M F Cordeiro

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi Neuroprotection in glaucoma - Is there a future role?
    Abeir Baltmr
    Glaucoma and Retinal Neurodegeneration Research Group, Visual Neurosciences Department, University College London Institute of Ophthalmology, Bath Street, London EC1V 9EL, United Kingdom
    Exp Eye Res 91:554-66. 2010
  2. ncbi Assessment of neuroprotection in the retina with DARC
    Li Guo
    Glaucoma and Retinal Degeneration Research Group, UCL Institute of Ophthalmology, London, UK
    Prog Brain Res 173:437-50. 2008
  3. ncbi TGF-beta1, -beta2, and -beta3 in vitro: biphasic effects on Tenon's fibroblast contraction, proliferation, and migration
    M F Cordeiro
    Department of Pathology, Moorfields Eye Hospital and Institute of Ophthalmology, London, United Kingdom
    Invest Ophthalmol Vis Sci 41:756-63. 2000
  4. ncbi Imaging multiple phases of neurodegeneration: a novel approach to assessing cell death in vivo
    M F Cordeiro
    UCL Institute of Ophthalmology, University College London, London, UK
    Cell Death Dis 1:e3. 2010
  5. ncbi Alzheimer's disease and retinal neurodegeneration
    L Guo
    Visual Neurosciences, UCL Institute of Ophthalmology, London UK
    Curr Alzheimer Res 7:3-14. 2010
  6. ncbi Imaging apoptosis in the eye
    M F Cordeiro
    Glaucoma and Retinal Neurodegeneration Research Group, UCL Institute of Ophthalmology, Visual Neurosciences, Bath Street, London, UK
    Eye (Lond) 25:545-53. 2011
  7. ncbi Real-time imaging of single nerve cell apoptosis in retinal neurodegeneration
    M Francesca Cordeiro
    Department of Pathology and Glaucoma and Optic Nerve Head Research Group, Institute of Ophthalmology, University College London, Bath Street, London EC1V 9EL, United Kingdom
    Proc Natl Acad Sci U S A 101:13352-6. 2004
  8. ncbi Technology evaluation: lerdelimumab, Cambridge Antibody Technology
    M Francesca Cordeiro
    Department of Pathology and Department of Glaucoma, Institute of Ophthalmology and Moorfields Eye Hospital, Bath Street, London, EC1V 9EL, UK
    Curr Opin Mol Ther 5:199-203. 2003
  9. ncbi Beyond Mitomycin: TGF-beta and wound healing
    M Francesca Cordeiro
    Department of Pathology, Institute of Ophthalmology and Moorfields Eye Hospital, Bath Street, London EC1V 9EL, UK
    Prog Retin Eye Res 21:75-89. 2002
  10. ncbi Role of transforming growth factor beta in conjunctival scarring
    M Francesca Cordeiro
    Department of Pathology, Moorfields Eye Hospital and Institute of Ophthalmology, Bath Street, London EC1V 9EL, UK
    Clin Sci (Lond) 104:181-7. 2003

Collaborators

Detail Information

Publications26

  1. ncbi Neuroprotection in glaucoma - Is there a future role?
    Abeir Baltmr
    Glaucoma and Retinal Neurodegeneration Research Group, Visual Neurosciences Department, University College London Institute of Ophthalmology, Bath Street, London EC1V 9EL, United Kingdom
    Exp Eye Res 91:554-66. 2010
    ....
  2. ncbi Assessment of neuroprotection in the retina with DARC
    Li Guo
    Glaucoma and Retinal Degeneration Research Group, UCL Institute of Ophthalmology, London, UK
    Prog Brain Res 173:437-50. 2008
    ..Clinical trials of DARC in glaucoma patients are due to start in 2008...
  3. ncbi TGF-beta1, -beta2, and -beta3 in vitro: biphasic effects on Tenon's fibroblast contraction, proliferation, and migration
    M F Cordeiro
    Department of Pathology, Moorfields Eye Hospital and Institute of Ophthalmology, London, United Kingdom
    Invest Ophthalmol Vis Sci 41:756-63. 2000
    ....
  4. ncbi Imaging multiple phases of neurodegeneration: a novel approach to assessing cell death in vivo
    M F Cordeiro
    UCL Institute of Ophthalmology, University College London, London, UK
    Cell Death Dis 1:e3. 2010
    ..Our findings also help to directly observe retinal nerve cell death in patients as an adjunct to refining diagnosis, tracking disease status and assessing therapeutic intervention...
  5. ncbi Alzheimer's disease and retinal neurodegeneration
    L Guo
    Visual Neurosciences, UCL Institute of Ophthalmology, London UK
    Curr Alzheimer Res 7:3-14. 2010
    ....
  6. ncbi Imaging apoptosis in the eye
    M F Cordeiro
    Glaucoma and Retinal Neurodegeneration Research Group, UCL Institute of Ophthalmology, Visual Neurosciences, Bath Street, London, UK
    Eye (Lond) 25:545-53. 2011
    ....
  7. ncbi Real-time imaging of single nerve cell apoptosis in retinal neurodegeneration
    M Francesca Cordeiro
    Department of Pathology and Glaucoma and Optic Nerve Head Research Group, Institute of Ophthalmology, University College London, Bath Street, London EC1V 9EL, United Kingdom
    Proc Natl Acad Sci U S A 101:13352-6. 2004
    ....
  8. ncbi Technology evaluation: lerdelimumab, Cambridge Antibody Technology
    M Francesca Cordeiro
    Department of Pathology and Department of Glaucoma, Institute of Ophthalmology and Moorfields Eye Hospital, Bath Street, London, EC1V 9EL, UK
    Curr Opin Mol Ther 5:199-203. 2003
    ..It also has potential for the treatment of fibrosis, cataract, retinopathy and connective tissue disease...
  9. ncbi Beyond Mitomycin: TGF-beta and wound healing
    M Francesca Cordeiro
    Department of Pathology, Institute of Ophthalmology and Moorfields Eye Hospital, Bath Street, London EC1V 9EL, UK
    Prog Retin Eye Res 21:75-89. 2002
    ..As TGF-beta is such a potent stimulant of scarring, this review examines its biology and role in ocular wound healing and repair, and discusses promising new approaches to modifying its activity...
  10. ncbi Role of transforming growth factor beta in conjunctival scarring
    M Francesca Cordeiro
    Department of Pathology, Moorfields Eye Hospital and Institute of Ophthalmology, Bath Street, London EC1V 9EL, UK
    Clin Sci (Lond) 104:181-7. 2003
    ..This review examines the role of transforming growth factor beta in conjunctival scarring and discusses promising new ways of modifying its activity...
  11. ncbi Novel antisense oligonucleotides targeting TGF-beta inhibit in vivo scarring and improve surgical outcome
    M F Cordeiro
    Department of Pathology and Glaucoma, London, UK
    Gene Ther 10:59-71. 2003
    ..Furthermore, although we have shown this agent to be useful in the eye, it could have widespread applications anywhere in the body where the wound-healing response requires modulation...
  12. ncbi Modulation of wound healing after glaucoma surgery
    P T Khaw
    Wound Healing Research Unit, Department of Pathology, Institute of Ophthalmology and Moorfields Eye Hospital, London, England
    Curr Opin Ophthalmol 12:143-8. 2001
    ..The authors review the changes in how to use antimetabolites to improve safety, and many of the exciting new areas of progress, including growth factor neutralization and future molecular therapies to control wound healing...
  13. ncbi Human antitransforming growth factor beta(2) monoclonal antibody--a new modulator of wound healing in trabeculectomy: a randomized placebo controlled clinical study
    Dilani Siriwardena
    Wound Healing and Glaucoma Research Units, Institute of Ophthalmology and Moorfields Eye Hospital, London, England UK
    Ophthalmology 109:427-31. 2002
    ..CONCLUSIONS: This is the first clinical study of CAT-152 in patients undergoing glaucoma filtration surgery. CAT-152 seems to be well tolerated, and based on these results further multicenter trials are underway...
  14. ncbi En face optical coherence tomography: a new method to analyse structural changes of the optic nerve head in rat glaucoma
    L Guo
    Institute of Ophthalmology, London, UK
    Br J Ophthalmol 89:1210-6. 2005
    ..As far as the authors are aware, this is the first report of scleral canal expansion in a rat model. They suggest eOCT as a novel method for the detection of early changes in the ONH in glaucoma...
  15. ncbi Changes in NMDA receptor contribution to synaptic transmission in the brain in a rat model of glaucoma
    A L Georgiou
    Department of Visual Neuroscience, UCL Institute of Ophthalmology, London, UK
    Neurobiol Dis 39:344-51. 2010
    ..Furthermore, the data underline the need for early therapeutic intervention in order to pre-empt subsequent central functional changes...
  16. ncbi Cystic bleb formation and related complications in limbus- versus fornix-based conjunctival flaps in pediatric and young adult trabeculectomy with mitomycin C
    Anthony P Wells
    Wound Healing Research Unit and Glaucoma Unit, Institute of Ophthalmology and Moorfields Eye Hospital, London, United Kingdom
    Ophthalmology 110:2192-7. 2003
    ..Comparison of fornix- and limbus-based conjunctival flaps with respect to cystic bleb-related complications of trabeculectomy with high-dose mitomycin C (MMC) in pediatric and young adult glaucoma...
  17. ncbi Tracking longitudinal retinal changes in experimental ocular hypertension using the cSLO and spectral domain-OCT
    Li Guo
    Visual Neuroscience, UCL Institute of Ophthalmology, London, United Kingdom
    Invest Ophthalmol Vis Sci 51:6504-13. 2010
    ..The aim of this study was to test, first, whether the outer retina is affected in experimental ocular hypertension (OHT) and, second, whether whole retinal thickness can be used as a surrogate marker of glaucomatous change...
  18. ncbi Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery
    Anna L Mead
    Wound Healing Unit, Institute of Ophthalmology, London, United Kingdom
    Invest Ophthalmol Vis Sci 44:3394-401. 2003
    ....
  19. ncbi Retinal ganglion cell apoptosis in glaucoma is related to intraocular pressure and IOP-induced effects on extracellular matrix
    Li Guo
    Glaucoma and Optic Nerve Head Research Group, Department of Pathology, London, UK
    Invest Ophthalmol Vis Sci 46:175-82. 2005
    ..The findings suggest that abnormal ECM remodeling in the glaucomatous retina may relate to RGC death and support the notion that the retina is a primary site of injury in glaucoma...
  20. ncbi Assessment of neuroprotective effects of glutamate modulation on glaucoma-related retinal ganglion cell apoptosis in vivo
    Li Guo
    Glaucoma and Optic Nerve Head Research Group, Department of Pathology, University College London Institute of Opthamology, London, United Kingdom
    Invest Ophthalmol Vis Sci 47:626-33. 2006
    ..Furthermore, treatments that minimize secondary RGC degeneration may be most useful in glaucoma...
  21. ncbi Targeting amyloid-beta in glaucoma treatment
    Li Guo
    Glaucoma and Retinal Degeneration Research, University College London Institute of Ophthalmology, Bath Street, London EC1V 9EL, United Kingdom
    Proc Natl Acad Sci U S A 104:13444-9. 2007
    ..Furthermore, our work demonstrates that the combination of agents affecting multiple stages in the Abeta pathway may be the most effective strategy in Abeta-related diseases...
  22. ncbi High-resolution ocular imaging: combining advanced optics and microtechnology
    M Francesca Cordeiro
    UCL Institute of Ophthalmology and Western Eye Hospital, London, United Kingdom
    Ophthalmic Surg Lasers Imaging 40:480-8. 2009
    ....
  23. ncbi Neuroprotection in glaucoma: drug-based approaches
    William Cheung
    Glaucoma and Retinal Degeneration Research Group, UCL Institute of Ophthalmology, London, UK
    Optom Vis Sci 85:406-16. 2008
    ..Results of this trial are not yet available. In this review, we will examine currently advocated neuroprotective drug-based strategies in the potential management of glaucoma...
  24. ncbi Accuracy of intraocular pressure measurements in new zealand white rabbits
    K Sheng Lim
    Glaucoma Service, Moorfields Eye Hospital, London, UK
    Invest Ophthalmol Vis Sci 46:2419-23. 2005
    ..The purpose of this study was to establish the most reliable technique, from several currently available methods, of measuring IOP in New Zealand White rabbits...
  25. ncbi Assessment of rat and mouse RGC apoptosis imaging in vivo with different scanning laser ophthalmoscopes
    Annelie Maass
    Glaucoma and Retinal Neurodegeneration Research Group, Institute of Ophthalmology, University College London, London, United Kingdom
    Curr Eye Res 32:851-61. 2007
    ..This study investigated if this technique could be used in the mouse, and whether the Heidelberg Retina Angiograph II (HRAII) was appropriate...
  26. ncbi Back to basics - ephrins, axonal guidance, neuroprotection and glaucoma
    M Francesca Cordeiro
    Br J Ophthalmol 91:1106. 2007