Martin S Dennis

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. ncbi request reprint Effective prophylaxis for deep vein thrombosis after stroke: low-dose anticoagulation rather than stockings alone: against
    Martin S Dennis
    Neuroscience Trials Unit, University of Edinburgh, Bramwell Dott Building, Western General Hospitals NHS Trust, Crewe Road, Edinburgh, UK
    Stroke 35:2912-3. 2004
  2. ncbi request reprint A quantitative study of the emotional outcome of people caring for stroke survivors
    M Dennis
    Department of Clinical Neurosciences, The University of Edinburgh, Scotland
    Stroke 29:1867-72. 1998
  3. pmc Commentary: an imperfect compromise
    Martin Dennis
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU
    BMJ 327:286. 2003
  4. ncbi request reprint Outcome after brain haemorrhage
    Martin S Dennis
    Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK
    Cerebrovasc Dis 16:9-13. 2003
  5. ncbi request reprint Stroke services in Scotland
    Martin Dennis
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Cerebrovasc Dis 15:26-8. 2003
  6. ncbi request reprint Fractures after stroke: frequency, types, and associations
    M S Dennis
    Department of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK
    Stroke 33:728-34. 2002
  7. pmc Emotional outcomes after stroke: factors associated with poor outcome
    M Dennis
    Neurosciences Trials Unit, Department of Clinical Neurosciences, The University of Edinburgh, Bramwell Dott Building, Western General Hospital, Crewe Rd, Edinburgh, EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 68:47-52. 2000
  8. ncbi request reprint Associations between diffusion and perfusion parameters, N-acetyl aspartate, and lactate in acute ischemic stroke
    Vera Cvoro
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, UK
    Stroke 40:767-72. 2009
  9. doi request reprint MR diffusion and perfusion parameters: relationship to metabolites in acute ischaemic stroke
    Vera Cvoro
    SFC Brain Imaging Research Centre, SINAPSE Collaboration, Division of Clinical Neuroscience, Western General Hospital, Crewe Rd, Edinburgh EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 81:185-91. 2010
  10. pmc Relationships between brain and body temperature, clinical and imaging outcomes after ischemic stroke
    Bartosz Karaszewski
    Brain Research Imaging Centre, Division of Neuroimaging Sciences, SINAPSE Collaboration, University of Edinburgh, Edinburgh, UK
    J Cereb Blood Flow Metab 33:1083-9. 2013

Detail Information

Publications76

  1. ncbi request reprint Effective prophylaxis for deep vein thrombosis after stroke: low-dose anticoagulation rather than stockings alone: against
    Martin S Dennis
    Neuroscience Trials Unit, University of Edinburgh, Bramwell Dott Building, Western General Hospitals NHS Trust, Crewe Road, Edinburgh, UK
    Stroke 35:2912-3. 2004
  2. ncbi request reprint A quantitative study of the emotional outcome of people caring for stroke survivors
    M Dennis
    Department of Clinical Neurosciences, The University of Edinburgh, Scotland
    Stroke 29:1867-72. 1998
    ..We aimed to describe the outcome of those caring for stroke patients and to identify both patient and caregiver factors that are associated with poor caregiver outcomes...
  3. pmc Commentary: an imperfect compromise
    Martin Dennis
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU
    BMJ 327:286. 2003
  4. ncbi request reprint Outcome after brain haemorrhage
    Martin S Dennis
    Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK
    Cerebrovasc Dis 16:9-13. 2003
    ..Pooling of data from community-based studies of haemorrhagic stroke that have used consistent definitions and methods represents the only feasible way to obtain more precise data on prognosis after intracerebral haemorrhage...
  5. ncbi request reprint Stroke services in Scotland
    Martin Dennis
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Cerebrovasc Dis 15:26-8. 2003
    ..A national system to monitor the progress of the strategy is being developed...
  6. ncbi request reprint Fractures after stroke: frequency, types, and associations
    M S Dennis
    Department of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK
    Stroke 33:728-34. 2002
    ..Stroke patients may have an increased risk of fractures because of weak bones or an increased risk of falling. Our goal was to estimate the frequency of fracture after stroke and to identify those at greatest risk...
  7. pmc Emotional outcomes after stroke: factors associated with poor outcome
    M Dennis
    Neurosciences Trials Unit, Department of Clinical Neurosciences, The University of Edinburgh, Bramwell Dott Building, Western General Hospital, Crewe Rd, Edinburgh, EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 68:47-52. 2000
    ....
  8. ncbi request reprint Associations between diffusion and perfusion parameters, N-acetyl aspartate, and lactate in acute ischemic stroke
    Vera Cvoro
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, UK
    Stroke 40:767-72. 2009
    ..We used spectroscopic imaging to measure N-acetyl aspartate (NAA, a marker of normal neurons) and lactate (a marker of ischemia) to compare with diffusion and perfusion values in the diffusion lesion in acute ischemic stroke...
  9. doi request reprint MR diffusion and perfusion parameters: relationship to metabolites in acute ischaemic stroke
    Vera Cvoro
    SFC Brain Imaging Research Centre, SINAPSE Collaboration, Division of Clinical Neuroscience, Western General Hospital, Crewe Rd, Edinburgh EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 81:185-91. 2010
    ..The authors compared N-acetyl aspartate (NAA, found in intact neurons) and lactate (anaerobic metabolism) with diffusion/perfusion parameters...
  10. pmc Relationships between brain and body temperature, clinical and imaging outcomes after ischemic stroke
    Bartosz Karaszewski
    Brain Research Imaging Centre, Division of Neuroimaging Sciences, SINAPSE Collaboration, University of Edinburgh, Edinburgh, UK
    J Cereb Blood Flow Metab 33:1083-9. 2013
    ....
  11. doi request reprint Differences between ischemic stroke subtypes in vascular outcomes support a distinct lacunar ischemic stroke arteriopathy: a prospective, hospital-based study
    Caroline A Jackson
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU
    Stroke 40:3679-84. 2009
    ..Different risks of recurrent stroke and MI after lacunar versus nonlacunar ischemic stroke may support a distinct lacunar arteriopathy...
  12. ncbi request reprint Apparent diffusion coefficient thresholds and diffusion lesion volume in acute stroke
    Ralph G R Thomas
    Brain Research Imaging Centre, Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom Scottish Imaging Network, A Platform for Scientific Collaboration SINAPSE
    J Stroke Cerebrovasc Dis 22:906-9. 2013
    ....
  13. doi request reprint Counting cavitating lacunes underestimates the burden of lacunar infarction
    Gillian M Potter
    Division of Clinical Neurosciences and SINAPSE Collaboration, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom
    Stroke 41:267-72. 2010
    ..The proportion of symptomatic lacunar infarcts that progress to lacunes is unknown. Noncavitating lacunar infarcts may continue to resemble white matter lesions...
  14. pmc Abnormal breathing patterns in stroke: relationship with location of acute stroke lesion and prior cerebrovascular disease
    Anne M Rowat
    School of Nursing, Midwifery and Social Care, Napier University, Canaan Lane Campus, Edinburgh EH9 2TB, Scotland, UK
    J Neurol Neurosurg Psychiatry 78:277-9. 2007
    ..To determine whether central periodic breathing (CPB) is associated with acute involvement of any particular part of the brain, or the extent of total damage in patients with acute stroke...
  15. ncbi request reprint Clinically relevant fatigue in cancer outpatients: the Edinburgh Cancer Centre symptom study
    D J Storey
    Edinburgh Cancer Centre, Western General Hospital, Edinburgh, UK
    Ann Oncol 18:1861-9. 2007
    ..We aimed to determine the prevalence of clinically relevant fatigue (CRF) and its associations in outpatients with various cancer diagnoses...
  16. pmc Temporal profile of body temperature in acute ischemic stroke: relation to stroke severity and outcome
    Bartosz Karaszewski
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Rd, Edinburgh EH4 2XU, UK
    BMC Neurol 12:123. 2012
    ..Pyrexia after stroke (temperature ≥37.5°C) is associated with poor prognosis, but information on timing of body temperature changes and relationship to stroke severity and subtypes varies...
  17. pmc Lack of association of white matter lesions with ipsilateral carotid artery stenosis
    Gillian M Potter
    Division of Clinical Neurosciences, Brain Research Imaging Centre, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Cerebrovasc Dis 33:378-84. 2012
    ..A role for carotid artery atherothromboemboli has been suggested. If this is the case, more WML would be expected ipsilateral to increasing degrees of carotid stenosis...
  18. pmc Patients whom neurologists find difficult to help
    A J Carson
    Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Royal Edinburgh Hospital, UK
    J Neurol Neurosurg Psychiatry 75:1776-8. 2004
    ..All doctors recognise that some patients are more "difficult to help" than others, but the issue has received little systematic investigation in neurological practice...
  19. pmc Blood-brain barrier permeability and long-term clinical and imaging outcomes in cerebral small vessel disease
    Joanna M Wardlaw
    Brain Research Imaging Center, Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, United Kingdom
    Stroke 44:525-7. 2013
    ..Increased blood-brain barrier (BBB) permeability occurs in cerebral small vessel disease. It is not known if BBB changes predate progression of small vessel disease...
  20. ncbi request reprint Cerebral microbleeds are associated with lacunar stroke defined clinically and radiologically, independently of white matter lesions
    Joanna M Wardlaw
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Rd, Edinburgh, EH4 2EX, UK
    Stroke 37:2633-6. 2006
    ..An association between microbleeds and clinically defined lacunar stroke might suggest a common causal microangiopathy...
  21. ncbi request reprint Central periodic breathing observed on hospital admission is associated with an adverse prognosis in conscious acute stroke patients
    Anne M Rowat
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Cerebrovasc Dis 21:340-7. 2006
    ..Central periodic breathing (CPB) is common following acute stroke, but its prognostic significance is uncertain. We determined the frequency of CPB on admission with stroke and assessed whether it was related to outcome...
  22. doi request reprint Early brain temperature elevation and anaerobic metabolism in human acute ischaemic stroke
    Bartosz Karaszewski
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Rd, Edinburgh, EH4 2XU, UK
    Brain 132:955-64. 2009
    ..Further studies are required to determine why early brain temperature elevation is highest in potential penumbral tissue...
  23. doi request reprint Characteristics of patients with minor ischaemic strokes and negative MRI: a cross-sectional study
    Fergus N Doubal
    Division of Clinical Neurosciences, Bramwell Dott Building, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 82:540-2. 2011
    ..BACKGROUND Diffusion-weighted (DWI) MRI is recommended in UK guidelines to evaluate minor strokes, yet can produce negative results...
  24. ncbi request reprint Clinical scores for the identification of stroke and transient ischaemic attack in the emergency department: a cross-sectional study
    William N Whiteley
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 82:1006-10. 2011
    ..To compare the sensitivity and specificity of bedside diagnostic stroke scales in patients with suspected stroke...
  25. ncbi request reprint Medically unexplained symptoms in patients referred to a specialist rheumatology service: prevalence and associations
    N L Maiden
    Rheumatic Diseases Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    Rheumatology (Oxford) 42:108-12. 2003
    ....
  26. pmc Vascular risk factors, large-artery atheroma, and brain white matter hyperintensities
    Joanna M Wardlaw
    From the Centre for Clinical Brain Sciences J M W, F N D, M V H, Z M, M B, M S D and Centre for Cognitive Ageing and Cognitive Epidemiology M A, M V H, A J G, M B, J M S, I J D, University of Edinburgh, UK
    Neurology 82:1331-8. 2014
    ..To determine the magnitude of potentially causal relationships among vascular risk factors (VRFs), large-artery atheromatous disease (LAD), and cerebral white matter hyperintensities (WMH) in 2 prospective cohorts...
  27. doi request reprint Stroke unit care benefits patients with intracerebral hemorrhage: systematic review and meta-analysis
    Peter Langhorne
    From the Academic Section of Geriatric Medicine, Royal Infirmary, Glasgow, United Kingdom P L, P F Department of Neurology, Akershus University Hospital, Norway O M R Department of Neurology, Helsinki University Central Hospital, Finland M K, H P Acute Stroke Unit, Department of Clinical Therapeutics, School of Medicine, University of Ioannina, Greece K V Department of Stroke Medicine, King s College Hospital, London, United Kingdom L K Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway B I Institute of Clinical Neuroscience, Sahlgrenska University Hospital, Goteborg University, Sweden C B Institute of Ageing and Health, Medical School, Newcastle upon Tyne, United Kingdom H R and Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, United Kingdom M S D, R A S S
    Stroke 44:3044-9. 2013
    ..However, it is uncertain whether these benefits apply equally to patients with intracerebral hemorrhage and ischemic stroke...
  28. pmc Cognitive impairment after lacunar stroke: systematic review and meta-analysis of incidence, prevalence and comparison with other stroke subtypes
    Stephen David James Makin
    Division of Clinical Neurosciences, University of Edinburgh, Bramwell Dott Building, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 84:893-900. 2013
    ..Lacunar strokes might be less likely to affect cognition than more severe, larger cortical strokes, except that lacunar strokes are associated with cerebral small vessel disease (SVD), which is the commonest vascular cause of dementia...
  29. ncbi request reprint Persistent infarct hyperintensity on diffusion-weighted imaging late after stroke indicates heterogeneous, delayed, infarct evolution
    Carly S Rivers
    Division of Clinical Neurosciences, Western General Hospital, Edinburgh, UK
    Stroke 37:1418-23. 2006
    ..We hypothesized that late DWI hyperintensity reflected different infarct evolution compared with areas that were isointense by 1 month...
  30. doi request reprint Enlarged perivascular spaces on MRI are a feature of cerebral small vessel disease
    Fergus N Doubal
    MRCP, Division of Clinical Neurosciences, Bramwell Dott Building, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK
    Stroke 41:450-4. 2010
    ..We determined whether enlarged perivascular spaces were associated with lacunar stroke subtype and white matter hyperintensities, markers of established small vessel disease. Materials and..
  31. pmc The outcome of neurology outpatients with medically unexplained symptoms: a prospective cohort study
    A J Carson
    Robert Fergusson Unit, Royal Edinburgh Hospital, Edinburgh, UK
    J Neurol Neurosurg Psychiatry 74:897-900. 2003
    ..In a previous cross sectional study of 300 consecutive new attenders at neurology outpatient clinics, 90 were detected with symptoms that were rated as "not at all" or only "somewhat" explained by organic disease...
  32. doi request reprint Disability, distress and unemployment in neurology outpatients with symptoms 'unexplained by organic disease'
    A Carson
    School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, UK
    J Neurol Neurosurg Psychiatry 82:810-3. 2011
    ..To determine the disability, distress and employment status of new neurology outpatients with physical symptoms unexplained by organic disease and to compare them with patients with symptoms explained by organic disease...
  33. pmc Emotional distress in cancer patients: the Edinburgh Cancer Centre symptom study
    V Strong
    School of Molecular and Clinical Medicine, Cancer Research UK and The University of Edinburgh Cancer Research Centre, The Western General Hospital, Crewe Road, Edinburgh EH4 2XR, UK
    Br J Cancer 96:868-74. 2007
    ..Services to treat distress in cancer patients should be organised to target patients by characteristics other than their cancer diagnosis...
  34. doi request reprint Who is referred to neurology clinics?--the diagnoses made in 3781 new patients
    J Stone
    School of Molecular and Clinical Medicine, University of Edinburgh, United Kingdom
    Clin Neurol Neurosurg 112:747-51. 2010
    ..Previous studies of this topic have been limited by being of only single centres or lacking in detail. We aimed to describe the neurological diagnoses made in a large series of referrals to neurology outpatient clinics...
  35. pmc Are functional motor and sensory symptoms really more frequent on the left? A systematic review
    J Stone
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Road, UK
    J Neurol Neurosurg Psychiatry 73:578-81. 2002
    ..To test the hypothesis that unilateral motor and sensory symptoms unexplained by identifiable disease are more common on the left side of the body than the right...
  36. ncbi request reprint Symptoms 'unexplained by organic disease' in 1144 new neurology out-patients: how often does the diagnosis change at follow-up?
    Jon Stone
    Division of Clinical Neurosciences, School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Brain 132:2878-88. 2009
    ..A new diagnosis, which with hindsight explained the original symptoms, rarely became apparent to the patient's primary care doctor in the 18 months following the initial hospital consultation...
  37. ncbi request reprint Quantifying the burden of emotional ill-health amongst patients referred to a specialist rheumatology service
    N L Maiden
    Rheumatic Diseases Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    Rheumatology (Oxford) 42:750-7. 2003
    ....
  38. pmc The 12 year prognosis of unilateral functional weakness and sensory disturbance
    J Stone
    Division of Clinical Neurosciences, School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, UK
    J Neurol Neurosurg Psychiatry 74:591-6. 2003
    ..Although the symptoms of unilateral "medically unexplained" or "functional" weakness and sensory disturbance present commonly to neurologists, little is known about their long term prognosis...
  39. pmc Functional weakness and sensory disturbance
    J Stone
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    J Neurol Neurosurg Psychiatry 73:241-5. 2002
    ..It should be borne in mind that a patient may have both a functional and an organic disorder...
  40. pmc Personality change after stroke: some preliminary observations
    J Stone
    Division of Clinical Neurosciences, School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK
    J Neurol Neurosurg Psychiatry 75:1708-13. 2004
    ..To describe changes in personality after stroke and effects on carers...
  41. doi request reprint Neurology out-patients with symptoms unexplained by disease: illness beliefs and financial benefits predict 1-year outcome
    M Sharpe
    Psychological Medicine Research, School of Molecular and Clinical Medicine, University of Edinburgh, UK
    Psychol Med 40:689-98. 2010
    ..We therefore aimed to determine predictors of poor subjective outcome for new neurology out-patients with symptoms unexplained by disease 1 year after the initial consultation...
  42. ncbi request reprint What do medical outpatients attending a neurology clinic think about antidepressants?
    J Stone
    Division of Clinical Neurosciences, School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    J Psychosom Res 56:293-5. 2004
    ....
  43. pmc Major depression in outpatients attending a regional cancer centre: screening and unmet treatment needs
    M Sharpe
    Division of Psychiatry, School of Molecular and Clinical Medicine, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, UK
    Br J Cancer 90:314-20. 2004
    ..Very few had received psychological treatment or had been referred to mental health services. Most were receiving no potentially effective therapy...
  44. pmc Functional symptoms in neurology: management
    J Stone
    Department of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 76:i13-21. 2005
  45. pmc Functional symptoms and signs in neurology: assessment and diagnosis
    J Stone
    Department of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 76:i2-12. 2005
  46. pmc Internet resources for psychiatry and neuropsychiatry
    J Stone
    Department of Clinical Neurosciences, Western General Hospital, Crewe Rd, Edinburgh EH4 2XU, Scotland, UK
    J Neurol Neurosurg Psychiatry 74:10-2. 2003
  47. pmc Neurological disease, emotional disorder, and disability: they are related: a study of 300 consecutive new referrals to a neurology outpatient department
    A J Carson
    Department of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, Scotland, UK
    J Neurol Neurosurg Psychiatry 68:202-6. 2000
    ....
  48. pmc Do medically unexplained symptoms matter? A prospective cohort study of 300 new referrals to neurology outpatient clinics
    A J Carson
    University Department of Psychiatry, Kennedy Tower, Royal Edinburgh Hospital, Edinburgh EH10 5HF, UK
    J Neurol Neurosurg Psychiatry 68:207-10. 2000
    ....
  49. ncbi request reprint Depression after stroke and lesion location: a systematic review
    A J Carson
    University Department of Psychiatry, Royal Edinburgh Hospital, UK
    Lancet 356:122-6. 2000
    ..We undertook a systematic review to examine the hypotheses that depression is more commonly associated with left-hemisphere strokes than with right-hemisphere strokes and with lesions of the left anterior brain than with other regions...
  50. pmc Management of major depression in outpatients attending a cancer centre: a preliminary evaluation of a multicomponent cancer nurse-delivered intervention
    M Sharpe
    Division of Psychiatry, School of Molecular and Clinical Medicine, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, UK
    Br J Cancer 90:310-3. 2004
    ..At the final 6-month outcome, 38.5% (95% CI, 5.4-57%) fewer patients in the intervention group still met the criteria for MDD...
  51. pmc Research governance impediments to clinical trials: a retrospective survey
    Rustam Al-Shahi Salman
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    J R Soc Med 100:101-4. 2007
    ..We sought to evaluate the delays, between-centre variations in practice, and opportunity costs attributable to delays in research governance approval of clinical trials in the United Kingdom...
  52. ncbi request reprint Relationship between absolute mean cerebral transit time and absolute mean flow velocity on transcranial Doppler ultrasound after ischemic stroke
    Joanna M Wardlaw
    Department of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, United Kingdom
    J Neuroimaging 12:104-11. 2002
    ..However, a simple measure of absolute mean flow velocity might provide a direct assessment of "perfusion reserve" in acute ischemic stroke...
  53. pmc Retinal arteriolar geometry is associated with cerebral white matter hyperintensities on magnetic resonance imaging
    Fergus N Doubal
    Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK
    Int J Stroke 5:434-9. 2010
    ..Retinal vessels show developmental and pathophysiological similarities to cerebral small vessels and microvessel geometry may influence vascular efficiency...
  54. ncbi request reprint Extensive haemorrhagic transformation of infarct: might it be an important cause of primary intracerebral haemorrhage?
    Gillian E Mead
    Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK
    Age Ageing 31:429-33. 2002
    ....
  55. ncbi request reprint Sleep-disordered breathing as a risk factor for cerebrovascular disease: a case-control study in patients with transient ischemic attacks
    Nigel McArdle
    Department of Medicine, University of Edinburgh, Royal Infirmary, Edinburgh, UK
    Stroke 34:2916-21. 2003
    ..We explored this relationship in transient ischemic attack (TIA) patients because they are less likely than stroke patients to have OSAH as a consequence of cerebrovascular disease...
  56. pmc Fatigue after stroke: baseline predictors and influence on survival. Analysis of data from UK patients recruited in the International Stroke Trial
    Gillian E Mead
    University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 6:e16988. 2011
    ..The vitality component of the Short Form 36 (SF-36) is a valid and reliable measure of post-stroke fatigue. We sought to identify associates of post-stroke fatigue and determine whether fatigue predicted survival...
  57. ncbi request reprint Hypoxaemia in acute stroke is frequent and worsens outcome
    Anne M Rowat
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK
    Cerebrovasc Dis 21:166-72. 2006
    ..Hypoxaemia in the acute phase of stroke might damage the ischaemic penumbra and worsen clinical outcome. We determined the frequency of hypoxaemia on admission with stroke and assessed whether it was related to outcome...
  58. ncbi request reprint Interobserver agreement for the bedside clinical assessment of suspected stroke
    Peter J Hand
    Division of Clinical Neurosciences, Western General Hospital, Edinburgh, UK
    Stroke 37:776-80. 2006
    ..We aimed to measure inter-rater reliability for the clinical assessment of stroke, with emphasis on items of history, timing of symptom onset, and diagnosis of stroke or mimic. We explored reasons for poor reliability...
  59. pmc The outcome of depressive disorders in neurology patients: a prospective cohort study
    A J Carson
    Royal Edinburgh Hospital and Western General Hospital, Edinburgh, UK
    J Neurol Neurosurg Psychiatry 74:893-6. 2003
    ..In a previous prospective study of 300 consecutive new attenders at neurology outpatient clinics, depressive disorders were diagnosed in 119 patients (40%) and major depressive disorder in 77 (26%)...
  60. doi request reprint Fatigue after stroke: a systematic review of associations with impaired physical fitness
    Fiona Duncan
    Geriatric Medicine, University of Edinburgh, UK
    Int J Stroke 7:157-62. 2012
    ..If an association between physical activity and fatigue after stroke could be established, this would provide a rationale for developing a physical activity-based treatment...
  61. pmc Retinopathy in ischemic stroke subtypes
    Fergus N Doubal
    Division of Clinical Neurosciences, Western General Hospital, Edinburgh, UK
    Stroke 40:389-93. 2009
    ..We hypothesized that there would be higher rates of retinopathy in patients with acute lacunar versus cortical stroke...
  62. ncbi request reprint Study of the relationship between social deprivation and outcome after stroke
    Nicolas U Weir
    Department of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh, Scotland
    Stroke 36:815-9. 2005
    ..This study has investigated the relationship between SES and case fatality, "death or dependency," and "death or institutional care" at 6 months after stroke...
  63. ncbi request reprint Two cases of recurrent stroke in treated giant cell arteritis: diagnostic and therapeutic dilemmas
    Alasdair J Fitzgerald
    Department of Rehabilitation Medicine, Astley Ainslie Hospital, Edinburgh, Scotland
    J Clin Rheumatol 16:225-8. 2010
    ..There is a need to develop effective means of monitoring GCA activity and to determine the most effective treatment approach in this circumstance...
  64. ncbi request reprint Senior physicians' estimates of the likely effects of feeding policies on outcomes prior to the completion of the FOOD trials
    Martin S Dennis
    Clinical Neurosciences, University of Edinburgh, Edinburgh, Scotland, UK
    Age Ageing 35:185-7. 2006
  65. ncbi request reprint Comparison of risk factors in patients with transient and prolonged eye and brain ischemic syndromes
    Gillian E Mead
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, Scotland
    Stroke 33:2383-90. 2002
    ....
  66. doi request reprint Frequent medical absences in secondary school students: survey and case-control study
    R Jones
    Royal Hospital for Sick Children, Edinburgh, UK
    Arch Dis Child 94:763-7. 2009
    ....
  67. ncbi request reprint Negative attitudes among short-term stroke survivors predict worse long-term survival
    S C Lewis
    Department of Clinical Neurosciences, University of Edinburgh, Scotland
    Stroke 32:1640-5. 2001
    ..These findings need to be confirmed and any causal relationship between attitude and survival further explored in a randomized controlled trial to "improve" the attitude of stroke patients toward their illness...
  68. doi request reprint Changes in background blood-brain barrier integrity between lacunar and cortical ischemic stroke subtypes
    Joanna M Wardlaw
    Stroke 39:1327-32. 2008
    ..Endothelial dysfunction could impair blood-brain barrier integrity. We assessed background blood-brain barrier leakage in patients with lacunar ischemic stroke compared with cortical stroke controls...
  69. ncbi request reprint Measurement of brain temperature with magnetic resonance spectroscopy in acute ischemic stroke
    Bartosz Karaszewski
    Department of Neurology of Adults, Medical University of Gdansk, Gdansk, Poland
    Ann Neurol 60:438-46. 2006
    ..We used magnetic resonance spectroscopic imaging (water-to-N-acetylaspartate frequency shift) to measure cerebral temperature noninvasively in stroke patients...
  70. ncbi request reprint The impact of neuroimaging on clinical decisions in minor stroke
    Sarah L Keir
    Age Ageing 33:312-4. 2004
  71. ncbi request reprint Granulocyte-colony-stimulating factor mobilizes bone marrow stem cells in patients with subacute ischemic stroke: the Stem cell Trial of recovery EnhanceMent after Stroke (STEMS) pilot randomized, controlled trial (ISRCTN 16784092)
    Nikola Sprigg
    Institute of Neuroscience, University of Nottingham, Nottingham, UK
    Stroke 37:2979-83. 2006
    ..We assessed the safety of granulocyte-colony-stimulating factor (G-CSF) after stroke and its effect on circulating CD34+ stem cells...
  72. ncbi request reprint Distinguishing between stroke and mimic at the bedside: the brain attack study
    Peter J Hand
    Stroke Centre, Department of Neurology, Royal Melbourne Hospital, Monash University, Victoria, Australia
    Stroke 37:769-75. 2006
    ..We aimed to determine the frequency and nature of stroke mimics and to identify the key clinical features that distinguish between stroke and mimic at the bedside...
  73. ncbi request reprint Acute ischemic stroke lesion measurement on diffusion-weighted imaging--important considerations in designing acute stroke trials with magnetic resonance imaging
    Carly S Rivers
    Clinical Trials Research Unit, University of Leeds, Leeds, United Kingdom
    J Stroke Cerebrovasc Dis 16:64-70. 2007
    ..Little is known of what factors might affect DWI lesion size measurement. We examined morphologic factors that might affect DWI lesion measurement...
  74. ncbi request reprint Predicting outcome in hyper-acute stroke: validation of a prognostic model in the Third International Stroke Trial (IST3)
    Steff C Lewis
    J Neurol Neurosurg Psychiatry 79:397-400. 2008
    ..The explanatory variables in the model are age, living alone, independent pre-stroke, Glasgow Coma Scale verbal score, ability to lift arms and ability to walk...
  75. ncbi request reprint Stroke units: the next 10 years
    Peter Langhorne
    Academic Section of Geriatric Medicine, Royal Infirmary, Glasgow G4 OSF, UK
    Lancet 363:834-5. 2004