Mickael Desvaux

Summary

Affiliation: University of Birmingham
Country: UK

Publications

  1. ncbi request reprint The general secretory pathway: a general misnomer?
    Mickael Desvaux
    Institute for Biomedical Research, The University of Birmingham The Medical School, Division of Immunity and Infection, Bacterial Pathogenesis and Genomics Unit, Vincent Drive, Edgbaston, Birmingham, UK B15 2TT
    Trends Microbiol 12:306-9. 2004
  2. ncbi request reprint Genomic analysis of the protein secretion systems in Clostridium acetobutylicum ATCC 824
    Mickael Desvaux
    The Institute for Biomedical Research IBR, The University of Birmingham The Medical School, Division of Immunity and Infection, Bacterial Pathogenesis and Genomics Unit, Edgbaston, Birmingham B15 2TT, UK
    Biochim Biophys Acta 1745:223-53. 2005
  3. ncbi request reprint Clostridium cellulolyticum: model organism of mesophilic cellulolytic clostridia
    Mickael Desvaux
    Institute for Biomedical Research, The University of Birmingham The Medical School, Edgbaston, UK
    FEMS Microbiol Rev 29:741-64. 2005
  4. ncbi request reprint The unusual extended signal peptide region of the type V secretion system is phylogenetically restricted
    Mickael Desvaux
    Division of Immunity and Infection, The University of Birmingham, Edgbaston, Birmingham, UK
    FEMS Microbiol Lett 264:22-30. 2006
  5. ncbi request reprint Protein secretion systems in Fusobacterium nucleatum: genomic identification of Type 4 piliation and complete Type V pathways brings new insight into mechanisms of pathogenesis
    Mickael Desvaux
    The Institute for Biomedical Research IBR, The University of Birmingham The Medical School, Division of Immunity and Infection, Bacterial Pathogenesis and Genomics Unit, Edgbaston, Birmingham B15 2TT, UK
    Biochim Biophys Acta 1713:92-112. 2005
  6. ncbi request reprint A conserved extended signal peptide region directs posttranslational protein translocation via a novel mechanism
    Mickael Desvaux
    Division of Immunity and Infection, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Microbiology 153:59-70. 2007
  7. ncbi request reprint Type V protein secretion: simplicity gone awry?
    Mickael Desvaux
    Bacterial Pathogenesis and Genomics Unit, Division of Immunity and Infection, The University of Birmingham, The Medical School, Edgbaston, Birmingham B15 2TT, UK
    Curr Issues Mol Biol 6:111-24. 2004
  8. doi request reprint Transcription of the plasmid-encoded toxin gene from enteroaggregative Escherichia coli is regulated by a novel co-activation mechanism involving CRP and Fis
    Amanda E Rossiter
    School of Immunity and Infection School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK
    Mol Microbiol 81:179-91. 2011
  9. ncbi request reprint The autotransporter secretion system
    Mickael Desvaux
    Bacterial Pathogenesis and Genomics Unit, Division of Immunity and Infection, The Medical School, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
    Res Microbiol 155:53-60. 2004
  10. pmc Type V protein secretion pathway: the autotransporter story
    Ian R Henderson
    Division of Immunity and Infection, University of Birmingham, Birmingham B15 2TT, UK
    Microbiol Mol Biol Rev 68:692-744. 2004

Collaborators

Detail Information

Publications11

  1. ncbi request reprint The general secretory pathway: a general misnomer?
    Mickael Desvaux
    Institute for Biomedical Research, The University of Birmingham The Medical School, Division of Immunity and Infection, Bacterial Pathogenesis and Genomics Unit, Vincent Drive, Edgbaston, Birmingham, UK B15 2TT
    Trends Microbiol 12:306-9. 2004
    ..By putting the record straight and using novel findings within the field of bacterial protein secretion, we hope to bring clarity to this area of science and prevent further promulgation of incorrect terminologies...
  2. ncbi request reprint Genomic analysis of the protein secretion systems in Clostridium acetobutylicum ATCC 824
    Mickael Desvaux
    The Institute for Biomedical Research IBR, The University of Birmingham The Medical School, Division of Immunity and Infection, Bacterial Pathogenesis and Genomics Unit, Edgbaston, Birmingham B15 2TT, UK
    Biochim Biophys Acta 1745:223-53. 2005
    ..This investigation highlights the potential use of this saprophytic bacterium in biotechnological and biomedical applications as well as a model organism for studying protein secretion in pathogenic Gram-positive bacteria...
  3. ncbi request reprint Clostridium cellulolyticum: model organism of mesophilic cellulolytic clostridia
    Mickael Desvaux
    Institute for Biomedical Research, The University of Birmingham The Medical School, Edgbaston, UK
    FEMS Microbiol Rev 29:741-64. 2005
    ..This in-depth analysis of C. cellulolyticum metabolism has permitted the first attempt to engineer metabolically a cellulolytic microorganism...
  4. ncbi request reprint The unusual extended signal peptide region of the type V secretion system is phylogenetically restricted
    Mickael Desvaux
    Division of Immunity and Infection, The University of Birmingham, Edgbaston, Birmingham, UK
    FEMS Microbiol Lett 264:22-30. 2006
    ..In vitro approaches demonstrate that the DNA region encoding the extended signal peptide region is transcribed and translated...
  5. ncbi request reprint Protein secretion systems in Fusobacterium nucleatum: genomic identification of Type 4 piliation and complete Type V pathways brings new insight into mechanisms of pathogenesis
    Mickael Desvaux
    The Institute for Biomedical Research IBR, The University of Birmingham The Medical School, Division of Immunity and Infection, Bacterial Pathogenesis and Genomics Unit, Edgbaston, Birmingham B15 2TT, UK
    Biochim Biophys Acta 1713:92-112. 2005
    ..B.12.), Type Vb (two-partner secretion system; TC #1.B.20.) and Type Vc (YadA-like trimeric autotransporter; TC #1.B.42.), was found. This work provides new insight into the protein secretion and virulence mechanisms of F. nucleatum...
  6. ncbi request reprint A conserved extended signal peptide region directs posttranslational protein translocation via a novel mechanism
    Mickael Desvaux
    Division of Immunity and Infection, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Microbiology 153:59-70. 2007
    ..Mutational analysis suggests that the ESPR delays inner membrane translocation by adopting a particular conformation, or by interacting with a cytoplasmic or inner membrane co-factor, prior to inner membrane translocation...
  7. ncbi request reprint Type V protein secretion: simplicity gone awry?
    Mickael Desvaux
    Bacterial Pathogenesis and Genomics Unit, Division of Immunity and Infection, The University of Birmingham, The Medical School, Edgbaston, Birmingham B15 2TT, UK
    Curr Issues Mol Biol 6:111-24. 2004
    ....
  8. doi request reprint Transcription of the plasmid-encoded toxin gene from enteroaggregative Escherichia coli is regulated by a novel co-activation mechanism involving CRP and Fis
    Amanda E Rossiter
    School of Immunity and Infection School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK
    Mol Microbiol 81:179-91. 2011
    ..This study complements previous findings that establish Fis as a key virulence regulator in EAEC 042...
  9. ncbi request reprint The autotransporter secretion system
    Mickael Desvaux
    Bacterial Pathogenesis and Genomics Unit, Division of Immunity and Infection, The Medical School, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
    Res Microbiol 155:53-60. 2004
    ..The autotransporter secretion process involving first the translocation of the precursor through the inner membrane and then its translocation through the outer membrane via a pore formed by a beta-barrel is reviewed...
  10. pmc Type V protein secretion pathway: the autotransporter story
    Ian R Henderson
    Division of Immunity and Infection, University of Birmingham, Birmingham B15 2TT, UK
    Microbiol Mol Biol Rev 68:692-744. 2004
    ..In light of new discoveries and controversies in this research field, this review considers the autotransporter secretion process in the context of the more general field of bacterial protein translocation and exoprotein function...
  11. doi request reprint The Escherichia coli biofilm-promoting protein Antigen 43 does not contribute to intestinal colonization
    Maria das Graças de Luna
    Division of Immunity and Infection, The Medical School, University of Birmingham, Birmingham, UK
    FEMS Microbiol Lett 284:237-46. 2008
    ..Unexpectedly, considering its similarity to other adhesins, our findings suggest that Ag43 does not act as a direct colonization factor by binding to mammalian cells...