Stuart M Curbishley

Summary

Affiliation: University of Birmingham
Country: UK

Publications

  1. pmc CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow
    Stuart M Curbishley
    Liver Research Group, Institute of Biomedical Research, MRC Centre for Immune Regulation, The University of Birmingham Medical School, Edgbaston, Birmingham, UK B15 2TT
    Am J Pathol 167:887-99. 2005
  2. pmc Identification of distinct human invariant natural killer T-cell response phenotypes to alpha-galactosylceramide
    Joanne E Croudace
    MRC Centre for Immune Regulation, University of Birmingham, Birmingham B15 2TT, UK
    BMC Immunol 9:71. 2008
  3. ncbi request reprint Identifying homing interactions in T-cell traffic in human disease
    Patricia F Lalor
    Liver Research Group, Division of Medicine, Institute of Biomedical Research, MRC Centre for Immune Regulation, University of Birmingham, Birmingham, UK
    Methods Mol Biol 616:231-52. 2010
  4. pmc Activation of CD40 with platelet derived CD154 promotes reactive oxygen species dependent death of human hepatocytes during hypoxia and reoxygenation
    Ricky H Bhogal
    Centre for Liver Research, School of Infection and Immunity, Institute of Biomedical Research, The Medical School, The University of Birmingham, Edgbaston, Birmingham, United Kingdom
    PLoS ONE 7:e30867. 2012
  5. pmc Isolation of primary human hepatocytes from normal and diseased liver tissue: a one hundred liver experience
    Ricky H Bhogal
    Centre for Liver Research, Institute for Biomedical Research, University of Birmingham, Edgbaston, Birmingham, United Kingdom
    PLoS ONE 6:e18222. 2011
  6. pmc Gut homing receptors on CD8 T cells are retinoic acid dependent and not maintained by liver dendritic or stellate cells
    Bertus Eksteen
    MRC Centre for Immune Regulation, Institute for Biomedical Research, Medical School, University of Birmingham, Birmingham, United Kingdom
    Gastroenterology 137:320-9. 2009
  7. ncbi request reprint Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver
    Ye H Oo
    Centre for Liver Research, Institute of Biomedical Research, The University of Birmingham Medical School, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom
    J Immunol 184:2886-98. 2010
  8. pmc Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics
    Evaggelia Liaskou
    Centre for Liver Research and NIHR Biomedical Research Unit in Liver Disease, Institute of Biomedical Research, University of Birmingham, Birmingham, United Kingdom
    Hepatology 57:385-98. 2013
  9. ncbi request reprint A new approach to isolation and culture of human Kupffer cells
    Edward B Alabraba
    Liver Research Group, 5th Floor IBR, The University of Birmingham Medical School, Wolfson Drive, Edgbaston, Birmingham B152TT, UK
    J Immunol Methods 326:139-44. 2007
  10. pmc Variable responses of small and large human hepatocytes to hypoxia and hypoxia/reoxygenation (H-R)
    Ricky H Bhogal
    Centre for Liver Research, School of Infection and Immunity, Institute of Biomedical Research, The Medical School, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    FEBS Lett 585:935-41. 2011

Detail Information

Publications13

  1. pmc CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow
    Stuart M Curbishley
    Liver Research Group, Institute of Biomedical Research, MRC Centre for Immune Regulation, The University of Birmingham Medical School, Edgbaston, Birmingham, UK B15 2TT
    Am J Pathol 167:887-99. 2005
    ....
  2. pmc Identification of distinct human invariant natural killer T-cell response phenotypes to alpha-galactosylceramide
    Joanne E Croudace
    MRC Centre for Immune Regulation, University of Birmingham, Birmingham B15 2TT, UK
    BMC Immunol 9:71. 2008
    ....
  3. ncbi request reprint Identifying homing interactions in T-cell traffic in human disease
    Patricia F Lalor
    Liver Research Group, Division of Medicine, Institute of Biomedical Research, MRC Centre for Immune Regulation, University of Birmingham, Birmingham, UK
    Methods Mol Biol 616:231-52. 2010
    ..Although our own experience is with human liver tissue, the general principles apply to analysing any organ of interest...
  4. pmc Activation of CD40 with platelet derived CD154 promotes reactive oxygen species dependent death of human hepatocytes during hypoxia and reoxygenation
    Ricky H Bhogal
    Centre for Liver Research, School of Infection and Immunity, Institute of Biomedical Research, The Medical School, The University of Birmingham, Edgbaston, Birmingham, United Kingdom
    PLoS ONE 7:e30867. 2012
    ..We hypothesised that CD40 activation and ROS accumulation act synergistically to drive human hepatocyte apoptosis...
  5. pmc Isolation of primary human hepatocytes from normal and diseased liver tissue: a one hundred liver experience
    Ricky H Bhogal
    Centre for Liver Research, Institute for Biomedical Research, University of Birmingham, Edgbaston, Birmingham, United Kingdom
    PLoS ONE 6:e18222. 2011
    ....
  6. pmc Gut homing receptors on CD8 T cells are retinoic acid dependent and not maintained by liver dendritic or stellate cells
    Bertus Eksteen
    MRC Centre for Immune Regulation, Institute for Biomedical Research, Medical School, University of Birmingham, Birmingham, United Kingdom
    Gastroenterology 137:320-9. 2009
    ....
  7. ncbi request reprint Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver
    Ye H Oo
    Centre for Liver Research, Institute of Biomedical Research, The University of Birmingham Medical School, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom
    J Immunol 184:2886-98. 2010
    ..Thus, different chemokine receptors play distinct roles in the recruitment and positioning of T(regs) at sites of hepatitis in chronic liver disease...
  8. pmc Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics
    Evaggelia Liaskou
    Centre for Liver Research and NIHR Biomedical Research Unit in Liver Disease, Institute of Biomedical Research, University of Birmingham, Birmingham, United Kingdom
    Hepatology 57:385-98. 2013
    ....
  9. ncbi request reprint A new approach to isolation and culture of human Kupffer cells
    Edward B Alabraba
    Liver Research Group, 5th Floor IBR, The University of Birmingham Medical School, Wolfson Drive, Edgbaston, Birmingham B152TT, UK
    J Immunol Methods 326:139-44. 2007
    ....
  10. pmc Variable responses of small and large human hepatocytes to hypoxia and hypoxia/reoxygenation (H-R)
    Ricky H Bhogal
    Centre for Liver Research, School of Infection and Immunity, Institute of Biomedical Research, The Medical School, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    FEBS Lett 585:935-41. 2011
    ..This increased ROS regulates hepatocyte apoptosis and necrosis via a mitochondrial pathway. These findings have implications on the understanding of liver injury and application of potential therapeutic strategies...
  11. ncbi request reprint Hepatitis C is associated with perturbation of intrahepatic myeloid and plasmacytoid dendritic cell function
    Wai Kwan Lai
    Liver Research Group, Institute of Biomedical Research, The University of Birmingham Medical School, Wolfson Drive, Edgbaston, Birmingham B15 2TT, UK
    J Hepatol 47:338-47. 2007
    ..The suggestion that dendritic cells are defective in chronic HCV infection led us to investigate the phenotype and function of liver-derived myeloid (mDC) and plasmacytoid (pDC) dendritic cells in patients with chronic HCV infection...
  12. ncbi request reprint Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10
    Bertus Eksteen
    Liver Research Laboratories, Medical Research Council for Immune Regulation, Institute for Biomedical Research, University of Birmingham, Birmingham B15 2TH, UK
    J Immunol 177:593-603. 2006
    ..We propose that CXCR3 promotes the recruitment of Tregs to inflamed tissues and CCR10 allows them to respond to CCL28 secreted by epithelial cells resulting in the accumulation of CCR10+ Tregs at mucosal surfaces...
  13. pmc Hepatic endothelial CCL25 mediates the recruitment of CCR9+ gut-homing lymphocytes to the liver in primary sclerosing cholangitis
    Bertus Eksteen
    Liver Research Laboratories, Institute for Biomedical Research, University of Birmingham, Queen Elizabeth Hospital, Birmingham B15 2TT, England, UK
    J Exp Med 200:1511-7. 2004
    ..This is the first demonstration in humans that T cells activated in the gut can be recruited to an extra-intestinal site of disease and provides a paradigm to explain the pathogenesis of extra-intestinal complications of IBD...