A M Dickinson

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. ncbi request reprint Risk assessment in haematopoietic stem cell transplantation: pre-transplant patient and donor factors: non-HLA genetics
    Anne M Dickinson
    School of Clinical and Laboratory Sciences, Haematological Sciences, Newcastle University, The Medical School, Newcastle upon Tyne NE2 4HH, UK
    Best Pract Res Clin Haematol 20:189-207. 2007
  2. ncbi request reprint Beyond the HLA typing age: genetic polymorphisms predicting transplant outcome
    Anne M Dickinson
    School of Clinical and Laboratory Sciences, University of Newcastle upon Tyne, The Medical School, Newcastle upon Tyne NE2 4HH, UK
    Blood Rev 19:333-40. 2005
  3. ncbi request reprint Haemopoietic stem-cell transplantation: improving immune reconstitution, avoiding graft-versus-host disease
    Anne Dickinson
    University Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne NEI 4LP, UK
    Lancet 360:98-9. 2002
  4. pmc Impact of genomic risk factors on outcome after hematopoietic stem cell transplantation for patients with chronic myeloid leukemia
    Anne M Dickinson
    Haematological Sciences, Institute of Cellular Medicine, Newcastle University, UK
    Haematologica 95:922-7. 2010
  5. ncbi request reprint Haematopoietic stem cell transplantation: can our genes predict clinical outcome?
    Anne M Dickinson
    School of Clinical and Laboratory Sciences, Institute of Cellular Medicine, Newcastle University Medical School, Newcastle upon Tyne, UK
    Expert Rev Mol Med 9:1-19. 2007
  6. ncbi request reprint Predicting outcome in hematological stem cell transplantation
    Anne M Dickinson
    University Department Haematology, Tyneside Leukemia Research Laboratory, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, UK
    Arch Immunol Ther Exp (Warsz) 50:371-8. 2002
  7. doi request reprint Polymorphisms of cytokine and innate immunity genes and GVHD
    A M Dickinson
    School of Clinical and Laboratory Sciences, Institute of Cellular Medicine, Newcastle University Medical School, Newcastle upon Tyne, UK
    Best Pract Res Clin Haematol 21:149-64. 2008
  8. doi request reprint Non-HLA genetics and predicting outcome in HSCT
    A M Dickinson
    School of Clinical and Laboratory Sciences, The Medical School, Newcastle University, Newcastle upon Tyne, UK
    Int J Immunogenet 35:375-80. 2008
  9. ncbi request reprint Genetic polymorphisms predicting the outcome of bone marrow transplants
    Anne M Dickinson
    Haematological Sciences, School of Clinical and Laboratory Medicine, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH, UK
    Br J Haematol 127:479-90. 2004
  10. ncbi request reprint Vitamin D receptor gene polymorphism associates with graft-versus-host disease and survival in HLA-matched sibling allogeneic bone marrow transplantation
    P G Middleton
    University Department of Haematology, The Medical School, Newcastle upon Tyne, UK
    Bone Marrow Transplant 30:223-8. 2002

Detail Information

Publications48

  1. ncbi request reprint Risk assessment in haematopoietic stem cell transplantation: pre-transplant patient and donor factors: non-HLA genetics
    Anne M Dickinson
    School of Clinical and Laboratory Sciences, Haematological Sciences, Newcastle University, The Medical School, Newcastle upon Tyne NE2 4HH, UK
    Best Pract Res Clin Haematol 20:189-207. 2007
    ..Future directions - including the role of pharmacogenomics, use of the research results for individualized medicine, and interpretation of data - will also be discussed...
  2. ncbi request reprint Beyond the HLA typing age: genetic polymorphisms predicting transplant outcome
    Anne M Dickinson
    School of Clinical and Laboratory Sciences, University of Newcastle upon Tyne, The Medical School, Newcastle upon Tyne NE2 4HH, UK
    Blood Rev 19:333-40. 2005
    ..This review will summarise the latest research concerning this area of predicting HSCT outcome and indicate the potential clinical use of the results...
  3. ncbi request reprint Haemopoietic stem-cell transplantation: improving immune reconstitution, avoiding graft-versus-host disease
    Anne Dickinson
    University Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne NEI 4LP, UK
    Lancet 360:98-9. 2002
  4. pmc Impact of genomic risk factors on outcome after hematopoietic stem cell transplantation for patients with chronic myeloid leukemia
    Anne M Dickinson
    Haematological Sciences, Institute of Cellular Medicine, Newcastle University, UK
    Haematologica 95:922-7. 2010
    ..Non-HLA gene polymorphisms have been shown to influence outcome after allogeneic hematopoietic stem cell transplantation. Results were derived from heterogeneous, small populations and their value remains a matter of debate...
  5. ncbi request reprint Haematopoietic stem cell transplantation: can our genes predict clinical outcome?
    Anne M Dickinson
    School of Clinical and Laboratory Sciences, Institute of Cellular Medicine, Newcastle University Medical School, Newcastle upon Tyne, UK
    Expert Rev Mol Med 9:1-19. 2007
    ..The clinical relevance and interpretation of non-HLA genetics, and how these could be used alongside clinical risk factors in HSCT, are also discussed...
  6. ncbi request reprint Predicting outcome in hematological stem cell transplantation
    Anne M Dickinson
    University Department Haematology, Tyneside Leukemia Research Laboratory, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, UK
    Arch Immunol Ther Exp (Warsz) 50:371-8. 2002
    ..By the comparative use of an in vitro human skin explant model, initial results suggest that certain cytokine gene polymorphisms may be associated with more severe disease...
  7. doi request reprint Polymorphisms of cytokine and innate immunity genes and GVHD
    A M Dickinson
    School of Clinical and Laboratory Sciences, Institute of Cellular Medicine, Newcastle University Medical School, Newcastle upon Tyne, UK
    Best Pract Res Clin Haematol 21:149-64. 2008
    ..The potential of these non-HLA genetics to aid in predicting GVHD and post-transplant survival and the relevance of this information to the clinic are reviewed...
  8. doi request reprint Non-HLA genetics and predicting outcome in HSCT
    A M Dickinson
    School of Clinical and Laboratory Sciences, The Medical School, Newcastle University, Newcastle upon Tyne, UK
    Int J Immunogenet 35:375-80. 2008
    ..This review summarises some of the studies and relates the results to their potential for improving HSCT outcome by predicting transplant-related mortality and GvHD...
  9. ncbi request reprint Genetic polymorphisms predicting the outcome of bone marrow transplants
    Anne M Dickinson
    Haematological Sciences, School of Clinical and Laboratory Medicine, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH, UK
    Br J Haematol 127:479-90. 2004
    ..This review gives an overall perspective of the current field of non-HLA genetics with regard to HSCT outcome, clinical relevance and potential application of the results to clinical management of HSCT...
  10. ncbi request reprint Vitamin D receptor gene polymorphism associates with graft-versus-host disease and survival in HLA-matched sibling allogeneic bone marrow transplantation
    P G Middleton
    University Department of Haematology, The Medical School, Newcastle upon Tyne, UK
    Bone Marrow Transplant 30:223-8. 2002
    ..Analysis of VDR genotype in prospective BMT donors may identify individuals who have greater transplant-related mortality, and also allow appropriately restricted use of increased immunosuppressive prophylaxis...
  11. ncbi request reprint Oestrogen receptor alpha gene polymorphism associates with occurrence of graft-versus-host disease and reduced survival in HLA-matched sib-allo BMT
    P G Middleton
    Department of Haematology, School of Clinical Laboratory Sciences, The Medical School, Framlington Place, Newcastle upon Tyne, UK
    Bone Marrow Transplant 32:41-7. 2003
    ....
  12. ncbi request reprint Interferon-gamma and interleukin-6 gene polymorphisms associate with graft-versus-host disease in HLA-matched sibling bone marrow transplantation
    J Cavet
    University Department of Haematology, School of Clinical and Laboratory Sciences, The Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom
    Blood 98:1594-600. 2001
    ..Assessment of cytokine genotype may potentially allow more accurate prediction of GVHD and appropriate adjustment of GVHD prophylaxis, as well as indicating novel areas for future studies of GVHD pathogenesis...
  13. ncbi request reprint Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants
    P G Middleton
    Leukaemia Research Fund LRF Laboratory, Catherine Cookson Building, The Medical School, Framlington Place, Newcastle upon Tyne, UK
    Blood 92:3943-8. 1998
    ....
  14. ncbi request reprint GvHD risk assessment in hematopoietic stem cell transplantation: role of cytokine gene polymorphisms and an in vitro human skin explant model
    A M Dickinson
    University Department of Haematology, Tyneside Leukaemia Research Laboratory, Royal Victoria Infirmary, Newcastle-upon-Tyne, United Kingdom
    Hum Immunol 62:1266-76. 2001
    ..By the comparative use of an in vitro human skin explant model, initial results suggest that certain polymorphisms may be associated with more severe disease...
  15. ncbi request reprint Heat shock protein 70: correlation of expression with degree of graft-versus-host response and clinical graft-versus-host disease
    M Jarvis
    University Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Transplantation 76:849-53. 2003
    ..Their proposed role in peptide binding and antigen presentation could suggest a potential role in the alloreactive process that leads to graft-versus-host disease (GVHD) after bone marrow transplantation...
  16. ncbi request reprint The levels of TNF alpha, IL4 and IL10 production by T-cells in B-cell chronic lymphocytic leukaemia (B-CLL)
    T Mainou-Fowler
    Department of Haematology, School of Clinical and Laboratory Sciences, Royal Victoria Infirmary, Queen Victoria Road, New Castle upon Tyne, NE1 4 LP, UK
    Leuk Res 25:157-63. 2001
    ..The differences observed with some B-CLL cases in the production of TNF alpha, IL4 and IL10 by peripheral blood T-cells may suggest survival mechanisms for the leukaemic cells in these patients...
  17. ncbi request reprint Expression and production of interleukin 4 in B-cell chronic lymphocytic leukaemia
    T Mainou-Fowler
    University Department of Haematology, School of Clinical and Laboratory Sciences, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Leuk Lymphoma 42:689-98. 2001
    ..49 and r=0.76, respectively). The significant differences observed in the production of IL4 by B-CLL B- and T-lymphocytes may suggest a paracrine function of IL4 in B-CLL...
  18. pmc Environmental factors and not genotype influence the plasma level of interleukin-1 receptor antagonist in normal individuals
    H Cullup
    Haematological Sciences, School of Clinical Laboratory Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Clin Exp Immunol 137:351-8. 2004
    ..Genotypic associations of IL-1 gene family polymorphisms with disease features may reflect characteristics of stressed rather than normal control circuits for cytokine production...
  19. ncbi request reprint Interleukin-10 modulation of alloreactivity and graft-versus-host reactions
    Xiao Nong Wang
    Department of Haematology, School of Clinical and Laboratory Sciences, University of Newcastle, Newcastle upon Tyne, United Kingdom
    Transplantation 74:772-8. 2002
    ..This study aims to demonstrate, for the first time, whether the addition of exogenous IL-10 can reduce the severity of graft-versus-host reactions (GvHR) in humans...
  20. ncbi request reprint Skin explant model of human graft-versus-host disease: prediction of clinical outcome and correlation with biological risk factors
    Xiao Nong Wang
    Haematological Sciences, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom
    Biol Blood Marrow Transplant 12:152-9. 2006
    ..The model has also the potential to aid the development of novel prophylaxis and treatment for GVHD...
  21. ncbi request reprint Non-HLA immunogenetics in hematopoietic stem cell transplantation
    Anne M Dickinson
    Haematological Sciences, School of Clinical and Laboratory Sciences, The Medical School, Framlington Place, Newcastle upon Tyne, UK
    Curr Opin Immunol 17:517-25. 2005
    ....
  22. ncbi request reprint Donor interleukin 1 receptor antagonist genotype associated with acute graft-versus-host disease in human leucocyte antigen-matched sibling allogeneic transplants
    H Cullup
    The Leukaemia Research Fund LRF Laboratory, Cookson Building, The Medical School, Newcastle upon Tyne, UK
    Br J Haematol 113:807-13. 2001
    ....
  23. ncbi request reprint Biobanks and registries for HSCT research: potential for future individualized medicine
    A M Dickinson
    Haematological Sciences, School of Clinical and Laboratory Sciences, The Medical School, Newcastle upon Tyne, UK
    Int J Immunogenet 33:153-4. 2006
  24. ncbi request reprint A comparison of CFU-GM, BFU-E and endothelial progenitor cells using ex vivo expansion of selected cord blood CD133(+) and CD34(+) cells
    X Lu
    Haematological Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, NE2 4HH, UK
    Cytotherapy 9:292-300. 2007
    ..The present study compared colony formation and endothelial cell differentiation of these two cell types from umbilical cord blood (UCB)...
  25. ncbi request reprint Tumour necrosis factor receptor type II 196M/R genotype correlates with circulating soluble receptor levels in normal subjects and with graft-versus-host disease after sibling allogeneic bone marrow transplantation
    Gail L Stark
    Department of Haematology, Royal Victoria Infirmary, University of Newcastle, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, United Kingdom
    Transplantation 76:1742-9. 2003
    ....
  26. doi request reprint Regulatory T-cell suppression of CD8+ T-cell-mediated graft-versus-host reaction requires their presence during priming
    Xiao Nong Wang
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom
    Transplantation 88:188-97. 2009
    ..It is also unknown whether Treg modulation of GVH histopathologic damage relies on their presence during effector T-cell priming, or whether allogeneic Treg are safe to use clinically...
  27. ncbi request reprint Quantification improves the prognostic value of CD38 expression in B-cell chronic lymphocytic leukaemia
    Tryfonia Mainou-Fowler
    University Department of Haematology, School of Clinical and Laboratory Sciences, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Haematol 118:755-61. 2002
    ..However, quantification of CD38 is superior to the percentage positivity and should be used clinically in conjunction with other variables of predictive value to identify B-CLL patients that are likely to progress...
  28. ncbi request reprint The 6th annual meeting of the UK Cord Blood and Adult Stem Cell Group
    Xiao N Wang
    Newcastle University Medical School, Department of Haematology, School of Clinical and Laboratory Sciences, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK
    Expert Opin Biol Ther 6:417-21. 2006
    ..The meeting was introduced and chaired by Professor Anne Dickinson, University of Newcastle upon Tyne, UK...
  29. pmc The fate of human Langerhans cells in hematopoietic stem cell transplantation
    Matthew P Collin
    Haematological Sciences, University of Newcastle, Newcastle upon Tyne NE2 4HH, England, UK
    J Exp Med 203:27-33. 2006
    ..At 100 d, all transplants achieve at least 90% LC donor chimerism and over half achieve 100%. Complete donor chimerism is associated with prior acute cutaneous GVHD, suggesting a role for allogeneic T cells in promoting LC engraftment...
  30. ncbi request reprint Intracellular cytokine profiles by peripheral blood CD3+ T-cells in patients with classical Hodgkin lymphoma
    Tryfonia Mainou-Fowler
    University Department of Haematology, School of Clinical and Laboratory Sciences, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK
    Leuk Lymphoma 44:1325-31. 2003
    ..In conclusion, there is reduced intracellular IL2, TNFalpha and IFNgamma and increased cytoplasmic IL4 production by activated PB T-cells in patients with HL. The CD3+CD8+ sub-population is responsible for the increased levels of IL4...
  31. ncbi request reprint In vitro depletion of tissue-derived dendritic cells by CMRF-44 antibody and alemtuzumab: implications for the control of Graft-versus-host disease
    Matthew P Collin
    Hematological Sciences, University of Newcastle, Newcastle upon Tyne, NE2 4HH, UK
    Transplantation 79:722-5. 2005
    ..These results highlight the potential of new therapeutic antibodies active against tissue DC to control graft-versus-host reactions...
  32. ncbi request reprint Polymorphisms of interleukin-1alpha constitute independent risk factors for chronic graft-versus-host disease after allogeneic bone marrow transplantation
    Hannah Cullup
    Haematological Sciences, School of Clinical Laboratory Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Br J Haematol 122:778-87. 2003
    ..Both loci could therefore function as independent disease association markers. The polymorphisms of the IL-1alpha gene could be used to predict chronic GVHD in HLA-matched sibling transplants alongside clinical risk factors...
  33. ncbi request reprint In situ dissection of the graft-versus-host activities of cytotoxic T cells specific for minor histocompatibility antigens
    Anne M Dickinson
    University Department of Haematology, Royal Victoria Infirmary, University of Newcastle, Newcastle upon Tyne, UK
    Nat Med 8:410-4. 2002
    ..These results provide the first in situ dissection of GvH effects by mHag-specific CTLs and show that ubiquitously expressed mHags are the prime targets of GvH disease...
  34. pmc The detection of apoptosis in a human in vitro skin explant assay for graft versus host reactions
    M Jarvis
    Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
    J Clin Pathol 55:127-32. 2002
    ..The basis of this investigation was to correlate keratinocyte apoptosis with (1) the severity of graft versus host reactions (GVHR) in vitro and (2) the clinical grade (0--III) of GVHD...
  35. doi request reprint Mesenchymal stem cells from CD34(-) human umbilical cord blood
    X Lu
    Haematological Sciences, School of Clinical and Laboratory Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK
    Transfus Med 20:178-84. 2010
    ..Our results showed that UCB contained MSCs which are only resident in the CD34(-) fraction. The MSCs could be induced to differentiate into at least three lineage cell types, adipocytes, osteoblasts and chondrocytes...
  36. doi request reprint Impact of psoralen/UVA-treatment on survival, activation, and immunostimulatory capacity of monocyte-derived dendritic cells
    Udo Holtick
    Haematological Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    Transplantation 85:757-66. 2008
    ..It has been suggested that dendritic cells (DCs) are more resistant to ECP-induced apoptosis and might be directly modulated by ECP. We tested this hypothesis using in vitro Psoralen/UVA (PUVA) treatment as an in vitro model of ECP...
  37. ncbi request reprint Adult human fibroblasts are potent immunoregulatory cells and functionally equivalent to mesenchymal stem cells
    Muzlifah A Haniffa
    Hematological Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK
    J Immunol 179:1595-604. 2007
    ..These results suggest that immunosuppression is a general property of stromal cells and that dermal Fb may provide an alternative and accessible source of cellular therapy...
  38. ncbi request reprint Gamma-linolenic acid induces apoptosis in B-chronic lymphocytic leukaemia cells in vitro
    T Mainou-Fowler
    University Department of Haematology, School of Clinical, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
    Leuk Lymphoma 40:393-403. 2001
    ..These results demonstrate that GLA induces apoptosis in B-CLL B- and T-cells cells in vitro and that they are more susceptible to GLA-induced apoptosis than normal peripheral blood B- and T-cells...
  39. ncbi request reprint Smooth muscle alpha-actin expression in endothelial cells derived from CD34+ human cord blood cells
    Xiaomei Lu
    University Department of Surgical and Reproductive Sciences, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, United Kingdom
    Stem Cells Dev 13:521-7. 2004
    ..Human fetal cord blood contains a population of cells that may differentiate toward both an endothelial and a smooth muscle phenotype in culture...
  40. ncbi request reprint Donor CD31 genotype impacts on transplant complications after human leukocyte antigen-matched sibling allogeneic bone marrow transplantation
    Gary Cavanagh
    Department of Histocompatibility and Immunogenetics, National Blood Service, Newcastle, Holland Drive, Barrack Road, Newcastle upon Tyne, United Kingdom
    Transplantation 79:602-5. 2005
    ..Assessment for CD31 gene status may be of value in pretransplant assessment of bone marrow transplant recipients and donors for prediction of likely transplant-related complications...
  41. ncbi request reprint Towards functional transplant donor matching by measurement of granzyme A and granzyme B production levels
    Brigitte Kircher
    Laboratory for Tumor and Immunobiology, Department of Hematology and Oncology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    J Immunol Methods 293:51-9. 2004
    ..This novel and simple method may be used for functional selection of unrelated stem cell donors and for the identification of patients who are at risk for acute GvHD grades II-IV...
  42. ncbi request reprint Recipient cytokine genotypes for TNF-alpha and IL-10 and the minor histocompatibility antigens HY and CD31 codon 125 are not associated with occurrence or severity of acute GVHD in unrelated cord blood transplantation: a retrospective analysis
    Gesine Kogler
    José Carreras Eurocord Netcord Bank Germany, Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University, Moorenstrasse 5, Bldg 14 80, 40225 Dusseldorf, Germany
    Transplantation 74:1167-75. 2002
    ....
  43. doi request reprint Correlation of Hsp70-1 and Hsp70-2 gene expression with the degree of graft-versus-host reaction in a rat skin explant model
    Peter Novota
    Department of Cellular and Molecular Immunology, University of Gottingen, Gottingen, Germany
    Transplantation 85:1809-16. 2008
    ..New molecular markers of GVHR might help to further increase the predictive value of the assay...
  44. ncbi request reprint Prognostic significance of NOD2/CARD15 variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on long-term outcome is confirmed in 2 independent cohorts and may be modulated by the type of gastrointestinal decontamination
    Ernst Holler
    Department of Haematology Oncology, Medical Centre, University of Regensburg, Franz Josef Strauss Allee 11, 93042 Regensburg, Germany
    Blood 107:4189-93. 2006
    ..Our data further support an interaction between gastrointestinal defense mechanisms, activation of the innate immune system, and specific transplant-related complications...
  45. ncbi request reprint Recipient NOD2/CARD15 variants: a novel independent risk factor for the development of bronchiolitis obliterans after allogeneic stem cell transplantation
    Gerhard C Hildebrandt
    Department of Hematology and Oncology, University of Regensburg Medical School, Regensburg, Germany
    Biol Blood Marrow Transplant 14:67-74. 2008
    ..2% (P = .04). Multivariate analysis proved recipient but not donor NOD2/CARD15 variants to be a novel independent risk factor for BO development, and NOD2/CARD15 typing may help identify patients at increased risk for BO...
  46. ncbi request reprint Long-term immune reconstitution after anti-CD52-treated or anti-CD34-treated hematopoietic stem cell transplantation for severe T-lymphocyte immunodeficiency
    Mary A Slatter
    Department of Paediatric Immunology, Newcastle upon Tyne Hospitals Foundation Trust, Newcastle upon Tyne, United Kingdom
    J Allergy Clin Immunol 121:361-7. 2008
    ..T cell-depleted haploidentical transplantations are successful if there is no HLA-identical donor. Methods to remove T lymphocytes include addition of anti-CD52 antibodies and CD34(+) HSC selection...
  47. ncbi request reprint Impact of mismatching CD1a, a dimorphic antigen-presenting molecule, on graft-versus-host disease after hematopoietic stem cell transplantation
    Eleanor M Lanning
    Haematological Sciences, Medical School, University of Newcastle, Newcastle upon Tyne, United Kingdom
    Transplantation 82:1374-6. 2006
    ..This suggests that, unlike conventional class I molecules, CD1a does not function as a transplantation antigen and does not require matching in hematopoietic stem cell transplantation...
  48. ncbi request reprint Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosis
    Gordon Strathdee
    Centre for Oncology and Applied Pharmacology, Cancer Research UK
    Clin Cancer Res 13:5048-55. 2007
    ..We aimed to study the role of DNA methylation as an inducer of HOX gene silencing in leukemia...