Helen J Cooper
Affiliation: University of Birmingham
- Cooper H. To What Extent is FAIMS Beneficial in the Analysis of Proteins?. J Am Soc Mass Spectrom. 2016;27:566-77 pubmed publisher..Similarly, the application of FAIMS in proteomics and targeted analysis of peptides are considered. ..
- Creese A, Cooper H. Separation of cis and trans Isomers of Polyproline by FAIMS Mass Spectrometry. J Am Soc Mass Spectrom. 2016;27:2071-2074 pubmed..Differentiation of these conformers may be achieved both through use of a cylindrical FAIMS device and a miniaturized ultrahigh field planar FAIMS device. Graphical Abstract ?. ..
- Cooper H, Tatham M, Jaffray E, Heath J, Lam T, Marshall A, et al. Fourier transform ion cyclotron resonance mass spectrometry for the analysis of small ubiquitin-like modifier (SUMO) modification: identification of lysines in RanBP2 and SUMO targeted for modification during the E3 autoSUMOylation reaction. Anal Chem. 2005;77:6310-9 pubmed....
- Powell T, Bowra S, Cooper H. Subcritical Water Hydrolysis of Peptides: Amino Acid Side-Chain Modifications. J Am Soc Mass Spectrom. 2017;: pubmed publisher..In the absence of cysteine and methionine, oxidation of tryptophan was observed. In addition, water loss from aspartic acid and C-terminal amidation were observed in harsher subcritical water conditions. Graphical Abstract ?. ..
- Kocurek K, Stones L, Bunch J, May R, Cooper H. Top-Down LESA Mass Spectrometry Protein Analysis of Gram-Positive and Gram-Negative Bacteria. J Am Soc Mass Spectrom. 2017;28:2066-2077 pubmed publisher..The potential of LESA MS for classification and characterization of novel species is illustrated by the de novo sequencing of a new protein from the unknown species of Staphylococcus. Graphical Abstract ?. ..
- Griffiths R, Kocurek K, Cooper H. Ambient surface mass spectrometry-ion mobility spectrometry of intact proteins. Curr Opin Chem Biol. 2018;42:67-75 pubmed publisher..In this review, we discuss the application of ambient mass spectrometry and ion mobility spectrometry to the analysis of intact proteins, and discuss opportunities and challenges for the field. ..