Research Topics
| Brian H CuthbertsonSummaryAffiliation: University of Aberdeen Country: UK Publications
| Collaborators
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Detail Information
Publications
Glycaemic control and prediction of ICU stayDavid Fallaha
Resuscitation 75:389-90. 2007
A pragmatic randomised, controlled trial of intensive care follow up programmes in improving longer-term outcomes from critical illness. The PRACTICAL studyBrian H Cuthbertson
Health Service Research Unit, Health Sciences Building, University of Aberdeen, Foresterhill, Aberdeen, UK
BMC Health Serv Res 7:116. 2007....
The impact of critical care outreach: is there one?Brian H Cuthbertson
Clinical Senior Lecturer in Critical Care and Consultant in Intensive Care Medicine, Health Services Research Unit, Health Sciences Building, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK
Crit Care 11:179. 2007..It is now time to ask some difficult questions about the future of outreach, including whether the lack of evidence should lead to disinvestment in such services...- Intracranial pressure measurement, induced hypothermia and barbiturate coma in meningitis associated with intractable raised intracranial pressureB H Cuthbertson
Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, Scotland AB25 2ZD, UK
Anaesthesia 59:908-11. 2004..We report the use of intracranial pressure monitoring, mild hypothermia and barbiturate coma in a patient with meningococcal meningitis complicated by raised intracranial pressure... - Utility of B-type natriuretic peptide in predicting perioperative cardiac events in patients undergoing major non-cardiac surgeryB H Cuthbertson
Health Services Research Unit, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, UK
Br J Anaesth 99:170-6. 2007..We hypothesized that they would identify individuals at increased risk of early cardiac complications after major non-cardiac surgery. The current study tests this hypothesis... 
The effects of etomidate on adrenal responsiveness and mortality in patients with septic shockBrian H Cuthbertson
Health Services Research Unit, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK
Intensive Care Med 35:1868-76. 2009....- N-terminal pro-B-type natriuretic peptide levels and early outcome after cardiac surgery: a prospective cohort studyB H Cuthbertson
Health Services Research Unit, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen AB25 2ZD, UK
Br J Anaesth 103:647-53. 2009..There are, however, limited data regarding the utility of NT-proBNP or BNP levels in patients undergoing cardiac surgery. The current study assesses the ability of NT-proBNP to predict early outcome in this setting... - Quality of life before and after intensive careB H Cuthbertson
Health Services Research Unit, Institute of Applied Health Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK
Anaesthesia 60:332-9. 2005..ICU patients experience a considerable longer-term burden of ill health... - Utility of B-type natriuretic peptide in predicting medium-term mortality in patients undergoing major non-cardiac surgeryBrian H Cuthbertson
Health Services Research Unit, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
Am J Cardiol 100:1310-3. 2007.... - B-type natriuretic peptide and the prediction of outcome in patients admitted to intensive careB H Cuthbertson
Medical School, University of Aberdeen, Foresterhill, Scotland
Anaesthesia 60:16-21. 2005..04) and in patients with raised creatinine > or = 110 micromol.l(-1) (p = 0.02). We concluded that B-type natriuretic peptide, measured soon after admission to intensive care, does not usefully predict outcome after intensive care... - Antibiotic-treated infections in intensive care patients in the UKB H Cuthbertson
Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, Scotland, UK
Anaesthesia 59:885-90. 2004..We conclude that the mean duration of treatment contrasts with existing published guidelines, highlighting the need for further studies on duration and efficacy of treatment in intensive care... - Post-traumatic stress disorder after critical illness requiring general intensive careBrian H Cuthbertson
Anaesthesia and Intensive Care, Medicine and Therapeutics, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, Scotland, UK
Intensive Care Med 30:450-5. 2004..To determine the incidence and severity of symptoms related to the diagnosis of post-traumatic stress disorder (PTSD) in a cohort of general ICU patients... - UK guidelines for the use of inhaled nitric oxide therapy in adult ICUs. American-European Consensus Conference on ALI/ARDSB H Cuthbertson
Anaesthesia and Intensive Care, Institute of Medical Sciences, Medical School, University of Aberdeen, Scotland
Intensive Care Med 23:1212-8. 1997..Our aim was to produce guidelines for the clinical application of inhaled NO in adult intensive care practice, based upon the current level of published information... - The utility of B-type natriuretic peptide in predicting postoperative cardiac events and mortality in patients undergoing major emergency non-cardiac surgeryB H Cuthbertson
Health Services Research Unit, University of Aberdeen, Aberdeen, Scotland AB25 2ZD, UK
Anaesthesia 62:875-81. 2007..In this small study, pre-operative BNP levels identify patients undergoing major emergency non-cardiac surgery who are at increased risk of early postoperative cardiac events. Larger studies are required to confirm these data... - Use of preoperative natriuretic peptides and echocardiographic parameters in predicting new-onset atrial fibrillation after coronary artery bypass grafting: a prospective comparative studyPatrick H Gibson
Department of Cardiology, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
Am Heart J 158:244-51. 2009..We prospectively compared the ability of echocardiographic parameters and the cardiac neurohormones, brain natriuretic peptide (BNP), and N-terminal pro-brain natriuretic peptide (NT-proBNP) to predict AF in this setting... - Usefulness of neutrophil/lymphocyte ratio as predictor of new-onset atrial fibrillation after coronary artery bypass graftingPatrick H Gibson
Department of Cardiology, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
Am J Cardiol 105:186-91. 2010..In conclusion, these results support an inflammatory etiology in postoperative AF but suggest that other factors are also important... - Relationship between postoperative cardiac troponin I levels and outcome of cardiac surgeryBernard L Croal
Department of Clinical Biochemistry, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom, AB25 2ZD
Circulation 114:1468-75. 2006..Interpretation of troponin levels in this setting may therefore be complex. This study assessed the prognostic significance of such measurements, taking into account potential confounding variables... - Uric acid levels and outcome from coronary artery bypass graftingGraham S Hillis
Department of Cardiology, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
J Thorac Cardiovasc Surg 138:200-5. 2009..Their utility in patients undergoing surgical revascularization has not, however, been assessed. We hypothesized that serum uric acid levels would predict the outcome of patients undergoing coronary artery bypass grafting... - Developing a team performance framework for the intensive care unitTom W Reader
School of Psychology, University of Aberdeen, Kings College, Aberdeen, Scotland, UK
Crit Care Med 37:1787-93. 2009..The purpose of this review is to consolidate the most robust findings from this research into an intensive care unit (ICU) team performance framework... - The relationship between renal function and outcome from heart valve surgeryPatrick H Gibson
Department of Cardiology, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, UK
Am Heart J 156:893-9. 2008..The prognostic importance of renal function in patients undergoing surgery for valvular heart disease is poorly defined. The current study addresses this issue... - N-terminal pro B-type natriuretic peptide is an independent predictor of postoperative myocardial injury in patients undergoing major vascular surgerySriram Rajagopalan
Department of Vascular Surgery, University of Aberdeen and Aberdeen Royal Infirmary, NHS Grampian, Aberdeen, United Kingdom
J Vasc Surg 48:912-7; discussion 917. 2008..We aimed to determine if N-terminal pro B-type natriuretic peptide (NT-pro-BNP), with its longer half-life and greater plasma stability, can predict postoperative myocardial injury in vascular patients... - Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass graftingPatrick H Gibson
Department of Cardiology, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
Am Heart J 154:995-1002. 2007..We hypothesized that the N/L ratio would predict the outcome of patients undergoing surgical revascularization... - Relation of left atrial volume to B-type natriuretic peptide levels in patients with stable chronic heart failureJustin L Barclay
Department of Cardiology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom
Am J Cardiol 98:98-101. 2006..This may help explain the relatively modest correlation between BNP and acute measures of LV filling and the heterogeneity in BNP levels in patients with stable heart failure... - Utility of B-type natriuretic peptide in predicting the level of peri- and postoperative cardiovascular support required after coronary artery bypass graftingBrian H Cuthbertson
Anaesthesia and Intensive Care, Medicine and Therapeutics, Medical School, University of Aberdeen, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, Scotland, UK
Crit Care Med 33:437-42. 2005.... - Use of inhaled nitric oxide in British intensive therapy unitsB H Cuthbertson
Institute of Medical Sciences, Medical School, University of Aberdeen, Foresterhill
Br J Anaesth 78:696-700. 1997..4%) satisfactory replies were received. We present the survey results and put forward recommendations based on current literature and our own clinical experience for the safe use of inhaled nitric oxide... - Can physiological variables and early warning scoring systems allow early recognition of the deteriorating surgical patient?Brian H Cuthbertson
Health Services Research Unit and Department of Public Health, University of Aberdeen, Foresterhill, Aberdeen, Aberdeen, Scotland, UK
Crit Care Med 35:402-9. 2007..We aimed to test the ability of physiologic variables, either alone or in existing early scoring systems, to predict major deterioration in a patient's condition and attempt to derive functions with superior accuracy... - Activated protein C inhibits chemotaxis and interleukin-6 release by human neutrophils without affecting other neutrophil functionsH F Galley
Academic Unit of Anaesthesia and Intensive Care, School of Medicine, University of Aberdeen, Aberdeen, UK
Br J Anaesth 100:815-9. 2008..The effects of APC on inflammatory responses have also been reported. Neutrophils are key cells involved in early host defence mechanisms in sepsis. We hypothesized that APC may have effects on neutrophil function... - Interdisciplinary communication in the intensive care unitT W Reader
School of Psychology, University of Aberdeen, Kings College, Aberdeen, Scotland, UK
Br J Anaesth 98:347-52. 2007..This study examines whether ICU doctors and nurses have a shared perception of interdisciplinary communication in the UK ICU... - Non-technical skills in the intensive care unitT Reader
Industrial Psychology Research Centre, King s College Old Aberdeen, Scotland, UK
Br J Anaesth 96:551-9. 2006..Examples of such research highlight the utility of these techniques... - Developing a placebo-controlled trial in surgery: issues of design, acceptability and feasibilityM K Campbell
Health Services Research Unit, University of Aberdeen, Aberdeen, UK
Trials 12:50. 2011.... - Communication skills and error in the intensive care unitTom W Reader
School of Psychology, University of Aberdeen, Kings College, Aberdeen, Scotland, UK
Curr Opin Crit Care 13:732-6. 2007..This review considers communication research recently conducted in the intensive care unit and other acute domains... - Critical care outwith the intensive care unitHolder Paul
Department of Anaesthesia and Intensive Care, Aberdeen Royal Infirmary, Aberdeen, Scotland
Clin Med 5:449-51. 2005 - Renal function and outcome from coronary artery bypass grafting: impact on mortality after a 2.3-year follow-upGraham S Hillis
Department of Cardiology, University of Aberdeen, Aberdeen Royal Infirmary, UK
Circulation 113:1056-62. 2006..Recent studies have suggested that estimated glomerular filtration rate (eGFR) is a more discriminatory measure. However, data on the utility of eGFR in predicting outcome from CABG are limited... - Exhaled nitric oxide as a marker of lung injury in coronary artery bypass surgeryB H Cuthbertson
Anaesthesia and Intensive Care, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK
Br J Anaesth 89:247-50. 2002..1. P = 0.67) and expired NO levels. CONCLUSIONS: Further work is required to test whether exhaled NO concentration may be useful in diagnosing the onset of acute lung injury in patients undergoing coronary artery bypass grafting... - Patient safety: helping medical students understand error in healthcareRona Patey
Department of Anaesthesia, Aberdeen Royal Infirmary, Aberdeen, UK
Qual Saf Health Care 16:256-9. 2007..A literature review did not reveal any patient safety courses in the core undergraduate medical curriculum. Therefore a new module was designed and piloted... - Evidence-based selection of theories for designing behaviour change interventions: using methods based on theoretical construct domains to understand clinicians' blood transfusion behaviourJill J Francis
Health Services Research Unit, University of Aberdeen, Aberdeen, UK
Br J Health Psychol 14:625-46. 2009..It was used here to investigate clinicians' transfusion behaviour in intensive care units (ICU). Evidence suggests that red blood cells transfusion could be reduced for some patients without reducing quality of care... - Activated protein C for the treatment of severe sepsisG Houston
Intensive Care Unit, Aberdeen Royal Infirmary, Aberdeen, UK
Clin Microbiol Infect 15:319-24. 2009..Significant doubt remains as to the role of recombinant human activated protein C in the management of severe sepsis, and this review aims to summarize the evidence both for and against its use... - Effectiveness and cost-effectiveness of arthroscopic lavage in the treatment of osteoarthritis of the knee: a mixed methods study of the feasibility of conducting a surgical placebo-controlled trial (the KORAL study)M K Campbell
Health Services Research Unit, University of Aberdeen, Aberdeen, UK
Health Technol Assess 14:1-180. 2010.... - Socio-economic status and early outcome from coronary artery bypass graftingP H Gibson
Department of Cardiology, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, UK
Heart 95:793-8. 2009..To determine the effects of socio-economic status (SES) on the outcome of coronary artery bypass grafting (CABG)... - Renal function, revascularization and riskGraham S Hillis
Eur Heart J 28:782-4. 2007 - Life after intensive care--it's life... but not as we know it!Brian H Cuthbertson
Crit Care Med 36:1668-9. 2008 - Psychological consequences of critical illness: aftercare or an afterthought?Alastair M Hull
Multidisciplinary Adult Psychotherapy Service, NHS Tayside, Murray Royal Hospital, Perth PH2 7BH
Br J Hosp Med (Lond) 68:474-6. 2007..As the physical care of individuals with critical illness has improved greater numbers have survived. However, until recently the psychological response to such critical illness has received comparatively little attention... - Evaluation of the cost-effectiveness of drotrecogin alfa (activated) for the treatment of severe sepsis in the United KingdomColin Green
Southampton Health Technology Assessment Centre, University of Southampton, UK
Int J Technol Assess Health Care 22:90-100. 2006..The aim of this study was to assess the cost-effectiveness of drotrecogin alfa (activated) compared with best supportive care in a UK cohort of adult intensive-care patients with severe sepsis... - Burnout in the ICU: potential consequences for staff and patient well-beingThomas W Reader
Intensive Care Med 34:4-6. 2008 - Optimising early warning scoring systemsBrian H Cuthbertson
Resuscitation 77:153-4. 2008 - The findings of the International Conference on Medical Emergency Teams are biased and misleadingRichard J Price
Crit Care Med 35:992-3. 2007