Colin M Crump

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Alphaherpesvirus glycoprotein M causes the relocalization of plasma membrane proteins
    Colin M Crump
    Division of Virology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK
    J Gen Virol 85:3517-27. 2004
  2. pmc Herpes simplex virus type 1 cytoplasmic envelopment requires functional Vps4
    Colin M Crump
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    J Virol 81:7380-7. 2007
  3. doi request reprint Glycoprotein M is important for the efficient incorporation of glycoprotein H-L into herpes simplex virus type 1 particles
    Yudan Ren
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    J Gen Virol 93:319-29. 2012
  4. pmc Analysis of Rab GTPase-activating proteins indicates that Rab1a/b and Rab43 are important for herpes simplex virus 1 secondary envelopment
    Helen L Zenner
    Division of Virology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK
    J Virol 85:8012-21. 2011
  5. pmc Herpes simplex virus 1 counteracts tetherin restriction via its virion host shutoff activity
    Helen L Zenner
    Department of Pathology, University of Cambridge, Cambridge, United Kingdom
    J Virol 87:13115-23. 2013
  6. pmc Analysis of the interaction between the essential herpes simplex virus 1 tegument proteins VP16 and VP1/2
    Stanislava Svobodova
    Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
    J Virol 86:473-83. 2012
  7. pmc Herpes simplex virus type 1 production requires a functional ESCRT-III complex but is independent of TSG101 and ALIX expression
    Tobias Pawliczek
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    J Virol 83:11254-64. 2009
  8. doi request reprint Budding of filamentous and non-filamentous influenza A virus occurs via a VPS4 and VPS28-independent pathway
    Emily A Bruce
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    Virology 390:268-78. 2009
  9. pmc Role of PACS-1 in trafficking of human cytomegalovirus glycoprotein B and virus production
    Colin M Crump
    Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Virol 77:11105-13. 2003
  10. pmc PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis
    Thomas Simmen
    Vollum Institute, Portland, OR 97239 3098, USA
    EMBO J 24:717-29. 2005

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Alphaherpesvirus glycoprotein M causes the relocalization of plasma membrane proteins
    Colin M Crump
    Division of Virology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK
    J Gen Virol 85:3517-27. 2004
    ..These data suggest that herpesvirus gM (gM/N) can alter the membrane trafficking itineraries of a broad range of proteins and this may have multiple functions...
  2. pmc Herpes simplex virus type 1 cytoplasmic envelopment requires functional Vps4
    Colin M Crump
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    J Virol 81:7380-7. 2007
    ..This is the first example of a large enveloped DNA virus engaging the multivesicular endosome sorting machinery to enable infectious virus production...
  3. doi request reprint Glycoprotein M is important for the efficient incorporation of glycoprotein H-L into herpes simplex virus type 1 particles
    Yudan Ren
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    J Gen Virol 93:319-29. 2012
    ..These data suggest an important role of gM in mediating the specific internalization and efficient targeting of gH-L to sites of secondary envelopment in infected cells...
  4. pmc Analysis of Rab GTPase-activating proteins indicates that Rab1a/b and Rab43 are important for herpes simplex virus 1 secondary envelopment
    Helen L Zenner
    Division of Virology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK
    J Virol 85:8012-21. 2011
    ....
  5. pmc Herpes simplex virus 1 counteracts tetherin restriction via its virion host shutoff activity
    Helen L Zenner
    Department of Pathology, University of Cambridge, Cambridge, United Kingdom
    J Virol 87:13115-23. 2013
    ..Taken together, our data suggest that tetherin has antiviral activity toward HSV-1 and that the removal of tetherin by Vhs is important for the efficient replication and dissemination of HSV-1. ..
  6. pmc Analysis of the interaction between the essential herpes simplex virus 1 tegument proteins VP16 and VP1/2
    Stanislava Svobodova
    Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
    J Virol 86:473-83. 2012
    ..These data also support the notion that the incorporation of tegument proteins into the herpesviruses is a very complex process with significant redundancy...
  7. pmc Herpes simplex virus type 1 production requires a functional ESCRT-III complex but is independent of TSG101 and ALIX expression
    Tobias Pawliczek
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    J Virol 83:11254-64. 2009
    ..In line with these data, we also find that ESCRT-III proteins and VPS4A/B are specifically incorporated into mature HSV-1 virions...
  8. doi request reprint Budding of filamentous and non-filamentous influenza A virus occurs via a VPS4 and VPS28-independent pathway
    Emily A Bruce
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    Virology 390:268-78. 2009
    ..Overall, we see no role for the ESCRT pathway in influenza virus budding and the significance of the M1-VPS28 interaction remains to be determined...
  9. pmc Role of PACS-1 in trafficking of human cytomegalovirus glycoprotein B and virus production
    Colin M Crump
    Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Virol 77:11105-13. 2003
    ....
  10. pmc PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis
    Thomas Simmen
    Vollum Institute, Portland, OR 97239 3098, USA
    EMBO J 24:717-29. 2005
    ..Together, our results identify PACS-2 as a novel sorting protein that links the ER-mitochondria axis to ER homeostasis and the control of cell fate, and provide new insights into Bid action...
  11. pmc The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic
    Gregory K Scott
    Vollum Institute, L 474, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    EMBO J 22:6234-44. 2003
    ..These results suggest that coordinated signaling events regulate transport within the TGN/endosomal system through the phosphorylation state of both cargo and the sorting machinery...