Snezana Djordjevic

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Crystal structure of tobacco etch virus protease shows the protein C terminus bound within the active site
    Christine M Nunn
    Department of Biochemistry and Molecular Biology, University College London, Gower Street, London, WC1E 6BT, UK
    J Mol Biol 350:145-55. 2005
  2. pmc Crystal structures of PI3K-C2alpha PX domain indicate conformational change associated with ligand binding
    Gary N Parkinson
    Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, 29 39 Brunswick Square, London WC1N 1AX, UK
    BMC Struct Biol 8:13. 2008
  3. ncbi request reprint Structural insight into substrate specificity and regulatory mechanisms of phosphoinositide 3-kinases
    Snezana Djordjevic
    Bloomsbury Centre for Structural Biology and Department of Biochemistry and Molecular Biology, University College London, London, UK WC1E 6BT
    Trends Biochem Sci 27:426-32. 2002
  4. doi request reprint Structural insights into the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I)
    Shreenal Patel
    Institute of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6BT, UK
    Biochem J 425:513-22. 2010
  5. pmc Production of soluble human vascular endothelial growth factor VEGF-A165-heparin binding domain in Escherichia coli
    Arefeh Seyedarabi
    Institute of Structural and Molecular Biology, University College London, London, UK
    PLoS ONE 8:e55690. 2013
  6. doi request reprint Characterization of a two-component signal transduction system that controls arsenite oxidation in the chemolithoautotroph NT-26
    Sunita Sardiwal
    Division of Biosciences, Institute of Structural and Molecular Biology, University College London, London, UK
    FEMS Microbiol Lett 313:20-8. 2010
  7. ncbi request reprint The mechanism of Mycobacterium tuberculosis alkylhydroperoxidase AhpD as defined by mutagenesis, crystallography, and kinetics
    Aleksey Koshkin
    Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143 2280, USA
    J Biol Chem 278:29502-8. 2003
  8. ncbi request reprint The crystal structure of Mycobacterium tuberculosis alkylhydroperoxidase AhpD, a potential target for antitubercular drug design
    Christine M Nunn
    Department of Biochemistry and Molecular Biology, University College, Gower Street, London WC1E 6BT, United Kingdom
    J Biol Chem 277:20033-40. 2002
  9. pmc Discrimination between different methylation states of chemotaxis receptor Tar by receptor methyltransferase CheR
    Eduardo Perez
    Center for Advanced Biotechnology and Medicine, Department of Biochemistry, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Biochemistry 43:953-61. 2004

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Crystal structure of tobacco etch virus protease shows the protein C terminus bound within the active site
    Christine M Nunn
    Department of Biochemistry and Molecular Biology, University College London, Gower Street, London, WC1E 6BT, UK
    J Mol Biol 350:145-55. 2005
    ..Data suggest that TEV protease could be inhibited by the peptide product of autolysis. Separate modes of recognition for native substrates and the site of TEV protease self-cleavage are proposed...
  2. pmc Crystal structures of PI3K-C2alpha PX domain indicate conformational change associated with ligand binding
    Gary N Parkinson
    Cancer Research UK Biomolecular Structure Group, The School of Pharmacy, University of London, 29 39 Brunswick Square, London WC1N 1AX, UK
    BMC Struct Biol 8:13. 2008
    ..All PX domains contain a canonical core structure with main differences exhibited within the loop regions forming the phosphoinositide binding pockets. It is within these areas that the molecular basis for ligand specificity originates...
  3. ncbi request reprint Structural insight into substrate specificity and regulatory mechanisms of phosphoinositide 3-kinases
    Snezana Djordjevic
    Bloomsbury Centre for Structural Biology and Department of Biochemistry and Molecular Biology, University College London, London, UK WC1E 6BT
    Trends Biochem Sci 27:426-32. 2002
    ..Ongoing comprehensive structural and functional studies are essential to realize the promise of PI3K isozyme-specific therapeutic agents...
  4. doi request reprint Structural insights into the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I)
    Shreenal Patel
    Institute of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6BT, UK
    Biochem J 425:513-22. 2010
    ....
  5. pmc Production of soluble human vascular endothelial growth factor VEGF-A165-heparin binding domain in Escherichia coli
    Arefeh Seyedarabi
    Institute of Structural and Molecular Biology, University College London, London, UK
    PLoS ONE 8:e55690. 2013
    ..The ability to produce significant quantities of a soluble active form of VEGF-A(165)-HBD will enable further studies addressing the role of VEGF-A in essential processes such as angiogenesis, vasculogenesis and vascular permeability...
  6. doi request reprint Characterization of a two-component signal transduction system that controls arsenite oxidation in the chemolithoautotroph NT-26
    Sunita Sardiwal
    Division of Biosciences, Institute of Structural and Molecular Biology, University College London, London, UK
    FEMS Microbiol Lett 313:20-8. 2010
    ..Lastly, arsenite sensing does not appear to involve thiol chemistry...
  7. ncbi request reprint The mechanism of Mycobacterium tuberculosis alkylhydroperoxidase AhpD as defined by mutagenesis, crystallography, and kinetics
    Aleksey Koshkin
    Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143 2280, USA
    J Biol Chem 278:29502-8. 2003
    ..The collective results strongly support the proposed catalytic mechanism for AhpD...
  8. ncbi request reprint The crystal structure of Mycobacterium tuberculosis alkylhydroperoxidase AhpD, a potential target for antitubercular drug design
    Christine M Nunn
    Department of Biochemistry and Molecular Biology, University College, Gower Street, London WC1E 6BT, United Kingdom
    J Biol Chem 277:20033-40. 2002
    ..tuberculosis biology...
  9. pmc Discrimination between different methylation states of chemotaxis receptor Tar by receptor methyltransferase CheR
    Eduardo Perez
    Center for Advanced Biotechnology and Medicine, Department of Biochemistry, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Biochemistry 43:953-61. 2004
    ..It is likely that this complementarity is involved in discriminating different methylation states of the receptors...