Russell C Dale

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi Post-streptococcal autoimmune disorders of the central nervous system
    Russell C Dale
    Neurosciences Unit, Great Ormond Street Hospital NHS Trust, London, UK
    Dev Med Child Neurol 47:785-91. 2005
  2. ncbi Encephalitis lethargica syndrome: 20 new cases and evidence of basal ganglia autoimmunity
    Russell C Dale
    Neurosciences Unit, Great Ormond Street Hospital and Institute of Child Health, and Department of Neuroinflammation, Institute of Neurology, University College London, UK
    Brain 127:21-33. 2004
  3. ncbi Acute disseminated encephalomyelitis
    Russell C Dale
    Neurosciences Unit, Institute of Child Health and Great Ormond Street Hospital NHS Trust, and the Department of Neuroinflammation, Institute of Neurology, London, United Kingdom
    Semin Pediatr Infect Dis 14:90-5. 2003
  4. ncbi CSF and serum immune parameters in Sydenham's chorea: evidence of an autoimmune syndrome?
    Andrew J Church
    Neuroimmunology Unit, Neuroinflammation Department, Institute of Neurology, Room 917, Queen Square, London WC1N 3BG, UK
    J Neuroimmunol 136:149-53. 2003
  5. ncbi Striatal encephalitis after varicella zoster infection complicated by Tourettism
    Russell C Dale
    Neurosciences Unit, Institute of Child Health and Great Ormond Street Hospital NHS Trust, London, United Kingdom
    Mov Disord 18:1554-6. 2003
  6. ncbi Quantitative demonstration of intrathecal synthesis of high affinity immunoglobulin G in herpes simplex encephalitis using affinity-mediated immunoblotting
    Miles D Chapman
    Department of Neuroimmunology, Institute of Neurology, Queen Square, London, WC1N 3BG, UK
    J Neuroimmunol 185:130-5. 2007
  7. ncbi Childhood opsoclonus myoclonus
    Russell C Dale
    Neurosciences Unit, Institute of Child Health, University College, London, UK
    Lancet Neurol 2:270. 2003
  8. ncbi Post-streptococcal autoimmune dystonia with isolated bilateral striatal necrosis
    Russell C Dale
    Neurosciences Unit, Institute of Child Health, London, UK
    Dev Med Child Neurol 44:485-9. 2002
  9. ncbi Neuronal surface glycolytic enzymes are autoantigen targets in post-streptococcal autoimmune CNS disease
    Russell C Dale
    Department of Neuroinflammmation, Institute of Neurology, University College London, and Neurosciences Unit, Great Ormond Street Hospital and Institute of Child Health, London WC1N 3JJ, UK
    J Neuroimmunol 172:187-97. 2006
  10. ncbi Incidence of anti-brain antibodies in children with obsessive-compulsive disorder
    Russell C Dale
    Department of Child and Adolescent Psychiatry, PO Box 085, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 187:314-9. 2005

Collaborators

Detail Information

Publications26

  1. ncbi Post-streptococcal autoimmune disorders of the central nervous system
    Russell C Dale
    Neurosciences Unit, Great Ormond Street Hospital NHS Trust, London, UK
    Dev Med Child Neurol 47:785-91. 2005
    ..However, post-streptococcal disorders of the CNS remain a useful model of neuropsychiatric disease, which may improve our understanding of abnormal movements and behaviours in children...
  2. ncbi Encephalitis lethargica syndrome: 20 new cases and evidence of basal ganglia autoimmunity
    Russell C Dale
    Neurosciences Unit, Great Ormond Street Hospital and Institute of Child Health, and Department of Neuroinflammation, Institute of Neurology, University College London, UK
    Brain 127:21-33. 2004
    ..We believe an EL-like syndrome is still prevalent, and propose that this syndrome may be secondary to autoimmunity against deep grey matter neurons...
  3. ncbi Acute disseminated encephalomyelitis
    Russell C Dale
    Neurosciences Unit, Institute of Child Health and Great Ormond Street Hospital NHS Trust, and the Department of Neuroinflammation, Institute of Neurology, London, United Kingdom
    Semin Pediatr Infect Dis 14:90-5. 2003
    ..In view of the treatment differences between ADEM and viral encephalitis, being familiar with ADEM is essential for pediatricians managing acute neurological disorders...
  4. ncbi CSF and serum immune parameters in Sydenham's chorea: evidence of an autoimmune syndrome?
    Andrew J Church
    Neuroimmunology Unit, Neuroinflammation Department, Institute of Neurology, Room 917, Queen Square, London WC1N 3BG, UK
    J Neuroimmunol 136:149-53. 2003
    ..OCB were found in 46% of acute SC, ABGA were in 93% of acute SC and 50% of persistent SC was of IgG(1) and IgG(3) subclass. These findings support an autoantibody pathogenesis...
  5. ncbi Striatal encephalitis after varicella zoster infection complicated by Tourettism
    Russell C Dale
    Neurosciences Unit, Institute of Child Health and Great Ormond Street Hospital NHS Trust, London, United Kingdom
    Mov Disord 18:1554-6. 2003
    ..The patient subsequently developed a chronic tic disorder with attention deficit disorder. This case furthers the proposed association between Tourettism and the basal ganglia...
  6. ncbi Quantitative demonstration of intrathecal synthesis of high affinity immunoglobulin G in herpes simplex encephalitis using affinity-mediated immunoblotting
    Miles D Chapman
    Department of Neuroimmunology, Institute of Neurology, Queen Square, London, WC1N 3BG, UK
    J Neuroimmunol 185:130-5. 2007
    ..Digitisation of the blots enabled further analysis. We showed that the clones of antigen-specific IgG, which were produced intrathecally, were of higher relative affinity than polyclonal antigen-specific IgG...
  7. ncbi Childhood opsoclonus myoclonus
    Russell C Dale
    Neurosciences Unit, Institute of Child Health, University College, London, UK
    Lancet Neurol 2:270. 2003
  8. ncbi Post-streptococcal autoimmune dystonia with isolated bilateral striatal necrosis
    Russell C Dale
    Neurosciences Unit, Institute of Child Health, London, UK
    Dev Med Child Neurol 44:485-9. 2002
    ..Acute IBSN is part of the poststreptococcal autoimmune neuropsychiatric spectrum. An autoimmune aetiology should be considered in this phenotype, as immunomodulatory therapies may reduce morbidity and mortality...
  9. ncbi Neuronal surface glycolytic enzymes are autoantigen targets in post-streptococcal autoimmune CNS disease
    Russell C Dale
    Department of Neuroinflammmation, Institute of Neurology, University College London, and Neurosciences Unit, Great Ormond Street Hospital and Institute of Child Health, London WC1N 3JJ, UK
    J Neuroimmunol 172:187-97. 2006
    ..GAS also expresses glycolytic enzymes on cell surfaces that have 0-49% identity with human NGE, suggesting molecular mimicry and autoimmune cross-reactivity may be the pathogenic mechanism in post-streptococcal CNS disease...
  10. ncbi Incidence of anti-brain antibodies in children with obsessive-compulsive disorder
    Russell C Dale
    Department of Child and Adolescent Psychiatry, PO Box 085, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 187:314-9. 2005
    ..The proposed mediators are anti-basal ganglia antibodies (ABGA)...
  11. ncbi Adult-onset tic disorder, motor stereotypies, and behavioural disturbance associated with antibasal ganglia antibodies
    Mark J Edwards
    Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London, United Kingdom
    Mov Disord 19:1190-6. 2004
    ..We suggest that there might be a causal relationship between ABGA and the clinical syndrome in these cases and that ABGA should be considered as a possible etiology for adult-onset tics...
  12. ncbi Antibasal ganglia antibodies and PANDAS
    Davide Martino
    Mov Disord 20:116-7. 2005
  13. ncbi Antistreptolysin-O titers: implications for adult PANDAS. Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections
    Andrew J Church
    Am J Psychiatry 159:320. 2002
  14. ncbi Dementia-like presentation of striatal hypermetabolic state with antistriatal antibodies responsive to steroids
    Gabriel C Léger
    Neurology Service, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    Arch Neurol 61:754-7. 2004
    ..Hypermetabolic lesions of the striatum are rare. They usually involve autoimmunity and are associated with choreatic disorders such as Sydenham chorea, lupus, and the antiphospholipid antibody syndrome...
  15. ncbi Post-streptococcal autoimmune psychiatric and movement disorders in children
    Russell C Dale
    Br J Psychiatry 181:188-90. 2002
  16. ncbi Parkinsonian features after streptococcal pharyngitis
    Hilla Ben-Pazi
    Pediatric Department, Hadassah University Hospital, Ein Kerem, POB 12000, Jerusalem 91120, Israel
    J Pediatr 143:267-9. 2003
    ..We suggest that autoimmune antibodies may cause remitting parkinsonian signs subsequent to streptococcal tonsillitis as part of the spectrum of poststreptococcal CNS disease...
  17. ncbi Post-streptococcal autoimmune neuropsychiatric disease presenting as paroxysmal dystonic choreoathetosis
    Russell C Dale
    Department of Neurology, Great Ormond Street Hospital NHS Trust and Institute of Child Health, London, United Kingdom
    Mov Disord 17:817-20. 2002
    ..We propose that autoantibodies produced in post-streptococcal neuropsychiatric disease cause alteration in neurotransmission, possibly secondary to ion channel binding...
  18. ncbi New autoantibody mediated disorders of the central nervous system
    Bethan Lang
    Neurosciences Group, Department of Clinical Neurology, Weatherall Institute of Molecular Medicine, University of Oxford, UK
    Curr Opin Neurol 16:351-7. 2003
    ..This review summarizes the recent findings and assesses the evidence that these conditions are caused by the antibodies, using the criteria established for peripheral nervous system autoimmune diseases...
  19. ncbi Antineuronal antibody status and phenotype analysis in Tourette's syndrome
    Davide Martino
    Department of Neuroinflammation, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 22:1424-9. 2007
    ..14; P = 0.002; 95% confidence interval 0.04-0.49). ANeA status does not differentiate a specific phenotype of GTS...
  20. ncbi Early relapse risk after a first CNS inflammatory demyelination episode: examining international consensus definitions
    Russell C Dale
    Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, Australia
    Dev Med Child Neurol 49:887-93. 2007
    ..However, it is hoped that these new criteria may improve prognostic specificity and provide uniformity to future paediatric CNS demyelination research...
  21. ncbi Contemporary encephalitis lethargica presenting with agitated catatonia, stereotypy, and dystonia-parkinsonism
    Russell C Dale
    Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia
    Mov Disord 22:2281-4. 2007
    ..We believe these cases support the hypothesis that this syndrome is an inflammatory encephalitis that specifically effects dopamine neurotransmission...
  22. pmc Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein
    Kevin C O'Connor
    Center for Neurologic Diseases, Brigham and Women s Hospital, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA
    Nat Med 13:211-7. 2007
    ..MOG-specific autoantibodies were identified in a subset of ADEM but only rarely in adult-onset MS cases, indicating that MOG is a more prominent target antigen in ADEM than MS...
  23. ncbi Soluble adhesion molecules in acute disseminated encephalomyelitis
    Davide Martino
    Department of Neuroinflammation, Institute of Neurology, University College London, UK
    Pediatr Neurol 33:255-8. 2005
    ..Further larger studies are required including serial measurements and cerebrospinal fluid analysis...
  24. ncbi Three cases of central nervous system complications associated with Mycoplasma pneumoniae
    Paul M Candler
    Department of Neuroinflammation, Institute of Neurology, University College London, London, United Kingdom
    Pediatr Neurol 31:133-8. 2004
    ..Systematic investigation to discriminate between these two processes will be essential to select appropriate antibiotic and immunomodulatory therapies...
  25. ncbi Normal MRI neuroimaging and acute dancing eyes syndrome
    Russell C Dale
    Dev Med Child Neurol 44:356. 2002
  26. ncbi Acute disseminated encephalomyelitis: where does it start and where does it stop?
    Russell C Dale
    Discipline of Paediatrics and Child Health Faculty of Medicine, University of Sydney, Australia
    Dev Med Child Neurol 50:326-7. 2008