Brendan Doyle

Summary

Affiliation: University of Glasgow
Country: UK

Publications

  1. doi Pyrosequencing of DNA extracted from formalin-fixed paraffin-embedded tissue
    Brendan Doyle
    Beatson Institute for Cancer Research, Glasgow, UK
    Methods Mol Biol 724:181-90. 2011
  2. doi Sentinel lymph node biopsy in patients with a needle core biopsy diagnosis of ductal carcinoma in situ: is it justified?
    B Doyle
    Irish National Breast Screening Programme and Department of Histopathology, St Vincent s University Hospital, Dublin, Ireland
    J Clin Pathol 62:534-8. 2009
  3. doi p53 mutation and loss have different effects on tumourigenesis in a novel mouse model of pleomorphic rhabdomyosarcoma
    Brendan Doyle
    Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK
    J Pathol 222:129-37. 2010
  4. pmc Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53
    Paul Timpson
    The Beatson Institute for Cancer Research, Garscube Estate, Glasgow, United Kingdom
    Cancer Res 71:747-57. 2011
  5. ncbi Raf kinase inhibitor protein expression combined with peritoneal involvement and lymphovascular invasion predicts prognosis in Dukes' B colorectal cancer patients
    Brendan Doyle
    Beatson Institute for Cancer Research, Glasgow, UK
    Histopathology 62:505-10. 2013
  6. doi Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma
    Jennifer P Morton
    Beatson Institute for Cancer Research, Glasgow, United Kingdom
    Gastroenterology 139:292-303. 2010
  7. doi Mutant p53 drives invasion by promoting integrin recycling
    Patricia A J Muller
    The Beatson Institute for Cancer Research, Switchback Road, Bearsden, Glasgow G61 1BD, UK
    Cell 139:1327-41. 2009
  8. ncbi Liquid-based cytology improves productivity in cervical cytology screening
    B Doyle
    Department of Cytology, St Luke s Hospital, Dublin, Ireland
    Cytopathology 17:60-4. 2006

Collaborators

Detail Information

Publications8

  1. doi Pyrosequencing of DNA extracted from formalin-fixed paraffin-embedded tissue
    Brendan Doyle
    Beatson Institute for Cancer Research, Glasgow, UK
    Methods Mol Biol 724:181-90. 2011
    ..The technique is based on the bisulphite conversion of unmethylated cytosine to uracil and subsequent amplification by PCR. The technique is also appropriate for use on DNA extracted from formalin-fixed paraffin-embedded tissue...
  2. doi Sentinel lymph node biopsy in patients with a needle core biopsy diagnosis of ductal carcinoma in situ: is it justified?
    B Doyle
    Irish National Breast Screening Programme and Department of Histopathology, St Vincent s University Hospital, Dublin, Ireland
    J Clin Pathol 62:534-8. 2009
    ..DCIS is usually diagnosed non-operatively. Although sentinel lymph node biopsy (SNB) has become the standard of care for patients with invasive breast carcinoma, its use in patients with DCIS is controversial...
  3. doi p53 mutation and loss have different effects on tumourigenesis in a novel mouse model of pleomorphic rhabdomyosarcoma
    Brendan Doyle
    Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK
    J Pathol 222:129-37. 2010
    ..These data demonstrate that mutant p53 can co-operate with activated, mutant KRas to influence tumourigenesis and metastatic potential, over and above simple loss of normal protein function...
  4. pmc Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53
    Paul Timpson
    The Beatson Institute for Cancer Research, Garscube Estate, Glasgow, United Kingdom
    Cancer Res 71:747-57. 2011
    ....
  5. ncbi Raf kinase inhibitor protein expression combined with peritoneal involvement and lymphovascular invasion predicts prognosis in Dukes' B colorectal cancer patients
    Brendan Doyle
    Beatson Institute for Cancer Research, Glasgow, UK
    Histopathology 62:505-10. 2013
    ..New markers, identifying high-risk Dukes' B patients, are needed. Here, we examine the utility of Raf kinase inhibitor protein (RKIP) as such a marker and promoter methylation as a mechanism of RKIP down-regulation...
  6. doi Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma
    Jennifer P Morton
    Beatson Institute for Cancer Research, Glasgow, United Kingdom
    Gastroenterology 139:292-303. 2010
    ..The aim of this study was to assess the importance of Src in human PDAC and to use a genetically engineered mouse model of PDAC to determine the effects of dasatinib on PDAC progression...
  7. doi Mutant p53 drives invasion by promoting integrin recycling
    Patricia A J Muller
    The Beatson Institute for Cancer Research, Switchback Road, Bearsden, Glasgow G61 1BD, UK
    Cell 139:1327-41. 2009
    ..These findings open the possibility that blocking alpha5/beta1-integrin and/or the EGF receptor will have therapeutic benefit in mutant p53-expressing cancers...
  8. ncbi Liquid-based cytology improves productivity in cervical cytology screening
    B Doyle
    Department of Cytology, St Luke s Hospital, Dublin, Ireland
    Cytopathology 17:60-4. 2006
    ..Conclusions: The change to ThinPrep has improved productivity and decreased the number of unsatisfactory cases. There was no adverse effect on quality during the changeover...