Jenny L Donovan

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. pmc The intellectual challenges and emotional consequences of equipoise contributed to the fragility of recruitment in six randomized controlled trials
    Jenny L Donovan
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK Electronic address
    J Clin Epidemiol 67:912-20. 2014
  2. pmc Clear obstacles and hidden challenges: understanding recruiter perspectives in six pragmatic randomised controlled trials
    Jenny L Donovan
    School of Social and Community Medicine, University of Bristol, Canynge Hall, Bristol BS8 2PS, UK
    Trials 15:5. 2014
  3. pmc Presenting treatment options to men with clinically localized prostate cancer: the acceptability of active surveillance/monitoring
    Jenny L Donovan
    School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, UK
    J Natl Cancer Inst Monogr 2012:191-6. 2012
  4. pmc A review of reporting of participant recruitment and retention in RCTs in six major journals
    Merran Toerien
    Department of Sociology, The University of York, Heslington, York, YO10 4PS, UK
    Trials 10:52. 2009
  5. pmc Public involvement in suicide prevention: understanding and strengthening lay responses to distress
    Christabel Owens
    Peninsula Medical School Universities of Exeter and Plymouth, Wonford House, Dryden Road, Exeter, Devon, EX2 5AF, UK
    BMC Public Health 9:308. 2009
  6. pmc Screening for prostate cancer. The case against
    Jenny L Donovan
    University of Bristol, UK
    Ann R Coll Surg Engl 87:90-1; discussion 88. 2005
  7. pmc The case against
    Jenny L Donovan
    University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Ann R Coll Surg Engl 87:90-1. 2005
  8. doi Development of a complex intervention improved randomization and informed consent in a randomized controlled trial
    Jenny L Donovan
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
    J Clin Epidemiol 62:29-36. 2009
  9. pmc Impact of Helicobacter pylori eradication on dyspepsia, health resource use, and quality of life in the Bristol helicobacter project: randomised controlled trial
    J Athene Lane
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 332:199-204. 2006
  10. ncbi Prostate-specific antigen testing and prostate biopsy: are self-reported lower urinary tract symptoms and health-related quality of life associated with the decision to undergo these investigations?
    Kerry N L Avery
    Department of Social Medicine, University of Bristol, Bristol, UK
    BJU Int 102:1629-33. 2008

Detail Information

Publications65

  1. pmc The intellectual challenges and emotional consequences of equipoise contributed to the fragility of recruitment in six randomized controlled trials
    Jenny L Donovan
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK Electronic address
    J Clin Epidemiol 67:912-20. 2014
    ..The aim of the study was to investigate how doctors considered and experienced the concept of equipoise while recruiting patients to randomized controlled trials (RCTs)...
  2. pmc Clear obstacles and hidden challenges: understanding recruiter perspectives in six pragmatic randomised controlled trials
    Jenny L Donovan
    School of Social and Community Medicine, University of Bristol, Canynge Hall, Bristol BS8 2PS, UK
    Trials 15:5. 2014
    ..This study aimed i) to understand the recruitment process from the perspective of recruiters actively recruiting RCT participants in six pragmatic RCTs, and ii) to identify opportunities for interventions to improve recruitment...
  3. pmc Presenting treatment options to men with clinically localized prostate cancer: the acceptability of active surveillance/monitoring
    Jenny L Donovan
    School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, UK
    J Natl Cancer Inst Monogr 2012:191-6. 2012
    ....
  4. pmc A review of reporting of participant recruitment and retention in RCTs in six major journals
    Merran Toerien
    Department of Sociology, The University of York, Heslington, York, YO10 4PS, UK
    Trials 10:52. 2009
    ..This paper aims: (i) to update and extend previous reviews evaluating reporting of participant recruitment and retention in RCTs; (ii) to quantify the level of participation throughout RCTs...
  5. pmc Public involvement in suicide prevention: understanding and strengthening lay responses to distress
    Christabel Owens
    Peninsula Medical School Universities of Exeter and Plymouth, Wonford House, Dryden Road, Exeter, Devon, EX2 5AF, UK
    BMC Public Health 9:308. 2009
    ....
  6. pmc Screening for prostate cancer. The case against
    Jenny L Donovan
    University of Bristol, UK
    Ann R Coll Surg Engl 87:90-1; discussion 88. 2005
  7. pmc The case against
    Jenny L Donovan
    University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Ann R Coll Surg Engl 87:90-1. 2005
  8. doi Development of a complex intervention improved randomization and informed consent in a randomized controlled trial
    Jenny L Donovan
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
    J Clin Epidemiol 62:29-36. 2009
    ..Systematic reviews failed to identify robust strategies to improve recruitment. We developed and evaluated a complex intervention to increase levels of randomization and informed consent...
  9. pmc Impact of Helicobacter pylori eradication on dyspepsia, health resource use, and quality of life in the Bristol helicobacter project: randomised controlled trial
    J Athene Lane
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 332:199-204. 2006
    ..To determine the impact of a community based Helicobacter pylori screening and eradication programme on the incidence of dyspepsia, resource use, and quality of life, including a cost consequences analysis...
  10. ncbi Prostate-specific antigen testing and prostate biopsy: are self-reported lower urinary tract symptoms and health-related quality of life associated with the decision to undergo these investigations?
    Kerry N L Avery
    Department of Social Medicine, University of Bristol, Bristol, UK
    BJU Int 102:1629-33. 2008
    ..To investigate whether men's self-reported health-related quality of life and lower urinary tract symptoms (LUTS) are associated with acceptance of prostate-specific antigen (PSA) testing and subsequent prostate biopsy...
  11. ncbi Predictors of attendance for prostate-specific antigen screening tests and prostate biopsy
    Kerry N L Avery
    School of Social and Community Medicine, University of Bristol, Bristol, UK
    Eur Urol 62:649-55. 2012
    ..Little is known about factors influencing men's decisions to undergo screening and diagnostic tests for prostate cancer (PCa)...
  12. doi Do the risk factors of age, family history of prostate cancer or a higher prostate specific antigen level raise anxiety at prostate biopsy?
    Rhiannon C Macefield
    Department of Social Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    Eur J Cancer 45:2569-73. 2009
    ....
  13. ncbi Who can best recruit to randomized trials? Randomized trial comparing surgeons and nurses recruiting patients to a trial of treatments for localized prostate cancer (the ProtecT study)
    Jenny L Donovan
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Clin Epidemiol 56:605-9. 2003
    ..In a randomized trial nested within a trial of treatments for localized prostate cancer, we investigated the comparative effectiveness and cost-effectiveness of nurses and surgeons in recruiting patients...
  14. ncbi Men with prostate cancer make positive dietary changes following diagnosis and treatment
    Kerry N L Avery
    School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Clifton, Bristol, BS8 2PS, UK
    Cancer Causes Control 24:1119-28. 2013
    ..This study examined dietary changes in men before and after treatment for PC within the prostate testing for cancer and treatment randomized trial...
  15. pmc Circulating folate, vitamin B12, homocysteine, vitamin B12 transport proteins, and risk of prostate cancer: a case-control study, systematic review, and meta-analysis
    Simon M Collin
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Cancer Epidemiol Biomarkers Prev 19:1632-42. 2010
    ..Disturbed folate metabolism is associated with an increased risk of some cancers. Our objective was to determine whether blood levels of folate, vitamin B(12), and related metabolites were associated with prostate cancer risk...
  16. ncbi A comparison of socio-demographic and psychological factors between patients consenting to randomisation and those selecting treatment (the ProtecT study)
    Nicola Mills
    Department of Social Medicine, University of Bristol, UK
    Contemp Clin Trials 27:413-9. 2006
    ..Moreover, randomising patients with a preference may affect treatment efficacy and threaten internal validity...
  17. doi Associations of sexual dysfunction symptoms with PSA-detected localised and advanced prostate cancer: a case-control study nested within the UK population-based ProtecT (Prostate testing for cancer and Treatment) study
    Simon M Collin
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol BS8 2PS, UK
    Eur J Cancer 45:3254-61. 2009
    ..Conversely, among men with raised prostate-specific antigen (PSA) levels, a negative association might be expected if sexual dysfunction was symptomatic of benign, rather than malignant, prostatic disease...
  18. doi Factors distinguishing general practitioners who more readily participated in a large randomized trial were identified
    Liz Down
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Clin Epidemiol 62:67-73. 2009
    ..To investigate factors associated with the successful recruitment of general practices to a randomized controlled trial...
  19. doi Associations of lifestyle factors and anthropometric measures with repeat PSA levels during active surveillance/monitoring
    Anya J Burton
    MRC Centre for Causal Analysis in Translational Epidemiology, University of Bristol, Bristol, UK
    Cancer Epidemiol Biomarkers Prev 21:1877-85. 2012
    ..Factors that influence PSA growth, however, are unclear. We evaluated associations of anthropometric and lifestyle factors with age-related PSA growth...
  20. doi Psychological distress and prostate specific antigen levels in men with and without prostate cancer
    Emma L Turner
    Department of Social Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    Brain Behav Immun 23:1073-8. 2009
    ..These analyses highlight the need for further investigations into the possible role of depressed mood in the onset of prostate cancer and, in particular, research examining the biological basis for these relationships...
  21. pmc Exploring treatment preferences facilitated recruitment to randomized controlled trials
    Nicola Mills
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    J Clin Epidemiol 64:1127-36. 2011
    ..To explore how patients' treatment preferences were expressed and justified during recruitment to a randomized controlled trial (RCT) and how they influenced participation and treatment decisions...
  22. pmc Detection of prostate cancer in unselected young men: prospective cohort nested within a randomised controlled trial
    J Athene Lane
    Department of Social Medicine, University of Bristol
    BMJ 335:1139. 2007
    ..To investigate the feasibility of testing for prostate cancer and the prevalence and characteristics of the disease in unselected young men...
  23. ncbi Decision-making about PSA testing and prostate biopsies: a qualitative study embedded in a primary care randomised trial
    Kerry N L Avery
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Eur Urol 53:1186-93. 2008
    ..The overall aim was to increase understanding of men's decision-making about prostate-specific antigen (PSA) testing and subsequent biopsy...
  24. doi It's not just what you say, it's also how you say it: opening the 'black box' of informed consent appointments in randomised controlled trials
    Julia Wade
    Department of Social Medicine, University of Bristol, 39 Whatley Road, Clifton, Bristol BS8 2PS, United Kingdom
    Soc Sci Med 68:2018-28. 2009
    ..Use of these techniques is necessary to make potential participants' understanding of key issues and their position regarding equipoise explicit in order to facilitate truly informed consent...
  25. doi Associations of adiponectin and leptin with stage and grade of PSA-detected prostate cancer: the ProtecT study
    Anya Burton
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol, BS8 2PS, UK
    Cancer Causes Control 24:323-34. 2013
    ..We examined associations of the adipokines leptin and adiponectin with the stage and grade of PSA-detected prostate cancer...
  26. pmc Young adults' perceptions of GPs as a help source for mental distress: a qualitative study
    Lucy Biddle
    Department of Social Medicine, University of Bristol, Bristol, UK
    Br J Gen Pract 56:924-31. 2006
    ..Few young adults with mental disorder seek help from a GP.Aim:To explore young adults' perceptions of GPs as a source of help for mental distress...
  27. pmc The importance of dietary change for men diagnosed with and at risk of prostate cancer: a multi-centre interview study with men, their partners and health professionals
    Kerry N L Avery
    School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Clifton, Bristol BS8 2PS, UK
    BMC Fam Pract 15:81. 2014
    ..Focus groups also evaluated stakeholder opinion, including healthcare professionals, about the provision of dietary advice to PC patients...
  28. pmc Key issues in recruitment to randomised controlled trials with very different interventions: a qualitative investigation of recruitment to the SPARE trial (CRUK/07/011)
    Sangeetha Paramasivan
    School of Social and Community Medicine, University of Bristol, 39 Canynge Hall, Whatley Road, Bristol BS8 2PS, UK
    Trials 12:78. 2011
    ....
  29. pmc Using genetic proxies for lifecourse sun exposure to assess the causal relationship of sun exposure with circulating vitamin d and prostate cancer risk
    Carolina Bonilla
    School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, United Kingdom
    Cancer Epidemiol Biomarkers Prev 22:597-606. 2013
    ....
  30. pmc Alcohol consumption and PSA-detected prostate cancer risk--a case-control nested in the ProtecT study
    Luisa Zuccolo
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
    Int J Cancer 132:2176-85. 2013
    ....
  31. doi Population-based prostate-specific antigen testing in the UK leads to a stage migration of prostate cancer
    Alison L Moore
    Department of Social Medicine, University of Bristol, Bristol, UK
    BJU Int 104:1592-8. 2009
    ..To determine, within the UK, the stage and grade of prostate cancers that would be found through population-based prostate specific antigen (PSA) testing and biopsy...
  32. doi Association of diabetes mellitus with prostate cancer: nested case-control study (Prostate testing for cancer and treatment study)
    Emma L Turner
    Department of Social Medicine, University of Bristol, Bristol, UK
    Int J Cancer 128:440-6. 2011
    ..95). Diabetes is associated with a decreased risk of PSA-detected prostate cancer. These data add to the evidence of the association of diabetes with prostate cancer in the PSA era...
  33. doi A Peer Review Intervention for Monitoring and Evaluating sites (PRIME) that improved randomized controlled trial conduct and performance
    J Athene Lane
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    J Clin Epidemiol 64:628-36. 2011
    ..We aimed to develop a site monitoring process using peer reviewers to improve staff training, site performance, data collection, and GCP compliance...
  34. doi Associations of aspirin, nonsteroidal anti-inflammatory drug and paracetamol use with PSA-detected prostate cancer: findings from a large, population-based, case-control study (the ProtecT study)
    Ali S Murad
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Int J Cancer 128:1442-8. 2011
    ..Our conclusions are unlikely to be influenced by PSA detection bias because the inverse associations of aspirin, NSAID and paracetamol use with serum PSA would have attenuated (not generated) the observed positive associations...
  35. pmc Development of a new method for monitoring prostate-specific antigen changes in men with localised prostate cancer: a comparison of observational cohorts
    Kate Tilling
    Department of Social Medicine, Bristol University, Canynge Hall, Bristol, UK
    Eur Urol 57:446-52. 2010
    ..Prostate-specific antigen (PSA) measurements are increasingly used to monitor men with localised prostate cancer (PCa), but there is little consensus about the method to use...
  36. ncbi Transurethral prostate resection, noncontact laser therapy or conservative management in men with symptoms of benign prostatic enlargement? An economic evaluation
    Sian M Noble
    Department of Social Medicine, Medical Research Council Health Services Research Collaboration, Department of Social Medicine, University of Bristol, United Kingdom
    J Urol 168:2476-82. 2002
    ..We evaluated the cost-effectiveness of noncontact laser therapy compared with transurethral prostate resection and conservative treatment in men with symptoms associated with benign prostatic enlargement...
  37. doi Seasonal variation in prostate-specific antigen levels: a large cross-sectional study of men in the UK
    Liz Down
    School of Social and Community Medicine, University of Bristol, Bristol, Oncology Centre, Addenbrooke s Hospital, Cambridge, and Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, UK
    BJU Int 108:1409-14. 2011
    ..To assess whether a seasonal change in prostate specific antigen (PSA) levels can be detected in men recruited to a large clinical trial...
  38. pmc "Let's get the best quality research we can": public awareness and acceptance of consent to use existing data in health research: a systematic review and qualitative study
    Elizabeth M Hill
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol, UK
    BMC Med Res Methodol 13:72. 2013
    ..We also investigated the effect of the provision of detailed information about the potential effect of selection bias on public acceptability of the use of data for research...
  39. doi Associations of folate, vitamin B12, homocysteine, and folate-pathway polymorphisms with prostate-specific antigen velocity in men with localized prostate cancer
    Simon M Collin
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    Cancer Epidemiol Biomarkers Prev 19:2833-8. 2010
    ..We investigated whether these and other elements of folate metabolism were associated with prostate-specific antigen (PSA) velocity (PSAV) as a proxy measure of prostate cancer progression in men with localized prostate cancer...
  40. ncbi Perceptions of equipoise are crucial to trial participation: a qualitative study of men in the ProtecT study
    Nicola Mills
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, United Kingdom
    Control Clin Trials 24:272-82. 2003
    ..A priority for future research is to focus on the provision and presentation of suitable and effective trial information, concentrating in particular on the neglected concept of clinical equipoise...
  41. doi Very low PSA concentrations and deletions of the KLK3 gene
    Santiago Rodriguez
    MRC Centre for Causal Analyses in Translational Epidemiology CAiTE and Bristol Genetic Epidemiology Laboratories BGEL, University of Bristol, Bristol, UK
    Clin Chem 59:234-44. 2013
    ..We hypothesized that very low PSA concentrations might reflect gene-inactivating mutations in KLK3 that lead to abnormally reduced gene expression...
  42. ncbi Satisfaction with care: an independent outcome measure in surgical oncology
    Kerry N L Avery
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol Royal Infirmary, BS8 2PR, United Kingdom
    Ann Surg Oncol 13:817-22. 2006
    ..This study examined how patient satisfaction related to surgical morbidity, treatment type, and QOL outcomes after inpatient treatment for upper gastrointestinal cancer...
  43. pmc The feasibility of a randomized controlled trial of esophagectomy for esophageal cancer - the ROMIO (Randomized Oesophagectomy: Minimally Invasive or Open) study: protocol for a randomized controlled trial
    Kerry Nl Avery
    School of Social and Community Medicine, University of Bristol, 39 Whatley Road, BS8 2PS, Clifton Bristol, UK
    Trials 15:200. 2014
    ....
  44. doi Behavior theory for dietary interventions for cancer prevention: a systematic review of utilization and effectiveness in creating behavior change
    Kerry N L Avery
    School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol BS8 2PS, UK
    Cancer Causes Control 24:409-20. 2013
    ..This systematic review examined application of behavior theory to dietary interventions aimed at preventing cancer to improve the design and interpretation of trials...
  45. ncbi A scored form of the Bristol Female Lower Urinary Tract Symptoms questionnaire: data from a randomized controlled trial of surgery for women with stress incontinence
    Sara T Brookes
    Department of Social Medicine, University of Bristol, UK
    Am J Obstet Gynecol 191:73-82. 2004
    ..This paper describes development and validation of a scored form BFLUTS questionnaire...
  46. ncbi Health-related quality of life during neoadjuvant treatment and surgery for localized esophageal carcinoma
    Jane M Blazeby
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Cancer 103:1791-9. 2005
    ..The current study examined HRQL during preoperative chemotherapy/chemoradiotherapy treatment and compared postoperative recovery of HRQL in patients undergoing combined treatment with patients undergoing surgery alone...
  47. pmc Sexual dysfunction in men after treatment for lower urinary tract symptoms: evidence from randomised controlled trial
    Sara T Brookes
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol BS8 2PR
    BMJ 324:1059-61. 2002
    ..To examine the impact on sexual function of treatments for lower urinary tract symptoms in men...
  48. pmc Supporting adolescent emotional health in schools: a mixed methods study of student and staff views in England
    Judi Kidger
    Department of Social Medicine, University of Bristol, Canynge Hall, 39, Whatley Road, Bristol BS8 2PS, UK
    BMC Public Health 9:403. 2009
    ..Relatively little is known about student and staff views regarding current school-based emotional health provision and what they would like to see in the future, and this is what this study explored...
  49. ncbi Relationship between lower urinary tract symptoms and erectile dysfunction: results from the Boston Area Community Health Survey
    Sara T Brookes
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    J Urol 179:250-5; discussion 255. 2008
    ..We explored the association of lower urinary tract symptoms and erectile dysfunction in a racially and ethnically diverse random sample of men...
  50. pmc Comparing specialist medical care with specialist medical care plus the Lightning ProcessĀ® for chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME): study protocol for a randomised controlled trial (SMILE Trial)
    Esther Crawley
    Centre for Child and Adolescent Health, School of Social and Community Medicine, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Trials 14:444. 2013
    ..Although over 250 children with CFS/ME attend LP courses each year, there are no reported studies on the effectiveness or cost-effectiveness...
  51. pmc Unstated factors in orthopaedic decision-making: a qualitative study
    Rachael Gooberman-Hill
    University of Bristol, School of Clinical Sciences, Southmead Hospital, Westbury on Trym, Bristol BS10 5NB, UK
    BMC Musculoskelet Disord 11:213. 2010
    ..However, we do not know what happens within orthopaedic practice and whether this reflects the shared model. Our study examined how decisions are made about TJR in orthopaedic consultations...
  52. pmc Factors influencing help seeking in mentally distressed young adults: a cross-sectional survey
    Lucy Biddle
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Br J Gen Pract 54:248-53. 2004
    ..Young adults, especially men, are among those least likely to consult healthcare professionals when mentally distressed or suicidal...
  53. ncbi A placebo-controlled randomized trial of eradication of Helicobacter pylori in the general population: study design and response rates of the Bristol Helicobacter Project
    J Athene Lane
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Control Clin Trials 23:321-32. 2002
    ..In the Bristol Helicobacter Project the rate of participation varied inversely with both social deprivation and the prevalence of the infection...
  54. ncbi Research in black and white
    Joy Adamson
    Joint Medical Research Council, Department of Health, University of Bristol, UK
    Qual Health Res 12:816-25. 2002
    ..The authors believe that qualitative research should be judged by the plausibility of the findings and by a critical evaluation of the way in which the research was conducted and the reflexivity of the researcher...
  55. ncbi "Why don't they just tell me straight, why allocate it?" The struggle to make sense of participating in a randomised controlled trial
    Katie Featherstone
    Cardiff School of Social Sciences, Cardiff University, Wales, UK
    Soc Sci Med 55:709-19. 2002
    ..The provision of clearer written information or time to discuss the trial with particular individuals might be beneficial, although greater public understanding of trials is also needed...
  56. ncbi Inverse relationship between alcohol consumption and active Helicobacter pylori infection: the Bristol Helicobacter project
    Liam J Murray
    The Queen s University of Belfast, United Kingdom
    Am J Gastroenterol 97:2750-5. 2002
    ..The aim of this study was to examine whether smoking or consumption of alcohol or coffee is associated with active Helicobacter pylori (H. pylori) infection...
  57. ncbi Remapping the body: learning to eat again after surgery for esophageal cancer
    David Wainwright
    University of Bath, United Kingdom
    Qual Health Res 17:759-71. 2007
    ..The authors report findings from in-depth interviews with 11 esophageal cancer patients, documenting their experiences as they struggle to achieve a process of adaptation that is at once physiological, psychological, and social...
  58. ncbi Contribution of a single repeat PSA test to prostate cancer risk assessment: experience from the ProtecT study
    Derek J Rosario
    University of Sheffield, Sheffield, United Kingdom
    Eur Urol 53:777-84. 2008
    ..To examine whether a single repeat prostate-specific antigen (PSA) helps discriminate cancer from non-cancer-related PSA elevation...
  59. ncbi Measuring the psychosocial impact of population-based prostate-specific antigen testing for prostate cancer in the UK
    Lucy A Brindle
    School of Nursing and Midwifery, University of Southampton, Southampton, UK
    BJU Int 98:777-82. 2006
    ....
  60. pmc Randomised controlled trial of effects of Helicobacter pylori infection and its eradication on heartburn and gastro-oesophageal reflux: Bristol helicobacter project
    Richard F Harvey
    Frenchay Hospital, North Bristol NHS Trust, Bristol BS16 1LE
    BMJ 328:1417. 2004
    ..To investigate the effects of Helicobacter pylori infection and its eradication on heartburn and gastro-oesophageal reflux...
  61. ncbi A patient-centered approach to developing a comprehensive symptom and quality of life assessment of anal incontinence
    Nikki Cotterill
    Bristol Urological Institute, Southmead Hospital, Westbury on Trym, Bristol, United Kingdom
    Dis Colon Rectum 51:82-7. 2008
    ..This study was designed to identify question items required for a comprehensive symptom and quality of life assessment for individuals with anal incontinence...
  62. pmc Multiple loci with different cancer specificities within the 8q24 gene desert
    Maya Ghoussaini
    Cancer Research UK Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, CB1 8RN, Cambridge, UK
    J Natl Cancer Inst 100:962-6. 2008
    ..We conclude that there are at least five separate functional variants in this region...
  63. pmc Ethics of clinical trials from bayesian perspective: randomisation to clinical trials may solve dilemma of treatment choice in prostate cancer
    Freddie C Hamdy
    BMJ 326:1456. 2003
  64. ncbi Serum insulin-like growth factor-I is positively associated with serum prostate-specific antigen in middle-aged men without evidence of prostate cancer
    Steven E Oliver
    Department of Health Sciences, University of York, and The Hull York Medical School, Heslington, York, UK
    Cancer Epidemiol Biomarkers Prev 13:163-5. 2004
    ..Greater rates of cell proliferation induced by IGF-I may be a key biological pathway underlying these disorders...
  65. doi Multiple newly identified loci associated with prostate cancer susceptibility
    Rosalind A Eeles
    The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK
    Nat Genet 40:316-21. 2008
    ..7 x 10(-29)). We confirmed previous reports of common loci associated with prostate cancer at 8q24 and 17q. Moreover, we found that three of the newly identified loci contain candidate susceptibility genes: MSMB, LMTK2 and KLK3...