D A Cottrell

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. ncbi Role of mitochondrial DNA mutations in disease and aging
    D A Cottrell
    Department of Neurology, Medical School, University of Newcastle upon Tyne, UK
    Ann N Y Acad Sci 908:199-207. 2000
  2. ncbi Mitochondria and ageing
    D A Cottrell
    Department of Neurology, The Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH, UK
    Curr Opin Clin Nutr Metab Care 3:473-8. 2000
  3. ncbi Cytochrome c oxidase deficient cells accumulate in the hippocampus and choroid plexus with age
    D A Cottrell
    Department of Neurology, The Medical School, University of Newcastle upon Tyne, NE2 4HH, Newcastle upon Tyne, UK
    Neurobiol Aging 22:265-72. 2001
  4. ncbi Mitochondrial enzyme-deficient hippocampal neurons and choroidal cells in AD
    D A Cottrell
    Department of Neurology, The Medical School, University of Newcastle upon Tyne, UK
    Neurology 57:260-4. 2001
  5. ncbi The role of cytochrome c oxidase deficient hippocampal neurones in Alzheimer's disease
    D A Cottrell
    Department of Neurology, The Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Neuropathol Appl Neurobiol 28:390-6. 2002
  6. ncbi Mitochondrial DNA mutations in disease and ageing
    D A Cottrell
    Department of Neurology, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, NE2 4HH
    Novartis Found Symp 235:234-43; discussion 243-6. 2001
  7. ncbi Accelerated ageing changes in the choroid plexus of a case with multiple mitochondrial DNA deletions
    D A Cottrell
    Department of Neurology, The Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, NE2 4HH, UK
    Neuropathol Appl Neurobiol 27:206-14. 2001
  8. ncbi The mitochondrial genome, aging and neurodegenerative disorders
    D A Cottrell
    Department of Neurology, Medical School, University of Newcastle upon Tyne, UK
    Nestle Nutr Workshop Ser Clin Perform Programme 6:1-13; discussion 13-6. 2002

Collaborators

Detail Information

Publications8

  1. ncbi Role of mitochondrial DNA mutations in disease and aging
    D A Cottrell
    Department of Neurology, Medical School, University of Newcastle upon Tyne, UK
    Ann N Y Acad Sci 908:199-207. 2000
    ....
  2. ncbi Mitochondria and ageing
    D A Cottrell
    Department of Neurology, The Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH, UK
    Curr Opin Clin Nutr Metab Care 3:473-8. 2000
    ..Promising avenues for addressing this problem include the investigation of established mitochondrial DNA disorders and the development of animal models with mitochondrial defects...
  3. ncbi Cytochrome c oxidase deficient cells accumulate in the hippocampus and choroid plexus with age
    D A Cottrell
    Department of Neurology, The Medical School, University of Newcastle upon Tyne, NE2 4HH, Newcastle upon Tyne, UK
    Neurobiol Aging 22:265-72. 2001
    ..We suggest that these cells contribute to the cell death and dysfunction in CNS aging...
  4. ncbi Mitochondrial enzyme-deficient hippocampal neurons and choroidal cells in AD
    D A Cottrell
    Department of Neurology, The Medical School, University of Newcastle upon Tyne, UK
    Neurology 57:260-4. 2001
    ..To determine whether hippocampal neurons and choroidal epithelial cells demonstrate a mitochondrial enzyme deficiency in AD more frequently than in normal aging...
  5. ncbi The role of cytochrome c oxidase deficient hippocampal neurones in Alzheimer's disease
    D A Cottrell
    Department of Neurology, The Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Neuropathol Appl Neurobiol 28:390-6. 2002
    ....
  6. ncbi Mitochondrial DNA mutations in disease and ageing
    D A Cottrell
    Department of Neurology, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, NE2 4HH
    Novartis Found Symp 235:234-43; discussion 243-6. 2001
    ..Whether these mutations are a primary or secondary event in the physiology of ageing remains to be determined...
  7. ncbi Accelerated ageing changes in the choroid plexus of a case with multiple mitochondrial DNA deletions
    D A Cottrell
    Department of Neurology, The Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, NE2 4HH, UK
    Neuropathol Appl Neurobiol 27:206-14. 2001
    ..We believe that this finding supports the theory that the accumulation of mitochondrial DNA mutations can lead to pathological changes typical of ageing cells...
  8. ncbi The mitochondrial genome, aging and neurodegenerative disorders
    D A Cottrell
    Department of Neurology, Medical School, University of Newcastle upon Tyne, UK
    Nestle Nutr Workshop Ser Clin Perform Programme 6:1-13; discussion 13-6. 2002