G C DeLuca

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. doi request reprint Casting light on multiple sclerosis heterogeneity: the role of HLA-DRB1 on spinal cord pathology
    Gabriele C DeLuca
    Nuffield Department of Clinical Neurosciences Neuropathology Level 1, West Wing, John Radcliffe Hospital Headley Way, Headington, Oxford, OX3 9DU, UK
    Brain 136:1025-34. 2013
  2. doi request reprint Review: the role of vitamin D in nervous system health and disease
    G C DeLuca
    Nuffield Department of Clinical Neurosciences Clinical Neurology, University of Oxford, Oxford, UK
    Neuropathol Appl Neurobiol 39:458-84. 2013
  3. doi request reprint Risk alleles for multiple sclerosis in multiplex families
    M J D'Netto
    Wellcome Trust Centre for Human Genetics, Department of Clinical Neurology, University of Oxford, UK
    Neurology 72:1984-8. 2009
  4. ncbi request reprint The role of hereditary spastic paraplegia related genes in multiple sclerosis. A study of disease susceptibility and clinical outcome
    G C DeLuca
    University Dept of Clinical Neurology, University of Oxford, Radcliffe Infirmary, Woodstock Rd, Oxford, OX2 6LE, UK
    J Neurol 254:1221-6. 2007
  5. ncbi request reprint The contribution of demyelination to axonal loss in multiple sclerosis
    G C DeLuca
    Department of Clinical Neurology, University of Oxford, Oxford, UK
    Brain 129:1507-16. 2006
  6. ncbi request reprint Multiple sclerosis susceptibility and the X chromosome
    B M Herrera
    The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK, Department of Clinical Neurology, University of Oxford, Oxford, UK
    Mult Scler 13:856-64. 2007
  7. doi request reprint Age of puberty and the risk of multiple sclerosis: a population based study
    S V Ramagopalan
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Eur J Neurol 16:342-7. 2009
  8. ncbi request reprint No effect of APOE and PVRL2 on the clinical outcome of multiple sclerosis
    S V Ramagopalan
    Department of Clinical Neurology, University of Oxford, UK
    J Neuroimmunol 186:156-60. 2007
  9. ncbi request reprint The extent of axonal loss in the long tracts in hereditary spastic paraplegia
    G C DeLuca
    Departments of Clinical Neurology, University of Oxford, Oxford, UK
    Neuropathol Appl Neurobiol 30:576-84. 2004
  10. ncbi request reprint Evidence of axonal damage in human acute demyelinating diseases
    N Ghosh
    Department of Clinical Neurology, University of Oxford, UK
    J Neurol Sci 222:29-34. 2004

Collaborators

Detail Information

Publications13

  1. doi request reprint Casting light on multiple sclerosis heterogeneity: the role of HLA-DRB1 on spinal cord pathology
    Gabriele C DeLuca
    Nuffield Department of Clinical Neurosciences Neuropathology Level 1, West Wing, John Radcliffe Hospital Headley Way, Headington, Oxford, OX3 9DU, UK
    Brain 136:1025-34. 2013
    ..This study casts light on the role of HLA-DRB1*15 in disease outcome and highlights the powerful approach of using microscopic pathology to clarify the way in which genes and clinical phenotypes of neurological diseases are linked...
  2. doi request reprint Review: the role of vitamin D in nervous system health and disease
    G C DeLuca
    Nuffield Department of Clinical Neurosciences Clinical Neurology, University of Oxford, Oxford, UK
    Neuropathol Appl Neurobiol 39:458-84. 2013
    ..The strength of evidence varies for schizophrenia, autism, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease, and is especially strong for multiple sclerosis. ..
  3. doi request reprint Risk alleles for multiple sclerosis in multiplex families
    M J D'Netto
    Wellcome Trust Centre for Human Genetics, Department of Clinical Neurology, University of Oxford, UK
    Neurology 72:1984-8. 2009
    ....
  4. ncbi request reprint The role of hereditary spastic paraplegia related genes in multiple sclerosis. A study of disease susceptibility and clinical outcome
    G C DeLuca
    University Dept of Clinical Neurology, University of Oxford, Radcliffe Infirmary, Woodstock Rd, Oxford, OX2 6LE, UK
    J Neurol 254:1221-6. 2007
    ....
  5. ncbi request reprint The contribution of demyelination to axonal loss in multiple sclerosis
    G C DeLuca
    Department of Clinical Neurology, University of Oxford, Oxford, UK
    Brain 129:1507-16. 2006
    ..Since there was little correlation between plaque load and axonal loss, the possibility that demyelination is not the primary determinant of spinal cord axonal loss warrants consideration...
  6. ncbi request reprint Multiple sclerosis susceptibility and the X chromosome
    B M Herrera
    The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK, Department of Clinical Neurology, University of Oxford, Oxford, UK
    Mult Scler 13:856-64. 2007
    ..Complex interactions including epigenetic ones, and masking by balanced polymorphisms are mechanisms not excluded by the approach taken...
  7. doi request reprint Age of puberty and the risk of multiple sclerosis: a population based study
    S V Ramagopalan
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Eur J Neurol 16:342-7. 2009
    ..Given a potential role for sex hormones in MS, we have investigated whether or not the age of puberty influences the risk of developing MS in a population-based cohort...
  8. ncbi request reprint No effect of APOE and PVRL2 on the clinical outcome of multiple sclerosis
    S V Ramagopalan
    Department of Clinical Neurology, University of Oxford, UK
    J Neuroimmunol 186:156-60. 2007
    ..We conclude that APOE and PVRL2 have little or no effect on the clinical outcome of MS...
  9. ncbi request reprint The extent of axonal loss in the long tracts in hereditary spastic paraplegia
    G C DeLuca
    Departments of Clinical Neurology, University of Oxford, Oxford, UK
    Neuropathol Appl Neurobiol 30:576-84. 2004
    ..The characterization of the nature of axonal loss in HSP, where this is a primary phenomenon, may help the interpretation of axonal loss in conditions such as multiple sclerosis where the sequence of events is less clear...
  10. ncbi request reprint Evidence of axonal damage in human acute demyelinating diseases
    N Ghosh
    Department of Clinical Neurology, University of Oxford, UK
    J Neurol Sci 222:29-34. 2004
    ..Substantial axon damage, detected by immunostaining for beta amyloid precursor protein (betaAPP) has been demonstrated in acute demyelinating lesions in multiple sclerosis...
  11. pmc Vitamin D and multiple sclerosis hospital admissions in Scotland
    G Disanto
    Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford, OX3 7BN, UK
    QJM 104:1001-3. 2011
  12. ncbi request reprint TCR beta polymorphisms and multiple sclerosis
    D A Dyment
    Wellcome Trust Center for Human Genetics, Oxford, UK
    Genes Immun 5:337-42. 2004
    ..These results show no evidence for linkage and fail to establish an association between MS susceptibility and the TCR beta locus...
  13. ncbi request reprint Axonal loss in multiple sclerosis: a pathological survey of the corticospinal and sensory tracts
    G C DeLuca
    Department of Clinical Neurology, University of Oxford, Oxford, UK
    Brain 127:1009-18. 2004
    ..In multiple sclerosis, axonal loss is widespread, and its extent is tract specific and size selective...