Affiliation: University of Oxford
- Risk of ischemic heart disease in women after radiotherapy for breast cancerSarah C Darby
Clinical Trial Service Unit, University of Oxford, Oxford, United Kingdom
N Engl J Med 368:987-98. 2013..Radiotherapy for breast cancer often involves some incidental exposure of the heart to ionizing radiation. The effect of this exposure on the subsequent risk of ischemic heart disease is uncertain...
- Increased cardiovascular mortality more than fifteen years after radiotherapy for breast cancer: a population-based studyRahul Roychoudhuri
King s College London, Thames Cancer Registry, 1st Floor Capital House, 42 Weston Street, London SE1 3QD, UK
BMC Cancer 7:9. 2007..It has been proposed that this difference might result in greater cardiovascular mortality following irradiation of the left breast when compared with the right...
- Health effects of residential radon: a European perspective at the end of 2002S C Darby
University of Oxford, Clinical Trial Service Unit and Epidemiological Studies Unit, Harkness Building, Radcliffe Infirmary, Oxford OX2 6HE, UK
Radiat Prot Dosimetry 104:321-9. 2003..To achieve this, a European Collaborative Group on Residential Radon and Lung Cancer was initiated and its findings should be published in 2004...
- Mortality from cardiovascular disease more than 10 years after radiotherapy for breast cancer: nationwide cohort study of 90 000 Swedish womenSarah Darby
Clinical Trial Service Unit and Epidemiological Studies Unit, Radcliffe Infirmary, Oxford OX2 6HE
BMJ 326:256-7. 2003
- Radon: a likely carcinogen at all exposuresS Darby
Clinical Trial Service Unit, University of Oxford, UK
Ann Oncol 12:1341-51. 2001..Radon is a well-established lung carcinogen that has been extensively studied. Very high concentrations can occur in some underground mines. Concentrations also tend to build up in homes...
- Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: prospective cohort study of about 300,000 women in US SEER cancer registriesSarah C Darby
Clinical Trial Service Unit, University of Oxford, Oxford, UK
Lancet Oncol 6:557-65. 2005..This study aimed to assess the hazards in the general US population from routine cancer-registry and death-certificate data...
- Residential radon and lung cancer--detailed results of a collaborative analysis of individual data on 7148 persons with lung cancer and 14,208 persons without lung cancer from 13 epidemiologic studies in EuropeSarah Darby
Clinical Trial Service Unit, Richard Doll Building, University of Oxford, Oxford, United Kingdom
Scand J Work Environ Health 32:1-83. 2006..Therefore data from all 13 European studies of residential radon and lung cancer satisfying certain prespecified criteria have been brought together and analyzed...
- Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studiesS Darby
Clinical Trials Service Unit and Epidemiological Studies Unit, Radcliffe Infirmary, Oxford OX2 6HE
BMJ 330:223. 2005..To determine the risk of lung cancer associated with exposure at home to the radioactive disintegration products of naturally occurring radon gas...
- Residential radon, smoking and lung cancerSarah Darby
University of Oxford, Clinical Trial Service Unit, Harkness Building, Radcliffe Infirmary, OX2 6HE, United Kingdom
Radiat Res 163:696. 2005
- Risk of lung cancer associated with residential radon exposure in south-west England: a case-control studyS Darby
ICRF Cancer Epidemiology Unit, University of Oxford, Radcliffe Infirmary, UK
Br J Cancer 78:394-408. 1998..The combined evidence suggests that the risk of lung cancer associated with residential radon exposure is about the size that has been postulated on the basis of the studies of miners exposed to radon...
- Lung cancer deaths from indoor radon and the cost effectiveness and potential of policies to reduce themAlastair Gray
Health Economics Research Centre, Department of Public Health, University of Oxford, Oxford OX3 7LF
BMJ 338:a3110. 2009..To determine the number of deaths from lung cancer related to radon in the home and to explore the cost effectiveness of alternative policies to control indoor radon and their potential to reduce lung cancer mortality...
- Demonstration of fluid channels in human dura and their relationship to age and intradural bleedingW Squier
Department of Neuropathology, West Wing, John Radcliffe Hospital, Oxford OX3 9DU, UK
Childs Nerv Syst 25:925-31. 2009..This paper aims to make a systematic study of human dura to establish the presence of fluid transport channels and their relationship to age...
- Diet, smoking and lung cancer: a case-control study of 1000 cases and 1500 controls in South-West EnglandS Darby
ICRF MRC BHF Clinical Trial Service Unit and Epidemiological Studies Unit, Radcliffe Infirmary, Harkness Building, Oxford, OX2 6HE, UK
Br J Cancer 84:728-35. 2001..We conclude that there is at least one as yet unidentified factor that is causally related to lung cancer risk and of considerable importance in terms of attributable risk in this population...
- N-acetyltransferase 2 and bladder cancer: an overview and consideration of the evidence for gene-environment interactionJ Green
Imperial Cancer Research Fund Cancer Epidemiology Unit, University of Oxford, Radcliffe Infirmary, UK
Br J Cancer 83:412-7. 2000..Even if estimates of the effect of NAT2 from published data are correct, studies with around 3000-5000 cases will be needed to confirm them...
- Risk of cancer from diagnostic X-rays: estimates for the UK and 14 other countriesAmy Berrington de Gonzalez
Cancer Research UK Epidemiology Unit, University of Oxford, Radcliffe Infirmary, Oxford, UK
Lancet 363:345-51. 2004..Our aim was to estimate the extent of this risk on the basis of the annual number of diagnostic X-rays undertaken in the UK and in 14 other developed countries...
- Mortality associated with oral contraceptive use: 25 year follow up of cohort of 46 000 women from Royal College of General Practitioners' oral contraception studyV Beral
Imperial Cancer Research Fund, Cancer Epidemiology Unit, Radcliffe Infirmary, Oxford OX2 6HE
BMJ 318:96-100. 1999..To describe the long term effects of the use of oral contraceptives on mortality...
- Commentary: A dose-response relationship for radiation-induced heart disease--current issues and future prospectsPaul McGale
Clinical Trial Service Unit, Richard Doll Building, University of Oxford, Old Road Campus, Roosevelt Drive, Oxford OX3 7LF, UK
Int J Epidemiol 37:518-23. 2008
- Cardiac dose from tangential breast cancer radiotherapy in the year 2006Carolyn W Taylor
Clinical Trial Service Unit, Oxford, United Kingdom
Int J Radiat Oncol Biol Phys 72:501-7. 2008..To quantify the radiation doses received by the heart and coronary arteries from contemporary tangential breast or chest wall radiotherapy...
- Cardiac exposures in breast cancer radiotherapy: 1950s-1990sCarolyn W Taylor
Clinical Trial Service Unit, Oxford University, Oxford, United Kingdom
Int J Radiat Oncol Biol Phys 69:1484-95. 2007..To estimate the doses to the heart and coronary arteries from common breast cancer radiotherapy (RT) regimens used worldwide from the 1950s to the 1990s...
- Low doses of ionizing radiation and circulatory diseases: a systematic review of the published epidemiological evidencePaul McGale
Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, United Kingdom
Radiat Res 163:247-57. 2005..Further evidence is needed to characterize the possible risk...
- Secondhand smoke exposure in adulthood and risk of lung cancer among never smokers: a pooled analysis of two large studiesPaul Brennan
International Agency for Research on Cancer, Lyon, France
Int J Cancer 109:125-31. 2004..Clear dose-response relationships consistent with a causal association were observed between exposure to secondhand smoke from spousal, workplace and social sources and the development of lung cancer among never smokers...
- Estimates of the cancer burden in Europe from radioactive fallout from the Chernobyl accidentElisabeth Cardis
International Agency for Research on Cancer, Lyon, France
Int J Cancer 119:1224-35. 2006....
- The impact of HIV on mortality rates in the complete UK haemophilia populationSarah C Darby
AIDS 18:525-33. 2004..To estimate the effect of HIV-1 infection on subsequent mortality in a complete population...