Alfred Cuschieri

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. pmc Different cellular response mechanisms contribute to the length-dependent cytotoxicity of multi-walled carbon nanotubes
    Dun Liu
    Institute for Medical Science and Technology IMSaT, University of Dundee, Wilson House, 1 Wurzburg Loan, Dundee Medipark, Dundee, DD2 1FD, UK
    Nanoscale Res Lett 7:361. 2012
  2. ncbi request reprint Initial experience with laparoscopic ultrasound-guided radiofrequency thermal ablation of hepatic tumours
    A Cuschieri
    Dept of Surgery, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Endoscopy 31:318-21. 1999
  3. ncbi request reprint Image display technology and image processing
    G Hanna
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Scotland
    World J Surg 25:1419-27. 2001
  4. pmc Influence of pathological tumour variables on long-term survival in resectable gastric cancer
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK
    Br J Cancer 86:674-9. 2002
  5. ncbi request reprint Tissue adhesives in endosurgery
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland
    Semin Laparosc Surg 8:63-8. 2001
  6. ncbi request reprint Human reliability analysis (HRA) techniques and observational clinical HRA
    Alfred Cuschieri
    Institute for Medical Science and Technology, University of Dundee and Scuola Superiore Sant Anna di Studi Universitari Pisa, Pisa, Italy
    Minim Invasive Ther Allied Technol 19:12-7. 2010
  7. ncbi request reprint [New technologies in laparoscopic surgery]
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Chirurg 72:252-60. 2001
  8. ncbi request reprint Laparoscopic gastric resection
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Surg Clin North Am 80:1269-84, viii. 2000
  9. ncbi request reprint Minimally invasive surgery: hepatobiliary-pancreatic and foregut
    A Cuschieri
    Dept of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Scotland, United Kingdom
    Endoscopy 32:331-44. 2000
  10. ncbi request reprint A new multitool for hand-assisted advanced laparoscopic surgery (HALS)
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland, UK
    Surg Endosc 17:1368-71. 2003

Collaborators

Detail Information

Publications108 found, 100 shown here

  1. pmc Different cellular response mechanisms contribute to the length-dependent cytotoxicity of multi-walled carbon nanotubes
    Dun Liu
    Institute for Medical Science and Technology IMSaT, University of Dundee, Wilson House, 1 Wurzburg Loan, Dundee Medipark, Dundee, DD2 1FD, UK
    Nanoscale Res Lett 7:361. 2012
    ..Results from chromogenic-based assays should be confirmed by trypan blue exclusion...
  2. ncbi request reprint Initial experience with laparoscopic ultrasound-guided radiofrequency thermal ablation of hepatic tumours
    A Cuschieri
    Dept of Surgery, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Endoscopy 31:318-21. 1999
    ..e. reduced heat sink effect, greater precision and improved assessment of the thermal ablative zone...
  3. ncbi request reprint Image display technology and image processing
    G Hanna
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Scotland
    World J Surg 25:1419-27. 2001
    ..In the diagnostic field, virtual reality surface anatomical and internal luminal rendering has opened a new chapter in diagnosis, screening, and treatment planning, the potential of which is only just being realized...
  4. pmc Influence of pathological tumour variables on long-term survival in resectable gastric cancer
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK
    Br J Cancer 86:674-9. 2002
    ..5, 95% CI 2.5-4.8). Patients with numerous eosinophils had a lower risk of death than those with none (Hazard Ratio=0.5, 95% CI 0.3-0.8). This association between survival and eosinophilic infiltration merits further study...
  5. ncbi request reprint Tissue adhesives in endosurgery
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland
    Semin Laparosc Surg 8:63-8. 2001
    ..In time, tissue glues and soldering will likely replace, in whole or in part, the use of sutures and staples for a variety of tissue approximation surgical procedures...
  6. ncbi request reprint Human reliability analysis (HRA) techniques and observational clinical HRA
    Alfred Cuschieri
    Institute for Medical Science and Technology, University of Dundee and Scuola Superiore Sant Anna di Studi Universitari Pisa, Pisa, Italy
    Minim Invasive Ther Allied Technol 19:12-7. 2010
    ....
  7. ncbi request reprint [New technologies in laparoscopic surgery]
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Chirurg 72:252-60. 2001
    ..Randomised controlled clinical trials are unsuited for the initial HTA of technology-dependent interventions, and for this reason, an alternative system, controlled stepwise evaluation (CSE) is proposed...
  8. ncbi request reprint Laparoscopic gastric resection
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Surg Clin North Am 80:1269-84, viii. 2000
    ..Evidence-based information on surgical management of gastric cancer and stromal stomach tumors is presented, and the laparoscopic procedures that can be undertaken without compromising the clinical outcome are surveyed...
  9. ncbi request reprint Minimally invasive surgery: hepatobiliary-pancreatic and foregut
    A Cuschieri
    Dept of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Scotland, United Kingdom
    Endoscopy 32:331-44. 2000
    ..The early reported outcome for internal drainage of pancreatic pseudocysts, enucleation of benign insulinomas, and distal pancreatic resections has been good, but the experience is limited...
  10. ncbi request reprint A new multitool for hand-assisted advanced laparoscopic surgery (HALS)
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland, UK
    Surg Endosc 17:1368-71. 2003
    ..Here we report on the development, testing, and evaluation of a small reusable multitool that hangs from the little finger of the internal assisting hand of the surgeon when not in use...
  11. ncbi request reprint Lest we forget the surgeon
    - Sir Alfred Cuschieri
    Surgical Skills Unit, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Semin Laparosc Surg 10:141-8. 2003
    ..Error-tolerant operating medical systems should enable detection, reporting, and targeted reduction of errors...
  12. ncbi request reprint Multimedia article. Laparoscopic transection choledochoduodenostomy
    A Cuschieri
    Scuola Superiore Sant Anna di Studi Universitari e di Perfezionamento, Pisa, Italy
    Surg Endosc 19:728. 2005
    ..0 and 2.5 h. The results have been excellent, with no deaths and a low postoperative morbidity (chest infection in one patient) and median postoperative hospital stay of 5 days...
  13. ncbi request reprint What do master surgeons think of surgical competence and revalidation?
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, DD1 9SY, Dundee, Scotland, UK
    Am J Surg 182:110-6. 2001
    ..There has been on-going debate and public interest in surgical competence in recent years...
  14. pmc Poly-l-lysine-coated magnetic nanoparticles as intracellular actuators for neural guidance
    Cristina Riggio
    Institute of Life Science, Scuola Superiore Sant Anna, Piazza Martiri della Libertà, Pisa, Italy
    Int J Nanomedicine 7:3155-66. 2012
    ..Unfortunately, the materials currently available on the market do not satisfy these criteria; therefore, this work attempts to overcome these deficiencies...
  15. pmc Zinc oxide nanoparticles as selective killers of proliferating cells
    Liuba Taccola
    Department of Oncology, Transplantation and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy
    Int J Nanomedicine 6:1129-40. 2011
    ....
  16. pmc Magnetic retraction of bowel by intraluminal injectable cyanoacrylate-based magnetic glue
    Zhigang Wang
    Institute for Medical Science and Technology IMSaT, Wilson House, University of Dundee, Dundee DD2 1FD, UK
    Biomed Res Int 2013:526512. 2013
    ..11 ± 0.34 N (n = 20), with use of 5 and 10 mm probes, respectively. The results indicate that the formation of an intraluminal coagulum based on SS410- μPs and Loctite 4014 produces sufficient magnetic retraction for bowel retraction...
  17. ncbi request reprint Mucoadhesive polymer films for tissue retraction in laparoscopic surgery: Ex-vivo study on their mechanical properties
    Zhigang Wang
    Institute of Medical Science and Technology IMSaT, University of Dundee, Wilson House, Medipark, Dundee DD2 1FD, UK
    Biomed Mater Eng 24:445-51. 2014
    ....
  18. ncbi request reprint Retraction by surface ferromagnetisation of target tissues: preliminary studies on feasibility of magnetic retraction for endoscopic surgery
    Zhigang Wang
    Institute for Medical Science and Technology, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, UK
    Surg Endosc 22:1838-44. 2008
    ..This paper describes a pilot study of surface magnetic retraction of the gastric mucosa to facilitate resection...
  19. ncbi request reprint Optimum shadow-casting illumination for endoscopic task performance
    Rajineesh K Mishra
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, Dundee, Scotland
    Arch Surg 139:889-92. 2004
    ..Task performance improves with the use of a balanced degree of shadow and illumination compared with no or maximum shadow contrast; and overhead shadow-casting illumination is better than side illumination...
  20. pmc Hybrid gold-iron oxide nanoparticles as a multifunctional platform for biomedical application
    Clare Hoskins
    Institute for Medical Science and Technology, University of Dundee, UK
    J Nanobiotechnology 10:27. 2012
    ..The unique properties of both the iron oxide (magnetic) and gold (surface plasmon resonance) result in a multimodal platform for use as MRI contrast agents and as a nano-heater...
  21. doi request reprint Image-based 3D modeling and validation of radiofrequency interstitial tumor ablation using a tissue-mimicking breast phantom
    Zhigang Wang
    Institute for Medical Science and Technology, University of Dundee, Wilson House, 1 Wurzburg Loan, Dundee, DD2 1FD, UK
    Int J Comput Assist Radiol Surg 7:941-8. 2012
    ..Patient-specific image-based 3D modeling for thermal ablation simulation was developed to optimize treatment protocols that improve treatment efficacy...
  22. doi request reprint Carbon nanotube-mediated wireless cell permeabilization: drug and gene uptake
    Vittoria Raffa
    Medical Science Lab, Scuola Superiore Sant Anna, Pisa, 56127, Italy
    Nanomedicine (Lond) 6:1709-18. 2011
    ..They can be used to induce cell permeabilization in order to transfer drugs (normally impermeable to cell membranes) both in in vitro and in vivo models...
  23. doi request reprint In vitro and in vivo biocompatibility testing of functionalized carbon nanotubes
    Gianni Ciofani
    Scuola Superiore Sant Anna, Pisa, Italy
    Methods Mol Biol 625:67-83. 2010
    ..Moreover, in vivo neurocompatibility tests were carried out through injections in mouse brains...
  24. doi request reprint Ferromagnetization of target tissues by interstitial injection of ferrofluid: formulation and evidence of efficacy for magnetic retraction
    Zhigang Wang
    Institute for Medical Science and Technology, School of Engineering, Physics and Mathematics, University of Dundee, Dundee DD2 1FD, UK
    IEEE Trans Biomed Eng 56:2244-52. 2009
    ..The results of this study indicate that ferromagnetization of tissue can be used to facilitate localized tissue retraction and resection...
  25. doi request reprint Proficiency assessment of gesture analysis in laparoscopy by means of the surgeon's musculo-skeleton model
    Filippo Cavallo
    The BioRobotics Institute, Scuola Superiore Sant Anna, Pisa, Italy
    Ann Surg 255:394-8. 2012
    ....
  26. ncbi request reprint Elasticity of the living abdominal wall in laparoscopic surgery
    Chengli Song
    Department of Surgery and Molecular Oncology, University of Dundee, Dundee DD1 9SY, UK
    J Biomech 39:587-91. 2006
    ..Based on this study, a mechanical abdominal wall lift and a surgical simulator for safe/ergonomic port placements are under development...
  27. ncbi request reprint Optimal angle between instrument shaft and handle for laparoscopic bowel suturing
    Shabeer Ahmed
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland
    Arch Surg 139:89-92. 2004
    ..To determine the optimal angle between the handle and instrument shaft for endoscopic suturing...
  28. ncbi request reprint Influence of handle design on the surgeon's upper limb movements, muscle recruitment, and fatigue during endoscopic suturing
    T A Emam
    Department of Surgery and Molecular Oncology and Surgical Skills Unit, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland
    Surg Endosc 15:667-72. 2001
    ..These differences translate to better and more efficient task performance with enhanced comfort...
  29. ncbi request reprint Optimum view distance for laparoscopic surgery
    G El Shallaly
    Monklands Hospital, Airdrie, Scotland, UK
    Surg Endosc 20:1879-82. 2006
    ..One of the important factors influencing visualization is the viewing distance between the surgeon and the monitor. This was the subject of the current investigation...
  30. doi request reprint Magnetoporation and magnetolysis of cancer cells via carbon nanotubes induced by rotating magnetic fields
    Dun Liu
    Institute for Medical Science and Technology, University of Dundee, Dundee Medipark, Dundee, United Kingdom
    Nano Lett 12:5117-21. 2012
    ..Findings of this study have potential clinical applications including enhanced tumor cell poration for targeted cancer chemotherapy and mechanical ablation of tumors...
  31. pmc The cytotoxicity of polycationic iron oxide nanoparticles: common endpoint assays and alternative approaches for improved understanding of cellular response mechanism
    Clare Hoskins
    Institute for Medical Science and Technology, University of Dundee, UK
    J Nanobiotechnology 10:15. 2012
    ..These results were compared with AFM topography imaging carried out on fixed cell lines...
  32. doi request reprint Rapid and efficient cell labeling with a MRI contrast agent by electroporation in the presence of protamine sulfate
    Lijun Wang
    Institute for Medical Science and Technology IMSaT, School of Engineering, Physics and Mathematics, University of Dundee, Dundee, UK
    Nanomedicine (Lond) 4:305-15. 2009
    ..To investigate various protocols for magnetic labeling of human cancer cells with ferumoxides with a view to developing an effective and fast technique for potential clinical use in MRI...
  33. doi request reprint Magnetic carbon nanotubes: a new tool for shepherding mesenchymal stem cells by magnetic fields
    Orazio Vittorio
    Medical Science Laboratory, Scuola Superiore Sant Anna, Pisa, Italy
    Nanomedicine (Lond) 6:43-54. 2011
    ..We investigated the interaction between magnetic carbon nanotubes (CNTs) and mesenchymal stem cells (MSCs), and their ability to guide these intravenously injected cells in living rats by using an external magnetic field...
  34. pmc Can armrests improve comfort and task performance in laparoscopic surgery?
    Raffaele Galleano
    University of Dundee, Dundee, UK
    Ann Surg 243:329-33. 2006
    ..The study sought to determine whether the support provided by armrests influenced task quality, task efficiency, and surgeon comfort during laparoscopic surgery...
  35. ncbi request reprint Carbon nanotube-enhanced cell electropermeabilisation
    Vittoria Raffa
    Medical Science Lab, Scuola Superiore Sant Anna, Piazza Martiri della Libertà 33, Pisa, Italy
    Bioelectrochemistry 79:136-41. 2010
    ....
  36. ncbi request reprint Influence of purity and surface oxidation on cytotoxicity of multiwalled carbon nanotubes with human neuroblastoma cells
    Orazio Vittorio
    Center for Research in Micro and Nano engineering CRIM Laboratory, Scuola Superiore Sant Anna, Pisa, Italy
    Nanomedicine 5:424-31. 2009
    ..Our results indicate that concentrations of 5-10 mug/mL MWCNTs seem ideal for studies on the design and development of artificial MWCNT nanovectors for gene and drug therapy against cancer...
  37. pmc Multiwall carbon nanotubes as MRI contrast agents for tracking stem cells
    Orazio Vittorio
    Medical Science Laboratory, Scuola Superiore Sant Anna, Pisa, Italy
    Nanotechnology 22:095706. 2011
    ..These results suggest that the MRI contrast agent properties of the MWCNTs could be used in vivo for stem cell tracking/imaging and during MWCNT-mediated targeted electro-chemotherapy of tumours...
  38. doi request reprint A micropower miniature piezoelectric actuator for implantable middle ear hearing device
    Zhigang Wang
    University of Dundee, Dundee, UK
    IEEE Trans Biomed Eng 58:452-8. 2011
    ..The actuator power consumption and its generated equivalent sound pressure level are also discussed. In conclusion, the actuator has advantages of small size, lightweight, and micropower consumption for potential use as IMHEDs...
  39. ncbi request reprint Management of patients with gallstones and ductal calculi
    Alfred Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK
    Lancet 360:739-40. 2002
  40. ncbi request reprint Effect of the angle between the optical axis of the endoscope and the instruments' plane on monitor image and surgical performance
    P V Patil
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland, UK
    Surg Endosc 18:111-4. 2004
    ....
  41. ncbi request reprint Measurements and modelling of the compliance of human and porcine organs
    F J Carter
    Department of Surgery and Molecular Oncology, Level 6, Ninewells Hospital and Medical School, DD1 9SY, Scotland, Dundee, UK
    Med Image Anal 5:231-6. 2001
    ..It was found that an exponential stress-strain law could accurately fit uniform stress test data and that subsequent finite element modelling for non-uniform stress around a small indentor matched measured force characteristics...
  42. ncbi request reprint Role of video-laparoscopy in the staging of intra-abdominal lymphomas and gastrointestinal cancer
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Semin Surg Oncol 20:167-72. 2001
    ..In some centres, laparoscopic staging is being conducted by gastroenterologists and hepatologists. This raises issues of safety and ability to undertake certain procedures that may be necessary during the laparoscopic staging...
  43. ncbi request reprint Ergonomics of hand-assisted laparoscopic surgery
    G B Hanna
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Semin Laparosc Surg 8:92-5. 2001
    ..Further progress and increased scope of HALS will only be achieved with designs based on ergonomic research...
  44. ncbi request reprint Laparoscopic hand-assisted hepatic surgery
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland
    Semin Laparosc Surg 8:104-13. 2001
    ..The device was effective in maintaining pneumoperitoneum in all cases. All operations were completed with the HALS approach...
  45. ncbi request reprint Impact of fenestrations and surface profiling on the holding of tissue by parallel occlusion laparoscopic graspers
    Andrew W Brown
    Surgical Technology and Robotics Group, Institute for Medical Science and Technology, University of Dundee, 1, Wurzburg Loan, Dundee, DD2 1FD, Scotland, UK
    Surg Endosc 28:1277-83. 2014
    ..g., fenestrations and surface profiling on grasping efficiency defined as resistance to slip without inflicting trauma, is limited...
  46. pmc Combination of polymer technology and carbon nanotube array for the development of an effective drug delivery system at cellular level
    Cristina Riggio
    Scuola Superiore Sant Anna, Piazza Martiri della Libertà, 33, 56127, Pisa, Italy
    Nanoscale Res Lett 4:668-73. 2009
    ..The implication of this study opens several perspectives in particular in the field of neurointerfaces, combining several functions into a single platform...
  47. ncbi request reprint Shape memory alloy clip for compression colonic anastomosis
    Chengli Song
    Department of Surgery and Molecular Oncology, University of Dundee, DD1 9SY United Kingdom
    J Biomech Eng 127:351-4. 2005
    ..The design of the anastomosis clip was optimized for safe, simple, and effective use in colon surgery...
  48. ncbi request reprint Clamping the small intestine during surgery: predicted and measured sealing forces
    T Frank
    Department of Surgery, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Proc Inst Mech Eng H 209:111-5. 1995
    ..Using these results and known intraluminal pressures in the human gastrointestinal tract, a bowel clamp must apply around 7 N to prevent seepage and the coefficient of friction between clamp and bowel should be between 0.6 and 0.9...
  49. ncbi request reprint Ergonomic principles of task alignment, visual display, and direction of execution of laparoscopic bowel suturing
    T A Emam
    Department of Surgery and Molecular Oncology and Surgical Skills Unit, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland
    Surg Endosc 16:267-71. 2002
    ..Our objective was to determine the optimum physical alignment, visual display, and direction of intracorporeal laparoscopic bowel suturing using infrared motion analysis and telemetric electromyography (EMG) systems...
  50. ncbi request reprint Characterizing the "gold standard" image for laparoscopic surgery
    S I Brown
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital and Medical School, DD1 9SY, Dundee, UK
    Surg Endosc 18:1192-5. 2004
    ..The term "gold standard" is often used to describe preferred display devices, frequently without substantiating evidence. A meaningful and objective measure of display quality for endoscopic surgery is required...
  51. ncbi request reprint Coaxial curved instrumentation for minimal access surgery
    A Cuschieri
    Department of Surgery, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Endosc Surg Allied Technol 1:303-5. 1993
    ..Coaxial instruments enhance the scope of minimal access surgery and have distinct advantages over the traditional straight instruments...
  52. ncbi request reprint Optimization of the projection screen in a display system for minimal access surgery
    S I Brown
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK
    Surg Endosc 17:1251-5. 2003
    ..It is ergonomically advantageous to locate the image adjacent to the surgeon's hands by projection onto a sterile screen, but there has been no research into the optimal screen material...
  53. ncbi request reprint Real-time thermography during energized vessel sealing and dissection
    P A Campbell
    Department of Surgery and Molecular Oncology, Ninewells Hospital, Dundee University, Dundee DD1 9SY, Scotland
    Surg Endosc 17:1640-5. 2003
    ..The thermal imaging measurements were then correlated with histopathologic studies. The overall value of in situ thermography as an adjunct to energized surgical dissection systems was also assessed...
  54. ncbi request reprint The importance of physics to progress in medical treatment
    Andreas Melzer
    Institute for Medical Science and Technology, University of Dundee, UK
    Lancet 379:1534-43. 2012
    ..We also discuss some of the fundamental physical principles involved in the application of each treatment to medical practice...
  55. doi request reprint Economic evaluation of da Vinci-assisted robotic surgery: a systematic review
    Giuseppe Turchetti
    Scuola Superiore Sant Anna, Pisa, Italy
    Surg Endosc 26:598-606. 2012
    ..5 million for each unit. This systematic review documents major variability in the reported cost evaluation studies of da Vinci robot-assisted operations compared with those performed by the direct manual laparoscopic approach...
  56. pmc How safe is high-power ultrasonic dissection?
    Tarek A Emam
    Department of Surgery and Molecular Oncology and Surgical Skills Unit, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland
    Ann Surg 237:186-91. 2003
    ..To evaluate the safety of ultrasonic dissection...
  57. ncbi request reprint Conversions during laparoscopic cholecystectomy: risk factors and effects on patient outcome
    Benjie Tang
    Cuschieri Skills Centre, University of Dundee, Scotland
    J Gastrointest Surg 10:1081-91. 2006
    ..There is consensus on certain individual risk factors and their additive effect on the likelihood of conversion. Predictive systems based on these factors appear to be useful in selection of cases for resident training...
  58. ncbi request reprint Thermographic assessment of tumor growth in mouse xenografts
    Chengli Song
    Department of Surgery and Molecular Oncology, University of Dundee, Scotland
    Int J Cancer 121:1055-8. 2007
    ..The findings of the study indicate that thermographic imaging might have considerable potential in monitoring human tumor xenografts and their response to anticancer drugs...
  59. ncbi request reprint Shadow depth cues and endoscopic task performance
    George B Hanna
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Arch Surg 137:1166-9. 2002
    ..A shadow-inducing laparoscopic system improves task performance...
  60. ncbi request reprint The performance of master surgeons on the Advanced Dundee Endoscopic Psychomotor Tester: contrast validity study
    Nader K Francis
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland, UK
    Arch Surg 137:841-4. 2002
    ..The contrast validity of the Advanced Dundee Endoscopic Psychomotor Tester (ADEPT) was determined by comparing the performance of "master surgeons" with that of surgical trainees (also called junior surgeons) on the system...
  61. pmc Abdominal wall lift versus positive-pressure capnoperitoneum for laparoscopic cholecystectomy: randomized controlled trial
    Afshin Alijani
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, Dundee, Scotland
    Ann Surg 239:388-94. 2004
    ..To compare intraoperative cardiac function, postoperative cognitive recovery, and surgical performance of laparoscopic cholecystectomy with abdominal wall lift (AWL) versus positive-pressure capnoperitoneum (PPCpn)...
  62. doi request reprint Thermal spread and heat absorbance differences between open and laparoscopic surgeries during energized dissections by electrosurgical instruments
    C Song
    Institute for Medical Science and Technology, University of Dundee, Wilson House, Dundee, DD2 1FD, Scotland, UK
    Surg Endosc 23:2480-7. 2009
    ....
  63. ncbi request reprint Extent of innate dexterity and ambidexterity across handedness and gender: Implications for training in laparoscopic surgery
    F H F Elneel
    Cuschieri Skills Centre, University of Dundee, Scotland, Italy
    Surg Endosc 22:31-7. 2008
    ..As innate dexterity is considered one of the important predictors of eventual operative competence, an experimental human factors study was conducted to determine innate dexterity and ambidexterity across handedness and gender...
  64. ncbi request reprint Perceptual aspects of two-dimensional and stereoscopic display techniques in endoscopic surgery: review and current problems
    J Hofmeister
    Department of Psychology, University of Dundee, Dundee, Scotland
    Semin Laparosc Surg 8:12-24. 2001
    ....
  65. ncbi request reprint Improving the retention of suturing needles in surgical graspers
    S I Brown
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK
    Surg Endosc 18:1605-7. 2004
    ..Needle swivel is particularly prevalent when needles are not held transversely in the jaws, but it is difficult to maintain a transverse grasp during surgery. An improved swivel-resistant grasper design is proposed...
  66. pmc The prognostic significance of the accumulation of p53 tumour-suppressor gene protein in gastric adenocarcinoma
    B V Joypaul
    Department of Surgery, University of Dundee, Ninewells Hospital and Medical School, UK
    Br J Cancer 69:943-6. 1994
    ..6 and 11.4 months respectively). These data suggest that overexpression of the p53 oncoprotein is an independent marker of shortened survival in gastric cancer patients...
  67. ncbi request reprint Effect of fixation of shoulder and elbow joint movement on the precision of laparoscopic instrument manipulations
    P V Patil
    Surgical Skills Unit and Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland, UK
    Surg Endosc 19:366-8. 2005
    ..The aim of this study was to investigate the effect of fixation of shoulder and elbow joint movement on the precision of laparoscopic instrument manipulations...
  68. ncbi request reprint Endoscopic subtotal oesophagectomy for cancer using the right thoracoscopic approach
    A Cuschieri
    Department of Surgery, Ninewells Hospital and Medical School, University of Dundee, UK
    Surg Oncol 2:3-11. 1993
    ....
  69. ncbi request reprint Comparison of orthodox versus off-optical axis endoscopic manipulations
    T A Emam
    Department of Surgery and Molecular Oncology and Surgical Skills Unit, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland
    Surg Endosc 16:401-5. 2002
    ..This experimental study was undertaken to compare this orthodox versus the off-optical axis endoscopic manipulations regarding the performance parameters and motion analysis and muscle work of the surgeon's dominant upper limb...
  70. ncbi request reprint Technological aspects of minimal access surgery
    T G Frank
    Department of Surgery, Ninewells Hospital and Medical School, University of Dundee
    Proc Inst Mech Eng H 211:129-44. 1997
    ..This paper describes the development, current status and future prospects of MAS from a technological perspective...
  71. ncbi request reprint Competence assessment of laparoscopic operative and cognitive skills: Objective Structured Clinical Examination (OSCE) or Observational Clinical Human Reliability Assessment (OCHRA)
    B Tang
    Cuschieri Skills Centre, Level 5, Ninewells Hospital, Dundee DD1 9SY, Scotland
    World J Surg 30:527-34. 2006
    ....
  72. ncbi request reprint Comparison of conventional and gaze-down imaging in laparoscopic task performance
    S I Brown
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, United Kingdom
    Surg Endosc 17:586-90. 2003
    ..Video projection systems project the image onto a screen placed close to the hands. This is said to be ergonomically superior. To evaluate this approach, a proprietary projection system (PS) was compared to a monitor display (MD)...
  73. ncbi request reprint Endoscopic oesophageal myotomy for specific motility disorders and non-cardiac chest pain
    A Cuschieri
    Dept of Surgery, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Endosc Surg Allied Technol 1:280-7. 1993
    ..Our experience indicates that long myotomy is successful but longer term follow-up is required to assess its therapeutic role...
  74. ncbi request reprint Analysis of errors enacted by surgical trainees during skills training courses
    B Tang
    Cuschieri Skills Centre, Ninewells Hospital, Dundee, UK
    Surgery 138:14-20. 2005
    ..This issue is particularly relevant to the training of surgeons and was addressed by our study...
  75. ncbi request reprint Non-mammalian vertebrate embryos as models in nanomedicine
    Martina Giannaccini
    Department of Biology, Cell and Developmental Biology Unit, Universita di Pisa, Pisa, Italy Institute of Life Science, Scuola Superiore Sant Anna, Pisa, Italy Electronic address
    Nanomedicine 10:703-19. 2014
    ..This review examines and discusses the biomedical applications and the interaction of nano-materials with embryonic systems, focusing on non-mammalian vertebrate models, such as chicken, zebrafish and Xenopus...
  76. ncbi request reprint Distribution of innate ability for surgery amongst medical students assessed by an advanced virtual reality surgical simulator
    Andrea Moglia
    EndoCAS, Center for Computer Assisted Surgery, University of Pisa, Edificio 102, Via Paradisa 2, 56124, Pisa, Italy
    Surg Endosc 28:1830-7. 2014
    ..Yet in most countries, the current selection process of surgical trainees does not include aptitude testing for the psychomotor and manipulative skills of candidates...
  77. pmc Tumour cell labelling by magnetic nanoparticles with determination of intracellular iron content and spatial distribution of the intracellular iron
    Zhigang Wang
    Institute for Medical Science and Technology, University of Dundee, Dundee DD2 1FD, UK
    Int J Mol Sci 14:9111-25. 2013
    ....
  78. pmc Dilemmas in the reliable estimation of the in-vitro cell viability in magnetic nanoparticle engineering: which tests and what protocols?
    Clare Hoskins
    Institute for Medical Science and Technology IMSaT, Wilson House, 1 Wurzburg Loan, University of Dundee, Dundee, DD2 1FD, UK
    Nanoscale Res Lett 7:77. 2012
    ..These findings highlight the importance of assay selection and of dissection of different cellular responses in in-vitro characterisation of nanostructures...
  79. ncbi request reprint [Laparoscopic surgery in Europe. Where are we going?]
    Alfred Cuschieri
    Scuola Superiore Sant Anna di Studi Universitari, Pisa, Italy
    Cir Esp 79:10-21. 2006
    ..Problems faced by laparoscopic surgery: quality guarantees in laparoscopic surgery, training the future laparoscopic generation, and allocation of sufficient material and human resources to laparoscopic surgery and its subspecialties...
  80. ncbi request reprint Pancreatic necrosis: pathogenesis and endoscopic management
    Alfred Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Semin Laparosc Surg 9:54-63. 2002
    ..The technique of laparoscopic infracolic pancreatic necrosectomy and irrigation of the lesser sac is described in detail...
  81. pmc Instrument for objective assessment of appropriateness of surgical bed occupancy: validation study
    Afshin Alijani
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, Dundee DD1 9SY
    BMJ 326:1243-4. 2003
  82. pmc Nature of human error: implications for surgical practice
    Alfred Cuschieri
    Department of Surgery, Division of Medical Sciences, Scuola Superiore S Anna di Studi Universitari, Pisa, Italy
    Ann Surg 244:642-8. 2006
    ....
  83. ncbi request reprint Detachable clamps for minimal access surgery
    T Frank
    Department of Surgery, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Proc Inst Mech Eng H 209:117-20. 1995
    ..The excellent holding and atraumatic characteristics of the detachable clamp have been confirmed by use in laparoscopic and thoracoscopic surgery on the gastrointestinal tract...
  84. pmc Parietal cell carcinoma of the stomach: association with long-term survival after curative resection
    D Byrne
    Department of Surgery, Ninewells Hospital and Medical School, Dundee, UK
    Br J Cancer 58:85-7. 1988
    ..This study suggests that gastric parietal cell carcinoma carries a good prognosis after curative resection despite the advanced stage at presentation...
  85. ncbi request reprint Endoscopic ultrasonic dissection for thoracoscopic and laparoscopic surgery
    A Cuschieri
    Department of Surgery, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Surg Endosc 7:197-9. 1993
    ....
  86. pmc Patient survival after D1 and D2 resections for gastric cancer: long-term results of the MRC randomized surgical trial. Surgical Co-operative Group
    A Cuschieri
    University Department of Surgery, Ninewells Hospital and Medical School, Dundee, UK
    Br J Cancer 79:1522-30. 1999
    ..However, the possibility that D2 resection without pancreatico-splenectomy may be better than standard D1 resection cannot be dismissed by the results of this trial...
  87. ncbi request reprint Thoracoscopic subtotal oesophagectomy
    A Cuschieri
    Dept of Surgery, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Endosc Surg Allied Technol 2:21-5. 1994
    ..The median postoperative stay was 12 days (range 9-30 days). It is suggested that the prone position has technical advantages and reduces the postoperative respiratory complications...
  88. ncbi request reprint Reliability of the Advanced Dundee Endoscopic Psychomotor Tester for bimanual tasks
    N K Francis
    Department of Surgery nad Surgical Skills Unit, Ninewells Hospital and Medical School, University of Dundee, Scotland
    Arch Surg 136:40-3. 2001
    ..A coefficient alpha of.98 was observed between the different tasks of ADEPT. CONCLUSION: These findings confirm that ADEPT is a reliable system for assessment of bimanual endoscopic task performance...
  89. ncbi request reprint Laparoscopic surgery: current status, issues and future developments
    A Cuschieri
    Scuola Superiore Sant Anna di Studi Universitari, Pisa, Italy
    Surgeon 3:125-30, 132-3, 135-8. 2005
    ..These concern mainly quality assurance, training, resource allocation, assessment of competence and tiers of laparoscopic surgical practice in line with the changing situation facing the next generation of surgeons...
  90. ncbi request reprint Epistemology of visual imaging in endoscopic surgery
    A Cuschieri
    Scuola Superiore S Anna di Studi Universitari, P zza dei Matiri della Libertà, Pisa, Italy
    Surg Endosc 20:S419-24. 2006
    ..Data from visual ergonomic experimental studies indicate that the best performance in endoscopic surgery is obtained by frontal gaze-down viewing because this restores the alignment of the visual with the motor axes of the operator...
  91. ncbi request reprint Reliability of the Dundee Endoscopic Psychomotor Tester (DEPT) for dominant hand performance
    N K Francis
    Department of Surgery and Molecular Oncology, Surgical Skills Unit, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland, UK
    Surg Endosc 15:673-6. 2001
    ..Coefficient a was > 0.7 for all parameters. CONCLUSION: DEPT provides a reliable method for the objective assessment of single-handed endoscopic performance in terms of aiming and force exerted on the target plate...
  92. ncbi request reprint In situ ablation of hepatic tumors
    A Cuschieri
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland
    Semin Laparosc Surg 8:25-41. 2001
    ....
  93. ncbi request reprint Multimedia article. Laparoscopic infracolic necrosectomy for infected pancreatic necrosis
    G D Adamson
    Surgical Skills Unit, Ninewells Hospital and Medical School, University of Dundee, Scotland, United Kingdom
    Surg Endosc 17:1675. 2003
    ..On completion of the necrosectomy, two large drains are inserted into the lesser sac for postoperative irrigation. The experience with this technique has been favorable with a patient survival of 85%...
  94. ncbi request reprint Abdominal wall lift systems in laparoscopic surgery: gasless and low-pressure systems
    A Alijani
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, Dundee, Scotland
    Semin Laparosc Surg 8:53-62. 2001
    ..This problem is overcome by combination of AWL with low-pressure (3 to 4 mm Hg) pneumoperitoneum. This combination provides good surgical exposure without adverse cardiovascular consequences...
  95. ncbi request reprint Mechanical properties of the human abdominal wall measured in vivo during insufflation for laparoscopic surgery
    C Song
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, Scotland
    Surg Endosc 20:987-90. 2006
    ..Carbon dioxide insufflation of the peritoneal cavity for laparoscopic surgery offers a unique opportunity to measure some mechanical properties of the human abdominal wall that hitherto have been difficult to obtain...
  96. ncbi request reprint Bilateral endoscopic splanchnicectomy through a posterior thoracoscopic approach
    A Cuschieri
    Department of Surgery, Ninewells Hospital and Medical School, University of Dundee, UK
    J R Coll Surg Edinb 39:44-7. 1994
    ..Bilateral thoracoscopic total splanchnicectomy merits further evaluation in patients with pancreatic pain. No complications including hypotension have been encountered...
  97. ncbi request reprint Long-term comparative outcome between laparoscopic total Nissen and Toupet fundoplication: Symptomatic relief, patient satisfaction and quality of life
    B Sgromo
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, DD1 9SY, UK
    Surg Endosc 22:1048-53. 2008
    ..This study compares the long-term outcome of total (Nissen) and partial (Toupet) fundoplication, performed in a single institution, by evaluating symptoms and quality of life...
  98. ncbi request reprint Analysis of technical surgical errors during initial experience of laparoscopic pyloromyotomy by a group of Dutch pediatric surgeons
    B Tang
    Surgical Skills Unit, Ninewells Hospital and Medical School, University of Dundee, DD1 9SY, Dundee, Scotland, United Kingdom
    Surg Endosc 18:1716-20. 2004
    ..The aim of the present study was to examine the performance of LPM by pediatric surgeons during the initial stages of their experience...
  99. ncbi request reprint Identification and categorization of technical errors by Observational Clinical Human Reliability Assessment (OCHRA) during laparoscopic cholecystectomy
    B Tang
    Surgical Skills Unit, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland
    Arch Surg 139:1215-20. 2004
    ..Surgical operative performance benefits from analysis of the mechanisms underlying technical errors committed during surgery...
  100. pmc Microencapsulation of human cells: its effects on growth of normal and tumour cells in vitro
    S M Shimi
    Department of Surgery, University of Dundee, Ninewells Hospital and Medical School, UK
    Br J Cancer 63:675-80. 1991
    ..We conclude that the use of microcapsules provides an alternative system with some advantages for the study of human cancer and its metastases in vitro...