Research Topics
| Barry R DaviesSummaryAffiliation: University of Newcastle Country: UK Publications
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Detail Information
Publications
Development of hyperplasias, preneoplasias, and mammary tumors in MMTV-c-erbB-2 and MMTV-TGFalpha transgenic ratsB R Davies
Department of Surgery, School of Surgical Sciences, The Medical School, University of Newcastle upon Tyne, Cambridge, United Kingdom
Am J Pathol 155:303-14. 1999..These transgenic rat models confirm the conclusions reached in transgenic mice that overexpression of the c-erbB-2 and TGFalpha genes predisposes the mammary gland to stochastic tumor development...
Expression of S100A4 protein is associated with metastasis and reduced survival in human bladder cancerBarry R Davies
Department of Surgery, The Medical School, University of Newcastle, Newcastle upon Tyne NE2 4HH, UK
J Pathol 196:292-9. 2002..0001). It is concluded that S100A4 expression may play an important role in bladder cancer and may identify a subgroup of patients at increased risk of metastasis who should be considered for adjuvant systemic therapy...
Gene products involved in metastasis of bladder cancerB R Davies
Northern Institute for Cancer Research, and School of Surgical and Reproductive Sciences, The Medical School, University of Newcastle, Newcastle upon Tyne, UK
Histol Histopathol 18:969-80. 2003....
Immortalisation of human ovarian surface epithelium with telomerase and temperature-sensitive SV40 large T antigenBarry R Davies
Department of Surgery, University of Newcastle, Newcastle upon Tyne, NE2 4HH, UK
Exp Cell Res 288:390-402. 2003..OSE-C2 cells may be useful in studying the physiology and differentiation of human OSE cells and provide insight into the poorly understood earliest stages of epithelial ovarian cancer...
Ligands to FGF receptor 2-IIIb induce proliferation, motility, protection from cell death and cytoskeletal rearrangements in epithelial ovarian cancer cell linesIslay A Steele
Northern Institute for Cancer Research and School of Surgical and Reproductive Sciences, Faculty of Medical Sciences, University of Newcastle, Newcastle-upon-Tyne, UK
Growth Factors 24:45-53. 2006..It is suggested that ligands to FGF receptor 2-IIIb affect a range of phenotypes important in the neoplastic growth of EOCs...
Transfection of S100A4 produces metastatic variants of an orthotopic model of bladder cancerDiana Levett
Department of Surgery, The Medical School, University of Newcastle-upon-Tyne, Newcastle NE2 4HH, United Kingdom
Am J Pathol 160:693-700. 2002....
High-mobility group protein 1(Y): metastasis-associated or metastasis-inducing?Alice Evans
School of Surgical and Reproductive Sciences and Northern Institute for Cancer Research, Faculty of Medical Sciences, University of Newcastle upon Tyne, United Kingdom
J Surg Oncol 88:86-99. 2004..This may represent a potential therapeutic target for patients. The following review summarizes and critically appraises the evidence for the role of HMG-1(Y) in metastasis...
Behavioural assessment of the effects of tumour growth in rats and the influence of the analgesics carprofen and meloxicamJohn V Roughan
Comparative Biology Centre, The Medical School, University of Newcastle, Newcastle upon Tyne, NE2 4HH, UK
Lab Anim 38:286-96. 2004..More intensive behaviour monitoring may help to develop a suitable technique for detecting the onset of, and assess the severity of pain that may occur during tumour development...
Mcm-2 and Ki-67 have limited potential in preoperative diagnosis of thyroid malignancyPallavi Mehrotra
School of Surgical and Reproductive Sciences, Department of Cellular Pathology, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom
Laryngoscope 116:1434-8. 2006..CONCLUSION: Neither Mcm-2 or Ki-67 can currently be reliably applied as preoperative markers to distinguish benign from malignant thyroid lesions...
Celecoxib has potent antitumour effects as a single agent and in combination with BCG immunotherapy in a model of urothelial cell carcinomaSimon J Dovedi
Department of Surgery Northern Institute for Cancer Research, Medical School, University of Newcastle, Newcastle upon Tyne, United Kingdom
Eur Urol 54:621-30. 2008....
Evaluation of the therapeutic potential of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in preclinical models of bladder cancerJose L Dominguez-Escrig
Northern Institute for Cancer Research, School of Surgical and Reproductive Sciences, Faculty of Medical Sciences, University of Newcastle, Newcastle-upon-Tyne, United Kingdom
Clin Cancer Res 10:4874-84. 2004..It is likely that optimized therapy approaches will require an accurate "molecular" diagnosis allowing effective, selective, tailored therapeutic strategies to be designed...
Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancerArezoo Astanehe
Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, Canada
J Cell Sci 121:664-74. 2008....
