Research Topics
| Kate E DingleSummaryAffiliation: University of Oxford Country: UK Publications
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Detail Information
Publications
Molecular characterization of Campylobacter jejuni clones: a basis for epidemiologic investigationKate E Dingle
Department of Zoology, University of Oxford, United Kingdom
Emerg Infect Dis 8:949-55. 2002..These data demonstrate that the clonal complex, as defined by MLST, is an epidemiologically relevant unit for both long and short-term investigations of C. jejuni epidemiology...- Sequence typing and comparison of population biology of Campylobacter coli and Campylobacter jejuniKate E Dingle
Nuffield Department of Clinical Sciences, Oxford University, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
J Clin Microbiol 43:340-7. 2005..The use of a common MLST scheme allows direct comparisons of the population biology and molecular epidemiology of these two closely related human pathogens... - Multilocus sequence typing of Clostridium difficileDavid Griffiths
Nuffield Department of Clinical Medicine, Oxford University, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
J Clin Microbiol 48:770-8. 2010..difficile in total stool DNA extracts without isolate culture. The direct (nonculture) MLST approach may prove useful as a rapid genotyping method, potentially benefiting individual patients and informing hospital infection control... - Clinical Clostridium difficile: clonality and pathogenicity locus diversityKate E Dingle
Nuffield Department of Clinical Laboratory Sciences, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom
PLoS ONE 6:e19993. 2011.... - Genetic relationships among reptilian and mammalian Campylobacter fetus strains determined by multilocus sequence typingKate E Dingle
Nuffield Department of Clinical Laboratory Sciences, Oxford University, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
J Clin Microbiol 48:977-80. 2010..fetus, and there was evidence of recombination among members of these two groups. The reptile group represents a possible separate genomospecies capable of infecting humans... - Stable and noncompetitive RNA internal control for routine clinical diagnostic reverse transcription-PCRKate E Dingle
Nuffield Department of Clinical Sciences, Oxford University, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
J Clin Microbiol 42:1003-11. 2004..During routine testing of 324 consecutive unselected respiratory samples, the presence of the internal control ensured that genuine and false-negative results were distinguishable, thus increasing the diagnostic confidence in the assay... - Mutation in a Lordsdale norovirus epidemic strain as a potential indicator of transmission routesKate E Dingle
Nuffield Department of Clinical Sciences, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom, OX3 9DU
J Clin Microbiol 42:3950-7. 2004..4 to 13.6% in the outer P2 domain of the capsid, which also had a single-amino-acid insertion. Alterations to the capsid structure compared to previous noroviruses may explain the increased number of outbreaks during 2002 and 2003... - Predictors of first recurrence of Clostridium difficile infection: implications for initial managementDavid W Eyre
NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK
Clin Infect Dis 55:S77-87. 2012..Risk factors, including increasing age, initial disease severity, and hospital exposure, predict CDI recurrence and identify patients likely to benefit from enhanced initial CDI treatment... - Molecular epidemiology of Clostridium difficile strains in children compared with that of strains circulating in adults with Clostridium difficile-associated infectionNicole Stoesser
Nuffield Department of Clinical Medicine, Oxford University, John Radcliffe Hospital, Oxford OX3 9DU, UK
J Clin Microbiol 49:3994-6. 2011..difficile-associated infections studied (n = 83). No children carried hypervirulent PCR ribotype 027. Children could participate in the transmission of some adult disease-causing genotypes... - Clostridium difficile mixed infection and reinfectionDavid W Eyre
NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom
J Clin Microbiol 50:142-4. 2012..Of 109 sample pairs taken on the same day, 3 (3%) had different genotypes. Considering samples 0 to 7 days apart as the same CDI, 7% of cases had mixed infections with >1 genotype... - Characterisation of Clostridium difficile hospital ward-based transmission using extensive epidemiological data and molecular typingA Sarah Walker
National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom
PLoS Med 9:e1001172. 2012..This study aimed to investigate ward-based transmission of C. difficile, by subdividing outbreaks into distinct lineages defined by multi-locus sequence typing (MLST)... - Extended sequence typing of Campylobacter spp., United KingdomKate E Dingle
John Radcliffe Hospital, Oxford, UK
Emerg Infect Dis 14:1620-2. 2008..975 to 0.992 among 620 clinical isolates from Oxfordshire, United Kingdom. This enhanced typing scheme enabled identification of clusters and retained data required for long-range epidemiologic comparisons of isolates... 
Host-associated genetic import in Campylobacter jejuniNoel D McCarthy
Department of Zoology, University of Oxford, Oxford, United Kingdom
Emerg Infect Dis 13:267-72. 2007..Assignment using this signature enables improved prediction of source for pathogens that undergo frequent genetic recombination...- A longitudinal 6-year study of the molecular epidemiology of clinical campylobacter isolates in Oxfordshire, United kingdomAlison J Cody
Department of Zoology, University of Oxford, Oxford, UK
J Clin Microbiol 50:3193-201. 2012..These data also demonstrated that detailed surveillance at a single site captures information which reflects that observed nationally... - Clonal nature of Campylobacter fetus as defined by multilocus sequence typingMarcel A P Van Bergen
Animal Sciences Group, Division of Infectious Diseases, P.O. Box 65, 8200 AB Lelystad, The Netherlands
J Clin Microbiol 43:5888-98. 2005..Congruence was observed among C. fetus subspecies, sap type, and ST; therefore, MLST confirms that mammalian C. fetus is genetically stable, probably as result of the introduction of a single ancestral clone into a mammalian niche... - Molecular evidence for dissemination of unique Campylobacter jejuni clones in Curaçao, Netherlands AntillesBirgitta Duim
Department of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands
J Clin Microbiol 41:5593-7. 2003..Furthermore, given the observation that C. jejuni-associated diseases appear to be more severe from November to February, it can be speculated that this may be due to the presence of virulent clones with a limited span of circulation... - Comparative genotyping of Campylobacter jejuni by amplified fragment length polymorphism, multilocus sequence typing, and short repeat sequencing: strain diversity, host range, and recombinationLeo M Schouls
Research Laboratory for Infectious Diseases, National Institute of Public Health and the Environment, Bilthoven, The Netherlands
J Clin Microbiol 41:15-26. 2003....