Yunchuan Ding

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9
    Yunchuan Ding
    Transplantation Research Immunology Group, Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Diabetes 58:1797-806. 2009
  2. pmc Mesenchymal stem-cell immunosuppressive capabilities: therapeutic implications in islet transplantation
    Yunchuan Ding
    Transplantation Research Immunology Group, Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    Transplantation 89:270-3. 2010
  3. pmc Matrix metalloproteinase-9 regulates tumor cell invasion through cleavage of protease nexin-1
    Danmei Xu
    Gray Institute of Radiation Oncology and Biology, University of Oxford, Oxford, UK
    Cancer Res 70:6988-98. 2010
  4. pmc Protease nexin 1 induces apoptosis of prostate tumor cells through inhibition of X-chromosome-linked inhibitor of apoptosis protein
    Chad M McKee
    Gray Institute of Radiation Oncology and Biology, Medical Science Division, University of Oxford, Oxford, United Kingdom
    Oncotarget 6:3784-96. 2015
  5. pmc Adiponectin receptor signaling on dendritic cells blunts antitumor immunity
    Peng H Tan
    Genetic Engineering Laboratory, College of Biotechnology, Xi An University, Xian, P R China Nuffield Department of Surgical Sciences, Oxford University, Oxford, United Kingdom Oxford Breast Unit, Oxford Radcliffe Hospitals NHS Trust, John Radcliffe Hospital, Headley Way, Oxford, United Kingdom
    Cancer Res 74:5711-22. 2014

Collaborators

  • Ruth J Muschel
  • Danmei Xu
  • Chad M McKee
  • Peng H Tan
  • Yunhong Cao
  • Wafik S El-Deiry
  • Jianfeng Zhou
  • Jing He
  • Xiangke Xin
  • Joshua E Allen
  • Liang Huang
  • Chunrui Li
  • John Z Xue
  • Yuan Chen
  • Helen E J Tyrrell
  • Michael J Greenall
  • Dipender Gill
  • Kenneth Walsh
  • Jianchao Quan
  • Liquan Gao
  • Lena Rai
  • Ashok I Handa
  • Shao An Xue
  • Gareth Plant
  • Benedikt M Kessler

Detail Information

Publications5

  1. pmc Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9
    Yunchuan Ding
    Transplantation Research Immunology Group, Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Diabetes 58:1797-806. 2009
    ..Mesenchymal stem cells (MSCs) are known to be capable of suppressing immune responses, but the molecular mechanisms involved and the therapeutic potential of MSCs remain to be clarified...
  2. pmc Mesenchymal stem-cell immunosuppressive capabilities: therapeutic implications in islet transplantation
    Yunchuan Ding
    Transplantation Research Immunology Group, Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    Transplantation 89:270-3. 2010
    ..This review will discuss the impacts of MSCs on transplant immunity and focus on the potential role of MSCs in protecting islet grafts from both rejection and autoimmune attack...
  3. pmc Matrix metalloproteinase-9 regulates tumor cell invasion through cleavage of protease nexin-1
    Danmei Xu
    Gray Institute of Radiation Oncology and Biology, University of Oxford, Oxford, UK
    Cancer Res 70:6988-98. 2010
    ..This study shows a novel molecular pathway in which MMP-9 regulates uPA activity and tumor cell invasion through cleavage of PN-1...
  4. pmc Protease nexin 1 induces apoptosis of prostate tumor cells through inhibition of X-chromosome-linked inhibitor of apoptosis protein
    Chad M McKee
    Gray Institute of Radiation Oncology and Biology, Medical Science Division, University of Oxford, Oxford, United Kingdom
    Oncotarget 6:3784-96. 2015
    ....
  5. pmc Adiponectin receptor signaling on dendritic cells blunts antitumor immunity
    Peng H Tan
    Genetic Engineering Laboratory, College of Biotechnology, Xi An University, Xian, P R China Nuffield Department of Surgical Sciences, Oxford University, Oxford, United Kingdom Oxford Breast Unit, Oxford Radcliffe Hospitals NHS Trust, John Radcliffe Hospital, Headley Way, Oxford, United Kingdom
    Cancer Res 74:5711-22. 2014
    ..Furthermore, by defining a critical role for adiponectin signaling in this process, our work suggests new and broadly applicable strategies for immunometabolic therapy in patients with cancer...