Helen R Dawe

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi request reprint Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells
    Helen R Dawe
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK
    J Cell Sci 120:7-15. 2007
  2. pmc The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules
    Helen R Dawe
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK
    BMC Biol 5:33. 2007
  3. ncbi request reprint The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis
    Helen R Dawe
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK
    J Cell Sci 118:5421-30. 2005
  4. pmc Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton
    Helen R Dawe
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    J Cell Sci 122:2716-26. 2009
  5. pmc Beyond 9+0: noncanonical axoneme structures characterize sensory cilia from protists to humans
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    FASEB J 24:3117-21. 2010
  6. doi request reprint The formation and positioning of cilia in Ciona intestinalis embryos in relation to the generation and evolution of chordate left-right asymmetry
    Helen Thompson
    Department of Zoology, University of Oxford, Oxford, UK
    Dev Biol 364:214-23. 2012
  7. ncbi request reprint The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation
    Helen R Dawe
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Hum Mol Genet 16:173-86. 2007
  8. doi request reprint Common themes in centriole and centrosome movements
    Sue Vaughan
    School of Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford, OX3 0BP, UK
    Trends Cell Biol 21:57-66. 2011

Detail Information

Publications8

  1. ncbi request reprint Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells
    Helen R Dawe
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK
    J Cell Sci 120:7-15. 2007
    ....
  2. pmc The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules
    Helen R Dawe
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK
    BMC Biol 5:33. 2007
    ..Mutations in hydin in hy3 mice cause lethal communicating hydrocephalus with early onset. Hydin was recently identified as an axonemal protein; however, its function is as yet unknown...
  3. ncbi request reprint The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis
    Helen R Dawe
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK
    J Cell Sci 118:5421-30. 2005
    ..Our results provide the first evidence for PACRG function within the axoneme, where we suggest that PACRG acts to maintain functional stability of the axonemal outer doublets of both motile and sensory cilia and flagella...
  4. pmc Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton
    Helen R Dawe
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    J Cell Sci 122:2716-26. 2009
    ....
  5. pmc Beyond 9+0: noncanonical axoneme structures characterize sensory cilia from protists to humans
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    FASEB J 24:3117-21. 2010
    ..We propose that the main function of the amastigote flagellum is to act as a sensory organelle with important functions in host-parasite interactions and signaling in the intracellular stage of the L. mexicana life cycle...
  6. doi request reprint The formation and positioning of cilia in Ciona intestinalis embryos in relation to the generation and evolution of chordate left-right asymmetry
    Helen Thompson
    Department of Zoology, University of Oxford, Oxford, UK
    Dev Biol 364:214-23. 2012
    ..intestinalis left-right asymmetry but that this would have to be in a sensory capacity, perhaps as mechanosensors as hypothesised in two-cilia physical models of vertebrate cilia-driven asymmetry...
  7. ncbi request reprint The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation
    Helen R Dawe
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Hum Mol Genet 16:173-86. 2007
    ..These results suggest that MKS proteins mediate a fundamental developmental stage of ciliary formation and epithelial morphogenesis...
  8. doi request reprint Common themes in centriole and centrosome movements
    Sue Vaughan
    School of Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford, OX3 0BP, UK
    Trends Cell Biol 21:57-66. 2011
    ..Knowledge of these common mechanisms can inform the study of centriole movements across biology...