Dina Dikovskaya

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. doi Microtubule assembly by the Apc protein is regulated by importin-beta--RanGTP
    Dina Dikovskaya
    Division of Cell and Developmental Biology, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK
    J Cell Sci 123:736-46. 2010
  2. pmc Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis
    Dina Dikovskaya
    Division of Cell and Developmental Biology, University of Dundee, Dundee DD1 5EH, Scotland, UK
    J Cell Biol 176:183-95. 2007
  3. pmc The adenomatous polyposis coli protein is required for the formation of robust spindles formed in CSF Xenopus extracts
    Dina Dikovskaya
    Division of Cell and Developmental Biology, University of Dundee, WTB MSI Complex, Dundee DD1 5EH, Scotland
    Mol Biol Cell 15:2978-91. 2004
  4. pmc Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability
    Karin Kroboth
    Division of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom
    Mol Biol Cell 18:910-8. 2007
  5. ncbi Dephosphorylation of the inhibitory phosphorylation site S287 in Xenopus Cdc25C by protein phosphatase-2A is inhibited by 14-3-3 binding
    James R A Hutchins
    Biomedical Research Centre, Level 5, Ninewells Hospital and Medical School, University of Dundee, UK
    FEBS Lett 528:267-71. 2002
  6. ncbi Open microscopy environment and findspots: integrating image informatics with quantitative multidimensional image analysis
    David A Schiffmann
    University of Dundee, Dundee, Scotland, UK
    Biotechniques 41:199-208. 2006

Collaborators

Detail Information

Publications6

  1. doi Microtubule assembly by the Apc protein is regulated by importin-beta--RanGTP
    Dina Dikovskaya
    Division of Cell and Developmental Biology, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK
    J Cell Sci 123:736-46. 2010
    ..Thus, importin-beta binds to Apc and negatively regulates the MT-assembly and spindle-promoting activity of Apc in a Ran-regulatable manner...
  2. pmc Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis
    Dina Dikovskaya
    Division of Cell and Developmental Biology, University of Dundee, Dundee DD1 5EH, Scotland, UK
    J Cell Biol 176:183-95. 2007
    ..We suggest that these defects amplify each other to increase the incidence of tetra- and polyploidy in early stages of tumorigenesis...
  3. pmc The adenomatous polyposis coli protein is required for the formation of robust spindles formed in CSF Xenopus extracts
    Dina Dikovskaya
    Division of Cell and Developmental Biology, University of Dundee, WTB MSI Complex, Dundee DD1 5EH, Scotland
    Mol Biol Cell 15:2978-91. 2004
    ..We propose that lack of microtubule binding in cancer-associated mutations of APC may contribute to defects in the assembly of mitotic spindles and lead to missegregation of chromosomes...
  4. pmc Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability
    Karin Kroboth
    Division of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom
    Mol Biol Cell 18:910-8. 2007
    ..These data demonstrate that cell migration and microtubule stability are linked to APC status, thereby revealing a weakness in APC-deficient cells with potential therapeutic implications...
  5. ncbi Dephosphorylation of the inhibitory phosphorylation site S287 in Xenopus Cdc25C by protein phosphatase-2A is inhibited by 14-3-3 binding
    James R A Hutchins
    Biomedical Research Centre, Level 5, Ninewells Hospital and Medical School, University of Dundee, UK
    FEBS Lett 528:267-71. 2002
    ..The rate of dephosphorylation of S287 is not increased in mitotic extracts, indicating that the phosphorylation status of the site is likely to be controlled through modulation of kinases or 14-3-3 binding activity...
  6. ncbi Open microscopy environment and findspots: integrating image informatics with quantitative multidimensional image analysis
    David A Schiffmann
    University of Dundee, Dundee, Scotland, UK
    Biotechniques 41:199-208. 2006
    ....