Research Topics
Species | R DicksonSummaryAffiliation: University of Liverpool Country: UK Publications
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Detail Information
Publications
Erlotinib monotherapy for the maintenance treatment of non-small cell lung cancer after previous platinum-containing chemotherapy: a NICE single technology appraisalRumona Dickson
Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK
Pharmacoeconomics 29:1051-62. 2011..All values were above NICE's perceived willingness-to-pay threshold. After the second Appraisal Committee meeting, the Committee did not recommend the use of erlotinib in this patient population...
Putting evidence into practiceR Dickson
International Health Division, Liverpool School of Tropical Medicine, England
World Health Forum 19:311-4. 1998....
Effects of treatment for intestinal helminth infection on growth and cognitive performance in children: systematic review of randomised trialsR Dickson
International Health Division, Liverpool School of Tropical Medicine, Liverpool L3 5QA
BMJ 320:1697-701. 2000..To summarise the effects of anthelmintic drug treatment on growth and cognitive performance in children...
Pemetrexed for the first-line treatment of locally advanced or metastatic non-small cell lung cancerN Fleeman
Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK
Health Technol Assess 14:47-53. 2010....
Lapatinib and trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone receptor-positive breast cancer which over-expresses human epidermal growth factor 2 (HER2): a systematic review and economic analysisN Fleeman
Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK
Health Technol Assess 15:1-93, iii-iv. 2011..Hormone receptor status and human epidermal growth factor 2 (HER2) status are two predictive factors that are taken into consideration when estimating the prognosis of patients with breast cancer...
Rituximab for the treatment of relapsed or refractory stage III or IV follicular non-Hodgkin's lymphomaA Boland
Liverpool Reviews and Implementation Group, Sherrington Buildings, University of Liverpool, Liverpool, UK
Health Technol Assess 13:41-8. 2009..Rituximab monotherapy is also an option for people with relapsed or refractory disease when all alternative treatment options have been exhausted...
Cytochrome P450 testing for prescribing antipsychotics in adults with schizophrenia: systematic review and meta-analysesN Fleeman
Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK
Pharmacogenomics J 11:1-14. 2011..Further research is required to improve the evidence base and to generate data on clinical validity and clinical utility...
The clinical effectiveness and cost-effectiveness of genotyping for CYP2D6 for the management of women with breast cancer treated with tamoxifen: a systematic reviewN Fleeman
Liverpool Reviews and Implementation Group LRiG, University of Liverpool, Liverpool, UK
Health Technol Assess 15:1-102. 2011....
Rituximab for the treatment of rheumatoid arthritisA Bagust
Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK
Health Technol Assess 13:23-9. 2009....
Gefitinib for the first-line treatment of locally advanced or metastatic non-small cell lung cancerT Brown
Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK
Health Technol Assess 14:71-9. 2010....
Pemetrexed for the maintenance treatment of locally advanced or metastatic non-small cell lung cancerJ Greenhalgh
Liverpool Reviews and Implementation Group, University of Liverpool, Whelan Building, The Quadrangle, Brownlow Hill, Liverpool, UK
Health Technol Assess 14:33-9. 2010....
Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events (review of Technology Appraisal No. 90): a systematic review and economic analysisJ Greenhalgh
Liverpool Reviews and Implementation Group LRiG, University of Liverpool, Liverpool, UK
Health Technol Assess 15:1-178. 2011..The primary objective in the treatment of all patients with a history of occlusive vascular events and peripheral arterial disease is to prevent the occurrence of new occlusive vascular events...
The clinical effectiveness and cost-effectiveness of primary stroke prevention in children with sickle cell disease: a systematic review and economic evaluationM G Cherry
Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK
Health Technol Assess 16:1-129. 2012..No reviews have yet assessed the clinical effectiveness and cost effectiveness of primary stroke prevention strategies in children with SCD identified to be at high risk of stroke using TCD ultrasonography...
Prasugrel for the treatment of acute coronary artery syndromes with percutaneous coronary interventionJ Greenhalgh
Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK
Health Technol Assess 14:31-8. 2010..At the time of writing, the guidance/has not yet been published by NICE...
Systematic review and cost-effectiveness evaluation of 'pill-in-the-pocket' strategy for paroxysmal atrial fibrillation compared to episodic in-hospital treatment or continuous antiarrhythmic drug therapyC Martin Saborido
Liverpool Reviews and Implementation Group LRiG, Liverpool, UK
Health Technol Assess 14:iii-iv, 1-75. 2010..9 to 1.1), and reported prevalence rates show wide variations depending on age and country. Conventional treatment strategies for PAF focus on the suppression of paroxysms of AF and return to normal sinus rhythm...
Clinical effectiveness of first-line chemoradiation for adult patients with locally advanced non-small cell lung cancer: a systematic reviewT Brown
Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK
Health Technol Assess 17:1-99. 2013..g. stage IIIA) are different from those with advanced disease, who are suitable for palliative treatment only, and therefore the results should be reported separately...
A systematic review of the clinical effectiveness and cost-effectiveness of Pharmalgen® for the treatment of bee and wasp venom allergyJ Hockenhull
Liverpool Reviews and Implementation Group, Liverpool, UK
Health Technol Assess 16:III-IV, 1-110. 2012..Pharmalgen® products (ALK Abelló) have had UK marketing authorisation for VIT (as well as diagnosis) of allergy to bee venom (using Pharmalgen Bee Venom) and wasp venom (using Pharmalgen Wasp Venom) since March 1995...
The clinical effectiveness and cost-effectiveness of testing for cytochrome P450 polymorphisms in patients with schizophrenia treated with antipsychotics: a systematic review and economic evaluationN Fleeman
Liverpool Reviews and Implementation Group, University of Liverpool, UK
Health Technol Assess 14:1-157, iii. 2010....
Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional haemosiderosis) in patients suffering with chronic anaemia: a systematic review and economic evaluationC McLeod
Liverpool Reviews and Implementation Group, University of Liverpool, UK
Health Technol Assess 13:iii-iv, ix-xi, 1-121. 2009....
Best supportive care in lung cancer trials is inadequately described: a systematic reviewB Jack
Faculty of Health, Edge Hill University, Liverpool, and Marie Curie Palliative Care Institute, Liverpool, UK
Eur J Cancer Care (Engl) 19:293-301. 2010..Inadequate definitions mean that all direct and indirect comparisons in trials comparing active treatments with best supportive care must be interpreted with caution...
A systematic review of prevention and intervention strategies for populations at high risk of engaging in violent behaviour: update 2002-8J C Hockenhull
Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK
Health Technol Assess 16:1-152. 2012..This review was designed to examine the effectiveness of these interventions when they are developed in mental health and criminal justice populations...
The effects of biofeedback for the treatment of essential hypertension: a systematic reviewJ Greenhalgh
Liverpool Reviews and Implementation Group, University of Liverpool, Liverpool, UK
Health Technol Assess 13:1-104. 2009..To assess the evidence for the long-term effectiveness of biofeedback for the treatment of essential hypertension in adults and to model any clinical benefits...
Erlotinib for the treatment of relapsed non-small cell lung cancerC McLeod
Liverpool Reviews and Implementation Group LRiG, Room B05, Whelan Building, The Quadrangle, Brownlow Hill, University of Liverpool, Liverpool, UK
Health Technol Assess 13:41-7. 2009..The guidance issued by NICE in February 2007 as a result of the STA states that erlotinib is not recommended for the treatment of locally advanced or metastatic NSCLC...
Comparative efficacy of thrombolytics in acute myocardial infarction: a systematic reviewY Dundar
Department of Pharmacology and Therapeutics, University of Liverpool, UK
QJM 96:103-13. 2003....
Superiority and equivalence in thrombolytic drugs: an interpretationT Walley
Department of Pharmacology and Therapeutics, University of Liverpool, UK
QJM 96:155-60. 2003
Early thrombolysis for the treatment of acute myocardial infarction: a systematic review and economic evaluationA Boland
Liverpool Reviews and Implementation Group, New Medical School, Liverpool, UK
Health Technol Assess 7:1-136. 2003
Coronary artery stents: a rapid systematic review and economic evaluationR Hill
Liverpool Reviews and Implementation Group, Liverpool, UK
Health Technol Assess 8:iii-iv, 1-242. 2004....
Molecular cloning and functional characterization of murine sphingosine kinaseT Kohama
Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, Washington, DC 20007, USA
J Biol Chem 273:23722-8. 1998..Our data suggest that sphingosine kinase is a prototypical member of a new class of lipid kinases. Cloning of sphingosine kinase is an important step in corroborating the intracellular role of SPP as a second messenger...
Cloning, expression, and purification of a functional nonacetylated mammalian mitochondrial chaperonin 10R Dickson
Molecular Biology Division, E I duPont de Nemours and Company, Wilmington, Delaware 19880 0402
J Biol Chem 269:26858-64. 1994..More important, like the authentic protein purified from mitochondria, the recombinant mitochondrial chaperonin 10, but not groES, is functionally compatible with the heptameric chaperonin 60 of mammalian mitochondria...
