Daniela Delneri

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. pmc Impact of chromosomal inversions on the yeast DAL cluster
    Samina Naseeb
    Life Sciences, University of Manchester, Manchester, United Kingdom
    PLoS ONE 7:e42022. 2012
  2. pmc Chimeric protein complexes in hybrid species generate novel phenotypes
    Elzbieta M Piatkowska
    Faculty of Life Sciences, Michael Smith Building, University of Manchester, Manchester, United Kingdom
    PLoS Genet 9:e1003836. 2013
  3. pmc The yeast factory
    Daniela Delneri
    Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PL, UK
    Genome Biol 13:320. 2012
  4. pmc Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection
    Nicoletta Bivi
    Department of Biomedical Sciences and Technologies, University of Udine, Piazzale Kolbe, 33100, Udine, Italy
    Genome Biol 10:R93. 2009
  5. pmc Application of the comprehensive set of heterozygous yeast deletion mutants to elucidate the molecular basis of cellular chromium toxicity
    Sara Holland
    School of Biology, Institute of Genetics, The University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Genome Biol 8:R268. 2007
  6. doi request reprint Barcode technology in yeast: application to pharmacogenomics
    Daniela Delneri
    Faculty of Life Sciences, University of Manchester, Manchester, UK
    FEMS Yeast Res 10:1083-9. 2010
  7. doi request reprint Competition experiments coupled with high-throughput analyses for functional genomics studies in yeast
    Daniela Delneri
    Faculty of Life Sciences, The University of Manchester, Manchester, UK
    Methods Mol Biol 759:271-82. 2011
  8. pmc Gene duplication and environmental adaptation within yeast populations
    Ryan M Ames
    Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
    Genome Biol Evol 2:591-601. 2010
  9. pmc Evolutionary systems biology of amino acid biosynthetic cost in yeast
    Michael D Barton
    Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
    PLoS ONE 5:e11935. 2010
  10. pmc Effects of reciprocal chromosomal translocations on the fitness of Saccharomyces cerevisiae
    Isabelle Colson
    School of Biological Sciences, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK
    EMBO Rep 5:392-8. 2004

Collaborators

Detail Information

Publications22

  1. pmc Impact of chromosomal inversions on the yeast DAL cluster
    Samina Naseeb
    Life Sciences, University of Manchester, Manchester, United Kingdom
    PLoS ONE 7:e42022. 2012
    ....
  2. pmc Chimeric protein complexes in hybrid species generate novel phenotypes
    Elzbieta M Piatkowska
    Faculty of Life Sciences, Michael Smith Building, University of Manchester, Manchester, United Kingdom
    PLoS Genet 9:e1003836. 2013
    ..The ability to exchange orthologous members has also important implications for the adaptation and subsequent genome evolution of the hybrids in terms of pattern of gene loss. ..
  3. pmc The yeast factory
    Daniela Delneri
    Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PL, UK
    Genome Biol 13:320. 2012
    ..A report on the 13th International Congress on Yeasts(ICY), held at Madison, Wisconsin, USA, 26-30 August 2012...
  4. pmc Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection
    Nicoletta Bivi
    Department of Biomedical Sciences and Technologies, University of Udine, Piazzale Kolbe, 33100, Udine, Italy
    Genome Biol 10:R93. 2009
    ..Strains carrying deletions in genes encoding potential drug targets show a variation of the intensity of their corresponding barcodes on the hybridization array over the time...
  5. pmc Application of the comprehensive set of heterozygous yeast deletion mutants to elucidate the molecular basis of cellular chromium toxicity
    Sara Holland
    School of Biology, Institute of Genetics, The University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Genome Biol 8:R268. 2007
    ..Microarray-based screens of these heterozygotes are truly genome-wide as they include both essential and non-essential genes...
  6. doi request reprint Barcode technology in yeast: application to pharmacogenomics
    Daniela Delneri
    Faculty of Life Sciences, University of Manchester, Manchester, UK
    FEMS Yeast Res 10:1083-9. 2010
    ..This review provides a focused overview of the achievements in the field of human medicine and pharmacology by exploiting the molecular tools available for yeast...
  7. doi request reprint Competition experiments coupled with high-throughput analyses for functional genomics studies in yeast
    Daniela Delneri
    Faculty of Life Sciences, The University of Manchester, Manchester, UK
    Methods Mol Biol 759:271-82. 2011
    ..In this chapter, the method used for implementation of competition experiments for high-throughput studies in yeast is presented...
  8. pmc Gene duplication and environmental adaptation within yeast populations
    Ryan M Ames
    Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
    Genome Biol Evol 2:591-601. 2010
    ..Together, these observations indicate that gene duplication can give rise to substantial phenotypic differences within populations that in turn can offer a shortcut to evolutionary adaptation...
  9. pmc Evolutionary systems biology of amino acid biosynthetic cost in yeast
    Michael D Barton
    Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
    PLoS ONE 5:e11935. 2010
    ....
  10. pmc Effects of reciprocal chromosomal translocations on the fitness of Saccharomyces cerevisiae
    Isabelle Colson
    School of Biological Sciences, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK
    EMBO Rep 5:392-8. 2004
    ..These results indicate that chromosomal translocations in Saccharomyces may have an adaptive significance, and lend support to a model of fixation by natural selection of reciprocal translocations in Saccharomyces species...
  11. pmc Characterization and prediction of haploinsufficiency using systems-level gene properties in yeast
    Matthew Norris
    Faculty of Life Sciences, University of Manchester, Manchester, Lancashire, M13 9PT, United Kingdom
    G3 (Bethesda) 3:1965-77. 2013
    ..Additionally, haploinsufficiency showed negative relationships with cell cycle regulation and promoter sequence conservation. ..
  12. ncbi request reprint Identification and characterization of high-flux-control genes of yeast through competition analyses in continuous cultures
    Daniela Delneri
    Faculty of Life Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK
    Nat Genet 40:113-7. 2008
    ..This chromosome determines a yeast's mating type, and the concentration of haploinsufficient genes there may be a mechanism to prevent its loss...
  13. pmc Fusel alcohols regulate translation initiation by inhibiting eIF2B to reduce ternary complex in a mechanism that may involve altering the integrity and dynamics of the eIF2B body
    Eleanor J Taylor
    Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, United Kingdom
    Mol Biol Cell 21:2202-16. 2010
    ..Overall, these results confirm that the guanine nucleotide exchange factor, eIF2B, is targeted by fusel alcohols. Moreover, they highlight a potential connection between the movement or integrity of the 2B body and eIF2B regulation...
  14. doi request reprint Transcriptome and proteome analysis of osteocytes treated with nitrogen-containing bisphosphonates
    Nicoletta Bivi
    Department of Biomedical Sciences and Technologies, University of Udine, Udine, Italy, Shimadzu Research Laboratory Europe, Manchester, UK
    J Proteome Res 8:1131-42. 2009
    ..Data validated using gel imaging in combination with the GLaD post digestion isotopic labeling method provide the molecular basis for understanding the role of bisphosphonates as antiapoptotic drugs for osteocytes...
  15. ncbi request reprint GIMS: an integrated data storage and analysis environment for genomic and functional data
    Michael Cornell
    Department of Computer Science, University of Manchester, Manchester M13 9PL, UK
    Yeast 20:1291-306. 2003
    ..The GIMS database can be accessed remotely using a Java application that can be downloaded from http://img.cs.man.ac.uk/gims...
  16. pmc Plasticity of genetic interactions in metabolic networks of yeast
    Richard Harrison
    Faculty of Life Sciences, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, United Kingdom
    Proc Natl Acad Sci U S A 104:2307-12. 2007
    ..Our work supports the view that functional redundancy may be more apparent than real, and it offers a unified framework for the evolution of environmental adaptation and mutational robustness...
  17. ncbi request reprint Engineering evolution to study speciation in yeasts
    Daniela Delneri
    School of Biological Sciences, University of Manchester, 2 205 Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Nature 422:68-72. 2003
    ..This controlled comparison of the effect of chromosomal translocation on species barriers suggests a mechanism for the generation of redundancy in the S. cerevisiae genome...
  18. pmc Sequencing and characterisation of rearrangements in three S. pastorianus strains reveals the presence of chimeric genes and gives evidence of breakpoint reuse
    Sarah K Hewitt
    Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
    PLoS ONE 9:e92203. 2014
    ..eubayanus recombination breakpoints are located within genic regions, generating chimeric genes. Furthermore we show evidence for the reuse of two breakpoints, located in HSP82 and KEM1, in strains of proposed independent origin...
  19. doi request reprint Non-coding RNAs in Saccharomyces cerevisiae: what is the function?
    Jian Wu
    Faculty of Life Sciences, University of Manchester, Manchester, UK
    Biochem Soc Trans 40:907-11. 2012
    ..Newly identified ncRNAs in this budding yeast, their functions in gene regulation and possible mechanisms of action are discussed...
  20. ncbi request reprint Probing (macro)molecular transport through cell walls
    Giona Kilcher
    School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester, United Kingdom M13 9PT
    Faraday Discuss 139:199-212; discussion 213-28, 419-20. 2008
    ..We also show that it is possible to reversibly alter the cell wall permeation properties without compromising the essence of its structure, by modifying the polarity/dielectric constant of the wall through solvent exchange...
  21. ncbi request reprint Development of novel guanidino-labelling derivatisation (GLaD) reagents for liquid chromatography/matrix-assisted laser desorption/ionisation analysis
    Francesco L Brancia
    Shimadzu Research Laboratory Europe, Manchester, UK
    Rapid Commun Mass Spectrom 21:3069-76. 2007
    ....
  22. doi request reprint New generation of loxP-mutated deletion cassettes for the genetic manipulation of yeast natural isolates
    Zorana Carter
    Faculty of Life Sciences, Manchester University, Manchester, UK
    Yeast 27:765-75. 2010
    ..cerevisiae strains, without the risk of incurring gross chromosomal rearrangements, and we showed an example of a fitness study of intraspecific hybrids deriving from parents with different adaptations to carbon-limited resources...