Karen Davies

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. pmc Engaging the oldest old in research: lessons from the Newcastle 85+ study
    Karen Davies
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK
    BMC Geriatr 10:64. 2010
  2. pmc Prevalence of left ventricular dysfunction in a UK community sample of very old people: the Newcastle 85+ study
    Fahad Yousaf
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Heart 98:1418-23. 2012
  3. pmc Losing the ability in activities of daily living in the oldest old: a hierarchic disability scale from the Newcastle 85+ study
    Andrew Kingston
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 7:e31665. 2012
  4. pmc Capability and dependency in the Newcastle 85+ cohort study. Projections of future care needs
    Carol Jagger
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL UK
    BMC Geriatr 11:21. 2011
  5. pmc Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Neurobiol Aging 34:2889.e1-4. 2013
  6. doi request reprint The association between diagnosed glaucoma and cataract and cognitive performance in very old people: cross-sectional findings from the newcastle 85+ study
    Joanna M Jefferis
    Institute for Ageing and Health, Newcastle University, UK
    Ophthalmic Epidemiol 20:82-8. 2013
  7. pmc The impact of visual impairment on Mini-Mental State Examination Scores in the Newcastle 85+ study
    Joanna Mary Jefferis
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Age Ageing 41:565-8. 2012
  8. pmc The personal and health service impact of falls in 85 year olds: cross-sectional findings from the Newcastle 85+ cohort study
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 7:e33078. 2012
  9. pmc Reactive oxygen species production and mitochondrial dysfunction in white blood cells are not valid biomarkers of ageing in the very old
    Laura Wiley
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom
    PLoS ONE 9:e91005. 2014
  10. pmc The contribution of diseases to the male-female disability-survival paradox in the very old: results from the Newcastle 85+ study
    Andrew Kingston
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 9:e88016. 2014

Collaborators

Detail Information

Publications16

  1. pmc Engaging the oldest old in research: lessons from the Newcastle 85+ study
    Karen Davies
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK
    BMC Geriatr 10:64. 2010
    ..This paper describes the methods employed for the successful recruitment, retention and evaluation of this cohort...
  2. pmc Prevalence of left ventricular dysfunction in a UK community sample of very old people: the Newcastle 85+ study
    Fahad Yousaf
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Heart 98:1418-23. 2012
    ..We used domiciliary echocardiography to estimate the prevalence of LV systolic and diastolic dysfunction in 87-89 year olds and the proportion remaining undiagnosed...
  3. pmc Losing the ability in activities of daily living in the oldest old: a hierarchic disability scale from the Newcastle 85+ study
    Andrew Kingston
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 7:e31665. 2012
    ..To investigate the order in which 85 year olds develop difficulty in performing a wide range of daily activities covering basic personal care, household care and mobility...
  4. pmc Capability and dependency in the Newcastle 85+ cohort study. Projections of future care needs
    Carol Jagger
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL UK
    BMC Geriatr 11:21. 2011
    ..Little is known of the capabilities of the oldest old, the fastest growing age group in the population. We aimed to estimate capability and dependency in a cohort of 85 year olds and to project future demand for care...
  5. pmc Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Neurobiol Aging 34:2889.e1-4. 2013
    ..Conflicting data from different populations underscore our conclusion that there is currently no compelling link between inherited mtDNA variants and aging. ..
  6. doi request reprint The association between diagnosed glaucoma and cataract and cognitive performance in very old people: cross-sectional findings from the newcastle 85+ study
    Joanna M Jefferis
    Institute for Ageing and Health, Newcastle University, UK
    Ophthalmic Epidemiol 20:82-8. 2013
    ..Few studies have examined the relationship between cognition and cataract or glaucoma. We explored the association between cognition and cataract and glaucoma diagnoses in community-dwelling 85-year-olds...
  7. pmc The impact of visual impairment on Mini-Mental State Examination Scores in the Newcastle 85+ study
    Joanna Mary Jefferis
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Age Ageing 41:565-8. 2012
    ..This may be due to poor vision limiting performance on cognitive tasks specifically requiring vision, or an association between visual and neurodegenerative disorders...
  8. pmc The personal and health service impact of falls in 85 year olds: cross-sectional findings from the Newcastle 85+ cohort study
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 7:e33078. 2012
    ..We investigated the prevalence and impact of falls, and the overlap between falls, dizziness and blackouts, in a population-based sample of 85 year olds...
  9. pmc Reactive oxygen species production and mitochondrial dysfunction in white blood cells are not valid biomarkers of ageing in the very old
    Laura Wiley
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom
    PLoS ONE 9:e91005. 2014
    ..No associations were found between the measured parameters and age-related outcomes, including cognitive impairment, disability, co-morbidity and survival - questioning the validity of these parameters as candidate BoA in the very old. ..
  10. pmc The contribution of diseases to the male-female disability-survival paradox in the very old: results from the Newcastle 85+ study
    Andrew Kingston
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 9:e88016. 2014
    ..Less is known about the paradox in the very old. We examine sex differences in the presence and impact of disabling and fatal diseases accounting for the male-female disability-survival paradox in very late life...
  11. doi request reprint Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: cross-sectional findings from the Newcastle 85+ Study
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, United Kingdom
    Mech Ageing Dev 133:456-66. 2012
    ..Difficulties in operationalizing the Fried model, due to high levels of co-morbidity, limit its utility in the very old...
  12. ncbi request reprint Acquisition of aberrant DNA methylation is associated with frailty in the very old: findings from the Newcastle 85+ Study
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK
    Biogerontology 15:317-28. 2014
    ..47 (95 % CI 0.26-0.85); n = 321, p = 0.013]. Overall this study suggests a potential role for age-related changes in CpG island methylation in the development of frailty. ..
  13. doi request reprint Assessment of sleep and circadian rhythm disorders in the very old: the Newcastle 85+ Cohort Study
    Kirstie N Anderson
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Age Ageing 43:57-63. 2014
    ..to examine the association between subjective and objective measures of sleep and wake and other health parameters in a cohort of the very old...
  14. doi request reprint Assessment of a large panel of candidate biomarkers of ageing in the Newcastle 85+ study
    Carmen Martin-Ruiz
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Mech Ageing Dev 132:496-502. 2011
    ..As future data accrues on health outcomes within the cohort, it will become possible also to evaluate the predictive value of these and others of the candidate biomarkers...
  15. pmc Health and disease in 85 year olds: baseline findings from the Newcastle 85+ cohort study
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL
    BMJ 339:b4904. 2009
    ....
  16. doi request reprint Nutrition in advanced age: dietary assessment in the Newcastle 85+ study
    A J Adamson
    Human Nutrition Research Centre, Newcastle University, Newcastle upon Tyne, UK
    Eur J Clin Nutr 63:S6-18. 2009
    ..This paper describes a comparison of two different methods of dietary assessment within the Newcastle 85+ Study; a UK cohort study of health and ageing in the oldest old...