Hazel M Davey

Summary

Affiliation: University of Wales
Country: UK

Publications

  1. ncbi request reprint Using flow cytometry to quantify microbial heterogeneity
    Hazel M Davey
    Institute of Biological Sciences, University of Wales, Aberystwyth, Ceredigion, SY23 3DD Wales, UK
    Curr Issues Mol Biol 5:9-15. 2003
  2. doi request reprint Genome-wide analysis of longevity in nutrient-deprived Saccharomyces cerevisiae reveals importance of recycling in maintaining cell viability
    Hazel M Davey
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, UK
    Environ Microbiol 14:1249-60. 2012
  3. doi request reprint Red but not dead? Membranes of stressed Saccharomyces cerevisiae are permeable to propidium iodide
    H M Davey
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Penglais, Aberystwyth, UK
    Environ Microbiol 13:163-71. 2011
  4. pmc Life, death, and in-between: meanings and methods in microbiology
    Hazel M Davey
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, Wales, United Kingdom
    Appl Environ Microbiol 77:5571-6. 2011
  5. ncbi request reprint Fluorescent brighteners: novel stains for the flow cytometric analysis of microorganisms
    H M Davey
    Institute of Biological Sciences, University of Wales, Aberystwyth, Dyfed, United Kingdom
    Cytometry 28:311-5. 1997
  6. ncbi request reprint Flow cytometric techniques for the detection of microorganisms
    Hazel M Davey
    Institute of Biological Sciences, University of Wales, Aberystwyth, Ceredigion, SY23 3DD Wales, UK
    Methods Cell Sci 24:91-7. 2002
  7. ncbi request reprint Variable selection and multivariate methods for the identification of microorganisms by flow cytometry
    H M Davey
    Institute of Biological Sciences, University of Wales, Aberystwyth, Ceredigion, United Kingdom
    Cytometry 35:162-8. 1999
  8. doi request reprint Multivariate data analysis methods for the interpretation of microbial flow cytometric data
    Hazel M Davey
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Penglais, Aberystwyth, SY23 3DD, UK
    Adv Biochem Eng Biotechnol 124:183-209. 2011
  9. pmc Discrimination of modes of action of antifungal substances by use of metabolic footprinting
    Jess Allen
    Department of Biological Sciences, University of Wales, Aberystwyth, UK
    Appl Environ Microbiol 70:6157-65. 2004
  10. ncbi request reprint High-throughput classification of yeast mutants for functional genomics using metabolic footprinting
    Jess Allen
    Institute of Biological Sciences, Cledwyn Building, University of Wales, Aberystwyth, Aberystwyth SY23 3DD, UK
    Nat Biotechnol 21:692-6. 2003

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Using flow cytometry to quantify microbial heterogeneity
    Hazel M Davey
    Institute of Biological Sciences, University of Wales, Aberystwyth, Ceredigion, SY23 3DD Wales, UK
    Curr Issues Mol Biol 5:9-15. 2003
    ....
  2. doi request reprint Genome-wide analysis of longevity in nutrient-deprived Saccharomyces cerevisiae reveals importance of recycling in maintaining cell viability
    Hazel M Davey
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, UK
    Environ Microbiol 14:1249-60. 2012
    ..These methods thus provide a screen to identifying other genes and pathways that have a role in maintaining cell viability...
  3. doi request reprint Red but not dead? Membranes of stressed Saccharomyces cerevisiae are permeable to propidium iodide
    H M Davey
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Penglais, Aberystwyth, UK
    Environ Microbiol 13:163-71. 2011
    ..We discuss these findings in the context of the potential for such environmental stress-induced, transient membrane permeability to have evolutionary implications via the facilitation of horizontal gene transfer...
  4. pmc Life, death, and in-between: meanings and methods in microbiology
    Hazel M Davey
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, Wales, United Kingdom
    Appl Environ Microbiol 77:5571-6. 2011
    ..This review explores the meaning of microbial viability and offers guidance in the selection and interpretation of viability testing methods...
  5. ncbi request reprint Fluorescent brighteners: novel stains for the flow cytometric analysis of microorganisms
    H M Davey
    Institute of Biological Sciences, University of Wales, Aberystwyth, Dyfed, United Kingdom
    Cytometry 28:311-5. 1997
    ..Under favourable conditions, Tinopal CBS-X may be used to discriminate among organisms, a fact that may be useful when screening for a target microorganism against a high biological background...
  6. ncbi request reprint Flow cytometric techniques for the detection of microorganisms
    Hazel M Davey
    Institute of Biological Sciences, University of Wales, Aberystwyth, Ceredigion, SY23 3DD Wales, UK
    Methods Cell Sci 24:91-7. 2002
    ..This review seeks to highlight the role of the flow cytometer in the detection of microbial cells...
  7. ncbi request reprint Variable selection and multivariate methods for the identification of microorganisms by flow cytometry
    H M Davey
    Institute of Biological Sciences, University of Wales, Aberystwyth, Ceredigion, United Kingdom
    Cytometry 35:162-8. 1999
    ..g., using unsupervised methods such as principal components analysis) so that fewer graphs need to be examined, or to use supervised multivariate data analysis methods to give a prediction of the identity of the analyzed particles...
  8. doi request reprint Multivariate data analysis methods for the interpretation of microbial flow cytometric data
    Hazel M Davey
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Penglais, Aberystwyth, SY23 3DD, UK
    Adv Biochem Eng Biotechnol 124:183-209. 2011
    ..The data analysis methods described here are equally applicable to flow cytometric applications with other cell types...
  9. pmc Discrimination of modes of action of antifungal substances by use of metabolic footprinting
    Jess Allen
    Department of Biological Sciences, University of Wales, Aberystwyth, UK
    Appl Environ Microbiol 70:6157-65. 2004
    ..Metabolic footprinting thus represents a rapid, convenient, and information-rich method for classifying the modes of action of antifungal substances...
  10. ncbi request reprint High-throughput classification of yeast mutants for functional genomics using metabolic footprinting
    Jess Allen
    Institute of Biological Sciences, Cledwyn Building, University of Wales, Aberystwyth, Aberystwyth SY23 3DD, UK
    Nat Biotechnol 21:692-6. 2003
    ..By using appropriate clustering and machine learning techniques, the latter based on genetic programming, we show that metabolic footprinting is an effective method to classify 'unknown' mutants by genetic defect...
  11. doi request reprint Predatory activity of Myxococcus xanthus outer-membrane vesicles and properties of their hydrolase cargo
    Alun G L Evans
    Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, Ceredigion SY23 3DD, UK
    Microbiology 158:2742-52. 2012
    ..coli outer membrane. M. xanthus secretes GAPDH, which could potentially modulate the fusion of co-secreted OMVs with prey organisms in nature, enhancing their predatory activity...
  12. doi request reprint Estimation of microbial viability using flow cytometry
    Hazel M Davey
    University of Wales, Aberystwyth, United Kingdom
    Curr Protoc Cytom . 2004
    ..What is clear is that each assay must be carefully validated with the particular microorganism of interest before being applied in any research, clinical, or service form...
  13. pmc A directed evolution strategy for optimized export of recombinant proteins reveals critical determinants for preprotein discharge
    Mustak A Kaderbhai
    Institute of Biological Sciences, Cledwyn Building, University of Wales, Aberystwyth, Ceredigion, SY23 3DD, UK
    Protein Sci 13:2458-69. 2004
    ..coli. We conclude that the directed evolutionary approach will find ready application in engineering recombinant proteins for their efficient secretion via the sec export pathway in E. coli...
  14. ncbi request reprint Detection of mycoplasmas in goat milk by flow cytometry
    Patricia Assunçao
    Unidad de Epidemiologia y Medicina Preventiva, Facultad de Veterinaria, Universidad de Las Palmas de Gran Canaria, Arucas, Spain
    Cytometry A 71:1034-8. 2007
    ..This is an important first step in developing a robust, routine flow cytometric method for the detection of mycoplasmas in milk samples...
  15. ncbi request reprint Flow cytometric method for the assessment of the minimal inhibitory concentrations of antibacterial agents to Mycoplasma agalactiae
    Patricia Assunçao
    Unidad de Epidemiologia y Medicina Preventiva, Facultad de Veterinaria, Universidad de Las Palmas de Gran Canaria, Arucas, Spain
    Cytometry A 69:1071-6. 2006
    ..The method presented makes identification of resistant populations of M. agalactiae possible and, unlike the traditional method, allows the effect of each antibacterial agent to be determined in real-time at the single-cell level...
  16. ncbi request reprint Metabolic footprinting and systems biology: the medium is the message
    Douglas B Kell
    School of Chemistry, University of Manchester, Faraday Building, PO Box 88, Sackville Street, Manchester M60 1QD, UK
    Nat Rev Microbiol 3:557-65. 2005
    ..Here, we review the principles, experimental approaches and scientific outcomes that have been obtained with this useful and convenient strategy...
  17. pmc Flow cytometric determination of the effects of antibacterial agents on Mycoplasma agalactiae, Mycoplasma putrefaciens, Mycoplasma capricolum subsp. capricolum, and Mycoplasma mycoides subsp. mycoides large colony type
    Patricia Assunçao
    Unidad de Epidemiologia y Medicina Preventiva, Facultad de Veterinaria, Universidad de Las Palmas de Gran Canaria, Arucas, Las Palmas, Spain
    Antimicrob Agents Chemother 50:2845-9. 2006
    ..Inhibition of mycoplasma growth could be detected by as early as 3 h after the start of treatment. The strongest effect was observed with enrofloxacin- and ciprofloxacin-treated cells...