Marc de la Roche

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells
    Marc de la Roche
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    BMC Cancer 8:199. 2008
  2. doi request reprint Structural and functional properties of glycerol-3-phosphate dehydrogenase from a mammalian hibernator
    Marc de la Roche
    MRC Laboratory of Molecular Biology, Cambridge, UK
    Protein J 31:109-19. 2012
  3. pmc A role of Pygopus as an anti-repressor in facilitating Wnt-dependent transcription
    Juliusz Mieszczanek
    Medical Research Council Laboratory of Molecular Biology, Cambridge, CB2 0QH, United Kingdom
    Proc Natl Acad Sci U S A 105:19324-9. 2008
  4. pmc An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid
    Marc de la Roche
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    Nat Commun 3:680. 2012
  5. ncbi request reprint Wingless-independent association of Pygopus with dTCF target genes
    Marc de la Roche
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, United Kingdom
    Curr Biol 17:556-61. 2007

Collaborators

Detail Information

Publications5

  1. pmc The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells
    Marc de la Roche
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    BMC Cancer 8:199. 2008
    ..No loss-of-function data are available for BCL9...
  2. doi request reprint Structural and functional properties of glycerol-3-phosphate dehydrogenase from a mammalian hibernator
    Marc de la Roche
    MRC Laboratory of Molecular Biology, Cambridge, UK
    Protein J 31:109-19. 2012
    ..Structural and functional characteristics of G3PDH from the hibernating species would support enzyme function over a wide range of core body temperatures over cycles of torpor and arousal...
  3. pmc A role of Pygopus as an anti-repressor in facilitating Wnt-dependent transcription
    Juliusz Mieszczanek
    Medical Research Council Laboratory of Molecular Biology, Cambridge, CB2 0QH, United Kingdom
    Proc Natl Acad Sci U S A 105:19324-9. 2008
    ..This indicates an anti-repressor function of Pygo: we propose that Pygo predisposes Drosophila TCF target genes for rapid Wingless-induced transcription, or that it protects them against premature shut-down...
  4. pmc An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid
    Marc de la Roche
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    Nat Commun 3:680. 2012
    ....
  5. ncbi request reprint Wingless-independent association of Pygopus with dTCF target genes
    Marc de la Roche
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, United Kingdom
    Curr Biol 17:556-61. 2007
    ....