Sarah Darby

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. doi request reprint Risk of ischemic heart disease in women after radiotherapy for breast cancer
    Sarah C Darby
    Clinical Trial Service Unit, University of Oxford, Oxford, United Kingdom
    N Engl J Med 368:987-98. 2013
  2. pmc Increased cardiovascular mortality more than fifteen years after radiotherapy for breast cancer: a population-based study
    Rahul Roychoudhuri
    King s College London, Thames Cancer Registry, 1st Floor Capital House, 42 Weston Street, London SE1 3QD, UK
    BMC Cancer 7:9. 2007
  3. ncbi request reprint Health effects of residential radon: a European perspective at the end of 2002
    S C Darby
    University of Oxford, Clinical Trial Service Unit and Epidemiological Studies Unit, Harkness Building, Radcliffe Infirmary, Oxford OX2 6HE, UK
    Radiat Prot Dosimetry 104:321-9. 2003
  4. pmc Mortality from cardiovascular disease more than 10 years after radiotherapy for breast cancer: nationwide cohort study of 90 000 Swedish women
    Sarah Darby
    Clinical Trial Service Unit and Epidemiological Studies Unit, Radcliffe Infirmary, Oxford OX2 6HE
    BMJ 326:256-7. 2003
  5. ncbi request reprint Radon: a likely carcinogen at all exposures
    S Darby
    Clinical Trial Service Unit, University of Oxford, UK
    Ann Oncol 12:1341-51. 2001
  6. ncbi request reprint Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: prospective cohort study of about 300,000 women in US SEER cancer registries
    Sarah C Darby
    Clinical Trial Service Unit, University of Oxford, Oxford, UK
    Lancet Oncol 6:557-65. 2005
  7. ncbi request reprint Residential radon and lung cancer--detailed results of a collaborative analysis of individual data on 7148 persons with lung cancer and 14,208 persons without lung cancer from 13 epidemiologic studies in Europe
    Sarah Darby
    Clinical Trial Service Unit, Richard Doll Building, University of Oxford, Oxford, United Kingdom
    Scand J Work Environ Health 32:1-83. 2006
  8. pmc Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies
    S Darby
    Clinical Trials Service Unit and Epidemiological Studies Unit, Radcliffe Infirmary, Oxford OX2 6HE
    BMJ 330:223. 2005
  9. ncbi request reprint Residential radon, smoking and lung cancer
    Sarah Darby
    University of Oxford, Clinical Trial Service Unit, Harkness Building, Radcliffe Infirmary, OX2 6HE, United Kingdom
    Radiat Res 163:696. 2005
  10. pmc Risk of lung cancer associated with residential radon exposure in south-west England: a case-control study
    S Darby
    ICRF Cancer Epidemiology Unit, University of Oxford, Radcliffe Infirmary, UK
    Br J Cancer 78:394-408. 1998

Detail Information

Publications23

  1. doi request reprint Risk of ischemic heart disease in women after radiotherapy for breast cancer
    Sarah C Darby
    Clinical Trial Service Unit, University of Oxford, Oxford, United Kingdom
    N Engl J Med 368:987-98. 2013
    ..Radiotherapy for breast cancer often involves some incidental exposure of the heart to ionizing radiation. The effect of this exposure on the subsequent risk of ischemic heart disease is uncertain...
  2. pmc Increased cardiovascular mortality more than fifteen years after radiotherapy for breast cancer: a population-based study
    Rahul Roychoudhuri
    King s College London, Thames Cancer Registry, 1st Floor Capital House, 42 Weston Street, London SE1 3QD, UK
    BMC Cancer 7:9. 2007
    ..It has been proposed that this difference might result in greater cardiovascular mortality following irradiation of the left breast when compared with the right...
  3. ncbi request reprint Health effects of residential radon: a European perspective at the end of 2002
    S C Darby
    University of Oxford, Clinical Trial Service Unit and Epidemiological Studies Unit, Harkness Building, Radcliffe Infirmary, Oxford OX2 6HE, UK
    Radiat Prot Dosimetry 104:321-9. 2003
    ..To achieve this, a European Collaborative Group on Residential Radon and Lung Cancer was initiated and its findings should be published in 2004...
  4. pmc Mortality from cardiovascular disease more than 10 years after radiotherapy for breast cancer: nationwide cohort study of 90 000 Swedish women
    Sarah Darby
    Clinical Trial Service Unit and Epidemiological Studies Unit, Radcliffe Infirmary, Oxford OX2 6HE
    BMJ 326:256-7. 2003
  5. ncbi request reprint Radon: a likely carcinogen at all exposures
    S Darby
    Clinical Trial Service Unit, University of Oxford, UK
    Ann Oncol 12:1341-51. 2001
    ..Radon is a well-established lung carcinogen that has been extensively studied. Very high concentrations can occur in some underground mines. Concentrations also tend to build up in homes...
  6. ncbi request reprint Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: prospective cohort study of about 300,000 women in US SEER cancer registries
    Sarah C Darby
    Clinical Trial Service Unit, University of Oxford, Oxford, UK
    Lancet Oncol 6:557-65. 2005
    ..This study aimed to assess the hazards in the general US population from routine cancer-registry and death-certificate data...
  7. ncbi request reprint Residential radon and lung cancer--detailed results of a collaborative analysis of individual data on 7148 persons with lung cancer and 14,208 persons without lung cancer from 13 epidemiologic studies in Europe
    Sarah Darby
    Clinical Trial Service Unit, Richard Doll Building, University of Oxford, Oxford, United Kingdom
    Scand J Work Environ Health 32:1-83. 2006
    ..Therefore data from all 13 European studies of residential radon and lung cancer satisfying certain prespecified criteria have been brought together and analyzed...
  8. pmc Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies
    S Darby
    Clinical Trials Service Unit and Epidemiological Studies Unit, Radcliffe Infirmary, Oxford OX2 6HE
    BMJ 330:223. 2005
    ..To determine the risk of lung cancer associated with exposure at home to the radioactive disintegration products of naturally occurring radon gas...
  9. ncbi request reprint Residential radon, smoking and lung cancer
    Sarah Darby
    University of Oxford, Clinical Trial Service Unit, Harkness Building, Radcliffe Infirmary, OX2 6HE, United Kingdom
    Radiat Res 163:696. 2005
  10. pmc Risk of lung cancer associated with residential radon exposure in south-west England: a case-control study
    S Darby
    ICRF Cancer Epidemiology Unit, University of Oxford, Radcliffe Infirmary, UK
    Br J Cancer 78:394-408. 1998
    ..The combined evidence suggests that the risk of lung cancer associated with residential radon exposure is about the size that has been postulated on the basis of the studies of miners exposed to radon...
  11. pmc Lung cancer deaths from indoor radon and the cost effectiveness and potential of policies to reduce them
    Alastair Gray
    Health Economics Research Centre, Department of Public Health, University of Oxford, Oxford OX3 7LF
    BMJ 338:a3110. 2009
    ..To determine the number of deaths from lung cancer related to radon in the home and to explore the cost effectiveness of alternative policies to control indoor radon and their potential to reduce lung cancer mortality...
  12. doi request reprint Demonstration of fluid channels in human dura and their relationship to age and intradural bleeding
    W Squier
    Department of Neuropathology, West Wing, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Childs Nerv Syst 25:925-31. 2009
    ..This paper aims to make a systematic study of human dura to establish the presence of fluid transport channels and their relationship to age...
  13. pmc Diet, smoking and lung cancer: a case-control study of 1000 cases and 1500 controls in South-West England
    S Darby
    ICRF MRC BHF Clinical Trial Service Unit and Epidemiological Studies Unit, Radcliffe Infirmary, Harkness Building, Oxford, OX2 6HE, UK
    Br J Cancer 84:728-35. 2001
    ..We conclude that there is at least one as yet unidentified factor that is causally related to lung cancer risk and of considerable importance in terms of attributable risk in this population...
  14. pmc N-acetyltransferase 2 and bladder cancer: an overview and consideration of the evidence for gene-environment interaction
    J Green
    Imperial Cancer Research Fund Cancer Epidemiology Unit, University of Oxford, Radcliffe Infirmary, UK
    Br J Cancer 83:412-7. 2000
    ..Even if estimates of the effect of NAT2 from published data are correct, studies with around 3000-5000 cases will be needed to confirm them...
  15. ncbi request reprint Risk of cancer from diagnostic X-rays: estimates for the UK and 14 other countries
    Amy Berrington de Gonzalez
    Cancer Research UK Epidemiology Unit, University of Oxford, Radcliffe Infirmary, Oxford, UK
    Lancet 363:345-51. 2004
    ..Our aim was to estimate the extent of this risk on the basis of the annual number of diagnostic X-rays undertaken in the UK and in 14 other developed countries...
  16. pmc Mortality associated with oral contraceptive use: 25 year follow up of cohort of 46 000 women from Royal College of General Practitioners' oral contraception study
    V Beral
    Imperial Cancer Research Fund, Cancer Epidemiology Unit, Radcliffe Infirmary, Oxford OX2 6HE
    BMJ 318:96-100. 1999
    ..To describe the long term effects of the use of oral contraceptives on mortality...
  17. doi request reprint Commentary: A dose-response relationship for radiation-induced heart disease--current issues and future prospects
    Paul McGale
    Clinical Trial Service Unit, Richard Doll Building, University of Oxford, Old Road Campus, Roosevelt Drive, Oxford OX3 7LF, UK
    Int J Epidemiol 37:518-23. 2008
  18. doi request reprint Cardiac dose from tangential breast cancer radiotherapy in the year 2006
    Carolyn W Taylor
    Clinical Trial Service Unit, Oxford, United Kingdom
    Int J Radiat Oncol Biol Phys 72:501-7. 2008
    ..To quantify the radiation doses received by the heart and coronary arteries from contemporary tangential breast or chest wall radiotherapy...
  19. ncbi request reprint Cardiac exposures in breast cancer radiotherapy: 1950s-1990s
    Carolyn W Taylor
    Clinical Trial Service Unit, Oxford University, Oxford, United Kingdom
    Int J Radiat Oncol Biol Phys 69:1484-95. 2007
    ..To estimate the doses to the heart and coronary arteries from common breast cancer radiotherapy (RT) regimens used worldwide from the 1950s to the 1990s...
  20. ncbi request reprint Low doses of ionizing radiation and circulatory diseases: a systematic review of the published epidemiological evidence
    Paul McGale
    Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, United Kingdom
    Radiat Res 163:247-57. 2005
    ..Further evidence is needed to characterize the possible risk...
  21. ncbi request reprint Secondhand smoke exposure in adulthood and risk of lung cancer among never smokers: a pooled analysis of two large studies
    Paul Brennan
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 109:125-31. 2004
    ..Clear dose-response relationships consistent with a causal association were observed between exposure to secondhand smoke from spousal, workplace and social sources and the development of lung cancer among never smokers...
  22. ncbi request reprint Estimates of the cancer burden in Europe from radioactive fallout from the Chernobyl accident
    Elisabeth Cardis
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 119:1224-35. 2006
    ....
  23. ncbi request reprint The impact of HIV on mortality rates in the complete UK haemophilia population
    Sarah C Darby
    AIDS 18:525-33. 2004
    ..To estimate the effect of HIV-1 infection on subsequent mortality in a complete population...