A J Doherty

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. pmc Antagonist activity of alpha-substituted 4-carboxyphenylglycine analogues at group I metabotropic glutamate receptors expressed in CHO cells
    A J Doherty
    Department of Anatomy, School of Medical Sciences, University of Bristol, England, UK
    Br J Pharmacol 126:205-10. 1999
  2. pmc A novel, competitive mGlu(5) receptor antagonist (LY344545) blocks DHPG-induced potentiation of NMDA responses but not the induction of LTP in rat hippocampal slices
    A J Doherty
    MRC Centre for Synaptic Plasticity, Department of Anatomy, School of Medical Sciences, University of Bristol, University Walk, Bristol, BS8 1TD
    Br J Pharmacol 131:239-44. 2000
  3. ncbi request reprint The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity
    S M Fitzjohn
    Department of Anatomy, University of Bristol, UK
    Neuropharmacology 37:1445-58. 1998

Detail Information

Publications3

  1. pmc Antagonist activity of alpha-substituted 4-carboxyphenylglycine analogues at group I metabotropic glutamate receptors expressed in CHO cells
    A J Doherty
    Department of Anatomy, School of Medical Sciences, University of Bristol, England, UK
    Br J Pharmacol 126:205-10. 1999
    ..5. These phenylglycine analogues could provide leads for the development of subtype selective antagonists...
  2. pmc A novel, competitive mGlu(5) receptor antagonist (LY344545) blocks DHPG-induced potentiation of NMDA responses but not the induction of LTP in rat hippocampal slices
    A J Doherty
    MRC Centre for Synaptic Plasticity, Department of Anatomy, School of Medical Sciences, University of Bristol, University Walk, Bristol, BS8 1TD
    Br J Pharmacol 131:239-44. 2000
    ..6. These results further indicate that mGlu receptor-mediated potentiation of NMDA responses is not essential for the induction of LTP...
  3. ncbi request reprint The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity
    S M Fitzjohn
    Department of Anatomy, University of Bristol, UK
    Neuropharmacology 37:1445-58. 1998
    ..Since in the same inputs these forms of LTP were blocked by (S)-MCPG, a novel type of mGlu receptor may be involved in their induction...