H V Curran

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Older adults and withdrawal from benzodiazepine hypnotics in general practice: effects on cognitive function, sleep, mood and quality of life
    H V Curran
    Psychopharmacology Research Unit, Clinical Health Psychology, University College London
    Psychol Med 33:1223-37. 2003
  2. ncbi request reprint Quitting ecstasy: an investigation of why people stop taking the drug and their subsequent mental health
    Suzanne L Verheyden
    Clinical Psychopharmacology Unit, Clinical Health Psychology, University College London, London, UK
    J Psychopharmacol 17:371-8. 2003
  3. ncbi request reprint Neurocognitive function in current and ex-users of ecstasy in comparison to both matched polydrug-using controls and drug-naïve controls
    Rosa Hoshi
    Clinical Psychopharmacology Unit, Sub Department of Clinical Health Psychology, University College London, Gower Street, London, WC1E 6BT, UK
    Psychopharmacology (Berl) 194:371-9. 2007
  4. ncbi request reprint Mood and cognitive effects of +/-3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy'): week-end 'high' followed by mid-week low
    H V Curran
    Department of Psychology, University College London, UK
    Addiction 92:821-31. 1997
  5. ncbi request reprint Eating attitudes, weight concerns and beliefs about drug effects in women who use ecstasy
    H Valerie Curran
    Clinical Psychopharmacology Unit, University College London, Gower Street, London WC1E 6BT, UK
    J Psychopharmacol 20:425-31. 2006
  6. ncbi request reprint Empathy and aggression: two faces of ecstasy? A study of interpretative cognitive bias and mood change in ecstasy users
    H Valerie Curran
    Clinical Psychopharmacology Unit, University College London, Gower Street, London, WC1 6BT, UK
    Psychopharmacology (Berl) 173:425-33. 2004
  7. ncbi request reprint Altered response to tryptophan supplementation after long-term abstention from MDMA (ecstasy) is highly correlated with human memory function
    H Valerie Curran
    Clinical Psychopharmacology Unit, Clinical Health Psychology, University College London, Gower Street, London, WC1 6BT, UK
    Psychopharmacology (Berl) 169:91-103. 2003
  8. ncbi request reprint Cognitive and subjective dose-response effects of acute oral Delta 9-tetrahydrocannabinol (THC) in infrequent cannabis users
    H Valerie Curran
    Psychopharmacology Laboratories, Clinical Health Psychology, University College London, Gower Street, London WC1 6BT, UK
    Psychopharmacology (Berl) 164:61-70. 2002
  9. ncbi request reprint In and out of the K-hole: a comparison of the acute and residual effects of ketamine in frequent and infrequent ketamine users
    H V Curran
    Psychopharmacology Research Unit, Sub Department of Clinical Health Psychology, University College London, London, UK
    Addiction 96:749-60. 2001
  10. ncbi request reprint Effects of methadone on cognition, mood and craving in detoxifying opiate addicts: a dose-response study
    H V Curran
    Psychopharmacology Research Unit, Clinical Health Psychology, University College London, UK
    Psychopharmacology (Berl) 154:153-60. 2001

Detail Information

Publications65

  1. ncbi request reprint Older adults and withdrawal from benzodiazepine hypnotics in general practice: effects on cognitive function, sleep, mood and quality of life
    H V Curran
    Psychopharmacology Research Unit, Clinical Health Psychology, University College London
    Psychol Med 33:1223-37. 2003
    ..This study therefore aimed to determine if withdrawing from BZDs leads to changes in patients' cognitive function, quality of life, mood and sleep...
  2. ncbi request reprint Quitting ecstasy: an investigation of why people stop taking the drug and their subsequent mental health
    Suzanne L Verheyden
    Clinical Psychopharmacology Unit, Clinical Health Psychology, University College London, London, UK
    J Psychopharmacol 17:371-8. 2003
    ..The present study shows that some ex-users experience an impairment to mental health that persists for years after they stop using this drug...
  3. ncbi request reprint Neurocognitive function in current and ex-users of ecstasy in comparison to both matched polydrug-using controls and drug-naïve controls
    Rosa Hoshi
    Clinical Psychopharmacology Unit, Sub Department of Clinical Health Psychology, University College London, Gower Street, London, WC1E 6BT, UK
    Psychopharmacology (Berl) 194:371-9. 2007
    ..Attempting to reduce methodological problems, such as concurrent use of other recreational drugs, could lead to a clearer picture of the effects of ecstasy use on cognitive function...
  4. ncbi request reprint Mood and cognitive effects of +/-3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy'): week-end 'high' followed by mid-week low
    H V Curran
    Department of Psychology, University College London, UK
    Addiction 92:821-31. 1997
    ..Recreational use of +/-3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') is widespread. The present study aimed to examine both the acute and residual effects of this drug on users' mood and cognitive function...
  5. ncbi request reprint Eating attitudes, weight concerns and beliefs about drug effects in women who use ecstasy
    H Valerie Curran
    Clinical Psychopharmacology Unit, University College London, Gower Street, London WC1E 6BT, UK
    J Psychopharmacol 20:425-31. 2006
    ..However, our findings indicated that women are not using ecstasy as a deliberate means of weight control...
  6. ncbi request reprint Empathy and aggression: two faces of ecstasy? A study of interpretative cognitive bias and mood change in ecstasy users
    H Valerie Curran
    Clinical Psychopharmacology Unit, University College London, Gower Street, London, WC1 6BT, UK
    Psychopharmacology (Berl) 173:425-33. 2004
    ....
  7. ncbi request reprint Altered response to tryptophan supplementation after long-term abstention from MDMA (ecstasy) is highly correlated with human memory function
    H Valerie Curran
    Clinical Psychopharmacology Unit, Clinical Health Psychology, University College London, Gower Street, London, WC1 6BT, UK
    Psychopharmacology (Berl) 169:91-103. 2003
    ..This raises the question of whether long lasting effects occur in human beings that persist even after they have stopped using MDMA...
  8. ncbi request reprint Cognitive and subjective dose-response effects of acute oral Delta 9-tetrahydrocannabinol (THC) in infrequent cannabis users
    H Valerie Curran
    Psychopharmacology Laboratories, Clinical Health Psychology, University College London, Gower Street, London WC1 6BT, UK
    Psychopharmacology (Berl) 164:61-70. 2002
    ....
  9. ncbi request reprint In and out of the K-hole: a comparison of the acute and residual effects of ketamine in frequent and infrequent ketamine users
    H V Curran
    Psychopharmacology Research Unit, Sub Department of Clinical Health Psychology, University College London, London, UK
    Addiction 96:749-60. 2001
    ..To explore whether such persisting effects reflect chronic effects of ketamine use, the present study compared frequent with infrequent users of ketamine on the night of drug use and again 3 days later...
  10. ncbi request reprint Effects of methadone on cognition, mood and craving in detoxifying opiate addicts: a dose-response study
    H V Curran
    Psychopharmacology Research Unit, Clinical Health Psychology, University College London, UK
    Psychopharmacology (Berl) 154:153-60. 2001
    ..Objective: The present study aimed to assess the acute effects of methadone in patients admitted to an opiate detoxification programme...
  11. ncbi request reprint Is MDMA ('Ecstasy') neurotoxic in humans? An overview of evidence and of methodological problems in research
    H V Curran
    Department of Psychology, University College London, UK
    Neuropsychobiology 42:34-41. 2000
    ..These issues are critically discussed within the context of the wide-ranging methodological problems in human research with MDMA...
  12. ncbi request reprint Dissociative effects of alcohol on recollective experience
    H V Curran
    Department of Psychology, University College London, United Kingdom
    Conscious Cogn 8:497-509. 1999
    ..That both alcohol and depth of processing produce dissociative effects on recollective experience provides further evidence that remembering and knowing reflect distinct memory systems...
  13. ncbi request reprint Additional methadone increases craving for heroin: a double-blind, placebo-controlled study of chronic opiate users receiving methadone substitution treatment
    H V Curran
    Department of Psychology, University College London, UK
    Addiction 94:665-74. 1999
    ..To assess the acute-on-chronic effects of methadone on drug craving, mood and cognitive and psychomotor functioning in patients on long-term methadone substitution treatment...
  14. ncbi request reprint Cognitive, dissociative and psychotogenic effects of ketamine in recreational users on the night of drug use and 3 days later
    H V Curran
    Department of Psychology, University College London, UK
    Addiction 95:575-90. 2000
    ..The present study aimed to examine both the acute and residual effects of this drug on cognitive function, dissociation and schizotypal symptomatology in recreational users...
  15. doi request reprint Neurocognitive function and schizophrenia-proneness in individuals dependent on ketamine, on high potency cannabis ('skunk') or on cocaine
    C J A Morgan
    Clinical Psychopharmacology Unit, Research Department of Clinical, Educational and Health Psychology, University College London, London, U K
    Pharmacopsychiatry 45:269-74. 2012
    ..Ketamine, psychostimulants and cannabis have all been associated with psychotic phenomena but no study has directly compared users of these drugs...
  16. doi request reprint Drug cue induced overshadowing: selective disruption of natural reward processing by cigarette cues amongst abstinent but not satiated smokers
    T P Freeman
    Clinical Psychopharmacology Unit, Clinical Health Psychology, University College London, London, UK
    Psychol Med 42:161-71. 2012
    ..Similarly, blocking, a demonstration that learning depends on prediction error, can be influenced by the salience of the cues employed...
  17. doi request reprint The incidence of unpleasant dreams after sub-anaesthetic ketamine
    Mark Blagrove
    Department of Psychology, Swansea University, Swansea, SA2 8PP, UK
    Psychopharmacology (Berl) 203:109-20. 2009
    ....
  18. ncbi request reprint The effects of immediate-release morphine on cognitive functioning in patients receiving chronic opioid therapy in palliative care
    Sunjeev K Kamboj
    Clinical Psychopharmacology Unit, Sub Department of Clinical Health Psychology, University College London, Gower Street, London, WC1E 6BT, UK
    Pain 117:388-95. 2005
    ..These impairments may impact negatively on patients' everyday functioning...
  19. doi request reprint Acute effects of opioids on memory functions of healthy men and women
    James Friswell
    Clinical Psychopharmacology Unit, Clinical Health Psychology, University College London, Gower St, London WC1E 6BT, UK
    Psychopharmacology (Berl) 198:243-50. 2008
    ..However, both anterograde and retrograde memory impairments have been reported following an acute dose of morphine in palliative care patients (Kamboj et al., Pain 117:388-395, 2005)...
  20. doi request reprint Journey through the K-hole: phenomenological aspects of ketamine use
    L Muetzelfeldt
    Clinical Psychopharmacology Unit, University College London, Gower Street, London WC1E 6BT, United Kingdom
    Drug Alcohol Depend 95:219-29. 2008
    ..Additionally, the dependence on ketamine frequently reported by users may be a cause for concern as its popularity grows and substance misuse services should be made aware of this when clients present in the future...
  21. doi request reprint An experimental study of aggressive and neutral interpretative bias in opiate-dependent and opiate-abstinent men
    J Clair
    Clinical Psychopharmacology Unit, University College London, London, UK
    J Psychopharmacol 23:428-35. 2009
    ..Decreased testosterone levels associated with chronic opiate use may underpin this neutral bias...
  22. ncbi request reprint Ecstasy (MDMA) does not have long-term effects on aggressive interpretative bias: a study comparing current and ex-ecstasy users with polydrug and drug-naive controls
    Rosa Hoshi
    Clinical Psychopharmacology Unit, University College London, London, United Kingdom
    Exp Clin Psychopharmacol 15:351-8. 2007
    ....
  23. doi request reprint Acute effects of alcohol on memory: impact of emotional context and serial position
    Jennie Brown
    Psychopharmacology Unit, Research Department of Clinical, Educational and Health Psychology, University College London, Gower Street, London WC1E6BT, United Kingdom
    Neurobiol Learn Mem 93:428-34. 2010
    ..The results suggest that under certain circumstances emotional context or physiological arousal make memories labile and susceptible to disruption through pharmacological manipulation during encoding...
  24. ncbi request reprint A comparison of the effects of a beta-adrenergic blocker and a benzodiazepine upon the recognition of human facial expressions
    Andrea Zangara
    Department of Psychology, University College London, Gower Street, London WC1H 6BT, UK
    Psychopharmacology (Berl) 163:36-41. 2002
    ..Recent evidence implies that the processing of different facial expressions may also be dissociable pharmacologically by GABAergic and noradrenergic compounds, although no study has directly compared the two types of drugs...
  25. doi request reprint Attentional bias to incentive stimuli in frequent ketamine users
    C J A Morgan
    Clinical Psychopharmacology Unit, University College London, London, UK
    Psychol Med 38:1331-40. 2008
    ..Dependence on ketamine has been reported anecdotally but no systematic study has investigated this phenomenon. We aimed to explore attentional biases to incentive stimuli in different populations of ketamine users...
  26. doi request reprint Global impairment of prospective memory following acute alcohol
    Julie R Leitz
    Clinical Psychopharmacology Unit, Clinical Psychology, University College London, Gower St, London WC1E 6BT, UK
    Psychopharmacology (Berl) 205:379-87. 2009
    ..Whilst the deleterious effects of alcohol on retrospective remembering have been widely documented, no study has yet objectively determined alcohol's effects on prospective memory (PM)--remembering to do something in the future...
  27. doi request reprint Drinking and future thinking: acute effects of alcohol on prospective memory and future simulation
    Theadora Paraskevaides
    Clinical Psychopharmacology Unit, Research Department of Clinical, Health and Educational Psychology, University College London, Gower St, London, WC1E 6BT, UK
    Psychopharmacology (Berl) 208:301-8. 2010
    ..in Psychopharmacology 205:379-387, 2009). In healthy, sober individuals, simulating future events at encoding enhances PM performance...
  28. ncbi request reprint Scopolamine induces impairments in the recognition of human facial expressions of anger and disgust
    S K Kamboj
    Clinical Psychopharmacology Unit, Sub Department of Clinical Health Psychology, University College London, Gower Street, London, WC1E 6BT, UK
    Psychopharmacology (Berl) 185:529-35. 2006
    ..However, it is unclear if these impairments are a general property of benzodiazepines and other drugs that produce a similar profile of neurocognitive impairment to benzodiazepines, such as the anticholinergic, scopolamine...
  29. ncbi request reprint Selective impairment in the recognition of anger induced by diazepam
    R J Blair
    Institute of Cognitive Neuroscience, London, UK
    Psychopharmacology (Berl) 147:335-8. 1999
    ..Given this functional specialization of expression processing, it is plausible that these neurocognitive systems may also be dissociable pharmacologically...
  30. ncbi request reprint Managing constraint: the experience of people with chronic pain
    A Miles
    Department of Psychology, University College London, Gower Street, London WC1E 6BT, UK
    Soc Sci Med 61:431-41. 2005
    ....
  31. ncbi request reprint Attitudes to long-term use of benzodiazepine hypnotics by older people in general practice: findings from interviews with service users and providers
    S Iliffe
    Department of Primary Care and Population Sciences, Royal Free and UCL Medical School, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK
    Aging Ment Health 8:242-8. 2004
    ..Both increased patient awareness of the problems of long-term benzodiazepine use and an evidence-based approach to withdrawal efforts in primary care are necessary to reduce the consumption of medication that has little real benefit...
  32. pmc Is persistent ketamine use a valid model of the cognitive and oculomotor deficits in schizophrenia?
    Celia J A Morgan
    Clinical Psychopharmacology Unit, University College London, United Kingdom
    Biol Psychiatry 65:1099-102. 2009
    ..In this study, we investigated the effect of persistent recreational ketamine use on tests of episodic and working memory and on oculomotor tasks of smooth pursuit and pro- and antisaccades...
  33. doi request reprint Superstitious conditioning as a model of delusion formation following chronic but not acute ketamine in humans
    Tom P Freeman
    Clinical Psychopharmacology Unit, Clinical Health Psychology, University College London, Gower Street, London, UK
    Psychopharmacology (Berl) 206:563-73. 2009
    ..Delusions are theoretically underpinned by increased superstitious conditioning or the erroneous reinforcement of random events...
  34. doi request reprint Acute and chronic effects of ketamine on semantic priming: modeling schizophrenia?
    Ana Stefanovic
    Clinical Psychopharmacology Unit, University College London, London, United Kingdom
    J Clin Psychopharmacol 29:124-33. 2009
    ..In summary, acute and chronic ketamine-induced changes partially mirrored the findings on semantic priming in schizophrenia...
  35. doi request reprint Can recreational doses of THC produce significant dopamine release in the human striatum?
    Paul R A Stokes
    Psychiatry Group, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital Campus, London, UK
    Neuroimage 48:186-90. 2009
    ..In animals, Delta9-tetrahydrocannabinol (THC) increases the rate of dopamine neuronal firing and release in the striatum. Thus cannabis use may increase dopamine release in the human striatum leading to vulnerability to psychosis...
  36. pmc Encoding of marginal utility across time in the human brain
    Alex Pine
    Wellcome Trust Centre for Neuroimaging, London, United Kingdom
    J Neurosci 29:9575-81. 2009
    ..Our data support an integrative architecture for decision making, revealing the neural representation of distinct subcomponents of value that may contribute to impulsivity and decisiveness...
  37. doi request reprint Decreases in recollective experience following acute alcohol: a dose-response study
    James A Bisby
    Clinical Psychopharmacology Unit, University College London, Gower Street, London, UK
    Psychopharmacology (Berl) 208:67-74. 2010
    ..Acute alcohol intoxication induces a selective impairment of recognition memory associated with conscious recollection whilst recognition based on familiarity is left intact...
  38. doi request reprint Consequences of chronic ketamine self-administration upon neurocognitive function and psychological wellbeing: a 1-year longitudinal study
    Celia J A Morgan
    Clinical Psychopharmacology Unit, Clinical Health Psychology, University College London, London, UK
    Addiction 105:121-33. 2010
    ..In healthy individuals an acute dose of the N-methyl D-aspartate (NMDA) receptor antagonist ketamine induces marked psychosis-like effects and cognitive impairments, but little is known about the long-term effects of the drug...
  39. doi request reprint Harms associated with psychoactive substances: findings of the UK National Drug Survey
    Celia J A Morgan
    Clinical Psychopharmacology Unit, University College London, London, UK
    J Psychopharmacol 24:147-53. 2010
    ..They also suggest that the current UK legal classification system is not acting to inform users of the harms of psychoactive substances...
  40. doi request reprint Hyper-priming in cannabis users: a naturalistic study of the effects of cannabis on semantic memory function
    Celia J A Morgan
    Clinical Psychopharmacology Unit, Sub Department of Clinical Health Psychology, University College London, Gower St, London, WC1E 6BT, United Kingdom
    Psychiatry Res 176:213-8. 2010
    ..The acute increase in automatic semantic priming may be one factor contributing to the psychotomimetic effects of cannabis...
  41. doi request reprint Acute effects of alcohol on intrusive memory development and viewpoint dependence in spatial memory support a dual representation model
    James A Bisby
    Clinical Psychopharmacology Unit, University College London, United Kingdom
    Biol Psychiatry 68:280-6. 2010
    ..We tested the model by investigating the effect of alcohol on intrusive memories and, concurrently, on egocentric and allocentric spatial memory...
  42. pmc Cannabidiol attenuates the appetitive effects of Delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis
    Celia J A Morgan
    Clinical Psychopharmacology Unit, Research Department of Clinical, Health and Educational Psychology, University College London, London, UK
    Neuropsychopharmacology 35:1879-85. 2010
    ..Our findings suggest that CBD has potential as a treatment for cannabis dependence. The acute modulation of the incentive salience of drug cues by CBD may possibly generalize to a treatment for other addictive disorders...
  43. doi request reprint Ketamine use, cognition and psychological wellbeing: a comparison of frequent, infrequent and ex-users with polydrug and non-using controls
    Celia J A Morgan
    Clinical Psychopharmacology Unit, University College London, London, UK
    Addiction 104:77-87. 2009
    ..In this study we aimed to determine how variations in ketamine use and abstention from prior use affect neurocognitive function and psychological wellbeing...
  44. doi request reprint The psychotomimetic states inventory (PSI): measuring psychotic-type experiences from ketamine and cannabis
    Oliver J Mason
    Sub Department of Clinical Health Psychology, University College London, Gower Street, London WC1E 6BT, United Kingdom
    Schizophr Res 103:138-42. 2008
    ..The Psychotomimetic States Inventory (PSI) has sub-scales of Delusory Thinking, Perceptual Distortions, Cognitive Disorganization, Anhedonia, Mania and Paranoia...
  45. doi request reprint Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis
    Celia J A Morgan
    Clinical Psychopharmacology Unit, Sub Department of Clinical Health Psychology, University College London, London, UK
    Br J Psychiatry 192:306-7. 2008
    ..This provides evidence of the divergent properties of cannabinoids and has important implications for research into the link between cannabis use and psychosis...
  46. ncbi request reprint Acute, sub-acute and long-term subjective consequences of 'ecstasy' (MDMA) consumption in 430 regular users
    Suzanne L Verheyden
    Clinical Psychopharmacology Unit, Clinical Health Psychology, University College London, Gower Street, London WC1E 6BT, UK
    Hum Psychopharmacol 18:507-17. 2003
    ..In terms of what might persuade users to stop using MDMA, their most prominent concern was the drug's long-term effects on mental health...
  47. ncbi request reprint Acute effects of ketamine on memory systems and psychotic symptoms in healthy volunteers
    Celia J A Morgan
    Clinical Psychopharmacology Unit, Sub Department of Clinical Health Psychology, University College London, London, England
    Neuropsychopharmacology 29:208-18. 2004
    ..These data suggest that, in humans, ketamine produces a selective pattern of impairments to working, episodic, and procedural memory but not to perceptual priming, attention or aspects of executive functioning...
  48. ncbi request reprint Long-term effects of ketamine: evidence for a persisting impairment of source memory in recreational users
    Celia J A Morgan
    Clinical Psychopharmacology Unit, Clinical Health Psychology, University College London, Gower St, London WC1E 6BT, UK
    Drug Alcohol Depend 75:301-8. 2004
    ..Previous research has shown gross generalised verbal memory impairments persisting 3 days after ketamine use in chronic users, however episodic memory has not specifically investigated in this population...
  49. ncbi request reprint Beyond the K-hole: a 3-year longitudinal investigation of the cognitive and subjective effects of ketamine in recreational users who have substantially reduced their use of the drug
    Celia J A Morgan
    Clinical Psychopharmacology Unit, University College London, London, UK
    Addiction 99:1450-61. 2004
    ..However, the degree to which these deficits might be reversible upon reduction or cessation of ketamine use was not known...
  50. ncbi request reprint The acute and sub-acute effects of 'ecstasy' (MDMA) on processing of facial expressions: preliminary findings
    Rosa Hoshi
    Clinical Psychopharmacology Unit, Sub Department of Clinical Health Psychology, University College London, Gower Street, London WC1E 6BT, UK
    Drug Alcohol Depend 76:297-304. 2004
    ..It is therefore possible that the recreational drug 'ecstasy' (MDMA), which has marked serotonergic effects, may affect people's ability to recognise human facial expressions portraying fear...
  51. ncbi request reprint Disruption of sequential priming in organic and pharmacological amnesia: a role for the medial temporal lobes in implicit contextual learning
    David R Shanks
    Department of Psychology, University College London, London, UK
    Neuropsychopharmacology 31:1768-76. 2006
    ..The results suggest that a function of the hippocampal memory system is to support contextual learning and performance, even when that learning is nondeclarative...
  52. ncbi request reprint An investigation into the sub-acute effects of ecstasy on aggressive interpretative bias and aggressive mood - are there gender differences?
    Rosa Hoshi
    Clinical Psychopharmacology Unit, University College London, UK
    J Psychopharmacol 20:291-301. 2006
    ..Both male and female ecstasy users show a bias toward interpretation of ambiguous material in an aggressive manner when compared to controls 4 days after ecstasy use...
  53. ncbi request reprint Acute and chronic effects of ketamine upon human memory: a review
    Celia J A Morgan
    Clinical Psychopharmacology Unit, Sub Department of Clinical Health Psychology, University College London, Gower Street, London, WC1E 6BT, UK
    Psychopharmacology (Berl) 188:408-24. 2006
    ..Ketamine is attracting increasing research interest not only because of its powerful amnestic effects but also as a putative model of schizophrenia and as a substance with an expanding following of recreational users...
  54. ncbi request reprint Ketamine impairs response inhibition and is positively reinforcing in healthy volunteers: a dose-response study
    Celia J A Morgan
    Clinical Psychopharmacology Unit, Sub Department of Clinical Health Psychology, University College London, Gower St, London, WC1E 6BT, UK
    Psychopharmacology (Berl) 172:298-308. 2004
    ..Previous research has found persisting cognitive and psychotogenic effects of ketamine in chronic abusers of this drug 3 days after an acute dose...
  55. ncbi request reprint Semantic priming after ketamine acutely in healthy volunteers and following chronic self-administration in substance users
    Celia J A Morgan
    Clinical Psychopharmacology Unit, University College London, London WC1E 6BT, United Kingdom
    Biol Psychiatry 59:265-72. 2006
    ..As semantic processing deficits are considered central to cognitive impairments in schizophrenia, this study aimed to characterize semantic impairments following both acute and chronic ketamine...
  56. ncbi request reprint Neutral and emotional episodic memory: global impairment after lorazepam or scopolamine
    Sunjeev K Kamboj
    Clinical Psychopharmacology Unit, Sub Department of Clinical Health Psychology, University College London, London, WC1E 6BT, UK
    Psychopharmacology (Berl) 188:482-8. 2006
    ..Benzodiazepines and anticholinergic drugs have repeatedly been shown to impair episodic memory for emotionally neutral material in humans. However, their effect on memory for emotionally laden stimuli has been relatively neglected...
  57. doi request reprint Acute cannabis use causes increased psychotomimetic experiences in individuals prone to psychosis
    O Mason
    Clinical Psychopharmacology Unit, University College London, London, UK
    Psychol Med 39:951-6. 2009
    ..We hypothesized that highly psychosis-prone individuals would report more marked psychotic experiences under the acute influence of cannabis...
  58. ncbi request reprint Sub-acute effects of MDMA (+/-3,4-methylenedioxymethamphetamine, "ecstasy") on mood: evidence of gender differences
    Suzanne L Verheyden
    Psychopharmacology Laboratories, Sub Department of Clinical Health Psychology, University College London, Gower Street, London WC1E 6BT, UK
    Psychopharmacology (Berl) 161:23-31. 2002
    ..If the same is true in humans, then functions thought to be modulated by 5-HT may differ in MDMA users compared with non-users a few days after the drug is taken...
  59. doi request reprint Attentional bias, inhibitory control and acute stress in current and former opiate addicts
    Natasha Constantinou
    Clinical Psychopharmacology Unit, University College London, United Kingdom
    Drug Alcohol Depend 109:220-5. 2010
    ..Although acute stress is known to increase craving, it is not known whether this effect is mediated via changes in attentional bias and inhibitory control...
  60. ncbi request reprint Enhanced recognition of facial expressions of disgust in opiate users receiving maintenance treatment
    Louise Martin
    Clinical Psychopharmacology Unit, UCL, London, UK
    Addiction 101:1598-605. 2006
    ..Little is known of whether other drug-dependent populations also show these impairments. This study aimed to investigate facial expression recognition by chronic opiate users...
  61. ncbi request reprint Pharmacological manipulations of arousal and memory for emotional material: effects of a single dose of methylphenidate or lorazepam
    Catherine M Brignell
    School of Psychology, University of Southampton, Southampton, UK
    J Psychopharmacol 21:673-83. 2007
    ..The effects of Lorazepam add to a growing literature that benzodiazepines may exert their clinical, anxiolytic effects in part via altering emotionaL cognitive function...
  62. ncbi request reprint Perceptual organization in ketamine users: preliminary evidence of deficits on night of drug use but not 3 days later
    Peter J Uhlhaas
    Max Planck Institute for Brain Research, Frankfurt, Germany
    J Psychopharmacol 21:347-52. 2007
    ..Levels of dissociation were also higher in ketamine users only on the night of drug use. These preliminary data provide some support for the role of NMDA-receptor hypofunctioning in dysfunctional coordination of cognitive activity...
  63. ncbi request reprint Angry cognitive bias, trait aggression and impulsivity in substance users
    Alyson J Bond
    National Addiction Centre, Institute of Psychiatry, Kings College London, De Crespigny Park, UK
    Psychopharmacology (Berl) 171:331-9. 2004
    ..This may relate to low 5-HT release, and so a 5-HT challenge may increase cognitive bias towards anger differentially in MDMA users and non-users...
  64. ncbi request reprint Drugs, sweat, and fears: a comparison of the effects of diazepam and methylphenidate on fear conditioning
    Catherine M Brignell
    School of Psychology, University of Southampton, Highfield, Southampton, SO17 1BJ, UK
    Psychopharmacology (Berl) 186:504-16. 2006
    ..While both benzodiazepines and stimulant drugs may influence the formation of episodic memories for emotional events, their effects on fear conditioning are less clear...
  65. ncbi request reprint Psychopharmacology of memory
    H Valerie Curran
    Psychopharmacology (Berl) 188:393-6. 2006