Paul D Dobson

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. ncbi Integration of metabolic databases for the reconstruction of genome-scale metabolic networks
    Karin Radrich
    Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK
    BMC Syst Biol 4:114. 2010
  2. ncbi 'Metabolite-likeness' as a criterion in the design and selection of pharmaceutical drug libraries
    Paul D Dobson
    School of Chemistry and The Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess St, Manchester M1 7DN, UK
    Drug Discov Today 14:31-40. 2009
  3. ncbi Implications of the dominant role of transporters in drug uptake by cells
    Paul D Dobson
    School of Chemistry and Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess Street, Manchester M17DN, UK
    Curr Top Med Chem 9:163-81. 2009
  4. ncbi Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only
    Douglas B Kell
    School of Chemistry, The University of Manchester, 131 Princess St, Manchester, M1 7DN, UK
    Drug Discov Today 16:704-14. 2011
  5. ncbi Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?
    Paul D Dobson
    School of Chemistry and Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    Nat Rev Drug Discov 7:205-20. 2008
  6. ncbi Further developments towards a genome-scale metabolic model of yeast
    Paul D Dobson
    School of Chemistry, The University of Manchester, Manchester M13 9PL, UK
    BMC Syst Biol 4:145. 2010
  7. ncbi A simple approach to normalization for spectroscopic data mining
    Paul D Dobson
    Faculty of Life Sciences, The University of Manchester, Sackville Street, P.O. Box 88, Manchester M60 1QD, UK
    Appl Spectrosc 59:542-4. 2005

Collaborators

Detail Information

Publications7

  1. ncbi Integration of metabolic databases for the reconstruction of genome-scale metabolic networks
    Karin Radrich
    Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK
    BMC Syst Biol 4:114. 2010
    ..This process is further complicated by occurrences of missing or conflicting information and the absence of common annotation standards between different data sources...
  2. ncbi 'Metabolite-likeness' as a criterion in the design and selection of pharmaceutical drug libraries
    Paul D Dobson
    School of Chemistry and The Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess St, Manchester M1 7DN, UK
    Drug Discov Today 14:31-40. 2009
    ....
  3. ncbi Implications of the dominant role of transporters in drug uptake by cells
    Paul D Dobson
    School of Chemistry and Manchester Interdisciplinary Biocentre, The University of Manchester, 131 Princess Street, Manchester M17DN, UK
    Curr Top Med Chem 9:163-81. 2009
    ..Finally, the central importance of computational modelling of transporter substrate preferences by structure-activity relationships is discussed...
  4. ncbi Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only
    Douglas B Kell
    School of Chemistry, The University of Manchester, 131 Princess St, Manchester, M1 7DN, UK
    Drug Discov Today 16:704-14. 2011
    ..The recognition that drugs necessarily require carriers for uptake into cells provides many opportunities for improving the effectiveness of the drug discovery process...
  5. ncbi Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?
    Paul D Dobson
    School of Chemistry and Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    Nat Rev Drug Discov 7:205-20. 2008
    ....
  6. ncbi Further developments towards a genome-scale metabolic model of yeast
    Paul D Dobson
    School of Chemistry, The University of Manchester, Manchester M13 9PL, UK
    BMC Syst Biol 4:145. 2010
    ....
  7. ncbi A simple approach to normalization for spectroscopic data mining
    Paul D Dobson
    Faculty of Life Sciences, The University of Manchester, Sackville Street, P.O. Box 88, Manchester M60 1QD, UK
    Appl Spectrosc 59:542-4. 2005