 25:2228-33. 2005..The purpose of this study was to assess whether a genetic variant associated with higher fibrinogen levels is associated with increased coronary heart disease (CHD) risk, as a test of the causal influence of fibrinogen on CHD...
Adherence to long-term therapies: recent WHO report provides some answers but poses even more questionsKnut Schroeder
Division of Primary Health Care, University of Bristol, Cotham House, Cotham Hill, Bristol BS6 6JL, UK
J Clin Epidemiol 57:2-3. 2004
Adverse socioeconomic position across the lifecourse increases coronary heart disease risk cumulatively: findings from the British women's heart and health studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
J Epidemiol Community Health 59:785-93. 2005..To examine the associations of childhood and adult measurements of socioeconomic position with coronary heart disease (CHD) risk...
Mendelian randomization: prospects, potentials, and limitationsGeorge Davey Smith
Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol BS8 2PR
Int J Epidemiol 33:30-42. 2004
Hyperinsulinaemia and increased risk of breast cancer: findings from the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Cancer Causes Control 15:267-75. 2004..To assess the association between fasting insulin levels and breast cancer...
Accuracy and impact of risk assessment in the primary prevention of cardiovascular disease: a systematic reviewP Brindle
Department of Social Medicine, University of Bristol, UK
Heart 92:1752-9. 2006..To determine the accuracy of assessing cardiovascular disease (CVD) risk in the primary prevention of CVD and its impact on clinical outcomes...
Fibrinogen, C-reactive protein and coronary heart disease: does Mendelian randomization suggest the associations are non-causal?G Davey Smith
Department of Social Medicine, University of Bristol, Bristol, UK
QJM 97:163-6. 2004
Socioeconomic position, occupational exposures, and gender: the relation with locomotor disability in early old ageJ Adamson
Department of Social Medicine, University of Bristol, Bristol, UK
J Epidemiol Community Health 57:453-5. 2003
Provision, uptake and cost of cardiac rehabilitation programmes: improving services to under-represented groupsA D Beswick
Department of Social Medicine, University of Bristol, UK
Health Technol Assess 8:iii-iv, ix-x, 1-152. 2004..Regularly updated systematic reviews of relevant literature would also be useful...
